Compile Data Set for Download or QSAR
Report error Found 1325 of ic50 data for polymerid = 1932,1933,1934,1935,1936,50000048,50000343,50002311,50004802,50004810,50006591
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50226275(CHEMBL267104)
Affinity DataIC50: 0nMAssay Description:Compound was evaluated for inhibitory effect on the thymidylate synthase (TS) of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Mouse)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50049159((R)-2-((S)-4-Carboxy-4-{4-[(2,7-dimethyl-4-oxo-3,4...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of Thymidylate synthase activity in L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Mouse)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50288983((S)-2-((S)-4-Carboxy-4-{4-[(2,7-dimethyl-4-oxo-3,4...)
Affinity DataIC50: 0.400nMAssay Description:Compound was evaluated for the inhibition of Thymidylate synthase.More data for this Ligand-Target Pair
In DepthDetails Article

TargetThymidylate synthase(Mouse)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50340678(1-(beta-D-2-deoxy-erythro-pentofuranosyl)-5-fluoro...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 4 h...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Mouse)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50340678(1-(beta-D-2-deoxy-erythro-pentofuranosyl)-5-fluoro...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 24 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Mouse)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50288983((S)-2-((S)-4-Carboxy-4-{4-[(2,7-dimethyl-4-oxo-3,4...)
Affinity DataIC50: 0.400nMAssay Description:Compound was evaluated for the inhibition of Thymidylate synthase in experiment 1More data for this Ligand-Target Pair
In DepthDetails Article

TargetThymidylate synthase(Mouse)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50081273((S)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...)
Affinity DataIC50: 0.520nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Mouse)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50049168((R)-2-((S)-4-Carboxy-4-{4-[(2,7-dimethyl-4-oxo-3,4...)
Affinity DataIC50: 0.560nMAssay Description:Inhibition of Thymidylate synthase activity in L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Mouse)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50081256((S)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Mouse)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50340678(1-(beta-D-2-deoxy-erythro-pentofuranosyl)-5-fluoro...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 15 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Mouse)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50340678(1-(beta-D-2-deoxy-erythro-pentofuranosyl)-5-fluoro...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 15...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Mouse)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50081259((S)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...)
Affinity DataIC50: 0.620nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Mouse)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50340678(1-(beta-D-2-deoxy-erythro-pentofuranosyl)-5-fluoro...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 4 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Mouse)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50340678(1-(beta-D-2-deoxy-erythro-pentofuranosyl)-5-fluoro...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 24...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Mouse)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50288984((S)-4-[(S)-1-Carboxy-3-(1H-tetrazol-5-yl)-propylca...)
Affinity DataIC50: 0.820nMAssay Description:Compound was evaluated for the inhibition of Thymidylate synthase.More data for this Ligand-Target Pair
In DepthDetails Article

TargetThymidylate synthase(Mouse)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50288984((S)-4-[(S)-1-Carboxy-3-(1H-tetrazol-5-yl)-propylca...)
Affinity DataIC50: 0.820nMAssay Description:Compound was evaluated for the inhibition of Thymidylate synthase in experiment 1More data for this Ligand-Target Pair
In DepthDetails Article

TargetThymidylate synthase(Mouse)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50081265((S)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...)
Affinity DataIC50: 0.860nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Mouse)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50288985((S)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...)
Affinity DataIC50: 1nMAssay Description:Compound was evaluated for the inhibition of Thymidylate synthase.More data for this Ligand-Target Pair
In DepthDetails Article

