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TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandPNGBDBM454848(US10730870, Example 11 | US11512083, Example 11)
Affinity DataIC50: 16.3nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandPNGBDBM454972(US10730870, Example 141 | US11512083, Example 141)
Affinity DataIC50: 70.9nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandPNGBDBM454969(US10730870, Example 138 | US10730870, Example 145 ...)
Affinity DataIC50: 100nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandPNGBDBM454909(US10730870, Example 76 | US11512083, Example 76)
Affinity DataIC50: 169nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandPNGBDBM454884(US10730870, Example 47 | US11512083, Example 47)
Affinity DataIC50: 178nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandPNGBDBM454907(US10730870, Example 74 | US11512083, Example 74)
Affinity DataIC50: 264nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandPNGBDBM454853(US10730870, Example 16 | US11512083, Example 16)
Affinity DataIC50: 265nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandPNGBDBM454897(US10730870, Example 60 | US11512083, Example 60)
Affinity DataIC50: 293nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandPNGBDBM454846(US10730870, Example 9 | US11512083, Example 9)
Affinity DataIC50: 309nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandPNGBDBM454854(US10730870, Example 17 | US11512083, Example 17)
Affinity DataIC50: 317nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandPNGBDBM454916(US10730870, Example 83 | US11512083, Example 83)
Affinity DataIC50: 320nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandPNGBDBM454884(US10730870, Example 47 | US11512083, Example 47)
Affinity DataIC50: 339nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandPNGBDBM454910(US10730870, Example 77 | US11512083, Example 77)
Affinity DataIC50: 349nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandPNGBDBM454881(US10730870, Example 44 | US11512083, Example 44)
Affinity DataIC50: 385nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandPNGBDBM454858(US10730870, Example 21 | US11512083, Example 21)
Affinity DataIC50: 392nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandPNGBDBM454932(US10730870, Example 99 | US11512083, Example 99)
Affinity DataIC50: 418nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandPNGBDBM454863(US10730870, Example 26 | US11512083, Example 26)
Affinity DataIC50: 441nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandPNGBDBM454907(US10730870, Example 74 | US11512083, Example 74)
Affinity DataIC50: 450nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandPNGBDBM454881(US10730870, Example 44 | US11512083, Example 44)
Affinity DataIC50: 465nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandPNGBDBM454890(US10730870, Example 53 | US11512083, Example 53)
Affinity DataIC50: 474nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandPNGBDBM454846(US10730870, Example 9 | US11512083, Example 9)
Affinity DataIC50: 498nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandPNGBDBM454872(US10730870, Example 35 | US11512083, Example 35)
Affinity DataIC50: 509nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandPNGBDBM454839(US10730870, Example 2 | US11512083, Example 2)
Affinity DataIC50: 533nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandPNGBDBM454870(US10730870, Example 33 | US11512083, Example 33)
Affinity DataIC50: 539nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandPNGBDBM454848(US10730870, Example 11 | US11512083, Example 11)
Affinity DataIC50: 542nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandPNGBDBM454910(US10730870, Example 77 | US11512083, Example 77)
Affinity DataIC50: 550nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandPNGBDBM454927(US10730870, Example 94 | US11512083, Example 94)
Affinity DataIC50: 566nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandPNGBDBM454867(US10730870, Example 30 | US11512083, Example 30)
Affinity DataIC50: 572nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandPNGBDBM454900(US10730870, Example 65 | US11512083, Example 65)
Affinity DataIC50: 578nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandPNGBDBM454845(US10730870, Example 8 | US11512083, Example 8)
Affinity DataIC50: 619nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandPNGBDBM454916(US10730870, Example 83 | US11512083, Example 83)
Affinity DataIC50: 626nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandPNGBDBM454900(US10730870, Example 65 | US11512083, Example 65)
Affinity DataIC50: 631nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandPNGBDBM454871(US10730870, Example 34 | US11512083, Example 34)
Affinity DataIC50: 660nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandPNGBDBM454901(US10730870, Example 68 | US11512083, Example 68)
Affinity DataIC50: 668nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandPNGBDBM50099062(CHEMBL3344081 | US10730870, Example 3 | US11512083...)
Affinity DataIC50: 696nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandPNGBDBM454843(US10730870, Example 6 | US10730870, Example 110 | ...)
Affinity DataIC50: 697nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandPNGBDBM454876(US10730870, Example 39 | US11512083, Example 39)
Affinity DataIC50: 699nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandPNGBDBM454894(US10730870, Example 57 | US11512083, Example 57)
Affinity DataIC50: 717nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandPNGBDBM454839(US10730870, Example 2 | US11512083, Example 2)
Affinity DataIC50: 732nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandPNGBDBM454875(US10730870, Example 38 | US11512083, Example 38)
Affinity DataIC50: 758nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandPNGBDBM454842(US10730870, Example 5 | US11512083, Example 5)
Affinity DataIC50: 799nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandPNGBDBM454911(US10730870, Example 78 | US11512083, Example 78)
Affinity DataIC50: 810nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandPNGBDBM454891(US10730870, Example 54 | US11512083, Example 54)
Affinity DataIC50: 834nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandPNGBDBM454855(US10730870, Example 18 | US11512083, Example 18)
Affinity DataIC50: 855nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandPNGBDBM454944(US10730870, Example 111 | US11512083, Example 111)
Affinity DataIC50: 859nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandPNGBDBM454867(US10730870, Example 30 | US11512083, Example 30)
Affinity DataIC50: 859nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandPNGBDBM454905(US10730870, Example 72 | US11512083, Example 72)
Affinity DataIC50: 860nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandPNGBDBM454893(US10730870, Example 56 | US11512083, Example 56)
Affinity DataIC50: 878nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandPNGBDBM454866(US10730870, Example 29 | US11512083, Example 29)
Affinity DataIC50: 905nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandPNGBDBM454880(US10730870, Example 43 | US11512083, Example 43)
Affinity DataIC50: 906nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

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