Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with Target = 'cAMP-dependent protein kinase catalytic subunit alpha [V123M]'
TargetcAMP-dependent protein kinase catalytic subunit alpha [V123M](Bovine)
German Cancer Research Center

LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 45nMpH: 6.8 T: 2°CAssay Description:The enzyme activity was assayed by using an ATP regenerative NADH consuming system. The reaction was started with adding ATP to the mixture containin...More data for this Ligand-Target Pair
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PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha [V123M](Bovine)
German Cancer Research Center

LigandPNGBDBM14030(hexyl (15R,16S,18S)-16-hydroxy-15-methyl-3-oxo-28-...)
Affinity DataIC50: 222nMpH: 6.8 T: 2°CAssay Description:The enzyme activity was assayed by using an ATP regenerative NADH consuming system. The reaction was started with adding ATP to the mixture containin...More data for this Ligand-Target Pair
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PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha [V123M](Bovine)
German Cancer Research Center

LigandPNGBDBM14028(H-1152 | 4-methyl-5-{[(2S)-2-methyl-1,4-diazepane-...)
Affinity DataIC50: 1.52E+3nMpH: 6.8 T: 2°CAssay Description:The enzyme activity was assayed by using an ATP regenerative NADH consuming system. The reaction was started with adding ATP to the mixture containin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha [V123M](Bovine)
German Cancer Research Center

LigandPNGBDBM14027(AT877 | CHEMBL38380 | 5-(1,4-diazepan-1-ylsulfonyl...)
Affinity DataIC50: 7.61E+3nMpH: 6.8 T: 2°CAssay Description:The enzyme activity was assayed by using an ATP regenerative NADH consuming system. The reaction was started with adding ATP to the mixture containin...More data for this Ligand-Target Pair
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PubMedPDB3D3D Structure (crystal)
TargetcAMP-dependent protein kinase catalytic subunit alpha [V123M](Bovine)
German Cancer Research Center

LigandPNGBDBM14029(4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...)
Affinity DataIC50: 6.00E+4nMpH: 6.8 T: 2°CAssay Description:The enzyme activity was assayed by using an ATP regenerative NADH consuming system. The reaction was started with adding ATP to the mixture containin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed