Compile Data Set for Download or QSAR
Report error Found 363 of ic50 data for polymerid = 241,2248,2250,4362
TargetLegumain(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50626215(CHEMBL5413711)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human 8His tagged AEP using Z-Ala-Ala-Asn-Rhl 10-(D-Pro) as fluorogenic substrate incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetLegumain(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50626216(CHEMBL5420042)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human 8His tagged AEP using Z-Ala-Ala-Asn-Rhl 10-(D-Pro) as fluorogenic substrate incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetLegumain(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50510337(CHEMBL4545652)
Affinity DataIC50: 0.120nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC as substrate measured for every 2 mins for 60 mins by fluorescence-based microplate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLegumain(Common tick)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50378274(CHEMBL573437)
Affinity DataIC50: 0.140nMAssay Description:Inhibition of Ixodes ricinus asparaginyl endopeptidasesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLegumain(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50631580(CHEMBL5427662)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant AEP (unknown origin) using Z0AAn-Rh110 as peptide substrate measured for 15 to 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetLegumain(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50629127(CHEMBL5412556)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant AEP (unknown origin) using Z0AAn-Rh110 as peptide substrate measured for 15 to 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetLegumain(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50626218(CHEMBL5402155)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant AEP (unknown origin) using Z0AAn-Rh110 as peptide substrate measured for 15 to 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetLegumain(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50626213(CHEMBL5425743)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human 8His tagged AEP using Z-Ala-Ala-Asn-Rhl 10-(D-Pro) as fluorogenic substrate incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetLegumain(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50626214(CHEMBL5394077)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human 8His tagged AEP using Z-Ala-Ala-Asn-Rhl 10-(D-Pro) as fluorogenic substrate incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetLegumain(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50626217(CHEMBL5402221)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human 8His tagged AEP using Z-Ala-Ala-Asn-Rhl 10-(D-Pro) as fluorogenic substrate incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetLegumain(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50626218(CHEMBL5402155)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human 8His tagged AEP using Z-Ala-Ala-Asn-Rhl 10-(D-Pro) as fluorogenic substrate incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetLegumain(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50629127(CHEMBL5412556)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human 8His-tagged AEP (V18 to Y433 residues) using Z-Ala-Ala-Asn-Rhl 10-(D-Pro) as substrate incubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetLegumain(Common tick)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50378260(CHEMBL577594)
Affinity DataIC50: 0.230nMAssay Description:Inhibition of Ixodes ricinus asparaginyl endopeptidasesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLegumain(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50510318(CHEMBL4438891)
Affinity DataIC50: 0.260nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC as substrate measured for every 2 mins for 60 mins by fluorescence-based microplate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLegumain(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50631598(CHEMBL5415768)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of recombinant AEP (unknown origin) using Z0AAn-Rh110 as peptide substrate measured for 15 to 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetLegumain(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50629126(CHEMBL5418321)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human 8His-tagged AEP (V18 to Y433 residues) using Z-Ala-Ala-Asn-Rhl 10-(D-Pro) as substrate incubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetLegumain(Common tick)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50378275(CHEMBL582897)
Affinity DataIC50: 0.350nMAssay Description:Inhibition of Ixodes ricinus asparaginyl endopeptidasesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLegumain(Common tick)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50378276(CHEMBL582898)
Affinity DataIC50: 0.370nMAssay Description:Inhibition of Ixodes ricinus asparaginyl endopeptidasesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLegumain(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50631610(CHEMBL5417499)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of recombinant AEP (unknown origin) using Z0AAn-Rh110 as peptide substrate measured for 15 to 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetLegumain(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50510331(CHEMBL4556228)
Affinity DataIC50: 0.470nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC as substrate measured for every 2 mins for 60 mins by fluorescence-based microplate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLegumain(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50631579(CHEMBL5399304)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant AEP (unknown origin) using Z0AAn-Rh110 as peptide substrate measured for 15 to 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetLegumain(Common tick)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50378280(CHEMBL576557)
Affinity DataIC50: 0.520nMAssay Description:Inhibition of Ixodes ricinus asparaginyl endopeptidasesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLegumain(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50631604(CHEMBL5419921)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant AEP (unknown origin) using Z0AAn-Rh110 as peptide substrate measured for 15 to 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetLegumain(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50631578(CHEMBL5406157)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of recombinant AEP (unknown origin) using Z0AAn-Rh110 as peptide substrate measured for 15 to 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetLegumain(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50631602(CHEMBL5409889)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of recombinant AEP (unknown origin) using Z0AAn-Rh110 as peptide substrate measured for 15 to 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetLegumain(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50631578(CHEMBL5406157)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of AEP (unknown origin) expressed in HEK293-A cells using fluorogenic substrate assessed as fluorescence emission intensity preincubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetLegumain(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50015362(CHEMBL3264590)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLegumain(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50631590(CHEMBL5407269)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of recombinant AEP (unknown origin) using Z0AAn-Rh110 as peptide substrate measured for 15 to 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetLegumain(Common tick)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM22116(benzyl (2E)-3-{N'-[(2S)-2-[(2S)-2-{[(benzyloxy)car...)
Affinity DataIC50: 1nMT: 2°CAssay Description:AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLegumain(Common tick)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM22125(benzyl N-[(1S)-1-{[(2S)-1-[(2E)-N-benzyl-3-[N-(car...)
Affinity DataIC50: 1nMT: 2°CAssay Description:AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLegumain(Common tick)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM22128(benzyl N-[(1S)-1-{[(2S)-1-[(2E)-N-benzyl-3-[N-(car...)
Affinity DataIC50: 1nMT: 2°CAssay Description:AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLegumain(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50629122(CHEMBL5427707)
Affinity DataIC50: 1nMAssay Description:Inhibition of human 8His-tagged AEP (V18 to Y433 residues) using Z-Ala-Ala-Asn-Rhl 10-(D-Pro) as substrate incubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetLegumain(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50629123(CHEMBL5436295)
Affinity DataIC50: 1nMAssay Description:Inhibition of human 8His-tagged AEP (V18 to Y433 residues) using Z-Ala-Ala-Asn-Rhl 10-(D-Pro) as substrate incubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetLegumain(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50629124(CHEMBL5424838)
Affinity DataIC50: 1nMAssay Description:Inhibition of human 8His-tagged AEP (V18 to Y433 residues) using Z-Ala-Ala-Asn-Rhl 10-(D-Pro) as substrate incubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetLegumain(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50629125(CHEMBL5396516)
Affinity DataIC50: 1nMAssay Description:Inhibition of human 8His-tagged AEP (V18 to Y433 residues) using Z-Ala-Ala-Asn-Rhl 10-(D-Pro) as substrate incubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetLegumain(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50510316(CHEMBL4549828)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC as substrate measured for every 2 mins for 60 mins by fluorescence-based microplate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLegumain(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50631600(CHEMBL5398959)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of recombinant AEP (unknown origin) using Z0AAn-Rh110 as peptide substrate measured for 15 to 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetLegumain(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50510339(CHEMBL4547118)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC as substrate measured for every 2 mins for 60 mins by fluorescence-based microplate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLegumain(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50631605(CHEMBL5415015)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of recombinant AEP (unknown origin) using Z0AAn-Rh110 as peptide substrate measured for 15 to 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetLegumain(Common tick)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50378246(CHEMBL584155)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of Ixodes ricinus asparaginyl endopeptidasesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLegumain(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50631592(CHEMBL5415184)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of recombinant AEP (unknown origin) using Z0AAn-Rh110 as peptide substrate measured for 15 to 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetLegumain(Common tick)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM22124(benzyl N-[(1S)-1-{[(2S)-1-[(2E)-3-[N-(carbamoylmet...)
Affinity DataIC50: 1.80nMT: 2°CAssay Description:AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLegumain(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50631582(CHEMBL5424036)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of recombinant AEP (unknown origin) using Z0AAn-Rh110 as peptide substrate measured for 15 to 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetLegumain(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50631597(CHEMBL5404830)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of recombinant AEP (unknown origin) using Z0AAn-Rh110 as peptide substrate measured for 15 to 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetLegumain(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50631615(CHEMBL5430648)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of recombinant AEP (unknown origin) using Z0AAn-Rh110 as peptide substrate measured for 15 to 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetLegumain(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50631611(CHEMBL5419035)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of recombinant AEP (unknown origin) using Z0AAn-Rh110 as peptide substrate measured for 15 to 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetLegumain(Common tick)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50378258(CHEMBL573249)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of Ixodes ricinus asparaginyl endopeptidasesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLegumain(Common tick)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50378268(CHEMBL573433)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of Ixodes ricinus asparaginyl endopeptidasesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLegumain(Common tick)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM22145(ethyl (2E)-4-[(2S)-2-[(2S)-2-{5-[(3aS,4S,6aR)-2-ox...)
Affinity DataIC50: 2.80nMT: 2°CAssay Description:AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetLegumain(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50631575(CHEMBL5406826)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of recombinant AEP (unknown origin) using Z0AAn-Rh110 as peptide substrate measured for 15 to 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
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