Compile Data Set for Download or QSAR
Report error Found 45 of ic50 data for polymerid = 4782,50006131
TargetInward rectifier potassium channel 2(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM65870(cid_17367817 | (4-Methoxy-benzyl)-naphthalen-1-ylm...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of mouse Kir2.1 expressed in HEK293 cells by patch clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInward rectifier potassium channel 2(Human)
Sareum

Curated by ChEMBL
LigandPNGBDBM328993(US9663503, Compound 1 | 5-[[4-[[(2R)-morpholin-2-y...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human Kir2.1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInward rectifier potassium channel 2(Human)
Sareum

Curated by ChEMBL
LigandPNGBDBM600745(US11632953, Compound 1 | US11632953, Compound VU04...)
Affinity DataIC50: 1.13E+4nMAssay Description:The thallium flux assay is an in vitro method of measuring conductance through a potassium ion channel. Potassium channels are also permeable to thal...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInward rectifier potassium channel 2(Human)
Sareum

Curated by ChEMBL
LigandPNGBDBM600745(US11632953, Compound 1 | US11632953, Compound VU04...)
Affinity DataIC50: 1.27E+4nMAssay Description:The thallium flux assay is an in vitro method of measuring conductance through a potassium ion channel. Potassium channels are also permeable to thal...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInward rectifier potassium channel 2(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM65858(MLS000557943 | N-[2-[5-[(4-chlorophenyl)methylthio...)
Affinity DataIC50: 1.58E+4nMAssay Description:Data Source: Johns Hopkins Ion Channel Center (JHICC) BioAssay Type: Confirmatory, Confirmatory Screening, Multiple Concentration Activity Observed. ...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetInward rectifier potassium channel 2(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM65871(cid_2942461 | 5-bromanyl-N-(1-phenylethyl)thiophen...)
Affinity DataIC50: 1.98E+4nMAssay Description:Data Source: Johns Hopkins Ion Channel Center (JHICC) BioAssay Type: Confirmatory, Confirmatory Screening, Multiple Concentration Activity Observed. ...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetInward rectifier potassium channel 2(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM65874(4-methyl-2-[[2-[(5-methyl-2-oxidanyl-phenyl)methyl...)
Affinity DataIC50: 2.15E+4nMAssay Description:Data Source: Johns Hopkins Ion Channel Center (JHICC) BioAssay Type: Confirmatory, Confirmatory Screening, Multiple Concentration Activity Observed. ...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetInward rectifier potassium channel 2(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM65865((E)-N-[(4-methoxyphenyl)methyl]-3-phenyl-prop-2-en...)
Affinity DataIC50: 2.23E+4nMAssay Description:Data Source: Johns Hopkins Ion Channel Center (JHICC) BioAssay Type: Confirmatory, Confirmatory Screening, Multiple Concentration Activity Observed. ...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetInward rectifier potassium channel 2(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM65861(oxalic acid;1-[3-(3-phenoxyphenoxy)propylamino]-2-...)
Affinity DataIC50: 2.36E+4nMAssay Description:Data Source: Johns Hopkins Ion Channel Center (JHICC) BioAssay Type: Confirmatory, Confirmatory Screening, Multiple Concentration Activity Observed. ...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetInward rectifier potassium channel 2(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM65872(1-[(4-fluorophenyl)methylamino]-3-(4-methylphenoxy...)
Affinity DataIC50: 2.46E+4nMAssay Description:Data Source: Johns Hopkins Ion Channel Center (JHICC) BioAssay Type: Confirmatory, Confirmatory Screening, Multiple Concentration Activity Observed. ...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetInward rectifier potassium channel 2(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM65868(SMR000516693 | cid_2841713 | 4-bromanyl-N-(1-pheny...)
Affinity DataIC50: 2.56E+4nMAssay Description:Data Source: Johns Hopkins Ion Channel Center (JHICC) BioAssay Type: Confirmatory, Confirmatory Screening, Multiple Concentration Activity Observed. ...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetInward rectifier potassium channel 2(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM65859(2-cyclopropyl-1-(2-phenylethyl)benzimidazole | MLS...)
Affinity DataIC50: 2.57E+4nMAssay Description:Data Source: Johns Hopkins Ion Channel Center (JHICC) BioAssay Type: Confirmatory, Confirmatory Screening, Multiple Concentration Activity Observed. ...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetInward rectifier potassium channel 2(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM65870(cid_17367817 | (4-Methoxy-benzyl)-naphthalen-1-ylm...)
Affinity DataIC50: 2.69E+4nMAssay Description:Data Source: Johns Hopkins Ion Channel Center (JHICC) BioAssay Type: Confirmatory, Confirmatory Screening, Multiple Concentration Activity Observed. ...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetInward rectifier potassium channel 2(Human)
Sareum

Curated by ChEMBL
LigandPNGBDBM50050530(CHEMBL3188857)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Kir2.1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInward rectifier potassium channel 2(Human)
Sareum

Curated by ChEMBL
LigandPNGBDBM50312105(2-methoxy-N-(3-(3-methylbenzamido)phenyl)benzamide...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Kir2.1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInward rectifier potassium channel 2(Human)
Sareum

Curated by ChEMBL
LigandPNGBDBM50050534(CHEMBL3183773)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Kir2.1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInward rectifier potassium channel 2(Human)
Sareum

Curated by ChEMBL
LigandPNGBDBM50050539(CHEMBL3187891)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Kir2.1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInward rectifier potassium channel 2(Human)
Sareum

Curated by ChEMBL
LigandPNGBDBM50258216(CHEMBL4105630)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Kir2.1 (unknown origin) by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInward rectifier potassium channel 2(Human)
Sareum

Curated by ChEMBL
LigandPNGBDBM600747(VU0650729 | US11632953, Compound 4)
Affinity DataIC50: 3.00E+4nMAssay Description:The thallium flux assay is an in vitro method of measuring conductance through a potassium ion channel. Potassium channels are also permeable to thal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetInward rectifier potassium channel 2(Human)
Sareum

Curated by ChEMBL
LigandPNGBDBM600748(VU0650730 | US11632953, Compound 5)
Affinity DataIC50: 3.00E+4nMAssay Description:The thallium flux assay is an in vitro method of measuring conductance through a potassium ion channel. Potassium channels are also permeable to thal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetInward rectifier potassium channel 2(Human)
Sareum

Curated by ChEMBL
LigandPNGBDBM600751(VU0652954 | US11632953, Compound 9)
Affinity DataIC50: 3.00E+4nMAssay Description:The thallium flux assay is an in vitro method of measuring conductance through a potassium ion channel. Potassium channels are also permeable to thal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetInward rectifier potassium channel 2(Human)
Sareum

Curated by ChEMBL
LigandPNGBDBM600754(VU0652942 | US11632953, Compound 12)
Affinity DataIC50: 3.00E+4nMAssay Description:The thallium flux assay is an in vitro method of measuring conductance through a potassium ion channel. Potassium channels are also permeable to thal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetInward rectifier potassium channel 2(Human)
Sareum

Curated by ChEMBL
LigandPNGBDBM600755(VU0652943 | US11632953, Compound 13)
Affinity DataIC50: 3.00E+4nMAssay Description:The thallium flux assay is an in vitro method of measuring conductance through a potassium ion channel. Potassium channels are also permeable to thal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetInward rectifier potassium channel 2(Human)
Sareum

Curated by ChEMBL
LigandPNGBDBM50312125(3-chloro-N-(3-(3-methylbenzamido)phenyl)benzamide ...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Kir2.1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInward rectifier potassium channel 2(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM65863(3-[[4-(4-fluorophenyl)piperazin-1-yl]methyl]-1H-in...)
Affinity DataIC50: 3.07E+4nMAssay Description:Data Source: Johns Hopkins Ion Channel Center (JHICC) BioAssay Type: Confirmatory, Confirmatory Screening, Multiple Concentration Activity Observed. ...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetInward rectifier potassium channel 2(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM43753(MLS000081058 | cid_665867 | N-benzyl-6-methyl-1H-b...)
Affinity DataIC50: 3.34E+4nMAssay Description:Data Source: Johns Hopkins Ion Channel Center (JHICC) BioAssay Type: Confirmatory, Confirmatory Screening, Multiple Concentration Activity Observed. ...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetInward rectifier potassium channel 2(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM65857(MLS000535503 | oxalic acid;N-[3-(4-phenylmethoxyph...)
Affinity DataIC50: 3.35E+4nMAssay Description:Data Source: Johns Hopkins Ion Channel Center (JHICC) BioAssay Type: Confirmatory, Confirmatory Screening, Multiple Concentration Activity Observed. ...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetInward rectifier potassium channel 2(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM65855(SMR000033695 | cid_6602913 | N-(4-methoxyphenyl)-4...)
Affinity DataIC50: 3.40E+4nMAssay Description:Data Source: Johns Hopkins Ion Channel Center (JHICC) BioAssay Type: Confirmatory, Confirmatory Screening, Multiple Concentration Activity Observed. ...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetInward rectifier potassium channel 2(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM65873(SMR000555601 | N-[2-(1,3-benzodioxol-5-yl)ethyl]-N...)
Affinity DataIC50: 3.47E+4nMAssay Description:Data Source: Johns Hopkins Ion Channel Center (JHICC) BioAssay Type: Confirmatory, Confirmatory Screening, Multiple Concentration Activity Observed. ...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetInward rectifier potassium channel 2(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM65856(SMR000078102 | MLS000050654 | 3-chloro-4-(1-ethylb...)
Affinity DataIC50: 3.56E+4nMAssay Description:Data Source: Johns Hopkins Ion Channel Center (JHICC) BioAssay Type: Confirmatory, Confirmatory Screening, Multiple Concentration Activity Observed. ...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetInward rectifier potassium channel 2(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM65862(SMR000427856 | cid_248400 | MLS001047467 | 2-[(2,4...)
Affinity DataIC50: 3.76E+4nMAssay Description:Data Source: Johns Hopkins Ion Channel Center (JHICC) BioAssay Type: Confirmatory, Confirmatory Screening, Multiple Concentration Activity Observed. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PCBioAssay
TargetInward rectifier potassium channel 2(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM65867(N-[(4-chlorophenyl)methyl]-1-(phenylmethyl)-4-pipe...)
Affinity DataIC50: 3.77E+4nMAssay Description:Data Source: Johns Hopkins Ion Channel Center (JHICC) BioAssay Type: Confirmatory, Confirmatory Screening, Multiple Concentration Activity Observed. ...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetInward rectifier potassium channel 2(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM65860(MLS000693878 | 4-methylsulfanyl-N-(1-phenylethyl)b...)
Affinity DataIC50: 4.30E+4nMAssay Description:Data Source: Johns Hopkins Ion Channel Center (JHICC) BioAssay Type: Confirmatory, Confirmatory Screening, Multiple Concentration Activity Observed. ...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetInward rectifier potassium channel 2(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM65869(2,8-dimethyl-N-(4-methylphenyl)quinolin-4-amine | ...)
Affinity DataIC50: 4.31E+4nMAssay Description:Data Source: Johns Hopkins Ion Channel Center (JHICC) BioAssay Type: Confirmatory, Confirmatory Screening, Multiple Concentration Activity Observed. ...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetInward rectifier potassium channel 2(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM65854(4-[[4-ethyl-5-(phenoxymethyl)-1,2,4-triazol-3-yl]s...)
Affinity DataIC50: 4.83E+4nMAssay Description:Data Source: Johns Hopkins Ion Channel Center (JHICC) BioAssay Type: Confirmatory, Confirmatory Screening, Multiple Concentration Activity Observed. ...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetInward rectifier potassium channel 2(Human)
Sareum

Curated by ChEMBL
LigandPNGBDBM50442600(CHEMBL2441437 | US9056859, 1)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Kir2.1 channel (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInward rectifier potassium channel 2(Human)
Sareum

Curated by ChEMBL
LigandPNGBDBM162872(US9056859, 72)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Kir2.1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetInward rectifier potassium channel 2(Human)
Sareum

Curated by ChEMBL
LigandPNGBDBM155928(US9018211, 52)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Kir2.1 potassium channel (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetInward rectifier potassium channel 2(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM65864(N-(1-adamantyl)-1-propyl-4-piperidinamine | SMR000...)
Affinity DataIC50: 5.42E+4nMAssay Description:Data Source: Johns Hopkins Ion Channel Center (JHICC) BioAssay Type: Confirmatory, Confirmatory Screening, Multiple Concentration Activity Observed. ...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetInward rectifier potassium channel 2(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM65866(SMR000514216 | cid_767981 | MLS001207781 | 1-(4-Fl...)
Affinity DataIC50: 5.85E+4nMAssay Description:Data Source: Johns Hopkins Ion Channel Center (JHICC) BioAssay Type: Confirmatory, Confirmatory Screening, Multiple Concentration Activity Observed. ...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetInward rectifier potassium channel 2(Human)
Sareum

Curated by ChEMBL
LigandPNGBDBM50249183(CHEMBL4069245)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Kir2.1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInward rectifier potassium channel 2(Human)
Sareum

Curated by ChEMBL
LigandPNGBDBM50257064(CHEMBL2386850)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human Kir2.1 expressed in CHO cells by automated patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInward rectifier potassium channel 2(Human)
Sareum

Curated by ChEMBL
LigandPNGBDBM50204281(CHEMBL3933749)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Kir2.1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInward rectifier potassium channel 2(Human)
Sareum

Curated by ChEMBL
LigandPNGBDBM50391771(CHEMBL2146754)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Kir2.1 expressed in HEK293 cells assessed as inhibition of thallium efflux by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInward rectifier potassium channel 2(Human)
Sareum

Curated by ChEMBL
LigandPNGBDBM50391770(CHEMBL2146755 | US9073882, 1)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Kir2.1 expressed in HEK293 cells assessed as inhibition of thallium efflux by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed