Compile Data Set for Download or QSAR
Report error Found 63 of ic50 data for complexid = 50000902
LigandPNGBDBM50015800(CHEMBL310041 | Diethyl-(1-ethyl-[1,2,4]triazolo[4,...)
Affinity DataIC50: 100nMAssay Description:Evaluated for Ca++ dependent phosphodiesterase activity.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM15336(1-methyl-3-(2-methylpropyl)-2,3,6,7-tetrahydro-1H-...)
Affinity DataIC50: 100nMAssay Description:Evaluated for Ca++ dependent phosphodiesterase activity. More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50287545(4-[4-Ethoxy-3-(1-methyl-7-oxo-3-propyl-6,7-dihydro...)
Affinity DataIC50: 110nMAssay Description:Inhibition of Phosphodiesterase 1 from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 260nMAssay Description:Inhibition of Phosphodiesterase 1 from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against rat heart Phosphodiesterase 1(PDE1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50287543(5-[2-Ethoxy-5-(piperazine-1-sulfonyl)-phenyl]-1-me...)
Affinity DataIC50: 390nMAssay Description:Inhibition of Phosphodiesterase 1 from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50287550(5-{2-Ethoxy-5-[4-(2-hydroxy-ethyl)-piperazine-1-su...)
Affinity DataIC50: 460nMAssay Description:Inhibition of Phosphodiesterase 1 from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50100673(methyl 2-(4-aminophenyl)-4-(4-bromo-3,5-dimethoxyp...)
Affinity DataIC50: 460nMAssay Description:Inhibitory activity against rat heart Phosphodiesterase 1(PDE1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50100668(ethyl 2-(4-aminophenyl)-1-oxo-7-(2-pyridylmethoxy)...)
Affinity DataIC50: 550nMAssay Description:Inhibitory activity against rat heart Phosphodiesterase 1(PDE1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50111899(5-(2-ethoxyphenyl)-1-methyl-3-propyl-1H-pyrazolo[4...)
Affinity DataIC50: 790nMAssay Description:Inhibition of Phosphodiesterase 1 from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50169640(5-(2-Ethoxy-phenyl)-3-propyl-1,6-dihydro-pyrazolo[...)
Affinity DataIC50: 860nMAssay Description:Inhibition of Phosphodiesterase 1 from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50100667(2-(4-Amino-phenyl)-7-methoxy-1-oxo-4-(3,4,5-trimet...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against rat heart Phosphodiesterase 1(PDE1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50015773(CHEMBL311616 | (8-Chloro-1-trifluoromethyl-[1,2,4]...)
Affinity DataIC50: 1.00E+3nMAssay Description:Evaluated for Ca++ dependent phosphodiesterase activity.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50100674(methyl 2-(4-aminophenyl)-4-(3,5-dimethoxy-4-methyl...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory activity against rat heart Phosphodiesterase 1(PDE1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50015780(CHEMBL7033 | cid_654516 | Diethyl-[1,2,4]triazolo[...)
Affinity DataIC50: 1.20E+3nMAssay Description:Evaluated for Ca++ dependent phosphodiesterase activity.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50100662(CHEMBL77971 | CHEMBL553371 | methyl 2-(4-aminophen...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibitory activity against rat heart Phosphodiesterase 1(PDE1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50015771(CHEMBL72052 | 1-Ethyl-[1,2,4]triazolo[4,3-a]quinox...)
Affinity DataIC50: 2.00E+3nMAssay Description:Evaluated for Ca++ dependent phosphodiesterase activity.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50015752(CHEMBL72177 | (8-Chloro-1-ethyl-[1,2,4]triazolo[4,...)
Affinity DataIC50: 2.00E+3nMAssay Description:Evaluated for Ca++ dependent phosphodiesterase activity.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50100666(6,7-Dimethoxy-2-methyl-1-oxo-4-(3,4,5-trimethoxy-p...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibitory activity against rat heart Phosphodiesterase 1(PDE1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50100656(2-(4-Amino-phenyl)-7-benzyloxy-1-oxo-4-(3,4,5-trim...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibitory activity against rat heart Phosphodiesterase 1(PDE1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50100678(2-(4-Amino-phenyl)-4-(4-hydroxy-3,5-dimethoxy-phen...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibitory activity against rat heart Phosphodiesterase 1(PDE1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50015757(CHEMBL73152 | 4-Piperazin-1-yl-[1,2,4]triazolo[4,3...)
Affinity DataIC50: 3.00E+3nMAssay Description:Evaluated for Ca++ dependent phosphodiesterase activity.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50015749(CHEMBL6958 | (1-Ethyl-[1,2,4]triazolo[4,3-a]quinox...)
Affinity DataIC50: 3.00E+3nMAssay Description:Evaluated for Ca++ dependent phosphodiesterase activity.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50100655(2-Benzyl-6,7-dimethoxy-1-oxo-4-(3,4,5-trimethoxy-p...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibitory activity against rat heart Phosphodiesterase 1(PDE1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50287546(5-(2-Ethoxy-phenyl)-1,3-dimethyl-1,6-dihydro-pyraz...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of Phosphodiesterase 1 from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50100653(2-(4-Amino-phenyl)-6-methoxy-1-oxo-4-(3,4,5-trimet...)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibitory activity against rat heart Phosphodiesterase 1(PDE1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50100659(methyl 2-(4-aminophenyl)-1-oxo-7-(3-pyridylmethoxy...)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibitory activity against rat heart Phosphodiesterase 1(PDE1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM14363(5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of Phosphodiesterase 1 from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50100670(methyl 2-(4-aminophenyl)-1-oxo-7-(4-pyridylmethoxy...)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibitory activity against rat heart Phosphodiesterase 1(PDE1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50015803(CHEMBL73478 | (8-Chloro-1-trifluoromethyl-[1,2,4]t...)
Affinity DataIC50: 1.00E+4nMAssay Description:Evaluated for Ca++ dependent phosphodiesterase activity. More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50100657(6,7-Dimethoxy-1-oxo-4-(3,4,5-trimethoxy-phenyl)-1,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against rat heart Phosphodiesterase 1(PDE1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50100658(2-(3-Amino-phenyl)-6,7-dimethoxy-1-oxo-4-(3,4,5-tr...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against rat heart Phosphodiesterase 1(PDE1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50015770(CHEMBL306351 | Cyclohexyl-(8-fluoro-1-trifluoromet...)
Affinity DataIC50: 1.00E+4nMAssay Description:Evaluated for Ca++ dependent phosphodiesterase activity. More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50015769(CHEMBL73039 | 8-Fluoro-[1,2,4]triazolo[4,3-a]quino...)
Affinity DataIC50: 1.00E+4nMAssay Description:Evaluated for Ca++ dependent phosphodiesterase activity.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50100663(methyl 2-(4-aminophenyl)-4-(3-hydroxy-4,5-dimethox...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against rat heart Phosphodiesterase 1(PDE1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50015798(CHEMBL307187 | 8-Chloro-1-trifluoromethyl-[1,2,4]t...)
Affinity DataIC50: 1.00E+4nMAssay Description:Evaluated for Ca++ dependent phosphodiesterase activity.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50015764(CHEMBL302511 | (8-Chloro-1-phenyl-[1,2,4]triazolo[...)
Affinity DataIC50: 1.00E+4nMAssay Description:Evaluated for Ca++ dependent phosphodiesterase activity. More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50228563(CHEMBL428502)
Affinity DataIC50: 1.00E+4nMAssay Description:Evaluated for Ca++ dependent phosphodiesterase activity.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50100679(6,7-Dimethoxy-2-morpholin-4-yl-1-oxo-4-(3,4,5-trim...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against rat heart Phosphodiesterase 1(PDE1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50100661(2-(4-Hydroxy-phenyl)-6,7-dimethoxy-1-oxo-4-(3,4,5-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against rat heart Phosphodiesterase 1(PDE1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50100675(3N,3N-dimethyl-2-(4-aminophenyl)-1-oxo-7-(2-pyridy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against rat heart Phosphodiesterase 1(PDE1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50100660(6,7-Dimethoxy-1-oxo-2-phenyl-4-(3,4,5-trimethoxy-p...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against rat heart Phosphodiesterase 1(PDE1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50100680(2-(4-aminophenyl)-1-oxo-7-(2-pyridylmethoxy)-4-(3,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against rat heart Phosphodiesterase 1(PDE1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50100672(2-(4-Amino-phenyl)-6,7-diethoxy-1-oxo-4-(3,4,5-tri...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against rat heart Phosphodiesterase 1(PDE1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50100677(6,7-Dimethoxy-2-(4-methoxy-phenyl)-1-oxo-4-(3,4,5-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against rat heart Phosphodiesterase 1(PDE1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50100652(6,7-Dimethoxy-1-oxo-2-piperidin-1-yl-4-(3,4,5-trim...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against rat heart Phosphodiesterase 1(PDE1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50100683(2-(4-aminophenyl)-1-oxo-7-(2-pyridylmethoxy)-4-(3,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against rat heart Phosphodiesterase 1(PDE1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50100682(2-Cyclohexyl-6,7-dimethoxy-1-oxo-4-(3,4,5-trimetho...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against rat heart Phosphodiesterase 1(PDE1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50100684(6,7-Dimethoxy-2-(4-methylamino-phenyl)-1-oxo-4-(3,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against rat heart Phosphodiesterase 1(PDE1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50100665(2-(4-Chloro-phenyl)-6,7-dimethoxy-1-oxo-4-(3,4,5-t...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against rat heart Phosphodiesterase 1(PDE1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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