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Found
366
of ic50 data for polymerid = 1206,1209
Target
Three-prime repair exonuclease 1
(Human)
Constellation Pharmaceuticals
US Patent
Ligand
BDBM707968
(2-(3-bromo-5-methylphenyl)-5-hydroxy-N-(isoxazol-4...)
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Affinity Data
IC50: 10nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Three-prime repair exonuclease 1
(Human)
Constellation Pharmaceuticals
US Patent
Ligand
BDBM707972
(2-(3-bromo-2- methylphenyl)-5- hydroxy-N-(isoxazol...)
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Affinity Data
IC50: 10nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Three-prime repair exonuclease 1
(Human)
Constellation Pharmaceuticals
US Patent
Ligand
BDBM707977
(2-(3-bromophenyl)-5- hydroxy-N-(isoxazol-4- yl)-1-...)
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Affinity Data
IC50: 10nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Three-prime repair exonuclease 1
(Human)
Constellation Pharmaceuticals
US Patent
Ligand
BDBM707982
(2-(3-bromo-2-(2-hydroxyethoxy)phenyl)-5-hydroxy-N-...)
Copy SMILES
Affinity Data
IC50: 10nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Three-prime repair exonuclease 1
(Human)
Constellation Pharmaceuticals
US Patent
Ligand
BDBM708010
(5-hydroxy-N- (isoxazol-4-yl)-1- methyl-6-oxo-2-(1-...)
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Affinity Data
IC50: 10nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Three-prime repair exonuclease 1
(Human)
Constellation Pharmaceuticals
US Patent
Ligand
BDBM708012
(2-(1-(3- chlorobenzoyl) piperidin-3-yl)- 5-hydroxy...)
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Affinity Data
IC50: 10nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Three-prime repair exonuclease 1
(Human)
Constellation Pharmaceuticals
US Patent
Ligand
BDBM708022
(5-hydroxy-N- (isoxazol-4-yl)-1- methyl-2-(3-methyl...)
Copy SMILES
Affinity Data
IC50: 10nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Three-prime repair exonuclease 1
(Human)
Constellation Pharmaceuticals
US Patent
Ligand
BDBM708035
(2-(5-bromo-2-(2- hydroxyethoxy) phenyl)-5-hydroxy-...)
Copy SMILES
Affinity Data
IC50: 10nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Three-prime repair exonuclease 1
(Human)
Constellation Pharmaceuticals
US Patent
Ligand
BDBM708040
(2-(3-bromo-2-(2- hydroxyethyl)phenyl)- 5-hydroxy-N...)
Copy SMILES
Affinity Data
IC50: 10nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Three-prime repair exonuclease 1
(Human)
Constellation Pharmaceuticals
US Patent
Ligand
BDBM708041
((R)-5-hydroxy-N- (isoxazol-4-yl)-1- methyl-6-oxo-2...)
Copy SMILES
Affinity Data
IC50: 10nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Three-prime repair exonuclease 1
(Human)
Constellation Pharmaceuticals
US Patent
Ligand
BDBM708042
((S)-5-hydroxy-N- (isoxazol-4-yl)-1- methyl-6-oxo-2...)
Copy SMILES
Affinity Data
IC50: 10nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Three-prime repair exonuclease 1
(Human)
Constellation Pharmaceuticals
US Patent
Ligand
BDBM708045
(2-((3S,6S)-1-(3,4- dichlorobenzoyl)-6- methylpiper...)
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Affinity Data
IC50: 10nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Three-prime repair exonuclease 1
(Human)
Constellation Pharmaceuticals
US Patent
Ligand
BDBM708049
((S)-2-(1-(3-chloro-4- fluorobenzoyl)piperidin-3-yl...)
Copy SMILES
Affinity Data
IC50: 10nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Three-prime repair exonuclease 1
(Human)
Constellation Pharmaceuticals
US Patent
Ligand
BDBM708056
((S)-2-(1-(3,4- dichlorobenzoyl)piperidin-3-yl)-5- ...)
Copy SMILES
Affinity Data
IC50: 10nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Three-prime repair exonuclease 1
(Human)
Constellation Pharmaceuticals
US Patent
Ligand
BDBM708064
((R)-5-hydroxy-2-(2-(2- hydroxyethyl)piperidin-1- y...)
Copy SMILES
Affinity Data
IC50: 10nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Three-prime repair exonuclease 1
(Human)
Constellation Pharmaceuticals
US Patent
Ligand
BDBM708065
((R)-5-hydroxy-N-(isoxazol- 4-yl)-1-methyl-6-oxo-2-...)
Copy SMILES
Affinity Data
IC50: 10nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Three-prime repair exonuclease 1
(Human)
Constellation Pharmaceuticals
US Patent
Ligand
BDBM708066
((S)-5-hydroxy-N-(isoxazol- 4-yl)-1-methyl-6-oxo-2-...)
Copy SMILES
Affinity Data
IC50: 10nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Three-prime repair exonuclease 1
(Human)
Constellation Pharmaceuticals
US Patent
Ligand
BDBM708069
((S)-5-hydroxy-N-(isoxazol- 4-yl)-1-methyl-6-oxo-2-...)
Copy SMILES
Affinity Data
IC50: 10nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Three-prime repair exonuclease 1
(Human)
Constellation Pharmaceuticals
US Patent
Ligand
BDBM708070
((R)-5-hydroxy-N-(isoxazol- 4-yl)-1-methyl-6-oxo-2-...)
Copy SMILES
Affinity Data
IC50: 10nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Three-prime repair exonuclease 1
(Human)
Constellation Pharmaceuticals
US Patent
Ligand
BDBM708073
((R)-2-(3- carbamoylpyrrolidin-1-yl)- 5-hydroxy-N-(...)
Copy SMILES
Affinity Data
IC50: 10nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Three-prime repair exonuclease 1
(Human)
Constellation Pharmaceuticals
US Patent
Ligand
BDBM708075
(5-hydroxy-N-(isoxazol-4- yl)-1-methyl-6-oxo-2- phe...)
Copy SMILES
Affinity Data
IC50: 10nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Three-prime repair exonuclease 1
(Human)
Constellation Pharmaceuticals
US Patent
Ligand
BDBM708076
(2-(cyclohexyloxy)-5- hydroxy-N-(isoxazol-4-yl)- 1-...)
Copy SMILES
Affinity Data
IC50: 10nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Three-prime repair exonuclease 1
(Human)
Constellation Pharmaceuticals
US Patent
Ligand
BDBM708079
((R)-2-(2-(2- chlorophenyl)pyrrolidin-1- yl)-5-hydr...)
Copy SMILES
Affinity Data
IC50: 10nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Three-prime repair exonuclease 1
(Human)
Constellation Pharmaceuticals
US Patent
Ligand
BDBM708080
((S)-2-(2-(2-chlorophenyl)-4- (pyridin-2-yl)piperaz...)
Copy SMILES
Affinity Data
IC50: 10nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Three-prime repair exonuclease 1
(Human)
Constellation Pharmaceuticals
US Patent
Ligand
BDBM708081
((R)-2-(4-acetyl-2-(2- chlorophenyl)piperazin-1- yl...)
Copy SMILES
Affinity Data
IC50: 10nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Three-prime repair exonuclease 1
(Human)
Constellation Pharmaceuticals
US Patent
Ligand
BDBM708084
(1-((2-((R)-1-(3,4-dichlorobenzoyl)piperidin-3-yl)-...)
Copy SMILES
Affinity Data
IC50: 10nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Three-prime repair exonuclease 1
(Human)
Constellation Pharmaceuticals
US Patent
Ligand
BDBM707969
(2-cyclobutyl-5- hydroxy-N-(isoxazol- 4-yl)-1-methy...)
Copy SMILES
Affinity Data
IC50: 55nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Three-prime repair exonuclease 1
(Human)
Constellation Pharmaceuticals
US Patent
Ligand
BDBM707970
(2-cyclopropyl-5- hydroxy-N-(isoxazol- 4-yl)-1-meth...)
Copy SMILES
Affinity Data
IC50: 55nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Three-prime repair exonuclease 1
(Human)
Constellation Pharmaceuticals
US Patent
Ligand
BDBM707971
(2-(5-bromo-2- methylphenyl)-5- hydroxy-N-(isoxazol...)
Copy SMILES
Affinity Data
IC50: 55nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Three-prime repair exonuclease 1
(Human)
Constellation Pharmaceuticals
US Patent
Ligand
BDBM707973
(2-benzyl-5-hydroxy- N-(isoxazol-4-yl)-1- methyl-6-...)
Copy SMILES
Affinity Data
IC50: 55nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Three-prime repair exonuclease 1
(Human)
Constellation Pharmaceuticals
US Patent
Ligand
BDBM707974
(benzyl (1-(5-hydroxy- 4-(isoxazol-4- ylcarbamoyl)-...)
Copy SMILES
Affinity Data
IC50: 55nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Three-prime repair exonuclease 1
(Human)
Constellation Pharmaceuticals
US Patent
Ligand
BDBM707975
(US12172990, Example 8)
Copy SMILES
Affinity Data
IC50: 55nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Three-prime repair exonuclease 1
(Human)
Constellation Pharmaceuticals
US Patent
Ligand
BDBM707976
(2-(2-bromophenyl)-5- hydroxy-N-(isoxazol-4- yl)-1-...)
Copy SMILES
Affinity Data
IC50: 55nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Three-prime repair exonuclease 1
(Human)
Constellation Pharmaceuticals
US Patent
Ligand
BDBM707978
(2-(4-bromophenyl)-5- hydroxy-N-(isoxazol-4- yl)-1-...)
Copy SMILES
Affinity Data
IC50: 55nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Three-prime repair exonuclease 1
(Human)
Constellation Pharmaceuticals
US Patent
Ligand
BDBM707980
(tert-butyl 3-(5-hydroxy- 4-(isoxazol-4- ylcarbamoy...)
Copy SMILES
Affinity Data
IC50: 55nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Three-prime repair exonuclease 1
(Human)
Constellation Pharmaceuticals
US Patent
Ligand
BDBM707981
(tert-butyl 2-(5-hydroxy- 4-(isoxazol-4- ylcarbamoy...)
Copy SMILES
Affinity Data
IC50: 55nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Three-prime repair exonuclease 1
(Human)
Constellation Pharmaceuticals
US Patent
Ligand
BDBM707983
(tert-butyl 3-(5- hydroxy-4-(isoxazol- 4-ylcarbamoy...)
Copy SMILES
Affinity Data
IC50: 55nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Three-prime repair exonuclease 1
(Human)
Constellation Pharmaceuticals
US Patent
Ligand
BDBM707985
(tert-butyl 3-((5- hydroxy-4-(isoxazol- 4-ylcarbamo...)
Copy SMILES
Affinity Data
IC50: 55nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Three-prime repair exonuclease 1
(Human)
Constellation Pharmaceuticals
US Patent
Ligand
BDBM707987
(5-hydroxy-N- (isoxazol-4-yl)-1- methyl-6-oxo-2-(1-...)
Copy SMILES
Affinity Data
IC50: 55nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Three-prime repair exonuclease 1
(Human)
Constellation Pharmaceuticals
US Patent
Ligand
BDBM707990
(benzyl ((5-hydroxy-4- (isoxazol-4- ylcarbamoyl)-1-...)
Copy SMILES
Affinity Data
IC50: 55nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Three-prime repair exonuclease 1
(Human)
Constellation Pharmaceuticals
US Patent
Ligand
BDBM707991
(benzyl ((4- bromophenyl)(5- hydroxy-4-(isoxazol- 4...)
Copy SMILES
Affinity Data
IC50: 55nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Three-prime repair exonuclease 1
(Human)
Constellation Pharmaceuticals
US Patent
Ligand
BDBM707992
(2-(3,5- dimethylphenyl)-5- hydroxy-N-(isoxazol- 4-...)
Copy SMILES
Affinity Data
IC50: 55nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Three-prime repair exonuclease 1
(Human)
Constellation Pharmaceuticals
US Patent
Ligand
BDBM707995
(5-hydroxy-N-(isoxazol-4-yl)-1-methyl-6-oxo-2-(pipe...)
Copy SMILES
Affinity Data
IC50: 55nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Three-prime repair exonuclease 1
(Human)
Constellation Pharmaceuticals
US Patent
Ligand
BDBM707997
(2-(3,5- dichlorophenyl)-5- hydroxy-N-(isoxazol- 4-...)
Copy SMILES
Affinity Data
IC50: 55nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Three-prime repair exonuclease 1
(Human)
Constellation Pharmaceuticals
US Patent
Ligand
BDBM707998
(5-hydroxy-N- (isoxazol-4-yl)-1- methyl-2-(3-methyl...)
Copy SMILES
Affinity Data
IC50: 55nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Three-prime repair exonuclease 1
(Human)
Constellation Pharmaceuticals
US Patent
Ligand
BDBM707999
(5-hydroxy-N- (isoxazol-4-yl)-1- methyl-2-(3-methyl...)
Copy SMILES
Affinity Data
IC50: 55nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Three-prime repair exonuclease 1
(Human)
Constellation Pharmaceuticals
US Patent
Ligand
BDBM708000
(5-hydroxy-N- (isoxazol-4-yl)-1- methyl-2-(3-methyl...)
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Affinity Data
IC50: 55nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
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Target
Three-prime repair exonuclease 1
(Human)
Constellation Pharmaceuticals
US Patent
Ligand
BDBM708001
(5-hydroxy-N- (isoxazol-4-yl)-1- methyl-2-(3-methyl...)
Copy SMILES
Affinity Data
IC50: 55nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Three-prime repair exonuclease 1
(Human)
Constellation Pharmaceuticals
US Patent
Ligand
BDBM708002
(5-hydroxy-N- (isoxazol-4-yl)-1- methyl-2-(3-methyl...)
Copy SMILES
Affinity Data
IC50: 55nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Three-prime repair exonuclease 1
(Human)
Constellation Pharmaceuticals
US Patent
Ligand
BDBM708003
(2-(3- (dimethylcarbamoyl)- 5-methylphenyl)-5- hydr...)
Copy SMILES
Affinity Data
IC50: 55nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
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