Compile Data Set for Download or QSAR
Report error Found 603 of ic50 data for polymerid = 1571
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

US Patent
LigandPNGBDBM677013(US11993596, Compound WX024 | US20240294526, Compou...)
Affinity DataIC50: 0.0400nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

US Patent
LigandPNGBDBM677009(US11993596, Compound WX018 | US20240294526, Compou...)
Affinity DataIC50: 0.0500nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

US Patent
LigandPNGBDBM677020(US11993596, Compound WX049 | US20240294526, Compou...)
Affinity DataIC50: 0.0500nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

US Patent
LigandPNGBDBM677003(US11993596, Compound WX004 | US20240294526, Compou...)
Affinity DataIC50: 0.120nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

US Patent
LigandPNGBDBM677018(US11993596, Compound WX047 | US20240294526, Compou...)
Affinity DataIC50: 0.160nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

US Patent
LigandPNGBDBM677022(US11993596, Compound WX052 | US20240294526, Compou...)
Affinity DataIC50: 0.180nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

US Patent
LigandPNGBDBM677007(US11993596, Compound WX016 | US20240294526, Compou...)
Affinity DataIC50: 0.240nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

US Patent
LigandPNGBDBM677021(US11993596, Compound WX050 | US20240294526, Compou...)
Affinity DataIC50: 0.240nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

US Patent
LigandPNGBDBM50532267(CHEMBL131355)
Affinity DataIC50: 0.270nMAssay Description:Inhibition of human His-tagged PDE3B catalytic domain expressed in Escherichia coli BL21(DE3) pLysS cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

US Patent
LigandPNGBDBM50532267(CHEMBL131355)
Affinity DataIC50: 0.270nMAssay Description:Inhibition of human His-tagged PDE3B catalytic domain expressed in Escherichia coli BL21(DE3) pLysS cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

US Patent
LigandPNGBDBM677019(US11993596, Compound WX048 | US20240294526, Compou...)
Affinity DataIC50: 0.270nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

US Patent
LigandPNGBDBM677016(US11993596, Compound WX036 | US20240294526, Compou...)
Affinity DataIC50: 0.410nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

US Patent
LigandPNGBDBM677008(US11993596, Compound WX017 | US20240294526, Compou...)
Affinity DataIC50: 0.430nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

US Patent
LigandPNGBDBM677014(US11993596, Compound WX025 | US20240294526, Compou...)
Affinity DataIC50: 0.440nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

US Patent
LigandPNGBDBM677011(US11993596, Compound WX020 | US20240294526, Compou...)
Affinity DataIC50: 0.470nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

US Patent
LigandPNGBDBM677010(US11993596, Compound WX019 | US20240294526, Compou...)
Affinity DataIC50: 0.480nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

US Patent
LigandPNGBDBM677006(US11993596, Compound WX015 | US20240294526, Compou...)
Affinity DataIC50: 0.560nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

US Patent
LigandPNGBDBM677012(US11993596, Compound WX021 | US20240294526, Compou...)
Affinity DataIC50: 1.10nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

US Patent
LigandPNGBDBM677028(US11993596, Compound WX064 | US20240294526, Compou...)
Affinity DataIC50: 1.40nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

US Patent
LigandPNGBDBM677017(US11993596, Compound WX037 | US20240294526, Compou...)
Affinity DataIC50: 1.70nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

US Patent
LigandPNGBDBM677023(US11993596, Compound WX053 | US20240294526, Compou...)
Affinity DataIC50: 1.90nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

US Patent
LigandPNGBDBM677025(US11993596, Compound WX055 | US20240294526, Compou...)
Affinity DataIC50: 2.10nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

US Patent
LigandPNGBDBM677002(US11993596, Compound WX003 | US20240294526, Compou...)
Affinity DataIC50: 2.20nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

US Patent
LigandPNGBDBM677015(US11993596, Compound WX026 | US20240294526, Compou...)
Affinity DataIC50: 2.5nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

US Patent
LigandPNGBDBM677024(US11993596, Compound WX054 | US20240294526, Compou...)
Affinity DataIC50: 2.70nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

US Patent
LigandPNGBDBM568667((6S)-6-Methyl-5-[4-(morpholin-4-yl)-3-(trifluorome...)
Affinity DataIC50: 4nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

US Patent
LigandPNGBDBM50572924(CHEMBL4876937)
Affinity DataIC50: 5nMAssay Description:Inhibition of human full length PDE3B expressed in Sf9 cells measured after 60 mins by [3H]-cAMP Scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

US Patent
LigandPNGBDBM50572925(CHEMBL4877229)
Affinity DataIC50: 5nMAssay Description:Inhibition of human full length PDE3B expressed in Sf9 cells measured after 60 mins by [3H]-cAMP Scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

US Patent
LigandPNGBDBM677001(US11993596, Compound WX002 | US20240294526, Compou...)
Affinity DataIC50: 5nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

US Patent
LigandPNGBDBM677027(US11993596, Compound WX057 | US20240294526, Compou...)
Affinity DataIC50: 5.40nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

US Patent
LigandPNGBDBM677004(US11993596, Compound WX005 | US20240294526, Compou...)
Affinity DataIC50: 5.70nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

US Patent
LigandPNGBDBM677000(US11993596, Compound WX001 | US20240294526, Compou...)
Affinity DataIC50: 6.5nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

US Patent
LigandPNGBDBM50572927(CHEMBL4862024)
Affinity DataIC50: 7nMAssay Description:Inhibition of human full length PDE3B expressed in Sf9 cells measured after 60 mins by [3H]-cAMP Scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

US Patent
LigandPNGBDBM568827(US11427553, Example Intermediate 67)
Affinity DataIC50: 7nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

US Patent
LigandPNGBDBM568669((rac)-6-Methyl-5-(4-morpholino-3-(trifluoromethyl)...)
Affinity DataIC50: 8nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

US Patent
LigandPNGBDBM50572926(CHEMBL4853029)
Affinity DataIC50: 9nMAssay Description:Inhibition of human full length PDE3B expressed in Sf9 cells measured after 60 mins by [3H]-cAMP Scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

US Patent
LigandPNGBDBM568764(5-[4-(4-Hydroxypiperidin-1-yl)-3-(trifluoromethyl)...)
Affinity DataIC50: 9nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

US Patent
LigandPNGBDBM568817((6S)-5-[4-(3-Hydroxy-3-methylazetidin-1-yl)-3-(tri...)
Affinity DataIC50: 9nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

US Patent
LigandPNGBDBM677026(US11993596, Compound WX056 | US20240294526, Compou...)
Affinity DataIC50: 9.10nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

US Patent
LigandPNGBDBM677005(US11993596, Compound WX010 | US20240294526, Compou...)
Affinity DataIC50: 9.80nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

US Patent
LigandPNGBDBM568809((trans)-5-{4-[4-hydroxycyclohexyl]-3-(trifluoromet...)
Affinity DataIC50: 10nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

US Patent
LigandPNGBDBM50615690(CHEMBL5286823)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant PDE3BMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

US Patent
LigandPNGBDBM568666((rac)-5-(3-Fluoro-4-morpholinophenyl)-6-methyl-3,6...)
Affinity DataIC50: 13nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

US Patent
LigandPNGBDBM50615689(CHEMBL5283715)
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant PDE3BMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

US Patent
LigandPNGBDBM568581((6S)-5-(3,5-Difluoro-4-morpholinophenyl)-6-methyl-...)
Affinity DataIC50: 15nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

US Patent
LigandPNGBDBM568713(US11427553, Example 188 | (6S)-5-[4′-Hydroxy...)
Affinity DataIC50: 16nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

US Patent
LigandPNGBDBM568851(5-[4-(3-methyl-1H-indazol-6-yl)-3-(trifluoromethyl...)
Affinity DataIC50: 16nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

US Patent
LigandPNGBDBM15298(N-{4-[(4R)-4-methyl-6-oxo-1,4,5,6-tetrahydropyrida...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant PDE3BMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

US Patent
LigandPNGBDBM568574((rac)-5-[3,5-Difluoro-4-(morpholin-4-yl)phenyl]-6-...)
Affinity DataIC50: 17nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

US Patent
LigandPNGBDBM568833(5-[4-(3-Methyl-1H-pyrazol-4-yl)-3-(trifluoromethyl...)
Affinity DataIC50: 17nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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US Patent

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