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TargetIntegrin alpha-M/beta-2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50462087(CHEMBL4243248)
Affinity DataIC50: 140nMAssay Description:Inhibition of C3bi-AP binding to CR3 derived from human PMNMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetIntegrin alpha-M/beta-2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM75309(cid_5709759 | SMR000718614 | MLS001032120 | (2Z)-3...)
Affinity DataIC50: 330nMAssay Description:Inhibition of C3bi-AP binding to CR3 derived from human PMNMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-M/beta-2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50462087(CHEMBL4243248)
Affinity DataIC50: 2.50E+3nMAssay Description:Antagonist activity at CR3 in carboxyfluorescein diacetate succiminidyl ester-labeled human PMN assessed as inhibition of TNF/PMA-stimulated adhesion...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetIntegrin alpha-M/beta-2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM75309(cid_5709759 | SMR000718614 | MLS001032120 | (2Z)-3...)
Affinity DataIC50: 2.50E+3nMAssay Description:Antagonist activity at CR3 in carboxyfluorescein diacetate succiminidyl ester-labeled human PMN assessed as inhibition of TNF/PMA-stimulated adhesion...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-M/beta-2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50055896(CHEMBL22599 | CHEMBL141632 | 3-{2-[3-(4-Carbamimid...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Mac-1 integrin (alphaM-beta2)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-M/beta-2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50055896(CHEMBL22599 | CHEMBL141632 | 3-{2-[3-(4-Carbamimid...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Mac-1 interaction with ICAMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed