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TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50208827(NSC-95397 | cid_262093 | N1786 (NSC95397) | CHEMBL...)
Affinity DataIC50: 22nMAssay Description:Inhibition of human Cdc25AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50612010(CHEMBL5271462)
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant CDC25A (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50612011(CHEMBL5288122)
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant CDC25A (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50504348(CHEMBL189010)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant Cdc25A (unknown origin) using OMFP as substrate measured every 30 sec for 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50504348(CHEMBL189010)
Affinity DataIC50: 50nMAssay Description:Inhibition of CDC25A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50208827(NSC-95397 | cid_262093 | N1786 (NSC95397) | CHEMBL...)
Affinity DataIC50: 55nMAssay Description:Inhibition of recombinant human full length GST-tagged CDC25A expressed in Escherichia coli BL21-DE3 pLysS using 3-O-methylfluorescein phosphate as s...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM26613((2E)-3-{3-[dihydroxy(oxo)--stibanyl]phenyl}prop-2-...)
Affinity DataIC50: 110nMAssay Description:Inhibition of N-terminal His-tagged Cdc25a catalytic domain expressed in Escherichia coli BL21(DE3) using 3-O-Methylfluorescein phosphate as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50627011(CHEMBL5423941)
Affinity DataIC50: 150nMAssay Description:Inhibition of full-length recombinant human CDC25A using OMFP as substrate incubated for 5 to 8 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50033731(5,8-Dihydroxy-2-(1-hydroxy-4-methyl-pent-3-enyl)-[...)
Affinity DataIC50: 220nMAssay Description:Inhibition of recombinant Cdc25A (unknown origin) using OMFP as substrate measured every 30 sec for 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM41999(MLS-0111617.0001 | 3-(3,4,5-trihydroxy-6-oxo-9-xan...)
Affinity DataIC50: 240nMAssay Description:Inhibition of recombinant phosphatase activity of Cdc25A catalytic domain expressed in Escherichia coli BL21(DE3) using OMFP as substrate by spectrof...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50341995(5-(2-(dimethylamino)ethylamino)-2,6-dimethylbenzo[...)
Affinity DataIC50: 250nMAssay Description:Inhibition of human Cdc25AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM41999(MLS-0111617.0001 | 3-(3,4,5-trihydroxy-6-oxo-9-xan...)
Affinity DataIC50: 330nMAssay Description:Inhibition of recombinant phosphatase activity of Cdc25A catalytic domain expressed in Escherichia coli BL21(DE3) using OMFP as substrate in presence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50147586((S)-4-{2-[(3R,7S)-1-((2R,3R)-1,5-Dimethyl-hexyl)-4...)
Affinity DataIC50: 440nMAssay Description:Concentration required to inhibit human Cell division cycle 25A activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50342000(4-((S)-2-((1R,3aS,4S,7aR)-4,7a-dimethyl-1-((R)-6-m...)
Affinity DataIC50: 440nMAssay Description:Inhibition of human Cdc25AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50147585((R)-4-{2-[(3R,7R)-1-((2R,3R)-1,5-Dimethyl-hexyl)-4...)
Affinity DataIC50: 480nMAssay Description:Concentration required to inhibit human Cell division cycle 25A activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50504275(CHEMBL4521092)
Affinity DataIC50: 530nMAssay Description:Inhibition of recombinant human Cdc25A using OMFP as substrate preincubated for 5 to 8 mins and measured every 5 mins 60 mins by fluorescence based a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50504277(CHEMBL4566962)
Affinity DataIC50: 540nMAssay Description:Inhibition of recombinant human Cdc25A using OMFP as substrate preincubated for 5 to 8 mins and measured every 5 mins 60 mins by fluorescence based a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50514451(CHEMBL1967787)
Affinity DataIC50: 650nMAssay Description:Inhibition of CDC25A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50150613(CHEMBL179992 | CHEMBL182645 | [(1R,4S,7aR)-1-(1,5-...)
Affinity DataIC50: 700nMAssay Description:Inhibitory concentration against dual-specificity phosphatase Cell division cycle (Cdc) 25AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50097532([17-(1,5-Dimethyl-hexyl)-10,13-dimethyl-hexadecahy...)
Affinity DataIC50: 700nMAssay Description:Inhibitory activity tested against cell division cycle 25A (assay using fluorescein diphosphate (FDP) as substrate)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50012070(CHEMBL295316 | plumbagin | 5-hydroxy-2-methylnapht...)
Affinity DataIC50: 700nMAssay Description:Inhibition of recombinant Cdc25A (unknown origin) using OMFP as substrate measured every 30 sec for 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50388826(CHEMBL2062715)
Affinity DataIC50: 790nMAssay Description:Inhibition of CDC25A in presence of 2 mM DTTMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50341999((R)-5-hydroxy-4-(2-((1R,2R,5S,8aS)-1,2,5-trimethyl...)
Affinity DataIC50: 800nMAssay Description:Inhibition of human Cdc25AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50253622(cid_1383304 | CHEMBL459929 | 2-[4-(4-chlorophenyl)...)
Affinity DataIC50: 800nMAssay Description:Inhibition of human Cdc25AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50253622(cid_1383304 | CHEMBL459929 | 2-[4-(4-chlorophenyl)...)
Affinity DataIC50: 820nMAssay Description:Inhibition of Cdc25A (336-523) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50147582(4-{(R)-2-[(3aR,4S)-1-((1R,2R)-1,5-Dimethyl-hexyl)-...)
Affinity DataIC50: 860nMAssay Description:Concentration required to inhibit human Cell division cycle 25A activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50147583((S)-4-Methylene-3-{2-[(R)-7a-(R)-methyl-1-((R)-5-m...)
Affinity DataIC50: 890nMAssay Description:Concentration required to inhibit human Cell division cycle 25A activity; Value ranges from 0.44 uM to 0.89 uMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50147587((S)-4-{2-[(3R,7R)-1-((2R,3R)-1,5-Dimethyl-hexyl)-4...)
Affinity DataIC50: 890nMAssay Description:Concentration required to inhibit human Cell division cycle 25A activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50150613(CHEMBL179992 | CHEMBL182645 | [(1R,4S,7aR)-1-(1,5-...)
Affinity DataIC50: 900nMAssay Description:Inhibitory concentration against dual-specificity phosphatase Cell division cycle (Cdc) 25AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50097529([17-(1,5-Dimethyl-hexyl)-10,13-dimethyl-hexadecahy...)
Affinity DataIC50: 900nMAssay Description:Inhibitory activity tested against cell division cycle 25A (assay using fluorescein diphosphate (FDP) as substrate)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50129579(2,5-Dihydroxy-3-[7-(2-methyl-benzyl)-1H-indol-3-yl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Eight point inhibitory concentration against Cell division cycle 25A was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50129583(3-[7-(3,7-Dimethyl-octa-2,6-dienyl)-1H-indol-3-yl]...)
Affinity DataIC50: 1.00E+3nMAssay Description:Eight point inhibitory concentration against Cell division cycle 25A was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50342001(1-(biphenyl-4-yl)-3,4-bis(2-hydroxyethylthio)-1H-p...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human Cdc25AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50097528(Dithiocarbonic acid O-[17-(1,5-dimethyl-hexyl)-10,...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory activity tested against cell division cycle 25A (assay using fluorescein diphosphate (FDP) as substrate)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50251724(CHEMBL4066424)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of recombinant human full length GST-tagged CDC25A expressed in Escherichia coli BL21-DE3 pLysS using 3-O-methylfluorescein phosphate as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50504276(CHEMBL4466461)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of recombinant human Cdc25A using OMFP as substrate preincubated for 5 to 8 mins and measured every 5 mins 60 mins by fluorescence based a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50106497(NSC-663284 | 6-Chloro-7-(2-morpholin-4-yl-ethylami...)
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of recombinant human Cdc25A using OMFP as substrate preincubated for 5 to 8 mins and measured every 5 mins 60 mins by fluorescence based a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50177318(2-(4-(7-(4-tetradecylbenzoyl)cyclopenta[d][1,2]oxa...)
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibitory activity against cdc25A phosphataseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50208827(NSC-95397 | cid_262093 | N1786 (NSC95397) | CHEMBL...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of recombinant Cdc25A (unknown origin) using OMFP as substrate measured every 30 sec for 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50251697(CHEMBL4093222)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of recombinant human full length GST-tagged CDC25A expressed in Escherichia coli BL21-DE3 pLysS using 3-O-methylfluorescein phosphate as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50504351(CHEMBL100206)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of recombinant Cdc25A (unknown origin) using OMFP as substrate measured every 30 sec for 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50504351(CHEMBL100206)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of CDC25A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50261103((Z)-2-(1-hexadecyl-2-oxoindolin-3-ylidene)acetic a...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human Cdc25A phosphatase activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50251671(CHEMBL4097725)
Affinity DataIC50: 1.61E+3nMAssay Description:Inhibition of recombinant human full length GST-tagged CDC25A expressed in Escherichia coli BL21-DE3 pLysS using 3-O-methylfluorescein phosphate as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50612003(CHEMBL5278031)
Affinity DataIC50: 1.68E+3nMAssay Description:Inhibition of CDC25A (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50261059((Z)-2-(2-oxo-1-tetradecylindolin-3-ylidene)acetic ...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human Cdc25A phosphatase activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50261013((E)-2-(1-hexadecyl-2-oxoindolin-3-ylidene)acetic a...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human Cdc25A phosphatase activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50341996((2R,3R)-2,3-Dibromo-3-methyl-1,1-dioxo-1lambda*6*-...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human Cdc25AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50612005(CHEMBL5269565)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of CDC25A (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50612004(CHEMBL5284545)
Affinity DataIC50: 2.01E+3nMAssay Description:Inhibition of CDC25A (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
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