Compile Data Set for Download or QSAR
Report error Found 1005 of ic50 data for polymerid = 1250,50002227
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50389100(CHEMBL2064547)
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of MMP8 using (7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl)Ala-Arg-NH2 as substrate incuba...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50389101(CHEMBL2064548)
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of MMP8 using (7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl)Ala-Arg-NH2 as substrate incuba...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50389096(CHEMBL2064549)
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of MMP8 using (7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl)Ala-Arg-NH2 as substrate incuba...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50031795((N-(2-HYDROXAMATEMETHYLENE-4-METHYL-PENTOYL)PHENYL...)
Affinity DataIC50: 0.0460nMAssay Description:Inhibition of human recombinant MMP8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50493268(CHEMBL2425938)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of MMP-8 (unknown origin) using 7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diamino-propionyl)Ala-Arg-NH2 a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM11863(CHEMBL440498 | alpha-tetrahydropyran beta-sulfone ...)
Affinity DataIC50: 0.0970nMAssay Description:Inhibition of human recombinant MMP8 using fluorescence peptide Cy3-PLGLK(Cy5Q)AR-NH2 substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM11863(CHEMBL440498 | alpha-tetrahydropyran beta-sulfone ...)
Affinity DataIC50: 0.0970nMAssay Description:Inhibition of human recombinant MMP8 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate after 40 mins by spectrofluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM11863(CHEMBL440498 | alpha-tetrahydropyran beta-sulfone ...)
Affinity DataIC50: 0.0970nMAssay Description:Inhibition of recombinant human AMPA-activated MMP8 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM11863(CHEMBL440498 | alpha-tetrahydropyran beta-sulfone ...)
Affinity DataIC50: 0.0970nMAssay Description:Inhibition of APMA-activated recombinant human MMP-8 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric m...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50389106(CHEMBL2064542)
Affinity DataIC50: 0.110nMAssay Description:Inhibition of MMP8 using (7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl)Ala-Arg-NH2 as substrate incuba...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50082965((2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-p...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of MMP-8 (matrix metalloprotease-8)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50389107(CHEMBL2064541)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of MMP8 using (7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl)Ala-Arg-NH2 as substrate incuba...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50493277(CHEMBL2425950)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of MMP-8 (unknown origin) using 7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diamino-propionyl)Ala-Arg-NH2 a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50493279(CHEMBL2425943)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of MMP-8 (unknown origin) using 7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diamino-propionyl)Ala-Arg-NH2 a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50246599(N-(4-Phenoxybenzenesulfonyl)-N-{[2-(4-sulfamoylphe...)
Affinity DataIC50: 0.290nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50493274(CHEMBL2425944)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of MMP-8 (unknown origin) using 7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diamino-propionyl)Ala-Arg-NH2 a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50493275(CHEMBL2425941)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of MMP-8 (unknown origin) using 7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diamino-propionyl)Ala-Arg-NH2 a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50198038([(R)-1-(4'-ethoxy-biphenyl-4-sulfonylamino)-2-meth...)
Affinity DataIC50: 0.370nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50198033([(R)-2-methyl-1-(4'-methyl-biphenyl-4-sulfonylamin...)
Affinity DataIC50: 0.390nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50198033([(R)-2-methyl-1-(4'-methyl-biphenyl-4-sulfonylamin...)
Affinity DataIC50: 0.390nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50198035([(R)-2-methyl-1-(3'-methyl-biphenyl-4-sulfonylamin...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50273426(N-(4-Phenoxybenzenesulfonyl)-N-hydroxycarbonylmeth...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50348677(CHEMBL1801399)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human MMP8 assessed as cleavage of fluorogenic peptide MCAPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50348669(CHEMBL1801054)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human MMP8 assessed as cleavage of fluorogenic peptide MCAPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50348676(CHEMBL1801044)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human MMP8 assessed as cleavage of fluorogenic peptide MCAPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50148208(3-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-8-ox...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of matrix metalloprotease-8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50493278(CHEMBL2425947)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of MMP-8 (unknown origin) using 7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diamino-propionyl)Ala-Arg-NH2 a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50493269(CHEMBL2425936)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of MMP-8 (unknown origin) using 7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diamino-propionyl)Ala-Arg-NH2 a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50063917(CHEMBL279785 | marimastat | cid_119031 | (2S,3R)-N...)
Affinity DataIC50: 0.470nMAssay Description:Inhibition of Matrix metalloprotease-8 (MMP-8) in fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50063917(CHEMBL279785 | marimastat | cid_119031 | (2S,3R)-N...)
Affinity DataIC50: 0.470nMAssay Description:Inhibition of MMP-8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50102477(4-[Carboxy-(4'-methoxy-biphenyl-4-sulfonylamino)-m...)
Affinity DataIC50: 0.5nMAssay Description:Inhibitory activity against matrix metalloprotease-8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50389104(CHEMBL2064552)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of MMP8 using (7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl)Ala-Arg-NH2 as substrate incuba...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50493272(CHEMBL2425949)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of MMP-8 (unknown origin) using 7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diamino-propionyl)Ala-Arg-NH2 a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50082556(AG-3340 | 2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benz...)
Affinity DataIC50: 0.540nMAssay Description:Inhibition of Matrix metalloprotease-8 (MMP-8) in fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50129986(2-(((S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-...)
Affinity DataIC50: 0.560nMAssay Description:Inhibition of matrix metalloprotease-8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50610465(CHEMBL5288452)
Affinity DataIC50: 0.567nMAssay Description:Inhibition of MMP8 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50348650(CHEMBL1801431)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human MMP8 assessed as cleavage of fluorogenic peptide MCAPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50082548((S)-4-(4-Methoxy-benzenesulfonyl)-2,2-dimethyl-[1,...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of neutrophil collagenase (Matrix metalloprotease-8)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50348652(CHEMBL1801429)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human MMP8 assessed as cleavage of fluorogenic peptide MCAPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50082537((S)-4-(4-Methoxy-benzenesulfonyl)-2,2-dimethyl-thi...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of neutrophil collagenase (Matrix metalloprotease-8)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50254802(CHEMBL4088630)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of MMP8 (unknown origin) expressed in Escherichia coli BL21(DE3) using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate after 20 to 30 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50493267(CHEMBL2425939)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of MMP-8 (unknown origin) using 7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diamino-propionyl)Ala-Arg-NH2 a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50241252(2-[hydroxycarbamoylmethyl-(4-phenoxy-benzenesulfon...)
Affinity DataIC50: 0.740nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50090259((4-Benzyl-benzyl)-[2-((S)-2,2-dimethyl-1-methylcar...)
Affinity DataIC50: 0.770nMAssay Description:Inhibition of matrix metalloprotease-8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50198034([(R)-1-(4'-chloro-biphenyl-4-sulfonylamino)-2-meth...)
Affinity DataIC50: 0.810nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50203953(CHEMBL3932562)
Affinity DataIC50: 0.820nMAssay Description:Inhibition of recombinant human AMPA-activated MMP8 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50348670(CHEMBL1801052)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human MMP8 assessed as cleavage of fluorogenic peptide MCAPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50225411((R)-2-(N-((6-fluoropyridin-3-yl)methyl)-4-methoxyp...)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50493281(CHEMBL2425932)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of MMP-8 (unknown origin) using 7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diamino-propionyl)Ala-Arg-NH2 a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50082446(7-Hydroxy-2-(4-methoxy-benzenesulfonyl)-1,2,3,4-te...)
Affinity DataIC50: 1nMAssay Description:Inhibitory concentration against human matrix metalloprotease-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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