Compile Data Set for Download or QSAR
Report error Found 76 of ic50 data for polymerid = 381
TargetBromodomain-containing protein 3 [51-123](Human)
Aptose Biosciences

US Patent
LigandPNGBDBM543479(US11279703, Table 1.2 | US11279703, TABLE 6.320 | ...)
Affinity DataIC50: 49nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
Aptose Biosciences

US Patent
LigandPNGBDBM543481(US11279703, Table 1.4 | US11279703, TABLE 6.353 | ...)
Affinity DataIC50: 59nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
Aptose Biosciences

US Patent
LigandPNGBDBM543677(US11279703, TABLE 6.266)
Affinity DataIC50: 78nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
Aptose Biosciences

US Patent
LigandPNGBDBM50365262(CHEMBL1957266 | (S)-JQ1 (1) | US9320741, (S)-JQ1 |...)
Affinity DataIC50: 80nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
Aptose Biosciences

US Patent
LigandPNGBDBM205429( (R)-JQ1 (3) | US9320741, (R)-JQ1 | US10407441, Co...)
Affinity DataIC50: 81nMAssay Description:Determine the binding ability of BRD4 compounds to bromodomains of BRD2 and BRD4. 96 well plate based commercial TR-FRET Assay kits (Cayman Chemical,...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
Aptose Biosciences

US Patent
LigandPNGBDBM543776(US11279703, TABLE 6.388 | US11279703, TABLE 6.366)
Affinity DataIC50: 81nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
Aptose Biosciences

US Patent
LigandPNGBDBM543776(US11279703, TABLE 6.388 | US11279703, TABLE 6.366)
Affinity DataIC50: 83nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
Aptose Biosciences

US Patent
LigandPNGBDBM543638(US11279703, TABLE 6.227)
Affinity DataIC50: 89nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
Aptose Biosciences

US Patent
LigandPNGBDBM543570(US11279703, TABLE 6.159 | US11643396, Example SG4-...)
Affinity DataIC50: 92nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
Aptose Biosciences

US Patent
LigandPNGBDBM543789(US11279703, TABLE 6.379 | US11279703, TABLE 6.380)
Affinity DataIC50: 97nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
Aptose Biosciences

US Patent
LigandPNGBDBM313773(US10167292, Example 7)
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
Aptose Biosciences

US Patent
LigandPNGBDBM543797(US11279703, TABLE 6.387)
Affinity DataIC50: 100nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
Aptose Biosciences

US Patent
LigandPNGBDBM313796(US10167292, Example 40)
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
Aptose Biosciences

US Patent
LigandPNGBDBM313795(US10167292, Example 39)
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
Aptose Biosciences

US Patent
LigandPNGBDBM313794(US10167292, Example 38)
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
Aptose Biosciences

US Patent
LigandPNGBDBM313793(US10167292, Example 37)
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
Aptose Biosciences

US Patent
LigandPNGBDBM313792(US10167292, Example 36)
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
Aptose Biosciences

US Patent
LigandPNGBDBM313791(US10167292, Example 35)
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
Aptose Biosciences

US Patent
LigandPNGBDBM313789(US10167292, Example 33)
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
Aptose Biosciences

US Patent
LigandPNGBDBM313771(US10167292, Example 5)
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
Aptose Biosciences

US Patent
LigandPNGBDBM313774(US10167292, Example 8)
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
Aptose Biosciences

US Patent
LigandPNGBDBM313775(US10167292, Example 10)
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
Aptose Biosciences

US Patent
LigandPNGBDBM313776(US10167292, Example 11)
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
Aptose Biosciences

US Patent
LigandPNGBDBM313777(US10167292, Example 12)
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
Aptose Biosciences

US Patent
LigandPNGBDBM313778(US10167292, Example 13)
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
Aptose Biosciences

US Patent
LigandPNGBDBM313779(US10167292, Example 16)
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
Aptose Biosciences

US Patent
LigandPNGBDBM313780(US10167292, Example 20)
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
Aptose Biosciences

US Patent
LigandPNGBDBM313781(US10167292, Example 21)
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
Aptose Biosciences

US Patent
LigandPNGBDBM313782(US10167292, Example 22)
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
Aptose Biosciences

US Patent
LigandPNGBDBM313790(US10167292, Example 34)
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
Aptose Biosciences

US Patent
LigandPNGBDBM313788(US10167292, Example 32)
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
Aptose Biosciences

US Patent
LigandPNGBDBM313787(US10167292, Example 31)
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
Aptose Biosciences

US Patent
LigandPNGBDBM313784(US10167292, Example 24)
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
Aptose Biosciences

US Patent
LigandPNGBDBM313783(US10167292, Example 23)
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
Aptose Biosciences

US Patent
LigandPNGBDBM543629(US11279703, TABLE 6.218 | US11279703, TABLE 6.263)
Affinity DataIC50: 109nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
Aptose Biosciences

US Patent
LigandPNGBDBM543757(US11279703, TABLE 6.347)
Affinity DataIC50: 110nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
Aptose Biosciences

US Patent
LigandPNGBDBM543701(US11279703, TABLE 6.290)
Affinity DataIC50: 117nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
Aptose Biosciences

US Patent
LigandPNGBDBM543682(US11279703, TABLE 6.271)
Affinity DataIC50: 117nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
Aptose Biosciences

US Patent
LigandPNGBDBM543795(US11279703, TABLE 6.386 | US11279703, TABLE 6.385)
Affinity DataIC50: 123nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
Aptose Biosciences

US Patent
LigandPNGBDBM543684(US11279703, TABLE 6.273)
Affinity DataIC50: 142nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
Aptose Biosciences

US Patent
LigandPNGBDBM543791(US11279703, TABLE 6.381 | US11279703, TABLE 6.382)
Affinity DataIC50: 154nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
Aptose Biosciences

US Patent
LigandPNGBDBM543795(US11279703, TABLE 6.386 | US11279703, TABLE 6.385)
Affinity DataIC50: 158nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
Aptose Biosciences

US Patent
LigandPNGBDBM543649(US11279703, TABLE 6.238)
Affinity DataIC50: 161nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
Aptose Biosciences

US Patent
LigandPNGBDBM543505(US11279703, TABLE 5.3 | US11279703, TABLE 6.240 | ...)
Affinity DataIC50: 164nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
Aptose Biosciences

US Patent
LigandPNGBDBM543756(US11279703, TABLE 6.346)
Affinity DataIC50: 181nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
Aptose Biosciences

US Patent
LigandPNGBDBM543569(US11279703, TABLE 6.158 | US11279703, TABLE 6.169 ...)
Affinity DataIC50: 183nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
Aptose Biosciences

US Patent
LigandPNGBDBM543758(US11279703, TABLE 6.348)
Affinity DataIC50: 196nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
Aptose Biosciences

US Patent
LigandPNGBDBM543516(US11279703, TABLE 6.37 | US11279703, TABLE 6.199 |...)
Affinity DataIC50: 213nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails
US Patent
PDB3D3D Structure (crystal)
TargetBromodomain-containing protein 3 [51-123](Human)
Aptose Biosciences

US Patent
LigandPNGBDBM543652(US11279703, TABLE 6.241)
Affinity DataIC50: 248nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
Aptose Biosciences

US Patent
LigandPNGBDBM543480(US11279703, Table 1.3 | US11279703, TABLE 6.74 | U...)
Affinity DataIC50: 248nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

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