Compile Data Set for Download or QSAR
Report error Found 32 of ic50 data for complexid = 276
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto

LigandPNGBDBM27614(3-(6-bromo-2-fluoro-3-{1H-pyrazolo[3,4-c]pyridazin...)
Affinity DataIC50: 3nM EC50:  4nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto

LigandPNGBDBM27613(3-(6-bromo-2-fluoro-3-{1H-pyrazolo[3,4-c]pyridin-3...)
Affinity DataIC50: 9nM EC50:  18nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto

LigandPNGBDBM27611(3-[6-bromo-2-fluoro-3-({6-methyl-7-oxo-1H,6H,7H-py...)
Affinity DataIC50: 12nM EC50:  97nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto

LigandPNGBDBM27615(3-(6-bromo-2-fluoro-3-{1H-pyrazolo[3,4-b]pyrazin-3...)
Affinity DataIC50: 14nM EC50: >100nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto

LigandPNGBDBM27609(3-{[4-bromo-3-(3-chloro-5-cyanophenoxy)-2-fluoroph...)
Affinity DataIC50: 15nM EC50:  53nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto

LigandPNGBDBM27583(2-{4-[3-chloro-4-(2-{[1-(2-chloro-4-methylphenyl)-...)
Affinity DataIC50: 22nMAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto

LigandPNGBDBM27610(3-{3-[(7-amino-1H-indazol-3-yl)methyl]-6-bromo-2-f...)
Affinity DataIC50: 22nM EC50:  84nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto

LigandPNGBDBM27602(2-{4-[4-(2-{[4-(4-tert-butyl-2-chlorophenyl)-5-met...)
Affinity DataIC50: 22nMAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto

LigandPNGBDBM27604(2-{[4-(4-tert-butyl-2-chlorophenyl)-5-methyl-1H-py...)
Affinity DataIC50: 24nM EC50:  177nMAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto

LigandPNGBDBM27590(2-{4-[4-(2-{[1-(4-tert-butyl-2-chlorophenyl)-1H-1,...)
Affinity DataIC50: 28nMAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto

LigandPNGBDBM27607(4-[3-chloro-4-(2-{[1-(2-chloro-4-cyclopropylphenyl...)
Affinity DataIC50: 28nMAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto

LigandPNGBDBM27605(4-[4-(2-{[4-(4-tert-butyl-2-chlorophenyl)-5-methyl...)
Affinity DataIC50: 38nM EC50:  73nMAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto

LigandPNGBDBM27584(2-{4-[3-chloro-4-(2-{[1-(2-chloro-4-methylphenyl)-...)
Affinity DataIC50: 48nMAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto

LigandPNGBDBM27599(2-{4-[3-chloro-4-(2-{[4-(2-chloro-4-methylphenyl)-...)
Affinity DataIC50: 107nMAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto

LigandPNGBDBM27603(2-{4-[4-(2-{[4-(4-tert-butyl-2-chlorophenyl)-1H-py...)
Affinity DataIC50: 122nM EC50:  444nMAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto

LigandPNGBDBM27595(2-{4-[3-chloro-4-(2-{[5-(2-chloro-4-methylphenyl)-...)
Affinity DataIC50: 178nMAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto

LigandPNGBDBM27592(2-{4-[3-chloro-4-(2-{[1-(2-chloro-4-methylphenyl)-...)
Affinity DataIC50: 420nMAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto

LigandPNGBDBM27597(2-{4-[3-chloro-4-(2-{[1-(2-chloro-4-methylphenyl)-...)
Affinity DataIC50: 549nMAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto

LigandPNGBDBM27587(2-{4-[3-chloro-4-(2-{[2-(2-chloro-4-methylphenyl)p...)
Affinity DataIC50: 592nMAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto

LigandPNGBDBM27591(2-{4-[3-chloro-4-(2-{[1-(2-chloro-4-methylphenyl)-...)
Affinity DataIC50: 730nMAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto

LigandPNGBDBM27606(2-{[1-(naphthalen-1-yl)-1H-1,2,3,4-tetrazol-5-yl]s...)
Affinity DataIC50: 766nMAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto

LigandPNGBDBM27594(2-{4-[3-chloro-4-(2-{[1-(2-chloro-4-methylphenyl)-...)
Affinity DataIC50: 770nMAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto

LigandPNGBDBM27585(2-(4-{3-chloro-4-[(4Z)-5-(2-chloro-4-methylphenyl)...)
Affinity DataIC50: 785nMAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto

LigandPNGBDBM27600(2-{4-[3-chloro-4-(2-{[4-(2-chloro-4-methylphenyl)-...)
Affinity DataIC50: 796nMAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto

LigandPNGBDBM27589(2-{[1-(2-chloro-4-methylphenyl)-1H-1,2,3,4-tetrazo...)
Affinity DataIC50: 809nMAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto

LigandPNGBDBM27588(2-[4-(3-chloro-4-{2-[2-(2-chloro-4-methylphenyl)ph...)
Affinity DataIC50: 1.39E+3nMAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto

LigandPNGBDBM27601(2-{4-[3-chloro-4-(2-{[4-(2-chloro-4-methylphenyl)-...)
Affinity DataIC50: 1.46E+3nMAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto

LigandPNGBDBM27596(2-{4-[3-chloro-4-(2-{[2-(2-chloro-4-methylphenyl)-...)
Affinity DataIC50: 2.68E+3nMAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto

LigandPNGBDBM27586(2-(4-{3-chloro-4-[(4E)-5-(2-chloro-4-methylphenyl)...)
Affinity DataIC50: 3.27E+3nMAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto

LigandPNGBDBM27608(2-{4-[3-chloro-4-(2-{[3-(2-chloro-4-methylphenyl)-...)
Affinity DataIC50: 6.48E+3nMAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto

LigandPNGBDBM27593(2-{4-[3-chloro-4-(2-{[1-(2-chloro-4-methylphenyl)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto

LigandPNGBDBM27598(2-{[1-(2-chloro-4-methylphenyl)-4-methyl-1H-imidaz...)
Affinity DataIC50: 1.00E+4nMAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed