Compile Data Set for Download or QSAR
Report error Found 3127 of ic50 data for polymerid = 445,879,5527
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandPNGBDBM50617728(CHEMBL5415149)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandPNGBDBM50377072(CHEMBL438533)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of FMS mediated phosphorylation using SYEGNSYTFIDPTQ as substrate after 80 mins by fluorescence polarizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandPNGBDBM27912(8-(4-ethylphenyl)-N-methoxy-2-{[4-(1-methylpiperid...)
Affinity DataIC50: 0.300nMpH: 7.5 T: 2°CAssay Description:FMS was assayed using a fluorescence polarization (FP) competition immunoassay that measured FMS phosphorylation of FMS 555-568 peptide at Y561. The ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandPNGBDBM50377072(CHEMBL438533)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of FMSMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandPNGBDBM50321368(4-cyano-N-(4-(1,3-dimethyl-2-oxohexahydropyrimidin...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human FMS by fluorescence polarizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandPNGBDBM50617725(CHEMBL5404686)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandPNGBDBM50617731(CHEMBL5431583)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of CSF1R (530 to 910 residues) (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandPNGBDBM50622216(CHEMBL5434318)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of CSF1R (530 to 910 residues) (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandPNGBDBM50622217(CHEMBL5432649)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of CSF1R (530 to 910 residues) (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandPNGBDBM50622194(CHEMBL5439126)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of CSF1R (unknown origin) in presence of ATP by Z-LYTE based FRET assayMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandPNGBDBM50622195(CHEMBL5418087)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of CSF1R (unknown origin) in presence of ATP by Z-LYTE based FRET assayMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandPNGBDBM27909(8-(2,3-dihydro-1H-inden-5-yl)-N-methoxy-2-{[4-(1-m...)
Affinity DataIC50: 0.400nMpH: 7.5 T: 2°CAssay Description:FMS was assayed using a fluorescence polarization (FP) competition immunoassay that measured FMS phosphorylation of FMS 555-568 peptide at Y561. The ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandPNGBDBM27913(8-(3-ethylphenyl)-N-methoxy-2-{[4-(1-methylpiperid...)
Affinity DataIC50: 0.400nMpH: 7.5 T: 2°CAssay Description:FMS was assayed using a fluorescence polarization (FP) competition immunoassay that measured FMS phosphorylation of FMS 555-568 peptide at Y561. The ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandPNGBDBM27915(8-(4,4-dimethylcyclohexyl)-N-methoxy-2-{[4-(1-meth...)
Affinity DataIC50: 0.400nMpH: 7.5 T: 2°CAssay Description:FMS was assayed using a fluorescence polarization (FP) competition immunoassay that measured FMS phosphorylation of FMS 555-568 peptide at Y561. The ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandPNGBDBM50377071(CHEMBL402337)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of FMSMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandPNGBDBM50321373(4-cyano-N-(4-(2-(cyanoimino)-1,3-dimethylhexahydro...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human FMS by fluorescence polarizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandPNGBDBM50622203(CHEMBL5417607)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of CSF1R (530 to 910 residues) (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandPNGBDBM50622224(CHEMBL5425883)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of CSF1R (unknown origin) in presence of ATP by Z-LYTE based FRET assayMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandPNGBDBM50622229(CHEMBL5405206)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of CSF1R (unknown origin) in presence of ATP by Z-LYTE based FRET assayMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandPNGBDBM50622230(CHEMBL5430348)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of CSF1R (unknown origin) in presence of ATP by Z-LYTE based FRET assayMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandPNGBDBM50622232(CHEMBL5411617)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of CSF1R (unknown origin) in presence of ATP by Z-LYTE based FRET assayMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM98644(US8497376, 20)
Affinity DataIC50: 0.410nMpH: 7.5Assay Description:An autophosphorylation, fluroescence polarization competition immunoassay was used to determine the potency for c-fms inhibition.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM98627(US8497376, 8)
Affinity DataIC50: 0.420nMpH: 7.5Assay Description:An autophosphorylation, fluroescence polarization competition immunoassay was used to determine the potency for c-fms inhibition.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM238106(US9394289, 2)
Affinity DataIC50: 0.420nMpH: 7.5 T: 2°CAssay Description:An autophosphorylation, fluorescence polarization competition immunoassay was used to determine the potency for c-fms inhibition exhibited by selecte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandPNGBDBM669889(US20240132517, Example 1 | (S, 13E, 14E)-2-ethyl-4...)
