Compile Data Set for Download or QSAR
Report error Found 25 of ic50 data for polymerid = 4431,50004314,50007694
TargetGag polyprotein(HIV-1)
Dupont Pharmaceuticals

LigandPNGBDBM36656(Cyclobutylmethyl cyclic urea)
Affinity DataIC50: 7.80nMpH: 6.5Assay Description:Enzyme inhibition assay using cyclic ureas to inhibit GAG polyprotein.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGag polyprotein(HIV-1)
Dupont Pharmaceuticals

LigandPNGBDBM36657(2-Naphthylmethyl cyclic urea)
Affinity DataIC50: 12nMpH: 6.5Assay Description:Enzyme inhibition assay using cyclic ureas to inhibit GAG polyprotein.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGag polyprotein(HIV-1)
Dupont Pharmaceuticals

LigandPNGBDBM577(VX-478 | 141W94 | APV | BDBM50215393 | CHEMBL116 |...)
Affinity DataIC50: 13nMpH: 6.5Assay Description:Enzyme inhibition assay using cyclic ureas to inhibit GAG polyprotein.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag polyprotein(HIV-1)
Dupont Pharmaceuticals

LigandPNGBDBM519(SQV | Invirase | CHEMBL114 | Ro 31-8959 | Fortovas...)
Affinity DataIC50: 13.1nMpH: 6.5Assay Description:Enzyme inhibition assay using cyclic ureas to inhibit GAG polyprotein.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag polyprotein(HIV-1)
Dupont Pharmaceuticals

LigandPNGBDBM517(Crixivan | CHEMBL115 | L-735, 524 | MK639 | Indina...)
Affinity DataIC50: 20nMpH: 6.5Assay Description:Enzyme inhibition assay using cyclic ureas to inhibit GAG polyprotein.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag polyprotein(HIV-1)
Dupont Pharmaceuticals

LigandPNGBDBM36655(Cyclopropylmethyl cyclic urea)
Affinity DataIC50: 25nMpH: 6.5Assay Description:Enzyme inhibition assay using cyclic ureas to inhibit GAG polyprotein.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGag polyprotein(HIV-1)
Dupont Pharmaceuticals

LigandPNGBDBM50124714((4R,5S,6S,7R)-1-(3-Amino-1H-indazol-5-ylmethyl)-4,...)
Affinity DataIC50: 39.5nMpH: 6.5Assay Description:Enzyme inhibition assay using cyclic ureas to inhibit GAG polyprotein.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag polyprotein(HIV-1)
Dupont Pharmaceuticals

LigandPNGBDBM36658(n-Pentyl cyclic urea)
Affinity DataIC50: 41nMpH: 6.5Assay Description:Enzyme inhibition assay using cyclic ureas to inhibit GAG polyprotein.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGag polyprotein(HIV-1)
Dupont Pharmaceuticals

LigandPNGBDBM36646(DMP850)
Affinity DataIC50: 49nMpH: 6.5Assay Description:Enzyme inhibition assay using cyclic ureas to inhibit GAG polyprotein.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGag polyprotein(HIV-1)
Dupont Pharmaceuticals

LigandPNGBDBM36659(n-Hexyl cyclic urea)
Affinity DataIC50: 130nMpH: 6.5Assay Description:Enzyme inhibition assay using cyclic ureas to inhibit GAG polyprotein.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGag polyprotein(Avian erythroblastosis virus (strain ES4))
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50273882(2-[3-chloro-3-phenylprop-2-enylidene]hydrazinecarb...)
Affinity DataIC50: 900nMAssay Description:Antagonist activity at estrogen receptor alpha expressed in human HEC1 cells assessed as inhibition of 1 nM estradiol-induced transcriptional activit...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag polyprotein(Avian erythroblastosis virus (strain ES4))
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50273849(1-Chloro-5,7-dimethyl-3,4-dihydronaphthalene-2-car...)
Affinity DataIC50: 1.20E+3nMAssay Description:Antagonist activity at estrogen receptor alpha expressed in human HEC1 cells assessed as inhibition of 1 nM estradiol-induced transcriptional activit...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag polyprotein(Avian erythroblastosis virus (strain ES4))
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50273851(2-[(3-chloro-1H-inden-2-yl)methylene]hydrazinecarb...)
Affinity DataIC50: 1.30E+3nMAssay Description:Antagonist activity at estrogen receptor alpha expressed in human HEC1 cells assessed as inhibition of 1 nM estradiol-induced transcriptional activit...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag polyprotein(Avian erythroblastosis virus (strain ES4))
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50273883(beta-Chloro-alpha-methylcinnamaldehyde guanylhydra...)
Affinity DataIC50: 1.40E+3nMAssay Description:Antagonist activity at estrogen receptor alpha expressed in human HEC1 cells assessed as inhibition of 1 nM estradiol-induced transcriptional activit...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag polyprotein(Avian erythroblastosis virus (strain ES4))
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50253469(2-[(1-chloro-3,4-dihydronaphthalen-2-yl)methylene]...)
Affinity DataIC50: 1.40E+3nMAssay Description:Antagonist activity at estrogen receptor alpha expressed in human HEC1 cells assessed as inhibition of 1 nM estradiol-induced transcriptional activit...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag polyprotein(Avian erythroblastosis virus (strain ES4))
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50273850(1-Chloro-3-dihydro-4-methylnaphthalene-2-carboxald...)
Affinity DataIC50: 1.50E+3nMAssay Description:Antagonist activity at estrogen receptor alpha expressed in human HEC1 cells assessed as inhibition of 1 nM estradiol-induced transcriptional activit...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag polyprotein(Avian erythroblastosis virus (strain ES4))
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50273848(1-Chloro-6-methoxy-3,4-dihydronaphthalene-2-carbox...)
Affinity DataIC50: 2.00E+3nMAssay Description:Antagonist activity at estrogen receptor alpha expressed in human HEC1 cells assessed as inhibition of 1 nM estradiol-induced transcriptional activit...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag polyprotein(Avian erythroblastosis virus (strain ES4))
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50273854(1-Methoxy-3,4-dihydronaphthalene-2-carboxaldehyde ...)
Affinity DataIC50: 3.10E+3nMAssay Description:Antagonist activity at estrogen receptor alpha expressed in human HEC1 cells assessed as inhibition of 1 nM estradiol-induced transcriptional activit...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag polyprotein(Avian erythroblastosis virus (strain ES4))
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50273852(9-Chloro-6,7-dihydro-5-benzocycloheptene-8-carboxa...)
Affinity DataIC50: 3.30E+3nMAssay Description:Antagonist activity at estrogen receptor alpha expressed in human HEC1 cells assessed as inhibition of 1 nM estradiol-induced transcriptional activit...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag polyprotein(Avian erythroblastosis virus (strain ES4))
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50273880(1-Phenoxy-3,4-dihydronaphthalene-2-carboxaldehyde ...)
Affinity DataIC50: 3.50E+3nMAssay Description:Antagonist activity at estrogen receptor alpha expressed in human HEC1 cells assessed as inhibition of 1 nM estradiol-induced transcriptional activit...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag polyprotein(Avian erythroblastosis virus (strain ES4))
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50273847(1-Chloro-7-methoxy-3,4-dihydronaphthalene-2-carbox...)
Affinity DataIC50: 3.90E+3nMAssay Description:Antagonist activity at estrogen receptor alpha expressed in human HEC1 cells assessed as inhibition of 1 nM estradiol-induced transcriptional activit...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag polyprotein(Avian erythroblastosis virus (strain ES4))
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50240439(2-(1-Naphthalenylmethylene) hydrazinecarboximidami...)
Affinity DataIC50: 7.50E+3nMAssay Description:Antagonist activity at estrogen receptor alpha expressed in human HEC1 cells assessed as inhibition of 1 nM estradiol-induced transcriptional activit...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag polyprotein(Avian erythroblastosis virus (strain ES4))
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50240438(N''-[(1E)-2-naphthylmethylene]carbonohydrazonic di...)
Affinity DataIC50: 7.50E+3nMAssay Description:Antagonist activity at estrogen receptor alpha expressed in human HEC1 cells assessed as inhibition of 1 nM estradiol-induced transcriptional activit...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag polyprotein(Avian erythroblastosis virus (strain ES4))
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50273853(1-Bromo-3,4-dihydronaphthalene-2-carboxaldehyde gu...)
Affinity DataIC50: 7.80E+3nMAssay Description:Antagonist activity at estrogen receptor alpha expressed in human HEC1 cells assessed as inhibition of 1 nM estradiol-induced transcriptional activit...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag polyprotein(Avian erythroblastosis virus (strain ES4))
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50273881(1-(1,1,1,-Trifluoromethyl)-3,4-dihydronaphthalene-...)
Affinity DataIC50: 1.20E+4nMAssay Description:Antagonist activity at estrogen receptor alpha expressed in human HEC1 cells assessed as inhibition of 1 nM estradiol-induced transcriptional activit...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed