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Report error Found 6 of ic50 data for complexid = 50000459
TargetIsocitrate dehydrogenase [NADP] cytoplasmic/ mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM363585(US9850277, Compound 77 | US10689414, Compound 77 |...)
Affinity DataIC50: 100nMAssay Description:Inhibition of IDH1/2 in human U87-MG cells assessed as suppression of 2-HG production incubated for 48 hrs by LC-MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic/ mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM363545(US9850277, Compound 37 | US9850277, Compound 64 | ...)
Affinity DataIC50: 100nMAssay Description:Inhibition of IDH1/2 in human U87-MG cells assessed as suppression of 2-HG production incubated for 48 hrs by LC-MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic/ mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM363580(US9850277, Compound 72 | US10689414, Compound 72 |...)
Affinity DataIC50: 100nMAssay Description:Inhibition of IDH1/2 in human U87-MG cells assessed as suppression of 2-HG production incubated for 48 hrs by LC-MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic/ mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50503259(CHEMBL4591331)
Affinity DataIC50: 100nMAssay Description:Inhibition of IDH1/2 in human U87-MG cells assessed as suppression of 2-HG production incubated for 48 hrs by LC-MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic/ mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM363576(US9850277, Compound 68 | US10689414, Compound 68 |...)
Affinity DataIC50: 100nMAssay Description:Inhibition of IDH1/2 in human U87-MG cells assessed as suppression of 2-HG production incubated for 48 hrs by LC-MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic/ mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50400272(CHEMBL2180727)
Affinity DataIC50: 250nMAssay Description:Inhibition of IDH1/2 in human U87-MG cells assessed as suppression of 2-HG production incubated for 48 hrs by LC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed