Compile Data Set for Download or QSAR
Report error Found 25 of ic50 data for polymerid = 10232
TargetTyrosine-protein kinase Fes/Fps(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50242740(Type II inhibitor, 14 | CHEMBL459850 | N-(3-(7-Ami...)
Affinity DataIC50: 1nMAssay Description:Inhibition of FesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Fes/Fps(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human FES using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Fes/Fps(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human FES using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Fes/Fps(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50577169(CHEMBL4846921)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of Fes (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Fes/Fps(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50448785(CHEMBL3128069)
Affinity DataIC50: 5nMAssay Description:Inhibition of FES (unknown origin) using Km levels of ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Fes/Fps(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50018830(CHEMBL3286830 | US10543199, Compound PF-06463922 |...)
Affinity DataIC50: 6nMAssay Description:Inhibition of FES (unknown origin) by TR-FRET-based Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Fes/Fps(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 8.10nMAssay Description:Inhibition of FES (unknown origin) incubated for 1 hr by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Fes/Fps(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50389154(CHEMBL2064666)
Affinity DataIC50: 99nMAssay Description:Inhibition of human FesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Fes/Fps(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50584720(CHEMBL5088153)
Affinity DataIC50: 269nMAssay Description:Inhibition of human FES in presence of ATP by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Fes/Fps(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 358nMAssay Description:Inhibition of FESMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Fes/Fps(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50515040(CHEMBL4474361)
Affinity DataIC50: 494nMAssay Description:Inhibition of FES (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Fes/Fps(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50515041(CHEMBL4125960)
Affinity DataIC50: 527nMAssay Description:Inhibition of FES (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Fes/Fps(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM482158(TAE684 | BDBM50242742)
Affinity DataIC50: 569nMAssay Description:Inhibition of FES (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase Fes/Fps(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50429867(CHEMBL2333365)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FES (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Fes/Fps(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50336316(cis-3-(3-(azetidin-1-ylmethyl)cyclobutyl)-1-(2-phe...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FESMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Fes/Fps(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50401152(CHEMBL2205766)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FESMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Fes/Fps(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50499634(CHEMBL3741589)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FES (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Fes/Fps(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50519662(CHEMBL4438748)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human FES (2 to end residues) using poly(Glu, Tyr) 4:1 as substrate after 40 mins in presence of [gamma-33ATP] by radiometr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Fes/Fps(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50135286(CHEMBL3745885)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human FES using poly[Glu:Tyr] (4:1) as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Fes/Fps(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant FesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Fes/Fps(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM236557(US9365572, 5)
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:Agents: 1-fold kinase buffer without MnCl2: 50 mM HEPES, pH 7.5, 0.0015% Brij-35, 10 mM MgCl2, 2 mM DTT. 1-fold kinase buffer with MnCl2: 50 mM HEPES...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetTyrosine-protein kinase Fes/Fps(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM13533(1-[5-tert-butyl-2-(p-tolyl)pyrazol-3-yl]-3-[4-(2-m...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of FESMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Fes/Fps(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50359359(CHEMBL1929238)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of FESMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Fes/Fps(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50182493(CHEMBL3818247 | US9512121, 22)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of FES (unknown origin) incubated for 1 hr by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Fes/Fps(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant His-tagged full length human FES expressed in baculovirus expression system using Tyr 01 peptide as substrate after 1 hr by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed