Compile Data Set for Download or QSAR
Report error Found 312 of ic50 data for polymerid = 4676
LigandPNGBDBM33024(SMR000445568 | Punicalin | MLS000697664 | cid_5388...)
Affinity DataIC50: 176nMAssay Description:Project Title: A screen for modulators of human Rad51, a key DNA repair protein Application Number: MH084119 Assay Submitter: Dr. Alex Mazin Submitte...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
LigandPNGBDBM50424496(CHEMBL2316725)
Affinity DataIC50: 250nMAssay Description:Inhibition of human RAD51 binding to single stranded DNA by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50424497(CHEMBL2316724)
Affinity DataIC50: 370nMAssay Description:Inhibition of human RAD51 binding to single stranded DNA by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50118214(DIDS | CHEMBL133930)
Affinity DataIC50: 750nMAssay Description:Inhibition of RAD51 (unknown origin) assessed as reduction in novel 58/33-dsDNA formation incubated for 1 hr by electrophoresis based DNA strand exch...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50424498(CHEMBL2316723)
Affinity DataIC50: 810nMAssay Description:Inhibition of human RAD51 binding to single stranded DNA by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50118214(DIDS | CHEMBL133930)
Affinity DataIC50: 900nMAssay Description:Inhibition of RAD51 (unknown origin) using labeled 100-ss DNA as substrate assessed as reduction in DNA D-loop formation by [gamma-32P]ATP based scin...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50118214(DIDS | CHEMBL133930)
Affinity DataIC50: 900nMAssay Description:Inhibition of wild type human RAD51 expressed in Escherichia coli BL21-DE3 using 100 bp ssDNA probe as substrate assessed as prevention of D-loop for...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50424499(CHEMBL2316722)
Affinity DataIC50: 930nMAssay Description:Inhibition of human RAD51 binding to single stranded DNA by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50416570(CHEMBL1215819)
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of human RAD51 assessed as dissociation of protein/single-stranded oligo(AGT)12 complex formation by fluorescence polarimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50614578(CHEMBL5280045)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of RAD51 (unknown origin) assessed as reduction in novel 58/33-dsDNA formation incubated for 1 hr by electrophoresis based DNA strand exch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
LigandPNGBDBM51319(MLS000037525 | MLS001401404 | ethyl 2-(7-benzyl-3-...)
Affinity DataIC50: 1.40E+3nMAssay Description:Project Title: A screen for modulators of human Rad51, a key DNA repair protein Application Number: MH084119 Assay Submitter: Dr. Alex Mazin Submitte...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
LigandPNGBDBM50424500(CHEMBL2316721)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human RAD51 binding to single stranded DNA by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50416570(CHEMBL1215819)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human RAD51 assessed as dissociation of protein/single-stranded poly-(d-epsilonA) complex formation by fluorescence polarimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50416568(CHEMBL1215817)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human RAD51 assessed as dissociation of protein/single-stranded oligo(AGT)12 complex formation by fluorescence polarimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50416561(CHEMBL1215810)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human RAD51 assessed as dissociation of protein/single-stranded DNA complex formation by fluorescence polarimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50424501(CHEMBL2316720)
Affinity DataIC50: 2.14E+3nMAssay Description:Inhibition of human RAD51 binding to single stranded DNA by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50614586(CHEMBL5287027)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of RAD51 (unknown origin) using labeled 100-ss DNA as substrate assessed as reduction in DNA D-loop formation by [gamma-32P]ATP based scin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
LigandPNGBDBM50416568(CHEMBL1215817)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human RAD51 assessed as dissociation of protein/single-stranded poly-(d-epsilonA) complex formation by fluorescence polarimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50416569(CHEMBL1215818)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human RAD51 assessed as dissociation of protein/single-stranded oligo(AGT)12 complex formation by fluorescence polarimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50416566(CHEMBL1215815)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human RAD51 assessed as dissociation of protein/single-stranded oligo(AGT)12 complex formation by fluorescence polarimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50184320(CHEMBL3823105)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of RAD51-mediated homologous recombination in human HEK293-DR-GFP cells transfected with pCBASce expressing I-Sce-I after 24 hrs following...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50614584(CHEMBL5277728)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of RAD51 (unknown origin) assessed as reduction in novel 58/33-dsDNA formation incubated for 1 hr by electrophoresis based DNA strand exch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
LigandPNGBDBM50424504(CHEMBL2316738)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human RAD51 binding to single stranded DNA by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50416562(CHEMBL1215811)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human RAD51 assessed as dissociation of protein/single-stranded DNA complex formation by fluorescence polarimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM51314(MLS000727607 | SMR000306304 | (6-chloro-2-phenyl-1...)
Affinity DataIC50: 3.66E+3nMAssay Description:Project Title: A screen for modulators of human Rad51, a key DNA repair protein Application Number: MH084119 Assay Submitter: Dr. Alex Mazin Submitte...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
LigandPNGBDBM50614586(CHEMBL5287027)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of RAD51 (unknown origin) assessed as reduction in novel 58/33-dsDNA formation incubated for 1 hr by electrophoresis based DNA strand exch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
LigandPNGBDBM50614578(CHEMBL5280045)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of RAD51 (unknown origin) using labeled 100-ss DNA as substrate assessed as reduction in DNA D-loop formation by [gamma-32P]ATP based scin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
LigandPNGBDBM50416569(CHEMBL1215818)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human RAD51 assessed as dissociation of protein/single-stranded poly-(d-epsilonA) complex formation by fluorescence polarimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50424503(CHEMBL2316739)
Affinity DataIC50: 5.29E+3nMAssay Description:Inhibition of human RAD51 binding to single stranded DNA by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50056939(NSC-92186 | CHEMBL176570 | Parellic acid, 3 | cid_...)
Affinity DataIC50: 5.45E+3nMAssay Description:Project Title: A screen for modulators of human Rad51, a key DNA repair protein Application Number: MH084119 Assay Submitter: Dr. Alex Mazin Submitte...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
LigandPNGBDBM50416564(CHEMBL1215813)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human RAD51 assessed as dissociation of protein/single-stranded oligo(AGT)12 complex formation by fluorescence polarimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM48804(MLS000709026 | 3-(phenylmethyl)-2-[(E)-2-pyridin-3...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human RAD51More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50055659(CHEMBL11252 | 2N-[5-(3-amino-3-iminopropylcarbamoy...)
Affinity DataIC50: 6.37E+3nMAssay Description:Project Title: A screen for modulators of human Rad51, a key DNA repair protein Application Number: MH084119 Assay Submitter: Dr. Alex Mazin Submitte...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
LigandPNGBDBM34194(3-chloro-1-(3,4-dichlorophenyl)-4-(4-methyl-1-pipe...)
Affinity DataIC50: 6.43E+3nMAssay Description:Inhibition of human RAD51 binding to single stranded DNA by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50614584(CHEMBL5277728)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of RAD51 (unknown origin) using labeled 100-ss DNA as substrate assessed as reduction in DNA D-loop formation by [gamma-32P]ATP based scin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
LigandPNGBDBM39120(3-chloro-1-(3,4-dichlorophenyl)-4-morpholin-4-ylpy...)
Affinity DataIC50: 6.82E+3nMAssay Description:Inhibition of human RAD51 binding to single stranded DNA by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50416566(CHEMBL1215815)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human RAD51 assessed as dissociation of protein/single-stranded poly-(d-epsilonA) complex formation by fluorescence polarimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50424506(CHEMBL2316736)
Affinity DataIC50: 7.91E+3nMAssay Description:Inhibition of human RAD51 binding to single stranded DNA by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM29673(NSC-87509 | CHEMBL172439 | cid_5320418 | 1,4,10-Tr...)
Affinity DataIC50: 8.02E+3nMAssay Description:Project Title: A screen for modulators of human Rad51, a key DNA repair protein Application Number: MH084119 Assay Submitter: Dr. Alex Mazin Submitte...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
LigandPNGBDBM50424507(CHEMBL2316735)
Affinity DataIC50: 8.32E+3nMAssay Description:Inhibition of human RAD51 binding to single stranded DNA by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50184342(CHEMBL3823002)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of human N-terminal 6-histidine/Avi-tagged recombinant RAD51 expressed in Escherichia coli BL21(DE3) assessed as D-loop formation using 5'...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50056922(cid_73677 | CHEMBL173530 | 1,4-Dihydroxy-10-methox...)
Affinity DataIC50: 8.74E+3nMAssay Description:Project Title: A screen for modulators of human Rad51, a key DNA repair protein Application Number: MH084119 Assay Submitter: Dr. Alex Mazin Submitte...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
LigandPNGBDBM50184343(CHEMBL3822706)
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of human N-terminal 6-histidine/Avi-tagged recombinant RAD51 expressed in Escherichia coli BL21(DE3) assessed as D-loop formation using 5'...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50424505(CHEMBL2316737)
Affinity DataIC50: 9.94E+3nMAssay Description:Inhibition of human RAD51 binding to single stranded DNA by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50614580(CHEMBL5269627)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of RAD51 (unknown origin) assessed as reduction in novel 58/33-dsDNA formation incubated for 1 hr by electrophoresis based DNA strand exch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
LigandPNGBDBM44459(1,1,3-trimethyl-2-[(E,3Z)-3-(1,3,3-trimethyl-2-ind...)
Affinity DataIC50: 1.06E+4nMAssay Description:Project Title: A screen for modulators of human Rad51, a key DNA repair protein Application Number: MH084119 Assay Submitter: Dr. Alex Mazin Submitte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PCBioAssay
LigandPNGBDBM50416564(CHEMBL1215813)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human RAD51 assessed as dissociation of protein/single-stranded DNA complex formation by fluorescence polarimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50416564(CHEMBL1215813)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human RAD51 assessed as dissociation of protein/single-stranded poly-(d-epsilonA) complex formation by fluorescence polarimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50184320(CHEMBL3823105)
Affinity DataIC50: 1.11E+4nMAssay Description:Inhibition of human N-terminal 6-histidine/Avi-tagged recombinant RAD51 expressed in Escherichia coli BL21(DE3) assessed as D-loop formation using 5'...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM32329(SMR000354813 | MLS001018610 | (2Z)-3-ethyl-2-[(E)-...)
Affinity DataIC50: 1.23E+4nMAssay Description:Project Title: A screen for modulators of human Rad51, a key DNA repair protein Application Number: MH084119 Assay Submitter: Dr. Alex Mazin Submitte...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
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