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TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580332(CHEMBL5081575)
Affinity DataIC50: 0.130nMAssay Description:Inhibition of recombinant human N-terminal met-His6-tagged matriptase catalytic domain (Gly596 to Val855 residues) expressed in Escherichia coli usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580343(CHEMBL5086585)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human N-terminal met-His6-tagged matriptase catalytic domain (Gly596 to Val855 residues) expressed in Escherichia coli usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580347(CHEMBL5091091)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant human N-terminal met-His6-tagged matriptase catalytic domain (Gly596 to Val855 residues) expressed in Escherichia coli usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580333(CHEMBL5081508)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of recombinant human N-terminal met-His6-tagged matriptase catalytic domain (Gly596 to Val855 residues) expressed in Escherichia coli usin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580338(CHEMBL5077855)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of recombinant human N-terminal met-His6-tagged matriptase catalytic domain (Gly596 to Val855 residues) expressed in Escherichia coli usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580334(CHEMBL5081335)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of recombinant human N-terminal met-His6-tagged matriptase catalytic domain (Gly596 to Val855 residues) expressed in Escherichia coli usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580339(CHEMBL5084226)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of recombinant human N-terminal met-His6-tagged matriptase catalytic domain (Gly596 to Val855 residues) expressed in Escherichia coli usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580344(CHEMBL5075134)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of recombinant human N-terminal met-His6-tagged matriptase catalytic domain (Gly596 to Val855 residues) expressed in Escherichia coli usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580342(CHEMBL5088958)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of recombinant human N-terminal met-His6-tagged matriptase catalytic domain (Gly596 to Val855 residues) expressed in Escherichia coli usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580340(CHEMBL5078472)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of recombinant human N-terminal met-His6-tagged matriptase catalytic domain (Gly596 to Val855 residues) expressed in Escherichia coli usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580331(CHEMBL5083517)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of recombinant human N-terminal met-His6-tagged matriptase catalytic domain (Gly596 to Val855 residues) expressed in Escherichia coli usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580345(CHEMBL5081851)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of recombinant human N-terminal met-His6-tagged matriptase catalytic domain (Gly596 to Val855 residues) expressed in Escherichia coli usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580337(CHEMBL5081090)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of recombinant human N-terminal met-His6-tagged matriptase catalytic domain (Gly596 to Val855 residues) expressed in Escherichia coli usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580341(CHEMBL5091578)
Affinity DataIC50: 7.70nMAssay Description:Inhibition of recombinant human N-terminal met-His6-tagged matriptase catalytic domain (Gly596 to Val855 residues) expressed in Escherichia coli usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580335(CHEMBL5092327)
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human N-terminal met-His6-tagged matriptase catalytic domain (Gly596 to Val855 residues) expressed in Escherichia coli usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50525905(CHEMBL4517343)
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human N-terminal Met and 6-His-tagged matriptase (G596 to V855 residues) expressed in Escherichia coli using Boc-QAR-AMC as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580330(CHEMBL5075263)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human N-terminal met-His6-tagged matriptase catalytic domain (Gly596 to Val855 residues) expressed in Escherichia coli usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580346(CHEMBL5074750)
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant human N-terminal met-His6-tagged matriptase catalytic domain (Gly596 to Val855 residues) expressed in Escherichia coli usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580336(CHEMBL5091873)
Affinity DataIC50: 41nMAssay Description:Inhibition of recombinant human N-terminal met-His6-tagged matriptase catalytic domain (Gly596 to Val855 residues) expressed in Escherichia coli usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM51911(3-(2-methoxyphenyl)-3-(4-methoxyphenyl)-N-[(4-prop...)
Affinity DataIC50: 420nMAssay Description:Inhibition of human matriptase measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM32709(1-(4-methylbenzoyl)-3-(3-pyridinyl)-1H-1,2,4-triaz...)
Affinity DataIC50: 570nMAssay Description:Inhibition of human matriptase measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50525900(CHEMBL4460168)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of recombinant human N-terminal Met and 6-His-tagged matriptase (G596 to V855 residues) expressed in Escherichia coli using Boc-QAR-AMC as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50525914(CHEMBL4558285)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of recombinant human N-terminal Met and 6-His-tagged matriptase (G596 to V855 residues) expressed in Escherichia coli using Boc-QAR-AMC as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50525899(CHEMBL4465265)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant human N-terminal Met and 6-His-tagged matriptase (G596 to V855 residues) expressed in Escherichia coli using Boc-QAR-AMC as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50525895(CHEMBL4447752)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant human N-terminal Met and 6-His-tagged matriptase (G596 to V855 residues) expressed in Escherichia coli using Boc-QAR-AMC as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50358189(CHEMBL1921967)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of acid-induced matriptase activation in human 184A1N4 cells using mAb M69 by cell-based ELISA like assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50525917(CHEMBL4579813)
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of recombinant human N-terminal Met and 6-His-tagged matriptase (G596 to V855 residues) expressed in Escherichia coli using Boc-QAR-AMC as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50358190(CHEMBL1921968)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of acid-induced matriptase activation in human 184A1N4 cells using mAb M69 by cell-based ELISA like assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50525903(CHEMBL4436048)
Affinity DataIC50: 7.94E+3nMAssay Description:Inhibition of recombinant human N-terminal Met and 6-His-tagged matriptase (G596 to V855 residues) expressed in Escherichia coli using Boc-QAR-AMC as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50525911(CHEMBL4535907)
Affinity DataIC50: 7.94E+3nMAssay Description:Inhibition of recombinant human N-terminal Met and 6-His-tagged matriptase (G596 to V855 residues) expressed in Escherichia coli using Boc-QAR-AMC as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50358188(CHEMBL1921966)
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of acid-induced matriptase activation in human 184A1N4 cells using mAb M69 by cell-based ELISA like assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50525912(CHEMBL4543039)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human N-terminal Met and 6-His-tagged matriptase (G596 to V855 residues) expressed in Escherichia coli using Boc-QAR-AMC as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50513785(CHEMBL4575658)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human matriptase using Boc-QAR-MCA as susbtrate measured every 60 secs for 10 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50513781(CHEMBL4466351)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human matriptase using Boc-QAR-MCA as susbtrate measured every 60 secs for 10 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50513783(CHEMBL4456620)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human matriptase using Boc-QAR-MCA as susbtrate measured every 60 secs for 10 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50525904(CHEMBL4461533)
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of recombinant human N-terminal Met and 6-His-tagged matriptase (G596 to V855 residues) expressed in Escherichia coli using Boc-QAR-AMC as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50358191(CHEMBL1921969)
Affinity DataIC50: 2.18E+4nMAssay Description:Inhibition of acid-induced matriptase activation in human 184A1N4 cells using mAb M69 by cell-based ELISA like assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50525897(CHEMBL4536142)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of recombinant human N-terminal Met and 6-His-tagged matriptase (G596 to V855 residues) expressed in Escherichia coli using Boc-QAR-AMC as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50525902(CHEMBL4547455)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of recombinant human N-terminal Met and 6-His-tagged matriptase (G596 to V855 residues) expressed in Escherichia coli using Boc-QAR-AMC as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50522493(CHEMBL4530083)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of recombinant human N-terminal met-His6-tagged matriptase catalytic domain (Gly596 to Val855 residues) expressed in Escherichia coli usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM33437(MLS000099650 | SMR000074479 | 1-(3,4-dimethoxybenz...)
Affinity DataIC50: 3.00E+4nMpH: 8.0Assay Description:Inhibition of human matriptase measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM33453((3-Amino-[1,2,4]triazol-4-yl)-(4-methoxy-phenyl)-m...)
Affinity DataIC50: 3.00E+4nMpH: 8.0Assay Description:Inhibition of human matriptase measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM33882(SMR000306508 | (5-azanyl-3-pyridin-3-yl-1,2,4-tria...)
Affinity DataIC50: 3.00E+4nMpH: 8.0Assay Description:Inhibition of human matriptase measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50525918(CHEMBL4473069)
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of recombinant human N-terminal Met and 6-His-tagged matriptase (G596 to V855 residues) expressed in Escherichia coli using Boc-QAR-AMC as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50525901(CHEMBL4448315)
Affinity DataIC50: 3.98E+4nMAssay Description:Inhibition of recombinant human N-terminal Met and 6-His-tagged matriptase (G596 to V855 residues) expressed in Escherichia coli using Boc-QAR-AMC as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50449676(CHEMBL4162159)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant human matriptase using Boc-QAR-MCA as substrate measured every 30 secs for 10 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50525913(CHEMBL4464120)
Affinity DataIC50: 6.31E+4nMAssay Description:Inhibition of recombinant human N-terminal Met and 6-His-tagged matriptase (G596 to V855 residues) expressed in Escherichia coli using Boc-QAR-AMC as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50444599(CHEMBL3099875)
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibition of matriptase (unknown origin) using Boc-Gln-Ala-Arg-AMC as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50444603(CHEMBL3099871)
Affinity DataIC50: 9.80E+4nMAssay Description:Inhibition of matriptase (unknown origin) using Boc-Gln-Ala-Arg-AMC as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50444597(CHEMBL3099882)
Affinity DataIC50: 1.03E+5nMAssay Description:Inhibition of matriptase (unknown origin) using Boc-Gln-Ala-Arg-AMC as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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