Report error Found 1783 Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D'
Affinity DataKd: 3.90nMAssay Description:Binding affinity for sarcoplasmic reticulum phosphodiesterase 4 of canine ventricleMore data for this Ligand-Target Pair
Affinity DataKd: 4.10nMAssay Description:Binding affinity for Phosphodiesterase 4 of canine myocardial vesiclesMore data for this Ligand-Target Pair
Affinity DataEC50: 7.50E+3nMAssay Description:Increased cAMP accumulation in isoprenaline-induced guinea pig eosinophilsMore data for this Ligand-Target Pair
Affinity DataEC50: 3.50E+3nMAssay Description:Increased cAMP accumulation in isoprenaline-induced guinea pig eosinophilsMore data for this Ligand-Target Pair
Affinity DataEC50: 2.10E+4nMAssay Description:Increased cAMP accumulation in isoprenaline-induced guinea pig eosinophilsMore data for this Ligand-Target Pair
Affinity DataEC50: 1.05E+3nMAssay Description:Increased cAMP accumulation in isoprenaline-induced guinea pig eosinophilsMore data for this Ligand-Target Pair
Affinity DataEC50: 600nMAssay Description:Increased cAMP accumulation in isoprenaline-induced guinea pig eosinophilsMore data for this Ligand-Target Pair
Affinity DataEC50: 1.80E+4nMAssay Description:Increased cAMP accumulation in isoprenaline-induced guinea pig eosinophilsMore data for this Ligand-Target Pair
Affinity DataEC50: 2.10E+3nMAssay Description:Increased cAMP accumulation in isoprenaline-induced guinea pig eosinophilsMore data for this Ligand-Target Pair
Affinity DataEC50: 1.70E+3nMAssay Description:Increased cAMP accumulation in isoprenaline-induced guinea pig eosinophilsMore data for this Ligand-Target Pair
Affinity DataEC50: 700nMAssay Description:Increased cAMP accumulation in isoprenaline-induced guinea pig eosinophilsMore data for this Ligand-Target Pair
Affinity DataEC50: 1.80E+3nMAssay Description:Increased cAMP accumulation in isoprenaline-induced guinea pig eosinophilsMore data for this Ligand-Target Pair
Affinity DataEC50: 3.40E+3nMAssay Description:Increased cAMP accumulation in isoprenaline-induced guinea pig eosinophilsMore data for this Ligand-Target Pair
Affinity DataEC50: 1.80E+3nMAssay Description:Increased cAMP accumulation in isoprenaline-induced guinea pig eosinophilsMore data for this Ligand-Target Pair
Affinity DataEC50: 200nMAssay Description:Increased cAMP accumulation in isoprenaline-induced guinea pig eosinophilsMore data for this Ligand-Target Pair
Affinity DataEC50: 2.00E+3nMAssay Description:Increased cAMP accumulation in isoprenaline-induced guinea pig eosinophilsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.00300nMAssay Description:Inhibition of human PDE4 expressed in Saccharomyces cerevisiae preincubated for 30 mins followed by cAMP substrate additionMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 0.00300nMAssay Description:Inhibition of human PDE4 expressed in Sf9 cells by non-linear regression analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0260nMAssay Description:Inhibition of PDE4 in human U937 cell lysate using cAMP as substrate by LANCE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of PDE4 (unknown origin) expressed in Saccharomyces cerevisiae using [3H] cAMP as substrate incubated for 1 hr by scintillation proximity ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of PDE4 activity in human PBMC assessed as inhibition of LPS-induced TNFalpha release after 18 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of PDE4 (unknown origin) expressed in Saccharomyces cerevisiae using [3H] cAMP as substrate incubated for 1 hr by scintillation proximity ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0510nMAssay Description:Inhibition of phosphodiesterase 4 (PDE4) prepared from human U937 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of PDE4 activity in human PBMC assessed as inhibition of LPS-induced TNFalpha release after 18 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of PDE4 activity in human PBMC assessed as inhibition of LPS-induced TNFalpha release after 18 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0720nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of phosphodiesterase 4 (PDE4) prepared from human U937 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMAssay Description:Inhibition of PDE4 activity in human PBMC assessed as inhibition of LPS-induced TNFalpha release after 18 hrs by ELISAMore data for this Ligand-Target Pair
