Compile Data Set for Download or QSAR
Report error Found 572 of ic50 data for polymerid = 10033
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255710(CHEMBL4091258)
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human N-terminal His-tagged SIRT5 (34 to 269 residues) expressed in Escherichia coli Transetta(DE3) cells using Benzyl Lys(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255714(CHEMBL4064460)
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant human N-terminal His-tagged SIRT5 (34 to 269 residues) expressed in Escherichia coli Transetta(DE3) cells using Benzyl Lys(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255700(CHEMBL4091790)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant N-terminal Strep2-tagged SIRT5 expressed in Escherichia coli BL21 (DE3) using Abz-GVLK(glutaryl)AY(NO2)GV-NH2 as subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255700(CHEMBL4091790)
Affinity DataIC50: 30nMAssay Description:Inhibition of SIRT5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255635(CHEMBL4065953)
Affinity DataIC50: 46nMAssay Description:Inhibition of recombinant human N-terminal His-tagged SIRT5 (34 to 269 residues) expressed in Escherichia coli Transetta(DE3) cells using Benzyl Lys(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255740(CHEMBL4100351)
Affinity DataIC50: 46nMAssay Description:Inhibition of human recombinant N-terminal Strep2-tagged SIRT5 expressed in Escherichia coli BL21 (DE3) using Abz-GVLK(glutaryl)AY(NO2)GV-NH2 as subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255711(CHEMBL4083471)
Affinity DataIC50: 59nMAssay Description:Inhibition of recombinant human N-terminal His-tagged SIRT5 (34 to 269 residues) expressed in Escherichia coli Transetta(DE3) cells using Benzyl Lys(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255743(CHEMBL4084850)
Affinity DataIC50: 86nMAssay Description:Inhibition of recombinant human N-terminal His-tagged SIRT5 (34 to 269 residues) expressed in Escherichia coli Transetta(DE3) cells using Benzyl Lys(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255774(CHEMBL4101463)
Affinity DataIC50: 90nMAssay Description:Inhibition of recombinant human N-terminal His-tagged SIRT5 (34 to 269 residues) expressed in Escherichia coli Transetta(DE3) cells using Benzyl Lys(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255726(CHEMBL4085990)
Affinity DataIC50: 91nMAssay Description:Inhibition of human recombinant N-terminal Strep2-tagged SIRT5 expressed in Escherichia coli BL21 (DE3) using Abz-GVLK(glutaryl)AY(NO2)GV-NH2 as subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255701(CHEMBL4079616)
Affinity DataIC50: 95nMAssay Description:Inhibition of recombinant human N-terminal His-tagged SIRT5 (34 to 269 residues) expressed in Escherichia coli Transetta(DE3) cells using Benzyl Lys(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50041802(CHEMBL46469 | 1,8-dihydroxyanthrone | 1,8-dihydrox...)
Affinity DataIC50: 100nMAssay Description:Inhibition of SIRT5 (unknown origin) using GGQSLK[succ]FGKG as substrate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50041802(CHEMBL46469 | 1,8-dihydroxyanthrone | 1,8-dihydrox...)
Affinity DataIC50: 100nMAssay Description:Inhibition of SIRT5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255741(CHEMBL4078223)
Affinity DataIC50: 102nMAssay Description:Inhibition of recombinant human N-terminal His-tagged SIRT5 (34 to 269 residues) expressed in Escherichia coli Transetta(DE3) cells using Benzyl Lys(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50540057(CHEMBL4636862)
Affinity DataIC50: 110nMAssay Description:Inhibition of SIRT5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50540057(CHEMBL4636862)
Affinity DataIC50: 110nMAssay Description:Inhibition of SIRT5 deglutarylase activity (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50595086(CHEMBL5177283)
Affinity DataIC50: 110nMAssay Description:Inhibition of SIRT5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50540057(CHEMBL4636862)
Affinity DataIC50: 110nMAssay Description:Inhibition of human SIRT5More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255639(CHEMBL4097208)
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant human N-terminal His-tagged SIRT5 (34 to 269 residues) expressed in Escherichia coli Transetta(DE3) cells using Benzyl Lys(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255659(CHEMBL4092610)
Affinity DataIC50: 177nMAssay Description:Inhibition of recombinant human N-terminal His-tagged SIRT5 (34 to 269 residues) expressed in Escherichia coli Transetta(DE3) cells using Benzyl Lys(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255703(CHEMBL4063400)
Affinity DataIC50: 207nMAssay Description:Inhibition of recombinant human N-terminal His-tagged SIRT5 (34 to 269 residues) expressed in Escherichia coli Transetta(DE3) cells using Benzyl Lys(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50626459(CHEMBL5398650)
Affinity DataIC50: 210nMAssay Description:Inhibition of human SIRT5 by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50626459(CHEMBL5398650)
Affinity DataIC50: 210nMAssay Description:Inhibition of human SIRT5 in presence of 200 uM NAD+ by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50626459(CHEMBL5398650)
Affinity DataIC50: 210nMAssay Description:Inhibition of human SIRT5 in presence of 10 uM Ac-K(Suc)-AMC by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50595086(CHEMBL5177283)
Affinity DataIC50: 230nMAssay Description:Inhibition of SIRT5 deglutarylase activity (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50626459(CHEMBL5398650)
Affinity DataIC50: 240nMAssay Description:Inhibition of human SIRT5 in presence of 400 uM NAD+ by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50626459(CHEMBL5398650)
Affinity DataIC50: 250nMAssay Description:Inhibition of human SIRT5 in presence of 800 uM NAD+ by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50595085(CHEMBL5197912)
Affinity DataIC50: 260nMAssay Description:Inhibition of SIRT5 deglutarylase activity (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50626459(CHEMBL5398650)
Affinity DataIC50: 260nMAssay Description:Inhibition of human SIRT5 in presence of 100 uM NAD+ by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50626459(CHEMBL5398650)
Affinity DataIC50: 260nMAssay Description:Inhibition of human SIRT5 in presence of 50 uM NAD+ by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255644(CHEMBL4079212)
Affinity DataIC50: 274nMAssay Description:Inhibition of recombinant human N-terminal His-tagged SIRT5 (34 to 269 residues) expressed in Escherichia coli Transetta(DE3) cells using Benzyl Lys(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50598637(CHEMBL5185695)
Affinity DataIC50: 290nMAssay Description:Inhibition of SIRT5 deglutarylase activity (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255651(CHEMBL4093875)
Affinity DataIC50: 295nMAssay Description:Inhibition of recombinant human N-terminal His-tagged SIRT5 (34 to 269 residues) expressed in Escherichia coli Transetta(DE3) cells using Benzyl Lys(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50595085(CHEMBL5197912)
Affinity DataIC50: 300nMAssay Description:Inhibition of SIRT5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50540057(CHEMBL4636862)
Affinity DataIC50: 300nMAssay Description:Inhibition of SIRT5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50627813(CHEMBL5416344)
Affinity DataIC50: 310nMAssay Description:Inhibition of human SIRT5 (34 to 269 residues) using Ac-Leu-Gly-Ser-Lys (Su)-AMC as fluorogenic substrate in presence of NAD+More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255665(CHEMBL4073959)
Affinity DataIC50: 326nMAssay Description:Inhibition of recombinant human N-terminal His-tagged SIRT5 (34 to 269 residues) expressed in Escherichia coli Transetta(DE3) cells using Benzyl Lys(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255668(CHEMBL4086401)
Affinity DataIC50: 336nMAssay Description:Inhibition of recombinant human N-terminal His-tagged SIRT5 (34 to 269 residues) expressed in Escherichia coli Transetta(DE3) cells using Benzyl Lys(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50598633(CHEMBL5182606)
Affinity DataIC50: 340nMAssay Description:Inhibition of SIRT5 desuccinylase activity (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50626459(CHEMBL5398650)
Affinity DataIC50: 340nMAssay Description:Inhibition of human SIRT5 in presence of 30 uM Ac-K(Suc)-AMC by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50598633(CHEMBL5182606)
Affinity DataIC50: 340nMAssay Description:Inhibition of human SIRT5More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255716(CHEMBL4080031)
Affinity DataIC50: 350nMAssay Description:Inhibition of recombinant human N-terminal His-tagged SIRT5 (34 to 269 residues) expressed in Escherichia coli Transetta(DE3) cells using Benzyl Lys(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255750(CHEMBL4104295)
Affinity DataIC50: 352nMAssay Description:Inhibition of recombinant human N-terminal His-tagged SIRT5 (34 to 269 residues) expressed in Escherichia coli Transetta(DE3) cells using Benzyl Lys(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50598634(CHEMBL5188575)
Affinity DataIC50: 370nMAssay Description:Inhibition of SIRT5 deglutarylase activity (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50595088(CHEMBL5201717)
Affinity DataIC50: 390nMAssay Description:Inhibition of SIRT5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50595087(CHEMBL5192844)
Affinity DataIC50: 420nMAssay Description:Inhibition of SIRT5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255684(CHEMBL4100041)
Affinity DataIC50: 432nMAssay Description:Inhibition of recombinant human N-terminal His-tagged SIRT5 (34 to 269 residues) expressed in Escherichia coli Transetta(DE3) cells using Benzyl Lys(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50595076(CHEMBL5209009)
Affinity DataIC50: 450nMAssay Description:Inhibition of GST-tagged SIRT5 (unknown origin) incubated for 10 mins by HPLC based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50595092(CHEMBL5182719)
Affinity DataIC50: 450nMAssay Description:Inhibition of SIRT5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50595091(CHEMBL5195052)
Affinity DataIC50: 500nMAssay Description:Inhibition of SIRT5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
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