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Report error Found 603 of ic50 data for polymerid = 4755

Nucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

BDBM50185(2-hydroxy-4-[[4-[(5Z)-5-[(E)-2-methyl-3-phenylprop...)

IC50: 20.1nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics Source Affiliation: Sanford-Burnham Medical Research Institute Network: NIH Molecular Lib...More data for this Ligand-Target Pair

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Nucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

BDBM62265(cid_709072 | MLS-0412171.0001 | 2-(4-tert-butylphe...)

IC50: 31.8nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair

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Nucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

BDBM44245(methyl 2-[(4E)-1-(1,3-benzothiazol-2-yl)-4-[1-[(4-...)

IC50: 39.1nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair

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Nucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

BDBM52783(methyl 2-[(4E)-4-(1-anilinoethylidene)-1-(1,3-benz...)

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Nucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

BDBM62288(cid_44229055 | MLS-0412185.0001 | 4-(3,4-dihydro-1...)

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Nucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

BDBM62271(MLS-0378444.0001 | cid_24817336 | N-[1-(3,4-dimeth...)

IC50: 43.1nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair

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Nucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

BDBM58651(SMR000646238 | 4-[[4-[(5Z)-5-[(4-ethylphenyl)methy...)

IC50: 71.8nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics Source Affiliation: Sanford-Burnham Medical Research Institute Network: NIH Molecular Lib...More data for this Ligand-Target Pair

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Nucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

BDBM62288(cid_44229055 | MLS-0412185.0001 | 4-(3,4-dihydro-1...)

IC50: 80nMAssay Description:Inhibition of NOD1 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair

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Nucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

BDBM62288(cid_44229055 | MLS-0412185.0001 | 4-(3,4-dihydro-1...)

IC50: 80nMAssay Description:Inhibition of NOD-1 mediated NFkappaB activation in HEK293T cells assessed as inhibition of gamma-tri-DAP-induced luciferase activity after 14 hrs by...More data for this Ligand-Target Pair

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Nucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

BDBM62170(MLS-0425609.0001 | cid_1088439 | 1-(4-chlorophenyl...)

IC50: 90nMAssay Description:Inhibition of NOD1 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair

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Nucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

BDBM62170(MLS-0425609.0001 | cid_1088439 | 1-(4-chlorophenyl...)

IC50: 90nMAssay Description:Inhibition of NOD-1 mediated NFkappaB activation in HEK293T cells assessed as inhibition of gamma-tri-DAP-induced luciferase activity after 14 hrs by...More data for this Ligand-Target Pair

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Nucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

BDBM62170(MLS-0425609.0001 | cid_1088439 | 1-(4-chlorophenyl...)

IC50: 94nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair

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Nucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

BDBM54393(cid_3390551 | N-[amino-[(5-methyl-1,3-benzoxazol-2...)

IC50: 94.9nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair

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Nucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

BDBM62269(MLS-0384970.0001 | cid_24792090 | N-[1-(2,3-dimeth...)

IC50: 98.3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair

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Nucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

BDBM45060(4-[4-[(5Z)-5-[(E)-2-methyl-3-phenyl-prop-2-enylide...)

IC50: 105nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics Source Affiliation: Sanford-Burnham Medical Research Institute Network: NIH Molecular Lib...More data for this Ligand-Target Pair

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Nucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

BDBM50556245(CHEMBL4749022)

IC50: 140nMAssay Description:Antagonist activity at NOD1 in HEK-Blue hNOD1 cells assessed as inhibition of C12-iE-DAP-induced NFkappaB activation-mediated SEAP release preincubat...More data for this Ligand-Target Pair

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Nucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

BDBM62310(cid_44251464 | N-[1-(2-fluorophenyl)-4,5,6,7-tetra...)

IC50: 146nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair

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Nucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

BDBM54409(ethyl 4-[[4-(3,4-dihydro-1H-isoquinolin-2-ylmethyl...)

IC50: 150nMAssay Description:Inhibition of NOD1 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair

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Nucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

BDBM54409(ethyl 4-[[4-(3,4-dihydro-1H-isoquinolin-2-ylmethyl...)

IC50: 150nMAssay Description:Inhibition of NOD-1 mediated NFkappaB activation in HEK293T cells assessed as inhibition of gamma-tri-DAP-induced luciferase activity after 14 hrs by...More data for this Ligand-Target Pair

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Nucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

BDBM64828(4-[4-[(5Z)-5-[(3,4-dimethoxyphenyl)methylidene]-4-...)

IC50: 151nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics Source Affiliation: Sanford-Burnham Medical Research Institute Network: NIH Molecular Lib...More data for this Ligand-Target Pair

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Nucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

BDBM54409(ethyl 4-[[4-(3,4-dihydro-1H-isoquinolin-2-ylmethyl...)

IC50: 152nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair

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Nucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

BDBM62233(4-chloro-1-hydroxy-N-(2-methyl-5-nitrophenyl)-2-na...)

IC50: 170nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair

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Nucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

BDBM50044276(CHEMBL3321858)

IC50: 200nMAssay Description:Inhibition of NOD1 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair

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Nucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

BDBM50556243(CHEMBL4763527)

IC50: 210nMAssay Description:Antagonist activity at NOD1 in HEK-Blue hNOD1 cells assessed as inhibition of C12-iE-DAP-induced NFkappaB activation-mediated SEAP release preincubat...More data for this Ligand-Target Pair

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Nucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

BDBM50565444(CHEMBL4779776)

IC50: 230nMAssay Description:Antagonist activity at human NOD1 in HEK-Blue hNOD1 cells assessed as secreted alkaline phosphatase reporter activity preincubated for 3 hrs followed...More data for this Ligand-Target Pair

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Nucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

BDBM62272(N-[1-(4-tert-butylphenyl)-4,5,6,7-tetrahydroindazo...)

IC50: 232nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair

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Nucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

BDBM61153(MLS001034563 | SMR000664707 | 3-[4-[(5Z)-5-[(4-met...)

IC50: 240nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics Source Affiliation: Sanford-Burnham Medical Research Institute Network: NIH Molecular Lib...More data for this Ligand-Target Pair

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Nucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

BDBM62261(MLS-0412148.0001 | cid_44182149 | 4-(3,4-dihydro-1...)

IC50: 240nMAssay Description:Inhibition of NOD1 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair

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Nucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

BDBM62261(MLS-0412148.0001 | cid_44182149 | 4-(3,4-dihydro-1...)

IC50: 240nMAssay Description:Inhibition of NOD-1 mediated NFkappaB activation in HEK293T cells assessed as inhibition of gamma-tri-DAP-induced luciferase activity after 14 hrs by...More data for this Ligand-Target Pair

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Nucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

BDBM62261(MLS-0412148.0001 | cid_44182149 | 4-(3,4-dihydro-1...)

IC50: 243nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair

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Nucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

BDBM59542(SMR000523991 | cid_1088438 | MLS001201458 | 1-(4-m...)

IC50: 257nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair

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Nucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

BDBM62251(MLS-0412140.0001 | cid_44182145 | cyclopropyl-[2-m...)

IC50: 260nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair

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Nucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

BDBM54367(SMR000415593 | MLS000778899 | cid_16460826 | 2-[(4...)

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Nucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

BDBM62251(MLS-0412140.0001 | cid_44182145 | cyclopropyl-[2-m...)

IC50: 260nMAssay Description:Inhibition of NOD1 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair

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Nucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

BDBM62251(MLS-0412140.0001 | cid_44182145 | cyclopropyl-[2-m...)

IC50: 260nMAssay Description:Inhibition of NOD-1 mediated NFkappaB activation in HEK293T cells assessed as inhibition of gamma-tri-DAP-induced luciferase activity after 14 hrs by...More data for this Ligand-Target Pair

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Nucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

BDBM50556242(CHEMBL4788738)

IC50: 260nMAssay Description:Antagonist activity at NOD1 in HEK-Blue hNOD1 cells assessed as inhibition of C12-iE-DAP-induced NFkappaB activation-mediated SEAP release preincubat...More data for this Ligand-Target Pair

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Nucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

BDBM50556244(CHEMBL4776782)

IC50: 270nMAssay Description:Antagonist activity at NOD1 in HEK-Blue hNOD1 cells assessed as inhibition of C12-iE-DAP-induced NFkappaB activation-mediated SEAP release preincubat...More data for this Ligand-Target Pair

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Nucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

BDBM62279([2-[2,5-dimethyl-1-(thiophen-2-ylmethyl)pyrrol-3-y...)

IC50: 285nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair

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Nucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

BDBM54484(N-[1-(2,3-dimethylphenyl)-4,5,6,7-tetrahydroindazo...)

IC50: 289nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair

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Nucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

BDBM61652(4-[4-[(5Z)-5-benzylidene-4-oxo-2-sulfanylidene-1,3...)

IC50: 295nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics Source Affiliation: Sanford-Burnham Medical Research Institute Network: NIH Molecular Lib...More data for this Ligand-Target Pair

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Nucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

BDBM64829(4-[[4-[(5Z)-5-(1,3-benzodioxol-5-ylmethylidene)-4-...)

IC50: 300nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics Source Affiliation: Sanford-Burnham Medical Research Institute Network: NIH Molecular Lib...More data for this Ligand-Target Pair

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Nucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

BDBM54409(ethyl 4-[[4-(3,4-dihydro-1H-isoquinolin-2-ylmethyl...)

IC50: 335nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair

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Nucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

BDBM41612(MLS000580544 | 4-(3,4-dihydro-1H-isoquinolin-2-ylm...)

IC50: 347nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair

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Nucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

BDBM62298(cid_3115883 | 2-[[(4-bromophenyl)-oxomethyl]amino]...)

IC50: 375nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair

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Nucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

BDBM62302(cid_1106356 | MLS-0425608.0001 | N-(4-bromophenyl)...)

IC50: 399nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair

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Nucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

BDBM50044275(CHEMBL3321857)

IC50: 400nMAssay Description:Inhibition of NOD1 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair

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Nucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

BDBM62234(cid_2211281 | 4-(3,4-dihydro-1H-isoquinolin-2-ylme...)

IC50: 418nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair

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Nucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

BDBM50312(SMR000236235 | MLS000720339 | cid_7110073 | methyl...)

IC50: 429nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair

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Nucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

BDBM50239687(CHEMBL4076733)

IC50: 430nMAssay Description:Antagonist activity at human NOD1 expressed in HEK-blue cells assessed as inhibition of C12-iE-DAP-stimulated cell activation preincubated for 3 hrs ...More data for this Ligand-Target Pair

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Nucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

BDBM62232(4-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-N-(4-pip...)

IC50: 432nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair

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Targets 1▿
- Nucleotide-binding oligomerization domain-containing protein 1 603
Publications 13▿
- PubChem Bioassay (2010) 303
- ACS Med Chem Lett 2: 780-785 (2011) 68
- PubChem Bioassay (2010) 60
- PubChem Bioassay (2010) 40
- J Med Chem 60: 5162-5192 (2017) 30
- Eur J Med Chem 207: (2020) 28
- J Med Chem 57: 6897-918 (2014) 20
- Eur J Med Chem 204: (2020) 18
- Eur J Med Chem 190: (2020) 15
- Bioorg Med Chem 24: 5221-5234 (2016) 9
- J Med Chem 57: 7325-41 (2014) 6
- PubChem Bioassay (2010) 5
- J Med Chem 61: 1519-1540 (2018) 1
Institutions 6▿
- Burnham Center For Chemical Genomics 408
- Peking Union Medical College 76
- TBA 68
- University of Ljubljana 44
- University of Kansas 6
- Shenzhen Salubris Pharmaceuticals Co. 1
Affinity: 20 to 5.0E+4 nM▿
- IC50 603
- Affinity ≤ nM
Xtal structures: 0
Docked structures: 0
Catalog Cmpds: 253