UniProt Accession IDs for Pathway crenolanib-resistant FLT3 mutants

The UniProt or TrEMBL identifiers listed in this pages are extracted from UniProt2Reactome_All_Levels.txt, whose links of the affinity data in BindingDB are also listed.

  1. Primary ID
    UniProt Recommended Name
    Secondary IDs
    BindingDB Name
    Affinity Link(s)
    Articles
    Downloads
  2. P36888
    Receptor-type tyrosine-protein kinase FLT3
    A0AVG9 B7ZLT7 B7ZLT8 F5H0A0 Q13414
    Receptor-type tyrosine-protein kinase FLT3 [R834Q]
    Kd: 23
    3
    2D 3D TSV
  3. P36888
    Receptor-type tyrosine-protein kinase FLT3
    A0AVG9 B7ZLT7 B7ZLT8 F5H0A0 Q13414
    Receptor-type tyrosine-protein kinase FLT3 [K663Q]
    Kd: 18
    2
    2D 3D TSV
  4. P36888
    Receptor-type tyrosine-protein kinase FLT3
    A0AVG9 B7ZLT7 B7ZLT8 F5H0A0 Q13414
    Receptor-type tyrosine-protein kinase FLT3 [564-993]
    IC50: 37
    1
    2D 3D TSV
  5. P36888
    Receptor-type tyrosine-protein kinase FLT3
    A0AVG9 B7ZLT7 B7ZLT8 F5H0A0 Q13414
    Receptor-type tyrosine-protein kinase FLT3 [563-993,D835Y]
    IC50: 1
    1
    2D 3D TSV
  6. P36888
    Receptor-type tyrosine-protein kinase FLT3
    A0AVG9 B7ZLT7 B7ZLT8 F5H0A0 Q13414
    Receptor-type tyrosine-protein kinase FLT3 [N841I]
    Kd: 45
    4
    2D 3D TSV
  7. P36888
    Receptor-type tyrosine-protein kinase FLT3
    A0AVG9 B7ZLT7 B7ZLT8 F5H0A0 Q13414
    Receptor-type tyrosine-protein kinase FLT3 [572-603]
    Kd: 17
    1
    2D 3D TSV
  8. P36888
    Receptor-type tyrosine-protein kinase FLT3
    A0AVG9 B7ZLT7 B7ZLT8 F5H0A0 Q13414
    Receptor-type tyrosine-protein kinase FLT3 [564-710,762-958]
    Kd: 5
    1
    2D 3D TSV
  9. P36888
    Receptor-type tyrosine-protein kinase FLT3
    A0AVG9 B7ZLT7 B7ZLT8 F5H0A0 Q13414
    Receptor-type tyrosine-protein kinase FLT3
    Ki: 162 IC50: 5016 Kd: 1246 EC50: 32
    514
    2D 3D TSV
  10. P36888
    Receptor-type tyrosine-protein kinase FLT3
    A0AVG9 B7ZLT7 B7ZLT8 F5H0A0 Q13414
    Receptor-type tyrosine-protein kinase FLT3 [D835V]
    Kd: 22
    2
    2D 3D TSV
  11. P36888
    Receptor-type tyrosine-protein kinase FLT3
    A0AVG9 B7ZLT7 B7ZLT8 F5H0A0 Q13414
    Receptor-type tyrosine-protein kinase FLT3 (D835Y)
    IC50: 54 Kd: 46
    7
    2D 3D TSV
  12. P36888
    Receptor-type tyrosine-protein kinase FLT3
    A0AVG9 B7ZLT7 B7ZLT8 F5H0A0 Q13414
    Receptor-type tyrosine-protein kinase FLT3 [D835H]
    Kd: 48
    5
    2D 3D TSV
  13. P36888
    Receptor-type tyrosine-protein kinase FLT3
    A0AVG9 B7ZLT7 B7ZLT8 F5H0A0 Q13414
    Receptor-type tyrosine-protein kinase FLT3 [564-960]
    IC50: 27
    1
    2D 3D TSV
  14. P36888
    Receptor-type tyrosine-protein kinase FLT3
    A0AVG9 B7ZLT7 B7ZLT8 F5H0A0 Q13414
    Dimer of Receptor-type tyrosine-protein kinase FLT3 [F691L]
    Kd: 17
    1
    2D 3D TSV
  15. P36888
    Receptor-type tyrosine-protein kinase FLT3
    A0AVG9 B7ZLT7 B7ZLT8 F5H0A0 Q13414
    Dimer of Receptor-type tyrosine-protein kinase FLT3 [D835V]
    Kd: 17
    1
    2D 3D TSV
  16. P36888
    Receptor-type tyrosine-protein kinase FLT3
    A0AVG9 B7ZLT7 B7ZLT8 F5H0A0 Q13414
    Dimer of Receptor-type tyrosine-protein kinase FLT3 [D835V]
    Kd: 5
    1
    2D 3D TSV
  17. P36888
    Receptor-type tyrosine-protein kinase FLT3
    A0AVG9 B7ZLT7 B7ZLT8 F5H0A0 Q13414
    Dimer of Receptor-type tyrosine-protein kinase FLT3 [F691L]
    Kd: 5
    1
    2D 3D TSV
  18. P36888
    Receptor-type tyrosine-protein kinase FLT3
    A0AVG9 B7ZLT7 B7ZLT8 F5H0A0 Q13414
    Dimer of Receptor-type tyrosine-protein kinase FLT3
    IC50: 152 Kd: 22
    8
    2D 3D TSV
  19. P36888
    Receptor-type tyrosine-protein kinase FLT3
    A0AVG9 B7ZLT7 B7ZLT8 F5H0A0 Q13414
    ...
    Ki: 162 IC50: 5287 Kd: 1536 EC50: 32
    525
    2D 3D TSV