Affinity DataIC50: 0.420nMAssay Description:The operation method is briefly described as follows:The powders of the compound were dissolved in 100% DMSO to make a 10 mM stock solution. The init...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM98621(US8497376, 2)
Affinity DataIC50: 0.430nMpH: 7.5Assay Description:An autophosphorylation, fluroescence polarization competition immunoassay was used to determine the potency for c-fms inhibition.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM119049(US8674100, 20 | CHEMBL3086320 | US8674100, 69)
Affinity DataIC50: 0.440nMpH: 7.5Assay Description:A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CSF-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM98624(US8497376, 5)
Affinity DataIC50: 0.470nMpH: 7.5Assay Description:An autophosphorylation, fluroescence polarization competition immunoassay was used to determine the potency for c-fms inhibition.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM238129(US9394289, 25)
Affinity DataIC50: 0.490nMpH: 7.5 T: 2°CAssay Description:An autophosphorylation, fluorescence polarization competition immunoassay was used to determine the potency for c-fms inhibition exhibited by selecte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandPNGBDBM27896(8-(2,3-dihydro-1H-inden-5-yl)-N-ethoxy-2-({4-[2-(4...)
Affinity DataIC50: 0.5nMpH: 7.5 T: 2°CAssay Description:FMS was assayed using a fluorescence polarization (FP) competition immunoassay that measured FMS phosphorylation of FMS 555-568 peptide at Y561. The ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandPNGBDBM27897(8-(2,3-dihydro-1H-inden-5-yl)-2-({4-[2-(4-methylpi...)
Affinity DataIC50: 0.5nMpH: 7.5 T: 2°CAssay Description:FMS was assayed using a fluorescence polarization (FP) competition immunoassay that measured FMS phosphorylation of FMS 555-568 peptide at Y561. The ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandPNGBDBM27906(8-(2,3-dihydro-1H-inden-5-yl)-N-methoxy-5-oxo-2-{[...)
Affinity DataIC50: 0.5nMpH: 7.5 T: 2°CAssay Description:FMS was assayed using a fluorescence polarization (FP) competition immunoassay that measured FMS phosphorylation of FMS 555-568 peptide at Y561. The ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM238109(US9394289, 5)
Affinity DataIC50: 0.5nMpH: 7.5 T: 2°CAssay Description:An autophosphorylation, fluorescence polarization competition immunoassay was used to determine the potency for c-fms inhibition exhibited by selecte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandPNGBDBM50321365(4-cyano-N-(2-cyclohexenyl-4-(1-methyl-2,6-dioxopip...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human FMS by fluorescence polarizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandPNGBDBM50321367(4-cyano-N-(2-cyclohexenyl-4-(1,3-dimethyl-2-oxohex...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human FMS by fluorescence polarizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandPNGBDBM50240209(CHEMBL4068526)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human CSF1R using poly[Glu:Tyr] (4:1) as substrate incubated for 2 hrs in presence of [33gammaP]ATP by P81 ion exchange chromatographic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandPNGBDBM50240227(CHEMBL4084391)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human CSF1R using poly[Glu:Tyr] (4:1) as substrate incubated for 2 hrs in presence of [33gammaP]ATP by P81 ion exchange chromatographic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandPNGBDBM50617720(CHEMBL5407395)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandPNGBDBM50622191(CHEMBL5406924)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of CSF1R (530 to 910 residues) (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandPNGBDBM50622215(CHEMBL5428404)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of CSF1R (530 to 910 residues) (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandPNGBDBM50622191(CHEMBL5406924)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of CSF1R (unknown origin) in presence of ATP by Z-LYTE based FRET assayMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM119049(US8674100, 20 | CHEMBL3086320 | US8674100, 69)
Affinity DataIC50: 0.510nMpH: 7.5Assay Description:A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CSF-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandPNGBDBM50579499(CHEMBL4847875)
Affinity DataIC50: 0.530nMAssay Description:Inhibition of wild-type human partial length CSF1R (I564 to S939 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandPNGBDBM595657(US11591328, Compound 10)
Affinity DataIC50: 0.550nMAssay Description:CSF1R: The specific operation is as follows: Set the concentration gradient of the test compound and dilute the test compound to the working concentr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM238121(US9394289, 17)
Affinity DataIC50: 0.560nMpH: 7.5 T: 2°CAssay Description:An autophosphorylation, fluorescence polarization competition immunoassay was used to determine the potency for c-fms inhibition exhibited by selecte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandPNGBDBM13216(N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyeth...)
Affinity DataIC50: 0.570nMAssay Description:Inhibition of CSF1R (unknown origin) by enzymatic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM119032(US8674100, 45)
Affinity DataIC50: 0.600nMpH: 7.5Assay Description:A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CSF-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandPNGBDBM50233716(5-cyano-N-(4-(4-(2-hydroxyethyl)piperazin-1-yl)-2-...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human cytoplasmic FMS expressed in Sf9-baculovirus system after 80 mins by fluorescence polarizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandPNGBDBM50443154(CHEMBL3085973 | US8674100, 147)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of FMS (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandPNGBDBM119049(US8674100, 20 | CHEMBL3086320 | US8674100, 69)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of FMS (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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