Compile Data Set for Download or QSAR
Report error Found 31 of ic50 data for complexid = 50000371
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50323320(3-(3,4-dimethoxyphenyl)-3-(3-(1,2,3,4-tetrahydrois...)
Affinity DataIC50: 0.700nMAssay Description:Displacement of FITC-Fg from integrin alpha2beta3 receptor expressed in human activated plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50323319(3-(4-methoxyphenyl)-3-(3-(1,2,3,4-tetrahydroisoqui...)
Affinity DataIC50: 0.800nMAssay Description:Displacement of FITC-Fg from integrin alpha2beta3 receptor expressed in human activated plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50323318(3-phenyl-3-(3-(1,2,3,4-tetrahydroisoquinolin-7-ylc...)
Affinity DataIC50: 1nMAssay Description:Displacement of FITC-Fg from integrin alpha2beta3 receptor expressed in human activated plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50370766(CHEMBL385939)
Affinity DataIC50: 3.70nMAssay Description:Displacement of FITC-Fg from integrin alpha2beta3 receptor expressed in human activated plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50370765(CHEMBL219051)
Affinity DataIC50: 5nMAssay Description:Displacement of FITC-Fg from integrin alpha2beta3 receptor expressed in human activated plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50354350(CHEMBL1836344)
Affinity DataIC50: 5.5nMAssay Description:Displacement of FITC-labeled fibrinogen from alpha2beta3 in human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50124560(CHEMBL3623706)
Affinity DataIC50: 6.20nMAssay Description:Antagonist activity against integrin alpha2bbeta3 open form in human platelet rich plasma assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50354355(CHEMBL1836351)
Affinity DataIC50: 6.5nMAssay Description:Displacement of FITC-labeled fibrinogen from alpha2beta3 in human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50354352(CHEMBL1836347)
Affinity DataIC50: 6.5nMAssay Description:Displacement of FITC-labeled fibrinogen from alpha2beta3 in human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50354351(CHEMBL1836345)
Affinity DataIC50: 6.80nMAssay Description:Displacement of FITC-labeled fibrinogen from alpha2beta3 in human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50370769(CHEMBL218200)
Affinity DataIC50: 8nMAssay Description:Displacement of FITC-Fg from integrin alpha2beta3 receptor expressed in human activated plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50370768(CHEMBL219603)
Affinity DataIC50: 9nMAssay Description:Displacement of FITC-Fg from integrin alpha2beta3 receptor expressed in human activated plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50124522(CHEMBL3623709)
Affinity DataIC50: 11nMAssay Description:Antagonist activity against integrin alpha2bbeta3 closed form in human platelet rich plasma assessed as inhibition of ADP-induced platelet aggregatio...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50354356(CHEMBL1836355)
Affinity DataIC50: 22nMAssay Description:Displacement of FITC-labeled fibrinogen from alpha2beta3 in human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50124559(CHEMBL3623707)
Affinity DataIC50: 25nMAssay Description:Antagonist activity against integrin alpha2bbeta3 open form in human platelet rich plasma assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50078448(3-{[3-Oxo-2-(2-piperidin-4-yl-ethyl)-2,3-dihydro-1...)
Affinity DataIC50: 25nMAssay Description:Antagonist activity at integrin alpha2beta3-mediated aggregation in ADP-stimulated human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50370767(CHEMBL218226)
Affinity DataIC50: 32nMAssay Description:Displacement of FITC-Fg from integrin alpha2beta3 receptor expressed in human activated plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50004058(N-(butylsulfonyl)-O-(4-piperidin-4-ylbutyl)-L-tyro...)
Affinity DataIC50: 32nMAssay Description:Antagonist activity against integrin alpha2bbeta3 open form in human platelet rich plasma assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50004058(N-(butylsulfonyl)-O-(4-piperidin-4-ylbutyl)-L-tyro...)
Affinity DataIC50: 32nMAssay Description:Antagonist activity against integrin alpha2bbeta3 closed form in human platelet rich plasma assessed as inhibition of ADP-induced platelet aggregatio...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50354354(CHEMBL1836350)
Affinity DataIC50: 37nMAssay Description:Displacement of FITC-labeled fibrinogen from alpha2beta3 in human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50124573(CHEMBL1472460)
Affinity DataIC50: 96nMAssay Description:Antagonist activity against integrin alpha2bbeta3 in human platelet rich plasmaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50124510(CHEMBL3623710)
Affinity DataIC50: 100nMAssay Description:Antagonist activity against integrin alpha2bbeta3 closed form in human platelet rich plasma assessed as inhibition of ADP-induced platelet aggregatio...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50124558(CHEMBL3623708)
Affinity DataIC50: 150nMAssay Description:Antagonist activity against integrin alpha2bbeta3 closed form in human platelet rich plasma assessed as inhibition of ADP-induced platelet aggregatio...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50354348(CHEMBL1836342)
Affinity DataIC50: 270nMAssay Description:Displacement of FITC-labeled fibrinogen from alpha2beta3 in human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50124571(CHEMBL3623501)
Affinity DataIC50: 320nMAssay Description:Antagonist activity against integrin alpha2bbeta3 open form in human platelet rich plasma assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50354353(CHEMBL1836348)
Affinity DataIC50: 350nMAssay Description:Displacement of FITC-labeled fibrinogen from alpha2beta3 in human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50124561(CHEMBL3621231)
Affinity DataIC50: 670nMAssay Description:Antagonist activity against integrin alpha2bbeta3 open form in human platelet rich plasma assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50354349(CHEMBL1836343)
Affinity DataIC50: 1.20E+3nMAssay Description:Displacement of FITC-labeled fibrinogen from alpha2beta3 in human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50063698(4-Guanidino-benzoic acid 6-carbamimidoyl-naphthale...)
Affinity DataIC50: 1.25E+4nMAssay Description:Antagonist activity against integrin alpha2bbeta3 in human platelet rich plasmaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50241180(3-[2-(2-Amino-5-guanidino-pentanoylamino)-acetylam...)
Affinity DataIC50: 1.30E+4nMAssay Description:Displacement of FITC-labeled fibrinogen from alpha2beta3 in human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50124572(CHEMBL1234739)
Affinity DataIC50: 1.30E+4nMAssay Description:Antagonist activity against integrin alpha2bbeta3 in human platelet rich plasmaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)