Compile Data Set for Download or QSAR
Report error Found 12 of ic50 data for polymerid = 238
TargetCD63 antigen(Human)
Gilead Sciences

US Patent
LigandPNGBDBM212272(US9504684, Ex.-3 | (R)-(4-(4-((6-(6-aminopyrazin-2...)
Affinity DataIC50: 33nMpH: 7.0Assay Description:Syk activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, Syk-ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCD63 antigen(Human)
Gilead Sciences

US Patent
LigandPNGBDBM212270(US9504684, Ex.-1 | 6-(6-amino-5-methylpyrazin-2-yl...)
Affinity DataIC50: 51nMpH: 7.0Assay Description:Syk activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, Syk-ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCD63 antigen(Human)
Gilead Sciences

US Patent
LigandPNGBDBM212271(US9504684, Ex.-2 | 6-(6-aminopyrazin-2-yl)-N-(4-(4...)
Affinity DataIC50: 80nMpH: 7.0Assay Description:Syk activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, Syk-ca...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCD63 antigen(Human)
Gilead Sciences

US Patent
LigandPNGBDBM324284((R)-1-(tert-butyl)-N-(8-(2-((1-methyl-1H-pyrazol-4...)
Affinity DataIC50: 82nMAssay Description:Inhibition of CD63 (unknown origin) assessed as FcepsilonR induced basophil activationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCD63 antigen(Human)
Gilead Sciences

US Patent
LigandPNGBDBM212277(US9504684, 6-(5-aminopyridin-3-yl)-N-(4-morpholino...)
Affinity DataIC50: 101nMpH: 7.0Assay Description:Syk activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, Syk-ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCD63 antigen(Human)
Gilead Sciences

US Patent
LigandPNGBDBM212274(US9504684, Ex.-5 | 2-(5-((6-(6-aminopyrazin-2-yl)i...)
Affinity DataIC50: 120nMpH: 7.0Assay Description:Syk activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, Syk-ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCD63 antigen(Human)
Gilead Sciences

US Patent
LigandPNGBDBM212275(US9504684, Ex.-6 | 2-((4-(4-((6-(6-aminopyrazin-2-...)
Affinity DataIC50: 128nMpH: 7.0Assay Description:Syk activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, Syk-ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCD63 antigen(Human)
Gilead Sciences

US Patent
LigandPNGBDBM212273(US9504684, Ex.-4 | 6-(6-aminopyrazin-2-yl)-5-methy...)
Affinity DataIC50: 157nMpH: 7.0Assay Description:Syk activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, Syk-ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCD63 antigen(Human)
Gilead Sciences

US Patent
LigandPNGBDBM212276(US9504684, Ex.-7 | 2-(5-((6-(6-amino-5-methylpyraz...)
Affinity DataIC50: 167nMpH: 7.0Assay Description:Syk activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, Syk-ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCD63 antigen(Human)
Gilead Sciences

US Patent
LigandPNGBDBM212279(US9504684, 6-(5-amino-6-methylpyridin-3-yl)-N-(4-m...)
Affinity DataIC50: 250nMpH: 7.0Assay Description:Syk activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, Syk-ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCD63 antigen(Human)
Gilead Sciences

US Patent
LigandPNGBDBM212280(US9504684, 6-(6-aminopyridin-3-yl)-N-(3,4-dimethox...)
Affinity DataIC50: 734nMpH: 7.0Assay Description:Syk activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, Syk-ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCD63 antigen(Human)
Gilead Sciences

US Patent
LigandPNGBDBM212278(US9504684, 6-(3-aminophenyl)-N-(3,4-dimethoxypheny...)
Affinity DataIC50: 809nMpH: 7.0Assay Description:Syk activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, Syk-ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent