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Report error Found 2447 Enz. Inhib. hit(s) with Target = 'Xanthine dehydrogenase/oxidase'
TargetXanthine dehydrogenase/oxidase(Bovine)
University of Nis

Curated by ChEMBL
LigandPNGBDBM50140241(CHEBI:40279 | Allopurinol | Aloral | Aluline 100 |...)
Affinity DataKd:  0.540nMAssay Description:Binding affinity to bovine milk xanthine oxidase assessed as reduction in conversion of 4-HPP to 4,6-diHPP by measuring cytochrome c reduction by spe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of Nis

Curated by ChEMBL
LigandPNGBDBM50462190(CHEMBL4240097)
Affinity DataEC50:  1.02E+4nMAssay Description:Inhibition of bovine xanthine oxidase assessed as reduction in uric acid formation using xanthine as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of Nis

Curated by ChEMBL
LigandPNGBDBM50462191(CHEMBL4249720)
Affinity DataEC50:  8.13E+3nMAssay Description:Inhibition of bovine xanthine oxidase assessed as reduction in uric acid formation using xanthine as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of Nis

Curated by ChEMBL
LigandPNGBDBM50254554(4-(3-(4-isobutoxy-3-nitrophenyl)-1H-1,2,4-triazol-...)
Affinity DataEC50:  10nMAssay Description:Inhibition of bovine xanthine oxidase assessed as reduction in uric acid formation using xanthine as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of Nis

Curated by ChEMBL
LigandPNGBDBM50462192(CHEMBL4248086)
Affinity DataEC50:  2.09E+4nMAssay Description:Inhibition of bovine xanthine oxidase assessed as reduction in uric acid formation using xanthine as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of Nis

Curated by ChEMBL
LigandPNGBDBM50254505(2-(2-(2-(2-chloroethoxy)ethoxy)ethoxy)-5-(5-(2-met...)
Affinity DataEC50:  21nMAssay Description:Inhibition of bovine xanthine oxidase assessed as reduction in uric acid formation using xanthine as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of Nis

Curated by ChEMBL
LigandPNGBDBM50254558(2-(2-cyano-4-(5-(2-methylpyridin-4-yl)-2H-1,2,4-tr...)
Affinity DataEC50:  110nMAssay Description:Inhibition of bovine xanthine oxidase assessed as reduction in uric acid formation using xanthine as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of Nis

Curated by ChEMBL
LigandPNGBDBM50462194(CHEMBL4243871)
Affinity DataEC50:  6.76E+3nMAssay Description:Inhibition of bovine xanthine oxidase assessed as reduction in uric acid formation using xanthine as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of Nis

Curated by ChEMBL
LigandPNGBDBM50254497(3-(5-(4-isobutoxy-3-nitrophenyl)-1H-1,2,4-triazol-...)
Affinity DataEC50:  5.89E+3nMAssay Description:Inhibition of bovine xanthine oxidase assessed as reduction in uric acid formation using xanthine as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of Nis

Curated by ChEMBL
LigandPNGBDBM50462195(CHEMBL4240082)
Affinity DataEC50:  646nMAssay Description:Inhibition of bovine xanthine oxidase assessed as reduction in uric acid formation using xanthine as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of Nis

Curated by ChEMBL
LigandPNGBDBM50462196(CHEMBL4238313)
Affinity DataEC50:  9.55E+3nMAssay Description:Inhibition of bovine xanthine oxidase assessed as reduction in uric acid formation using xanthine as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of Nis

Curated by ChEMBL
LigandPNGBDBM50462193(CHEMBL4240552)
Affinity DataEC50:  1.55E+4nMAssay Description:Inhibition of bovine xanthine oxidase assessed as reduction in uric acid formation using xanthine as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of Nis

Curated by ChEMBL
LigandPNGBDBM50254506(2-((2,2-dimethyl-1,3-dioxolan-4-yl)methoxy)-5-(5-(...)
Affinity DataEC50:  60nMAssay Description:Inhibition of bovine xanthine oxidase assessed as reduction in uric acid formation using xanthine as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of Nis

Curated by ChEMBL
LigandPNGBDBM50254503(2-(2-(2-methoxyethoxy)ethoxy)-5-(5-(2-methylpyridi...)
Affinity DataEC50:  31nMAssay Description:Inhibition of bovine xanthine oxidase assessed as reduction in uric acid formation using xanthine as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of Nis

Curated by ChEMBL
LigandPNGBDBM50254561(2-(methoxymethoxy)-5-(5-(2-methylpyridin-4-yl)-2H-...)
Affinity DataEC50:  24nMAssay Description:Inhibition of bovine xanthine oxidase assessed as reduction in uric acid formation using xanthine as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of Nis

Curated by ChEMBL
LigandPNGBDBM50254560(2-(2-methoxyethoxy)-5-(5-(2-methylpyridin-4-yl)-2H...)
Affinity DataEC50:  65nMAssay Description:Inhibition of bovine xanthine oxidase assessed as reduction in uric acid formation using xanthine as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of Nis

Curated by ChEMBL
LigandPNGBDBM50254502(2-hydroxy-5-(5-(2-methylpyridin-4-yl)-2H-1,2,4-tri...)
Affinity DataEC50:  43nMAssay Description:Inhibition of bovine xanthine oxidase assessed as reduction in uric acid formation using xanthine as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of Nis

Curated by ChEMBL
LigandPNGBDBM50254500(ethyl 2-isobutoxy-5-(5-(2-methylpyridin-4-yl)-2H-1...)
Affinity DataEC50:  20nMAssay Description:Inhibition of bovine xanthine oxidase assessed as reduction in uric acid formation using xanthine as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of Nis

Curated by ChEMBL
LigandPNGBDBM50254499(2-isobutoxy-5-(5-(2-methylpyridin-4-yl)-1H-1,2,4-t...)
Affinity DataEC50:  17nMAssay Description:Inhibition of bovine xanthine oxidase assessed as reduction in uric acid formation using xanthine as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of Nis

Curated by ChEMBL
LigandPNGBDBM50462197(CHEMBL4237723)
Affinity DataEC50:  6.76E+3nMAssay Description:Inhibition of bovine xanthine oxidase assessed as reduction in uric acid formation using xanthine as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of Nis

Curated by ChEMBL
LigandPNGBDBM50462198(CHEMBL4243524)
Affinity DataEC50:  2.51E+4nMAssay Description:Inhibition of bovine xanthine oxidase assessed as reduction in uric acid formation using xanthine as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of Nis

Curated by ChEMBL
LigandPNGBDBM50462199(CHEMBL4251498)
Affinity DataEC50:  1.62E+4nMAssay Description:Inhibition of bovine xanthine oxidase assessed as reduction in uric acid formation using xanthine as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of Nis

Curated by ChEMBL
LigandPNGBDBM50462201(CHEMBL4251121)
Affinity DataEC50:  4.79E+3nMAssay Description:Inhibition of bovine xanthine oxidase assessed as reduction in uric acid formation using xanthine as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of Nis

Curated by ChEMBL
LigandPNGBDBM50254504(2-(2-(2-butoxyethoxy)ethoxy)-5-(5-(2-methylpyridin...)
Affinity DataEC50:  26nMAssay Description:Inhibition of bovine xanthine oxidase assessed as reduction in uric acid formation using xanthine as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of Nis

Curated by ChEMBL
LigandPNGBDBM50254559(2-(2-hydroxyethoxy)-5-(5-(2-methylpyridin-4-yl)-2H...)
Affinity DataEC50:  40nMAssay Description:Inhibition of bovine xanthine oxidase assessed as reduction in uric acid formation using xanthine as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of Nis

Curated by ChEMBL
LigandPNGBDBM50462202(CHEMBL4243408)
Affinity DataEC50:  2.34E+4nMAssay Description:Inhibition of bovine xanthine oxidase assessed as reduction in uric acid formation using xanthine as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of Nis

Curated by ChEMBL
LigandPNGBDBM50462203(CHEMBL4239301)
Affinity DataEC50:  1.82E+4nMAssay Description:Inhibition of bovine xanthine oxidase assessed as reduction in uric acid formation using xanthine as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of Nis

Curated by ChEMBL
LigandPNGBDBM50462204(CHEMBL4239183)
Affinity DataEC50:  4.47E+4nMAssay Description:Inhibition of bovine xanthine oxidase assessed as reduction in uric acid formation using xanthine as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of Nis

Curated by ChEMBL
LigandPNGBDBM50462200(CHEMBL4248090)
Affinity DataEC50:  4.37E+3nMAssay Description:Inhibition of bovine xanthine oxidase assessed as reduction in uric acid formation using xanthine as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of Nis

Curated by ChEMBL
LigandPNGBDBM50254562(2-((2-methoxyethoxy)methoxy)-5-(5-(2-methylpyridin...)
Affinity DataEC50:  24nMAssay Description:Inhibition of bovine xanthine oxidase assessed as reduction in uric acid formation using xanthine as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of Nis

Curated by ChEMBL
LigandPNGBDBM50254555(2-chloro-4-(5-(4-isobutoxy-3-nitrophenyl)-1H-1,2,4...)
Affinity DataEC50:  10nMAssay Description:Inhibition of bovine xanthine oxidase assessed as reduction in uric acid formation using xanthine as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM499668(US11020397, Compound Formula-(IIz))
Affinity DataIC50: 0.0150nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM499645(US11020397, Compound Formula-(IIi))
Affinity DataIC50: 0.0200nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM499646(US11020397, Compound Formula-(IIjj))
Affinity DataIC50: 0.0200nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM499652(US11020397, Compound Formula-(IIl))
Affinity DataIC50: 0.0200nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM499675(US11020397, Compound Formula-(IIee))
Affinity DataIC50: 0.0290nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM499657(US11020397, Compound Formula-(IIq))
Affinity DataIC50: 0.0400nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM499681(US11020397, Compound Formula-(II5))
Affinity DataIC50: 0.0400nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM50140241(CHEBI:40279 | Allopurinol | Aloral | Aluline 100 |...)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of XO (unknown origin) using xanthine as substrateMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM499679(US11020397, Compound Formula-(II3))
Affinity DataIC50: 0.0600nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM499680(US11020397, Compound Formula-(II4))
Affinity DataIC50: 0.0600nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM499684(US11020397, Compound Formula-(II8))
Affinity DataIC50: 0.0600nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM499673(US11020397, Compound Formula-(IIdd))
Affinity DataIC50: 0.0640nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM499683(US11020397, Compound Formula-(II7))
Affinity DataIC50: 0.0700nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM50625674(CHEMBL5403463)
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of XO (unknown origin) using xanthine as substrateMore data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM50625673(CHEMBL5421553)
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of XO (unknown origin) using xanthine as substrateMore data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM499664(US11020397, Compound Formula-(IIv))
Affinity DataIC50: 0.100nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM499670(US11020397, Compound Formula-(IIaa))
Affinity DataIC50: 0.103nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM499659(US11020397, Compound Formula-(IIs))
Affinity DataIC50: 0.120nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM499662(US11020397, Compound Formula-(IIt))
Affinity DataIC50: 0.180nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In DepthDetails
US Patent

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