Compile Data Set for Download or QSAR
Report error Found 6 of ic50 data for polymerid = 1631
TargetMitogen-activated protein kinase 14 [G110D](Mouse)
Merck Research Laboratories

LigandPNGBDBM15240(4-[1-methyl-2-(piperidin-4-yl)-4-[3-(trifluorometh...)
Affinity DataIC50: 0.140nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with wild-type or mutant p38alpha enzymes, and substrates in the presence ATP/[gam...More data for this Ligand-Target Pair
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PubMed
TargetMitogen-activated protein kinase 14 [G110D](Mouse)
Merck Research Laboratories

LigandPNGBDBM15242(1-(2,6-dichlorophenyl)-5-(2,4-difluorophenyl)-7-(p...)
Affinity DataIC50: 14nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with wild-type or mutant p38alpha enzymes, and substrates in the presence ATP/[gam...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14 [G110D](Mouse)
Merck Research Laboratories

LigandPNGBDBM13336(4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...)
Affinity DataIC50: 56nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with wild-type or mutant p38alpha enzymes, and substrates in the presence ATP/[gam...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14 [G110D](Mouse)
Merck Research Laboratories

LigandPNGBDBM15241(1-(2,6-dichlorophenyl)-5-(2,4-difluorophenyl)-7-(p...)
Affinity DataIC50: 67nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with wild-type or mutant p38alpha enzymes, and substrates in the presence ATP/[gam...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14 [G110D](Mouse)
Merck Research Laboratories

LigandPNGBDBM15244(cid_3038525 | 5-(2,6-dichlorophenyl)-2-[(2,4-diflu...)
Affinity DataIC50: 120nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with wild-type or mutant p38alpha enzymes, and substrates in the presence ATP/[gam...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 14 [G110D](Mouse)
Merck Research Laboratories

LigandPNGBDBM15243(1-(2,6-dichlorophenyl)-6-[(2,4-difluorophenyl)sulf...)
Affinity DataIC50: 160nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with wild-type or mutant p38alpha enzymes, and substrates in the presence ATP/[gam...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)