Compile Data Set for Download or QSAR
Report error Found 699 of ic50 data for polymerid = 2538,50001019,50007284
TargetPolyamine deacetylase HDAC10(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50101331(CHEMBL3329621)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of HDAC10 (unknown origin) incubated for 30 mins in presence of BSA and DTT by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50105327(JNJ-26481585 | Quisinostat)
Affinity DataIC50: 0.460nMAssay Description:Inhibition of HDAC10 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50020912(Largazole Thiol)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of HDAC10 (unknown origin) incubated for 30 mins in presence of BSA and in absence of DTT by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50101330(CHEMBL3329622)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of HDAC10 (unknown origin) incubated for 30 mins in presence of BSA and DTT by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50098414(CHEMBL3593247)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of N-terminal GST-tagged/C-terminal His-tagged human HDAC10 (1 to 481 residues) expressed in baculovirus infected Sf9 insect cells using B...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50105327(JNJ-26481585 | Quisinostat)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of HDAC10 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50530002(CHEMBL4532398)
Affinity DataIC50: 0.580nMAssay Description:Inhibition of recombinant full length N-terminal FLAG-tagged human HDAC10 expressed in baculovirus infected sf9 cells using Ac-peptide-AMC as substra...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50530002(CHEMBL4532398)
Affinity DataIC50: 0.580nMAssay Description:Inhibition of recombinant full length N-terminal FLAG-tagged human HDAC10 expressed in baculovirus infected sf9 cells using Ac-peptide-AMC as substra...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50188899(CHEMBL3827517)
Affinity DataIC50: 0.860nMAssay Description:Inhibition of human recombinant HDAC10 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC as substrate assessed as release of AM...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50354086(FK-228 | Istodax | ROMIDEPSIN)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of HDAC10 (unknown origin) incubated for 30 mins in presence of BSA and DTT by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50027494(CHEMBL3356916)
Affinity DataIC50: 1nMAssay Description:Inhibition of HDAC10 (unknown origin) using fluorogenic tetrapeptide RHKK(Ac) substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50048864(CHEMBL3310505)
Affinity DataIC50: 1nMAssay Description:Inhibition of HDAC10 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50005711(GNF-Pf-1011 | CHEBI:46024 | TRICHOSTATIN | Trichos...)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant full-length human HDAC10 using FITC-H3K27(Ac)-NH2 as substrate by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50530003(CHEMBL4552057)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of recombinant full length N-terminal FLAG-tagged human HDAC10 expressed in baculovirus infected sf9 cells using Ac-peptide-AMC as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50530003(CHEMBL4552057)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of recombinant full length N-terminal FLAG-tagged human HDAC10 expressed in baculovirus infected sf9 cells using Ac-peptide-AMC as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPolyamine deacetylase HDAC10(Mouse)
S£O Paulo State University (Unesp)

Curated by ChEMBL
LigandPNGBDBM50531479(CHEMBL4439518)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of mouse liver HDAC using Boc-Lys (Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50005711(GNF-Pf-1011 | CHEBI:46024 | TRICHOSTATIN | Trichos...)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of recombinant full length human HDAC10 expressed in baculovirus infected Sf9 cells using FAM-RHKK-Ac as substrate incubated for 17 hrs by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50555460(CHEMBL4785064)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of N-terminal FLAG-tagged human HDAC10 (2 to 631 residues) expressed in baculovirus infected Sf9 cells using fluorogenic HDAC substrate 3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50027519(CHEMBL3356924)
Affinity DataIC50: 2nMAssay Description:Inhibition of HDAC10 (unknown origin) using fluorogenic tetrapeptide RHKK(Ac) substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50514463(CHEMBL4460552)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human His6/GST-tagged HDAC10 expressed in baculovirus infected High5 insect cells using Ac-Lys-Tyr-Lys(epsilon-acetyl)-AMC ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50105327(JNJ-26481585 | Quisinostat)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant full length human HDAC10 expressed in baculovirus infected Sf9 cells using FAM-RHKK-Ac as substrate incubated for 17 hrs by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50105327(JNJ-26481585 | Quisinostat)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant full length human HDAC10 expressed in SF9 baculovirus using FAM- labelled acetylated peptide as substrate measured by Elect...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM323709(US10188756, Compound CN133 | US11207431, Martinost...)
Affinity DataIC50: 2nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPolyamine deacetylase HDAC10(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM29589(Panobinostat | Faridak | LBH-589B | LBH-589 | US10...)
Affinity DataIC50: 2nMAssay Description:Inhibition of HDAC10 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM29589(Panobinostat | Faridak | LBH-589B | LBH-589 | US10...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of HDAC10 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50526161(CHEMBL4464421)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of HDAC10 (unknown origin) using (FAM)-labeled acetylated peptide as substrate measured after 17 hrs by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50555464(CHEMBL4744689)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of N-terminal FLAG-tagged human HDAC10 (2 to 631 residues) expressed in baculovirus infected Sf9 cells using fluorogenic HDAC substrate 3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM29589(Panobinostat | Faridak | LBH-589B | LBH-589 | US10...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human recombinant HDAC10 using Boc-Lys(triflouroacetyI)-AMC substrate incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50555461(CHEMBL4749655)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of N-terminal FLAG-tagged human HDAC10 (2 to 631 residues) expressed in baculovirus infected Sf9 cells using fluorogenic HDAC substrate 3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50188959(CHEMBL3827894)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human recombinant HDAC10 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC as substrate assessed as release of AM...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50188961(CHEMBL3622533)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human recombinant HDAC10 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC as substrate assessed as release of AM...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50188637(CHEMBL3827814)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human recombinant HDAC10 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC as substrate assessed as release of AM...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50188961(CHEMBL3622533)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of HDAC10 (unknown origin) using Color de lys as substrate by HTS assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50188961(CHEMBL3622533)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of HDAC10 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50188961(CHEMBL3622533)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of HDAC10 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50105327(JNJ-26481585 | Quisinostat)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of full-length HDAC10 (unknown origin) by Color-de-Lys assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50405632(CHEMBL5278968)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human HDAC10 by fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50188961(CHEMBL3622533)
Affinity DataIC50: 3nMAssay Description:Inhibition of HDAC10 (unknown origin) by color de Lys colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50242139(CHEMBL4078721)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of N-terminal GST-tagged/C-terminal His-tagged human HDAC10 (1 to 481 residues) expressed in baculovirus infected Sf9 insect cells using B...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50582354(CHEMBL5076728)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of recombinant HDAC10 (unknown origin) using Ac-peptide-AMC as substrate incubated for 240 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50526156(CHEMBL1630208 | WR301861)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of HDAC10 (unknown origin) using (FAM)-labeled acetylated peptide as substrate measured after 17 hrs by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50123617(CHEMBL3622726)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of recombinant human HDAC10 after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50027495(CHEMBL3356917)
Affinity DataIC50: 4nMAssay Description:Inhibition of HDAC10 (unknown origin) using fluorogenic tetrapeptide RHKK(Ac) substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50027501(CHEMBL3356923)
Affinity DataIC50: 4nMAssay Description:Inhibition of HDAC10 (unknown origin) using fluorogenic tetrapeptide RHKK(Ac) substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM29589(Panobinostat | Faridak | LBH-589B | LBH-589 | US10...)
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant HDAC10 (unknown origin) using AMC labeled AC-peptide as substrate incubated for 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50521588(CHEMBL4578278)
Affinity DataIC50: 4nMAssay Description:Inhibition of dye-labeled tracer binding to HDAC10 (unknown origin) transfected in human HeLa cells measured after 2 hrs by nano-luciferase reporter ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50521588(CHEMBL4578278)
Affinity DataIC50: 4nMAssay Description:Inhibition of tubastatin-Alexa647-tracer binding to recombinant GST-tagged HDAC10 (unknown origin) measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50232354(CHEMBL4066920)
Affinity DataIC50: 4nMAssay Description:Inhibition of dye-labeled tracer binding to HDAC10 (unknown origin) transfected in human HeLa cells measured after 2 hrs by nano-luciferase reporter ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM24622(3-[(dimethylamino)methyl]-N-{2-[4-(hydroxycarbamoy...)
Affinity DataIC50: 4nMAssay Description:Inhibition of tubastatin-Alexa647-tracer binding to recombinant GST-tagged HDAC10 (unknown origin) measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50188961(CHEMBL3622533)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of N-terminal FLAG-tagged human HDAC10 (2 to 631 residues) expressed in baculovirus infected Sf9 cells using fluorogenic HDAC substrate 3 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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