Compile Data Set for Download or QSAR
Report error Found 16 of ic50 data for complexid = 50000975,50002883
LigandPNGBDBM50575331(CHEMBL4868242)
Affinity DataIC50: 76nMAssay Description:Inhibition of Orai1/STIM1 (unknown origin) expressed in HEK293 cells assessed as reduction in Ca2+-release activated Ca2+ entry current by manual pat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50575336(CHEMBL4753998)
Affinity DataIC50: 119nMAssay Description:Inhibition of Orai1/STIM1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50549365(CHEMBL3403742)
Affinity DataIC50: 228nMAssay Description:Inhibition of STIM1/Orai1 (unknown origin) expressed in HEK293 cells assessed as reduction in tBHQ-induced calcium responseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50549358(CHEMBL4753023)
Affinity DataIC50: 361nMAssay Description:Inhibition of STIM1/Orai1 (unknown origin) expressed in HEK293 cells assessed as reduction in tBHQ-induced calcium responseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCalcium release-activated calcium channel protein/Stromal interaction molecule 1(Rat)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50204544(CHEMBL262766)
Affinity DataIC50: 590nMAssay Description:Inhibition of ORAI/STIM1 in thapsigargin treated rat RBL2H3 cells assessed as reduction in store-operated calcium entry after 5 mins by fura-2-AM dye...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50549357(CHEMBL4794288)
Affinity DataIC50: 781nMAssay Description:Inhibition of STIM1/Orai1 (unknown origin) expressed in HEK293 cells assessed as reduction in tBHQ-induced calcium responseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50549360(CHEMBL4780000)
Affinity DataIC50: 802nMAssay Description:Inhibition of STIM1/Orai1 (unknown origin) expressed in HEK293 cells assessed as reduction in tBHQ-induced calcium responseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50549363(CHEMBL4751678)
Affinity DataIC50: 807nMAssay Description:Inhibition of STIM1/Orai1 (unknown origin) expressed in HEK293 cells assessed as reduction in tBHQ-induced calcium responseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50549362(CHEMBL4761656)
Affinity DataIC50: 851nMAssay Description:Inhibition of STIM1/Orai1 (unknown origin) expressed in HEK293 cells assessed as reduction in tBHQ-induced calcium responseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50549356(CHEMBL4799904)
Affinity DataIC50: 866nMAssay Description:Inhibition of STIM1/Orai1 (unknown origin) expressed in HEK293 cells assessed as reduction in tBHQ-induced calcium responseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50575334(CHEMBL4863881)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Orai1/STIM1 (unknown origin) expressed in HEK293 cells assessed as reduction in Ca2+-release activated Ca2+ entry current by manual pat...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50549359(CHEMBL4750981)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of STIM1/Orai1 (unknown origin) expressed in HEK293 cells assessed as reduction in tBHQ-induced calcium responseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50549361(CHEMBL4742227)
Affinity DataIC50: 1.62E+3nMAssay Description:Inhibition of STIM1/Orai1 (unknown origin) expressed in HEK293 cells assessed as reduction in tBHQ-induced calcium responseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50549364(CHEMBL4742960)
Affinity DataIC50: 1.79E+3nMAssay Description:Inhibition of STIM1/Orai1 (unknown origin) expressed in HEK293 cells assessed as reduction in tBHQ-induced calcium responseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50575335(CHEMBL4570175)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human STIM1/Orai1 expressed in HEK293 cells assessed as reduction in Orai1 current by electrophysiological methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50018011(CHEBI:68540 | HMR-1726 | Aubagio | TERIFLUNOMIDE)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of STIM1/Orai1 (unknown origin) expressed in HEK293 cells assessed as reduction in tBHQ-induced calcium responseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed