Compile Data Set for Download or QSAR
Report error Found 285 of ic50 data for polymerid = 10249
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50234990(CHEMBL4062453)
Affinity DataIC50: 1nMAssay Description:Inhibition of N-terminal His6-tagged full-length recombinant human NEK2 expressed in baculovirus infected sf21 cells using biotin labelled-STK-3 subs...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50234994(CHEMBL4063211)
Affinity DataIC50: 3nMAssay Description:Inhibition of N-terminal His6-tagged full-length recombinant human NEK2 expressed in baculovirus infected sf21 cells using biotin labelled-STK-3 subs...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50574084(CHEMBL4860697)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of NEK2 (unknown origin) using 5' FAM-KKLNRTLSVA-COOH peptide as a substrate in the presence of ATP incubated for 60 mins by microfluidics...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50235015(CHEMBL4091089)
Affinity DataIC50: 7nMAssay Description:Inhibition of N-terminal His6-tagged full-length recombinant human NEK2 expressed in baculovirus infected sf21 cells using biotin labelled-STK-3 subs...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50553212(CHEMBL4763380)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant full length His-tagged NEK2 expressed in baculovirus expression system assessed as inhibition of substrate phosphoryl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50553217(CHEMBL4761747)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant full length His-tagged NEK2 expressed in baculovirus expression system assessed as inhibition of substrate phosphoryl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50381716(US8722890, 1 | US8722890, 2 | ABT-348 | ILORASERTI...)
Affinity DataIC50: 13nMAssay Description:Inhibition of NEK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50553207(CHEMBL4786783)
Affinity DataIC50: 18nMAssay Description:Inhibition of human NEK2 by kinase-profiling analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50347865(CHEMBL1802383)
Affinity DataIC50: 20nMAssay Description:Inhibition of human Nek2 in using [gamma-32P] ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50385915(CHEMBL2042135)
Affinity DataIC50: 22nMAssay Description:Inhibition of Nek2 using 5-FAM-KKLNRTLSVA-COOH as substrate after 1 hr by caliper methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM28216(5-{6-[(1-methylpiperidin-4-yl)oxy]-1H-1,3-benzodia...)
Affinity DataIC50: 25nMAssay Description:Inhibition of NEK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50553200(CHEMBL4796125)
Affinity DataIC50: 26nMAssay Description:Inhibition of human recombinant full length His-tagged NEK2 expressed in baculovirus expression system assessed as inhibition of substrate phosphoryl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50385916(CHEMBL2042136)
Affinity DataIC50: 37nMAssay Description:Inhibition of Nek2 using 5-FAM-KKLNRTLSVA-COOH as substrate after 1 hr by caliper methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50553205(CHEMBL4743876)
Affinity DataIC50: 39nMAssay Description:Inhibition of human recombinant full length His-tagged NEK2 expressed in baculovirus expression system assessed as inhibition of substrate phosphoryl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50613378(CHEMBL1997822)
Affinity DataIC50: 40nMAssay Description:Inhibition of NEK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50553213(CHEMBL4779487)
Affinity DataIC50: 42nMAssay Description:Inhibition of human recombinant full length His-tagged NEK2 expressed in baculovirus expression system assessed as inhibition of substrate phosphoryl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50385922(CHEMBL2042035)
Affinity DataIC50: 47nMAssay Description:Inhibition of Nek2 using 5-FAM-KKLNRTLSVA-COOH as substrate after 1 hr by caliper methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50385923(CHEMBL2042036)
Affinity DataIC50: 47nMAssay Description:Inhibition of Nek2 using 5-FAM-KKLNRTLSVA-COOH as substrate after 1 hr by caliper methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM28216(5-{6-[(1-methylpiperidin-4-yl)oxy]-1H-1,3-benzodia...)
Affinity DataIC50: 50nMAssay Description:Inhibition of NEK2 autophosphorylation preincubated with compound by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50553201(CHEMBL4775990)
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant full length His-tagged NEK2 expressed in baculovirus expression system assessed as inhibition of substrate phosphoryl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM121388(US8722890, 3)
Affinity DataIC50: 50nMAssay Description:Inhibition of NEK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50553198(CHEMBL4796754)
Affinity DataIC50: 57nMAssay Description:Inhibition of human recombinant full length His-tagged NEK2 expressed in baculovirus expression system assessed as inhibition of substrate phosphoryl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50553215(CHEMBL4783060)
Affinity DataIC50: 57nMAssay Description:Inhibition of human recombinant full length His-tagged NEK2 expressed in baculovirus expression system assessed as inhibition of substrate phosphoryl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50385924(CHEMBL2042037)
Affinity DataIC50: 58nMAssay Description:Inhibition of Nek2 using 5-FAM-KKLNRTLSVA-COOH as substrate after 1 hr by caliper methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50385916(CHEMBL2042136)
Affinity DataIC50: 59nMAssay Description:Inhibition of Nek2 using 5-FAM-KKLNRTLSVA-COOH as substrate after 1 hr by caliper methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50347864(CHEMBL1802382)
Affinity DataIC50: 60nMAssay Description:Inhibition of human Nek2 in using [gamma-32P] ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50553207(CHEMBL4786783)
Affinity DataIC50: 62nMAssay Description:Inhibition of human recombinant full length His-tagged NEK2 expressed in baculovirus expression system assessed as inhibition of substrate phosphoryl...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50553204(CHEMBL4748191)
Affinity DataIC50: 64nMAssay Description:Inhibition of human recombinant full length His-tagged NEK2 expressed in baculovirus expression system assessed as inhibition of substrate phosphoryl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50553199(CHEMBL4795738)
Affinity DataIC50: 71nMAssay Description:Inhibition of human recombinant full length His-tagged NEK2 expressed in baculovirus expression system assessed as inhibition of substrate phosphoryl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50553197(CHEMBL4746054)
Affinity DataIC50: 72nMAssay Description:Inhibition of human recombinant full length His-tagged NEK2 expressed in baculovirus expression system assessed as inhibition of substrate phosphoryl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50385914(CHEMBL2042042)
Affinity DataIC50: 73nMAssay Description:Inhibition of Nek2 using 5-FAM-KKLNRTLSVA-COOH as substrate after 1 hr by caliper methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50553196(CHEMBL4783265)
Affinity DataIC50: 76nMAssay Description:Inhibition of human recombinant full length His-tagged NEK2 expressed in baculovirus expression system assessed as inhibition of substrate phosphoryl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50553214(CHEMBL4776787)
Affinity DataIC50: 76nMAssay Description:Inhibition of human recombinant full length His-tagged NEK2 expressed in baculovirus expression system assessed as inhibition of substrate phosphoryl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50553195(CHEMBL4746829)
Affinity DataIC50: 79nMAssay Description:Inhibition of human recombinant full length His-tagged NEK2 expressed in baculovirus expression system assessed as inhibition of substrate phosphoryl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50235007(CHEMBL4087758)
Affinity DataIC50: 87nMAssay Description:Inhibition of N-terminal His6-tagged full-length recombinant human NEK2 expressed in baculovirus infected sf21 cells using biotin labelled-STK-3 subs...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50553209(CHEMBL4761123)
Affinity DataIC50: 88nMAssay Description:Inhibition of human recombinant full length His-tagged NEK2 expressed in baculovirus expression system assessed as inhibition of substrate phosphoryl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50385928(CHEMBL2042038)
Affinity DataIC50: 93nMAssay Description:Inhibition of Nek2 using 5-FAM-KKLNRTLSVA-COOH as substrate after 1 hr by caliper methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50553208(CHEMBL4776060)
Affinity DataIC50: 93nMAssay Description:Inhibition of human recombinant full length His-tagged NEK2 expressed in baculovirus expression system assessed as inhibition of substrate phosphoryl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50335188(CHEMBL1650551 | CHEMBL1650545 | N-[3-[(3,3-Difluor...)
Affinity DataIC50: 100nMAssay Description:Inhibition of NEK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50329198(CHEMBL1650533 | 2-{ethyl[(5-{[6-methyl-3-(1H-pyraz...)
Affinity DataIC50: 100nMAssay Description:Inhibition of NEK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50335188(CHEMBL1650551 | CHEMBL1650545 | N-[3-[(3,3-Difluor...)
Affinity DataIC50: 100nMAssay Description:Inhibition of NEK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50553210(CHEMBL4754015)
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant full length His-tagged NEK2 expressed in baculovirus expression system assessed as inhibition of substrate phosphoryl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50553202(CHEMBL4753609)
Affinity DataIC50: 110nMAssay Description:Inhibition of human recombinant full length His-tagged NEK2 expressed in baculovirus expression system assessed as inhibition of substrate phosphoryl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50553203(CHEMBL4756141)
Affinity DataIC50: 110nMAssay Description:Inhibition of human recombinant full length His-tagged NEK2 expressed in baculovirus expression system assessed as inhibition of substrate phosphoryl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50553194(CHEMBL4759854)
Affinity DataIC50: 116nMAssay Description:Inhibition of human recombinant full length His-tagged NEK2 expressed in baculovirus expression system assessed as inhibition of substrate phosphoryl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50385919(CHEMBL2042031)
Affinity DataIC50: 120nMAssay Description:Inhibition of Nek2 using 5-FAM-KKLNRTLSVA-COOH as substrate after 1 hr by caliper methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50347866(CHEMBL1802384)
Affinity DataIC50: 130nMAssay Description:Inhibition of human Nek2 in using [gamma-32P] ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50553216(CHEMBL4754958)
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant full length His-tagged NEK2 expressed in baculovirus expression system assessed as inhibition of substrate phosphoryl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50235350(CHEMBL4094562)
Affinity DataIC50: 140nMAssay Description:Inhibition of human recombinant full length His-tagged NEK2 expressed in baculovirus expression system assessed as inhibition of substrate phosphoryl...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50235361(CHEMBL4074015)
Affinity DataIC50: 140nMAssay Description:Inhibition of human recombinant full length His-tagged NEK2 expressed in baculovirus expression system assessed as inhibition of substrate phosphoryl...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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