Compile Data Set for Download or QSAR
Report error Found 240 of ic50 data for polymerid = 2260
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of California

Curated by ChEMBL
LigandPNGBDBM50114094(4-bromo-5-[(2R,3S)-4-(2-bromo-4,5-dihydroxyphenyl)...)
Affinity DataIC50: 57nMAssay Description:Inhibitory activity against soybean 1-lipoxygenase (SLO)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of California

Curated by ChEMBL
LigandPNGBDBM50114093(4-chloro-5-[(2R,3S)-4-(2-chloro-4,5-dihydroxypheny...)
Affinity DataIC50: 65nMAssay Description:Inhibitory activity against soybean 1-lipoxygenase (SLO)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of California

Curated by ChEMBL
LigandPNGBDBM22364(CHEMBL372548 | 1-(4-hydroxy-3-methoxyphenyl)-3-(4-...)
Affinity DataIC50: 100nMAssay Description:The COX enzyme activities were measured using the COX Inhibitor Screening Assay kit provided by Cayman (Cayman, Chemical Co., Ann Arbor, MI). The as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of California

Curated by ChEMBL
LigandPNGBDBM22364(CHEMBL372548 | 1-(4-hydroxy-3-methoxyphenyl)-3-(4-...)
Affinity DataIC50: 100nMAssay Description:In vitro inhibitory activity against 15-lipoxygenase obtained from soybeanMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of California

Curated by ChEMBL
LigandPNGBDBM50114097(4-[4-(2,2-dimethylbenzo[d][1,3]dioxol-5-yl)-2,3-di...)
Affinity DataIC50: 140nMAssay Description:Inhibitory activity against soybean 1-lipoxygenase (SLO)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of California

Curated by ChEMBL
LigandPNGBDBM50114096(4-ethyl-5-[4-(2-ethyl-4,5-dihydroxyphenyl)-2,3-dim...)
Affinity DataIC50: 140nMAssay Description:Inhibitory activity against soybean 1-lipoxygenase (SLO)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of California

Curated by ChEMBL
LigandPNGBDBM50065996(4-[4-(4-Hydroxy-3-methoxy-phenyl)-2,3-dimethyl-but...)
Affinity DataIC50: 170nMAssay Description:Inhibitory activity against soybean 1-lipoxygenase (SLO)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of California

Curated by ChEMBL
LigandPNGBDBM22372(Nordihydroguaiaretic Acid | CHEMBL313972 | 4-[(2S,...)
Affinity DataIC50: 180nMAssay Description:Inhibitory activity against soybean 1-lipoxygenase (SLO)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of California

Curated by ChEMBL
LigandPNGBDBM22363(3-(4-methanesulfonylphenyl)-1-(4-methoxynaphthalen...)
Affinity DataIC50: 300nMAssay Description:The COX enzyme activities were measured using the COX Inhibitor Screening Assay kit provided by Cayman (Cayman, Chemical Co., Ann Arbor, MI). The as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of California

Curated by ChEMBL
LigandPNGBDBM22365(1-(3-hydroxy-4-methoxyphenyl)-3-(4-methanesulfonyl...)
Affinity DataIC50: 300nMAssay Description:The COX enzyme activities were measured using the COX Inhibitor Screening Assay kit provided by Cayman (Cayman, Chemical Co., Ann Arbor, MI). The as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of California

Curated by ChEMBL
LigandPNGBDBM22354(CHEMBL194297 | 1-(4-hydroxyphenyl)-3-(4-methanesul...)
Affinity DataIC50: 300nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase obtained from potatoMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of California

Curated by ChEMBL
LigandPNGBDBM22356(CHEMBL364739 | 1-(3-hydroxyphenyl)-3-(4-methanesul...)
Affinity DataIC50: 300nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase obtained from potatoMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of California

Curated by ChEMBL
LigandPNGBDBM22365(1-(3-hydroxy-4-methoxyphenyl)-3-(4-methanesulfonyl...)
Affinity DataIC50: 300nMAssay Description:In vitro inhibitory activity against 15-lipoxygenase obtained from soybeanMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of California

Curated by ChEMBL
LigandPNGBDBM22354(CHEMBL194297 | 1-(4-hydroxyphenyl)-3-(4-methanesul...)
Affinity DataIC50: 320nMAssay Description:The COX enzyme activities were measured using the COX Inhibitor Screening Assay kit provided by Cayman (Cayman, Chemical Co., Ann Arbor, MI). The as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of California

Curated by ChEMBL
LigandPNGBDBM22354(CHEMBL194297 | 1-(4-hydroxyphenyl)-3-(4-methanesul...)
Affinity DataIC50: 320nMAssay Description:In vitro inhibitory activity against 15-lipoxygenase obtained from soybeanMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of California

Curated by ChEMBL
LigandPNGBDBM22348(3-(4-methanesulfonylphenyl)-1-[4-(propan-2-yl)phen...)
Affinity DataIC50: 360nMAssay Description:The COX enzyme activities were measured using the COX Inhibitor Screening Assay kit provided by Cayman (Cayman, Chemical Co., Ann Arbor, MI). The as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of California

Curated by ChEMBL
LigandPNGBDBM22370(3-(4-methanesulfonylphenyl)-1-[4-(methylsulfanyl)p...)
Affinity DataIC50: 360nMAssay Description:The COX enzyme activities were measured using the COX Inhibitor Screening Assay kit provided by Cayman (Cayman, Chemical Co., Ann Arbor, MI). The as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of California

Curated by ChEMBL
LigandPNGBDBM50135282(CHEMBL3746867)
Affinity DataIC50: 400nMAssay Description:Inhibition of soybean LOX1 assessed as reduction in linoleic acid oxidation measured every 10 s for 10 mins by spectrophotometry analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of California

Curated by ChEMBL
LigandPNGBDBM22352(CHEMBL197573 | 1-(3,4-difluorophenyl)-3-(4-methane...)
Affinity DataIC50: 400nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase obtained from potatoMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of California

Curated by ChEMBL
LigandPNGBDBM22356(CHEMBL364739 | 1-(3-hydroxyphenyl)-3-(4-methanesul...)
Affinity DataIC50: 500nMAssay Description:The COX enzyme activities were measured using the COX Inhibitor Screening Assay kit provided by Cayman (Cayman, Chemical Co., Ann Arbor, MI). The as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of California

Curated by ChEMBL
LigandPNGBDBM22356(CHEMBL364739 | 1-(3-hydroxyphenyl)-3-(4-methanesul...)
Affinity DataIC50: 500nMAssay Description:In vitro inhibitory activity against 15-lipoxygenase obtained from soybeanMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of California

Curated by ChEMBL
LigandPNGBDBM192765(1,3-Dimethoxy-5-methyl-2-((2E,6E)-3,7,11-trimethyl...)
Affinity DataIC50: 520nMpH: 7.0 T: 2°CAssay Description:Solution A was 50 mm DMAB in an 100 mm phosphate buffer (pH 7.0). Solution B was a mixture of 10 mm MBTH (3 mL) and hemoglobin (5 mg/mL, 3 mL) in 50 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of California

Curated by ChEMBL
LigandPNGBDBM22351(1-(4-fluorophenyl)-3-(4-methanesulfonylphenyl)prop...)
Affinity DataIC50: 1.00E+3nMAssay Description:The COX enzyme activities were measured using the COX Inhibitor Screening Assay kit provided by Cayman (Cayman, Chemical Co., Ann Arbor, MI). The as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of California

Curated by ChEMBL
LigandPNGBDBM50135284(CHEMBL3746105)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of soybean LOX1 assessed as reduction in linoleic acid oxidation measured every 10 s for 10 mins by spectrophotometry analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of California

Curated by ChEMBL
LigandPNGBDBM22231(CHEMBL267476 | (9Z,12Z)-octadeca-9,12-dienoic acid...)
Affinity DataIC50: 1.00E+3nMAssay Description:Allosteric inhibition of soybean LO1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of California

Curated by ChEMBL
LigandPNGBDBM22351(1-(4-fluorophenyl)-3-(4-methanesulfonylphenyl)prop...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibitory activity against 15-lipoxygenase obtained from soybeanMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of California

Curated by ChEMBL
LigandPNGBDBM22350(CHEMBL362923 | 4-[3-(4-methanesulfonylphenyl)prop-...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase obtained from potatoMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of California

Curated by ChEMBL
LigandPNGBDBM50093887(dodecyl gallate | Dodecyl 3,4,5-trihydroxybenzoate...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of soybean LOX-1More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of California

Curated by ChEMBL
LigandPNGBDBM234409([Au(tpp)Cl] (1))
Affinity DataIC50: 1.20E+3nMT: 2°CAssay Description:Enzyme activity was monitored by UV analysis. 0.05 cm^3 of enzyme solution was added to a cuvette containing 2 cm^3 linoleic acid solution and the ap...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of California

Curated by ChEMBL
LigandPNGBDBM32020(LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of soybean lipoxygenase after 7 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of California

Curated by ChEMBL
LigandPNGBDBM4375(3,4-Dihydroxycinnamate, XVII | cid_689043 | Caffei...)
Affinity DataIC50: 3.00E+3nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase obtained from potatoMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of California

Curated by ChEMBL
LigandPNGBDBM50065995(4-[(2S,3R)-4-(3,4-Dimethoxy-phenyl)-2,3-dimethyl-b...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibitory activity against soybean 1-lipoxygenase (SLO)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of California

Curated by ChEMBL
LigandPNGBDBM22346(3-(4-methanesulfonylphenyl)-1-(4-propylphenyl)prop...)
Affinity DataIC50: 3.20E+3nMAssay Description:The COX enzyme activities were measured using the COX Inhibitor Screening Assay kit provided by Cayman (Cayman, Chemical Co., Ann Arbor, MI). The as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of California

Curated by ChEMBL
LigandPNGBDBM22350(CHEMBL362923 | 4-[3-(4-methanesulfonylphenyl)prop-...)
Affinity DataIC50: 3.20E+3nMAssay Description:The COX enzyme activities were measured using the COX Inhibitor Screening Assay kit provided by Cayman (Cayman, Chemical Co., Ann Arbor, MI). The as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of California

Curated by ChEMBL
LigandPNGBDBM22352(CHEMBL197573 | 1-(3,4-difluorophenyl)-3-(4-methane...)
Affinity DataIC50: 3.20E+3nMAssay Description:The COX enzyme activities were measured using the COX Inhibitor Screening Assay kit provided by Cayman (Cayman, Chemical Co., Ann Arbor, MI). The as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of California

Curated by ChEMBL
LigandPNGBDBM7459(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...)
Affinity DataIC50: 3.20E+3nMAssay Description:The COX enzyme activities were measured using the COX Inhibitor Screening Assay kit provided by Cayman (Cayman, Chemical Co., Ann Arbor, MI). The as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of California

Curated by ChEMBL
LigandPNGBDBM22352(CHEMBL197573 | 1-(3,4-difluorophenyl)-3-(4-methane...)
Affinity DataIC50: 3.20E+3nMAssay Description:In vitro inhibitory activity against 15-lipoxygenase obtained from soybeanMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of California

Curated by ChEMBL
LigandPNGBDBM22350(CHEMBL362923 | 4-[3-(4-methanesulfonylphenyl)prop-...)
Affinity DataIC50: 3.20E+3nMAssay Description:In vitro inhibitory activity against 15-lipoxygenase obtained from soybeanMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of California

Curated by ChEMBL
LigandPNGBDBM7459(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...)
Affinity DataIC50: 3.20E+3nMAssay Description:In vitro inhibitory activity against 15-lipoxygenase obtained from soybeanMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of California

Curated by ChEMBL
LigandPNGBDBM22353(CHEMBL371191 | 3-(4-methanesulfonylphenyl)-1-(4-me...)
Affinity DataIC50: 3.50E+3nMAssay Description:The COX enzyme activities were measured using the COX Inhibitor Screening Assay kit provided by Cayman (Cayman, Chemical Co., Ann Arbor, MI). The as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of California

Curated by ChEMBL
LigandPNGBDBM22368(3-(4-methanesulfonylphenyl)-1-(3-nitrophenyl)prop-...)
Affinity DataIC50: 3.50E+3nMAssay Description:The COX enzyme activities were measured using the COX Inhibitor Screening Assay kit provided by Cayman (Cayman, Chemical Co., Ann Arbor, MI). The as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of California

Curated by ChEMBL
LigandPNGBDBM22372(Nordihydroguaiaretic Acid | CHEMBL313972 | 4-[(2S,...)
Affinity DataIC50: 3.50E+3nMAssay Description:The COX enzyme activities were measured using the COX Inhibitor Screening Assay kit provided by Cayman (Cayman, Chemical Co., Ann Arbor, MI). The as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of California

Curated by ChEMBL
LigandPNGBDBM22353(CHEMBL371191 | 3-(4-methanesulfonylphenyl)-1-(4-me...)
Affinity DataIC50: 3.50E+3nMAssay Description:In vitro inhibitory activity against 15-lipoxygenase obtained from soybeanMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of California

Curated by ChEMBL
LigandPNGBDBM22372(Nordihydroguaiaretic Acid | CHEMBL313972 | 4-[(2S,...)
Affinity DataIC50: 3.50E+3nMAssay Description:In vitro inhibitory activity against 15-lipoxygenase obtained from soybeanMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of California

Curated by ChEMBL
LigandPNGBDBM50135281(CHEMBL3747483)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of soybean LOX1 assessed as reduction in linoleic acid oxidation measured every 10 s for 10 mins by spectrophotometry analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of California

Curated by ChEMBL
LigandPNGBDBM22359(methyl 4-[3-(4-methanesulfonylphenyl)prop-2-ynoyl]...)
Affinity DataIC50: 5.00E+3nMAssay Description:The COX enzyme activities were measured using the COX Inhibitor Screening Assay kit provided by Cayman (Cayman, Chemical Co., Ann Arbor, MI). The as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of California

Curated by ChEMBL
LigandPNGBDBM192764((E)-2-(3,7-Dimethylocta-2,6-dien-1-yl)-1,3-dimetho...)
Affinity DataIC50: 5.30E+3nMpH: 7.0 T: 2°CAssay Description:Solution A was 50 mm DMAB in an 100 mm phosphate buffer (pH 7.0). Solution B was a mixture of 10 mm MBTH (3 mL) and hemoglobin (5 mg/mL, 3 mL) in 50 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of California

Curated by ChEMBL
LigandPNGBDBM50292424(Anacardic acid 10'Z-monoene | CHEMBL470264)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of soybean lipoxygenase-1More data for this Ligand-Target Pair
In DepthDetails Article

TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of California

Curated by ChEMBL
LigandPNGBDBM22358(3-(4-methanesulfonylphenyl)-1-(3,4,5-trimethoxyphe...)
Affinity DataIC50: 7.00E+3nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase obtained from potatoMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of California

Curated by ChEMBL
LigandPNGBDBM192763(1,3-Dimethoxy-5-methyl-2-(3-methylbut-2-en-1-yl)be...)
Affinity DataIC50: 7.60E+3nMpH: 7.0 T: 2°CAssay Description:Solution A was 50 mm DMAB in an 100 mm phosphate buffer (pH 7.0). Solution B was a mixture of 10 mm MBTH (3 mL) and hemoglobin (5 mg/mL, 3 mL) in 50 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
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