TargetThymidylate synthase(Human)
Institute of Theoretical Studies Ggmbh

Curated by ChEMBL
LigandPNGBDBM50326712(2(R)-[4(S)-carboxy-4-[4-[N-(2-hydroxymethyl-4-oxo-...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of thymine synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Mouse)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50081240(2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazolin-6...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Mouse)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50081246((S)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Mouse)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50081252((S)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Mouse)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50081243(2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazolin-6...)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Mouse)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50081260((S)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...)
Affinity DataIC50: 1.62nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Mouse)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50081261((S)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Mouse)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50049170(CHEMBL301895 | CHEMBL353066 | (R)-2-((S)-4-Carboxy...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of Thymidylate synthase activity in L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Mouse)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50049172((R)-2-((S)-4-Carboxy-4-{2-fluoro-4-[(2-methyl-4-ox...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of Thymidylate synthase activity in L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Mouse)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50081247((S)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Mouse)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50107343((4-Chloro-butyl)-methyl-phosphoramidic acid 5-(5-f...)
Affinity DataIC50: 1.90nMAssay Description:Thymidylate synthase inhibition in thymidine kinase deficient /TK cells after 2 hr treatmentMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Mouse)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50049164(2-(4-Carboxy-4-{4-[(2-methyl-4-oxo-3,4-dihydro-qui...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Thymidylate synthase activity in L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Mouse)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50049175((S)-2-((S)-4-Carboxy-4-{4-[(2-methyl-4-oxo-3,4-dih...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Thymidylate synthase activity in L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Mouse)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50049176((R)-2-((S)-4-Carboxy-4-{4-[(2,7-dimethyl-4-oxo-3,4...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Thymidylate synthase activity in L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Mouse)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50081239((S)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...)
Affinity DataIC50: 2nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Mouse)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50081253((S)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...)
Affinity DataIC50: 2nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Mouse)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50037316((R)-2-((R)-4-Carboxy-4-{4-[(2-methyl-4-oxo-3,4-dih...)
Affinity DataIC50: 2nMAssay Description:Tested for inhibition against thymidylate synthase(TS) which is partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Mouse)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50037303(CHEMBL320794 | CHEMBL168553 | (R)-2-((R)-4-Carboxy...)
Affinity DataIC50: 2nMAssay Description:Tested for inhibition against thymidylate synthase(TS) which is partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Mouse)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50081272((S)-5-Acetylsulfamoyl-2-{4-[(2,7-dimethyl-4-oxo-3,...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Mouse)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50081264((S)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Mouse)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50081249(2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazolin-6...)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM18050(MTX | cid_126941 | Methotrexate | 2-[(4-{[(2,4-dia...)
Affinity DataIC50: 2.64nMAssay Description:Compound was evaluated for inhibitory effect on the thymidylate synthase (TS) of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50226277(CHEMBL273509)
Affinity DataIC50: 2.78nMAssay Description:Compound was evaluated for inhibitory effect on the thymidylate synthase (TS) of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Human)
Institute of Theoretical Studies Ggmbh

Curated by ChEMBL
LigandPNGBDBM50615583(CHEMBL321678)
Affinity DataIC50: 3nMAssay Description:Inhibition of human TSMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetThymidylate synthase(Human)
Institute of Theoretical Studies Ggmbh

Curated by ChEMBL
LigandPNGBDBM50615584(CHEMBL5267424)
Affinity DataIC50: 3nMAssay Description:Inhibition of human TSMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetThymidylate synthase(Human)
Institute of Theoretical Studies Ggmbh

Curated by ChEMBL
LigandPNGBDBM50615585(CHEMBL111859)
Affinity DataIC50: 3nMAssay Description:Inhibition of human TSMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetThymidylate synthase(Human)
Institute of Theoretical Studies Ggmbh

Curated by ChEMBL
LigandPNGBDBM50615586(CHEMBL113019)
Affinity DataIC50: 3nMAssay Description:Inhibition of human TSMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetThymidylate synthase(Human)
Institute of Theoretical Studies Ggmbh

Curated by ChEMBL
LigandPNGBDBM50615587(CHEMBL109881)
Affinity DataIC50: 3nMAssay Description:Inhibition of human TSMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetThymidylate synthase(Human)
Institute of Theoretical Studies Ggmbh

Curated by ChEMBL
LigandPNGBDBM50615588(CHEMBL320036)
Affinity DataIC50: 3nMAssay Description:Inhibition of human TSMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetThymidylate synthase(Human)
Institute of Theoretical Studies Ggmbh

Curated by ChEMBL
LigandPNGBDBM50615589(CHEMBL264198)
Affinity DataIC50: 3nMAssay Description:Inhibition of human TSMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetThymidylate synthase(Human)
Institute of Theoretical Studies Ggmbh

Curated by ChEMBL
LigandPNGBDBM50615590(CHEMBL5289121)
Affinity DataIC50: 3nMAssay Description:Inhibition of human TSMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetThymidylate synthase(Human)
Institute of Theoretical Studies Ggmbh

Curated by ChEMBL
LigandPNGBDBM50615591(CHEMBL5289689)
Affinity DataIC50: 3nMAssay Description:Inhibition of human TSMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
Displayed 1 to 50 (of 1325 total ) | Next | Last >>
Jump to: