Compile Data Set for Download or QSAR
Report error Found 42 of ic50 data for polymerid = 10411
TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandPNGBDBM238166(US9394291, 7 | US10017502, Example 7)
Affinity DataIC50: 9.5nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandPNGBDBM238166(US9394291, 7 | US10017502, Example 7)
Affinity DataIC50: 9.5nMpH: 7.5Assay Description:Test A1: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandPNGBDBM404277(US10017502, Example 8b)
Affinity DataIC50: 10nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandPNGBDBM238167(US9394291, 8b | US9394291, 8a | US9394291, 8 | US1...)
Affinity DataIC50: 10nMpH: 7.5Assay Description:Test A1: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandPNGBDBM404271(US10017502, Example 6a)
Affinity DataIC50: 13nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandPNGBDBM238163(US9394291, 6b | US9394291, 6a | US9394291, 6 | US1...)
Affinity DataIC50: 13nMpH: 7.5Assay Description:Test A1: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandPNGBDBM238161(US9394291, 5a | US10017502, Example 5a)
Affinity DataIC50: 16nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandPNGBDBM238161(US9394291, 5a | US10017502, Example 5a)
Affinity DataIC50: 16nMpH: 7.5Assay Description:Test A1: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandPNGBDBM238167(US9394291, 8b | US9394291, 8a | US9394291, 8 | US1...)
Affinity DataIC50: 40nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandPNGBDBM238167(US9394291, 8b | US9394291, 8a | US9394291, 8 | US1...)
Affinity DataIC50: 40nMpH: 7.5Assay Description:Test A1: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandPNGBDBM238163(US9394291, 6b | US9394291, 6a | US9394291, 6 | US1...)
Affinity DataIC50: 58nMpH: 7.5Assay Description:Test A2: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandPNGBDBM238163(US9394291, 6b | US9394291, 6a | US9394291, 6 | US1...)
Affinity DataIC50: 58nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandPNGBDBM238163(US9394291, 6b | US9394291, 6a | US9394291, 6 | US1...)
Affinity DataIC50: 82nMpH: 7.5Assay Description:Test A1: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandPNGBDBM238163(US9394291, 6b | US9394291, 6a | US9394291, 6 | US1...)
Affinity DataIC50: 82nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandPNGBDBM238159(US9394291, 4a | US10017502, Example 4b)
Affinity DataIC50: 130nMpH: 7.5Assay Description:Test A1: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...More data for this Ligand-Target Pair
In DepthDetails
US Patent
PDB3D3D Structure (crystal)
TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandPNGBDBM404265(US10017502, Example 4a)
Affinity DataIC50: 130nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandPNGBDBM238158(US9394291, 4 | US10017502, Example 4)
Affinity DataIC50: 180nMpH: 7.5Assay Description:Test A1: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandPNGBDBM238158(US9394291, 4 | US10017502, Example 4)
Affinity DataIC50: 180nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandPNGBDBM404258(US10017502, Example 2a)
Affinity DataIC50: 230nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandPNGBDBM238152(US9394291, 2a | US9394291, 2 | US10017502, Example...)
Affinity DataIC50: 230nMpH: 7.5Assay Description:Test A1: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandPNGBDBM238159(US9394291, 4a | US10017502, Example 4b)
Affinity DataIC50: 240nMpH: 7.5Assay Description:Test A2: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...More data for this Ligand-Target Pair
In DepthDetails
US Patent
PDB3D3D Structure (crystal)
TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandPNGBDBM404265(US10017502, Example 4a)
Affinity DataIC50: 240nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandPNGBDBM238155(US9394291, 3b | US9394291, 3 | US10017502, Example...)
Affinity DataIC50: 270nMpH: 7.5Assay Description:Test A1: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandPNGBDBM404263(2-{(3S or 3R)-7-Fluoro-4-[(3-oxo-3,4-dihydro-2H-1,...)
Affinity DataIC50: 270nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandPNGBDBM238155(US9394291, 3b | US9394291, 3 | US10017502, Example...)
Affinity DataIC50: 480nMpH: 7.5Assay Description:Test A1: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandPNGBDBM238155(US9394291, 3b | US9394291, 3 | US10017502, Example...)
Affinity DataIC50: 480nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandPNGBDBM238158(US9394291, 4 | US10017502, Example 4)
Affinity DataIC50: 740nMpH: 7.5Assay Description:Test A2: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandPNGBDBM238158(US9394291, 4 | US10017502, Example 4)
Affinity DataIC50: 740nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandPNGBDBM238151(US9394291, 1 | US10017502, Example 1)
Affinity DataIC50: 1.40E+3nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandPNGBDBM238151(US9394291, 1 | US10017502, Example 1)
Affinity DataIC50: 1.40E+3nMpH: 7.5Assay Description:Test A1: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandPNGBDBM404276(US10017502, Example 8a)
Affinity DataIC50: 1.60E+3nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandPNGBDBM238167(US9394291, 8b | US9394291, 8a | US9394291, 8 | US1...)
Affinity DataIC50: 1.60E+3nMpH: 7.5Assay Description:Test A1: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandPNGBDBM238152(US9394291, 2a | US9394291, 2 | US10017502, Example...)
Affinity DataIC50: 1.80E+3nMpH: 7.5Assay Description:Test A2: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandPNGBDBM238152(US9394291, 2a | US9394291, 2 | US10017502, Example...)
Affinity DataIC50: 1.80E+3nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandPNGBDBM238163(US9394291, 6b | US9394291, 6a | US9394291, 6 | US1...)
Affinity DataIC50: 1.90E+3nMpH: 7.5Assay Description:Test A1: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandPNGBDBM404273(US10017502, Example 6b)
Affinity DataIC50: 1.90E+3nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandPNGBDBM238151(US9394291, 1 | US10017502, Example 1)
Affinity DataIC50: 2.90E+3nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandPNGBDBM238151(US9394291, 1 | US10017502, Example 1)
Affinity DataIC50: 2.90E+3nMpH: 7.5Assay Description:Test A2: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandPNGBDBM238162(US9394291, 5b | US10017502, Example 5b)
Affinity DataIC50: 4.90E+3nMpH: 7.5Assay Description:Test A1: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandPNGBDBM238162(US9394291, 5b | US10017502, Example 5b)
Affinity DataIC50: 4.90E+3nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandPNGBDBM238159(US9394291, 4a | US10017502, Example 4b)
Affinity DataIC50: 3.75E+4nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
In DepthDetails
US Patent
PDB3D3D Structure (crystal)
TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandPNGBDBM404262(2-{(3S or 3R)-7-Fluoro-4-[(3-oxo-3,4-dihydro-2H-1,...)
Affinity DataIC50: 3.75E+4nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent