Compile Data Set for Download or QSAR
Report error Found 309 of ic50 data for polymerid = 2762
LigandPNGBDBM444320(US10660898, Example 70)
Affinity DataIC50: 0.200nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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US Patent

LigandPNGBDBM444306(US10660898, Example 25)
Affinity DataIC50: 0.251nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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US Patent

LigandPNGBDBM444315(US10660898, Example 53)
Affinity DataIC50: 0.501nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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US Patent

LigandPNGBDBM444311(US10660898, Example 39)
Affinity DataIC50: 0.631nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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US Patent

LigandPNGBDBM50579668(CHEMBL5091438)
Affinity DataIC50: 0.794nMAssay Description:Inhibition of PIK3C2B (unknown origin) assessed as reduction in substrate phosphorylation by FRET Adapta assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM444301(US10660898, Example 15)
Affinity DataIC50: 1nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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US Patent

LigandPNGBDBM444319(US10660898, Example 63)
Affinity DataIC50: 1nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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US Patent

LigandPNGBDBM489258(US10961236, Example 31 | 2-[(1S)-1-Cyclopropylethy...)
Affinity DataIC50: 1nMAssay Description:Inhibition of PIK3C2B (unknown origin) assessed as reduction in substrate phosphorylation by FRET Adapta assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM444314(US10660898, Example 50)
Affinity DataIC50: 1.26nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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US Patent

LigandPNGBDBM444297(US10660898, Example 5)
Affinity DataIC50: 1.58nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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US Patent

LigandPNGBDBM444312(US10660898, Example 41)
Affinity DataIC50: 1.58nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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US Patent

LigandPNGBDBM444321(US10660898, Example 72)
Affinity DataIC50: 1.58nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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US Patent

LigandPNGBDBM444298(US10660898, Example 11)
Affinity DataIC50: 2nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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US Patent

LigandPNGBDBM444302(US10660898, Example 17)
Affinity DataIC50: 2.51nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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US Patent

LigandPNGBDBM444316(US10660898, Example 54)
Affinity DataIC50: 2.51nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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US Patent

LigandPNGBDBM444300(US10660898, Example 14)
Affinity DataIC50: 3.16nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM50512861(CHEMBL4558527)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of PIK3C2B (unknown origin) assessed as reduction in substrate phosphorylation by FRET Adapta assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM444313(US10660898, Example 43)
Affinity DataIC50: 5.01nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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US Patent

LigandPNGBDBM444304(US10660898, Example 20)
Affinity DataIC50: 6.31nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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US Patent

LigandPNGBDBM50059637(GSK-2636771 | GSK2636771 | US10660898, Example 31)
Affinity DataIC50: 6.31nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM444317(US10660898, Example 58)
Affinity DataIC50: 6.31nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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US Patent

LigandPNGBDBM444318(US10660898, Example 59)
Affinity DataIC50: 6.31nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM444299(US10660898, Example 13)
Affinity DataIC50: 7.94nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM25045(CHEMBL538346 | mTOR Inhibitor, PI103 | PI-103 | 3-...)
Affinity DataIC50: 10nMpH: 7.4 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM25045(CHEMBL538346 | mTOR Inhibitor, PI103 | PI-103 | 3-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of PI3Kc2betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM444303(US10660898, Example 18)
Affinity DataIC50: 10nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM444308(US10660898, Example 32)
Affinity DataIC50: 12.6nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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US Patent

LigandPNGBDBM444305(US10660898, Example 22)
Affinity DataIC50: 15.8nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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US Patent

LigandPNGBDBM50341209(9-(6-aminopyridin-3-yl)-1-(3-(trifluoromethyl)phen...)
Affinity DataIC50: 25nMAssay Description:Inhibition of PI3K-C2betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM444322(US10660898, Example 73)
Affinity DataIC50: 25.1nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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US Patent

LigandPNGBDBM25045(CHEMBL538346 | mTOR Inhibitor, PI103 | PI-103 | 3-...)
Affinity DataIC50: 26nMAssay Description:Inhibition of human PI3KC2beta by non-radiometric ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50197065(CHEMBL3913354)
Affinity DataIC50: 26nMAssay Description:Inhibition of PI3KC2beta (unknown origin) expressed in HEK293 cells using phosphatidylinositol and gamma-32P-ATP incubated for 20 mins by TLC assay o...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50394846(CHEMBL2165017 | US8772480, 35)
Affinity DataIC50: 29nMAssay Description:Inhibition of PIK3C2betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50274638(CHEMBL4126156 | US10858355, Example 4)
Affinity DataIC50: 32nMAssay Description:Inhibition of PI3KC2beta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50630157(CHEMBL5405102)
Affinity DataIC50: 43nMAssay Description:Inhibition of N-terminal 6His-tagged PI3KC2beta (unknown origin) expressed in Escherichia coli DH10 infected in Sf21 insect cells incubated for 60 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
LigandPNGBDBM50042923(CHEMBL3354566)
Affinity DataIC50: 44nMAssay Description:Inhibition of human PI3KC2beta by non-radiometric ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM92862(mTOR Inhibitor, BEZ235 | US9284315, BEZ-235)
Affinity DataIC50: 44nMAssay Description:Inhibition of human recombinant PI3KC2beta using substrate PI incubated for 1 hr by Adapta kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM444309(US10660898, Example 35)
Affinity DataIC50: 63.1nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM81368(PIK90)
Affinity DataIC50: 64nMAssay Description:Inhibition of human PI3KC2beta by non-radiometric ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM81368(PIK90)
Affinity DataIC50: 64nMAssay Description:Inhibition of PI3KC2beta (unknown origin) expressed in HEK293 cells using phosphatidylinositol and gamma-32P-ATP incubated for 20 mins by TLC assay o...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM25036(CHEMBL393525 | N'-[(1E)-{6-bromoimidazo[1,2-a]pyri...)
Affinity DataIC50: 100nMpH: 7.4 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM25056(4-{6-chloroimidazo[1,2-a]pyridin-3-yl}-2-[(2-methy...)
Affinity DataIC50: 100nMpH: 7.4 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM348119(US9790228, Compound 38)
Affinity DataIC50: 100nMAssay Description:Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM348131(US9790228, Compound 197 | US9790228, Compound 50)
Affinity DataIC50: 100nMAssay Description:Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM50323731(N-(6-(4-amino-1-((2-(4-methylpiperazin-1-yl)quinol...)
Affinity DataIC50: 100nMAssay Description:Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM348154(US9790228, Compound 73)
Affinity DataIC50: 100nMAssay Description:Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM348161(US9790228, Compound 80)
Affinity DataIC50: 100nMAssay Description:Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM348211(US9790228, Compound 130)
Affinity DataIC50: 100nMAssay Description:Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM348220(US9790228, Compound 139)
Affinity DataIC50: 100nMAssay Description:Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM348244(US9790228, Compound 163)
Affinity DataIC50: 100nMAssay Description:Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

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