Compile Data Set for Download or QSAR
Report error Found 89 Enz. Inhib. hit(s) with Target = 'Wee1-like protein kinase 2'
TargetWee1-like protein kinase 2(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM25919(N-(2-aminoethyl)-3,12-dimethyl-2,5,8-triazatricycl...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for WEE2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetWee1-like protein kinase 2(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM25045(CHEMBL538346 | mTOR Inhibitor, PI103 | PI-103 | 3-...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for WEE2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetWee1-like protein kinase 2(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM4851(cid_151194 | PTK787 | CHEMBL101253 | N-(4-chloroph...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for WEE2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetWee1-like protein kinase 2(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataKd:  94nMAssay Description:Binding constant for WEE2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetWee1-like protein kinase 2(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50355495(CHEMBL1908391)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for WEE2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetWee1-like protein kinase 2(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50355496(CHEMBL1908397)
Affinity DataKd:  4.70E+3nMAssay Description:Binding constant for WEE2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetWee1-like protein kinase 2(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM12621(2,4-Diamino-5-ketopyrimidine 39 | 5-[(2,3-difluoro...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for WEE2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetWee1-like protein kinase 2(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM25013(4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for WEE2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetWee1-like protein kinase 2(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50355499(CHEMBL1908395 | CHEMBL1908842)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for WEE2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetWee1-like protein kinase 2(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM60665(US9145414, R406 | US9212178, R406 | BDBM50249542)
Affinity DataKd:  9.40E+3nMAssay Description:Binding constant for WEE2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetWee1-like protein kinase 2(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50355497(AZD-6244 | CHEMBL1614701)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for WEE2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetWee1-like protein kinase 2(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM13535(N-(4-isopropoxyphenyl)-4-[6-methoxy-7-(3-piperidin...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for WEE2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetWee1-like protein kinase 2(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50355494(CHEMBL1908396)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for WEE2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetWee1-like protein kinase 2(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM36409(CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for WEE2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetWee1-like protein kinase 2(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM15138(Biochemistry 469551 Compound 11 | 5-indazolyl pyri...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for WEE2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetWee1-like protein kinase 2(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM13216(N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyeth...)
Affinity DataKd:  200nMAssay Description:Binding constant for WEE2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetWee1-like protein kinase 2(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50132260(CHEMBL105442 | US8575391, 341 | CI-1040 | 2-(2-chl...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for WEE2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetWee1-like protein kinase 2(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM5931(cid_3025986 | CHEMBL296468 | N-(5-{[(5-tert-butyl-...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for WEE2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetWee1-like protein kinase 2(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM13336(4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for WEE2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetWee1-like protein kinase 2(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM25617(N-[3-({5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl}carb...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for WEE2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetWee1-like protein kinase 2(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50355501(RUXOLITINIB PHOSPHATE | INCB-018424 | RUXOLITINIB ...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for WEE2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetWee1-like protein kinase 2(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM26474(GW-786034 | JMC514632 Compound 13 | 5-({4-[(2,3-di...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for WEE2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetWee1-like protein kinase 2(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50355504(CHEMBL1908393)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for WEE2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetWee1-like protein kinase 2(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50240827(CHEMBL4075828)
Affinity DataKd:  128nMAssay Description:Binding affinity to recombinant human N-terminal His6-tagged Wee2 kinase domain (202 to 492 residues) expressed in Escherichia coli BL21 (DE3) by iso...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetWee1-like protein kinase 2(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM31545(Milciclib | pyrazolo[4,3-h]quinazoline-3-carboxami...)
Affinity DataKd:  27nMAssay Description:Binding affinity to recombinant human N-terminal His6-tagged Wee2 kinase domain (202 to 492 residues) expressed in Escherichia coli BL21 (DE3) by iso...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetWee1-like protein kinase 2(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50240826(AZD-1775 | MK-1775 | US11124518, Example AZD1775 |...)
Affinity DataKd:  3.90nMAssay Description:Binding affinity to recombinant human full-length N-terminal His8-tagged Wee2 (1 to 567 residues) expressed in human Expi293F cells assessed as desso...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetWee1-like protein kinase 2(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM13216(N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyeth...)
Affinity DataKd:  481nMAssay Description:Binding affinity to recombinant human N-terminal His6-tagged Wee2 kinase domain (202 to 492 residues) expressed in Escherichia coli BL21 (DE3) by iso...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetWee1-like protein kinase 2(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM31090((E)-N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-etho...)
Affinity DataKd:  498nMAssay Description:Binding affinity to recombinant human N-terminal His6-tagged Wee2 kinase domain (202 to 492 residues) expressed in Escherichia coli BL21 (DE3) by iso...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetWee1-like protein kinase 2(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataKd:  106nMAssay Description:Binding affinity to recombinant human N-terminal His6-tagged Wee2 kinase domain (202 to 492 residues) expressed in Escherichia coli BL21 (DE3) by iso...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetWee1-like protein kinase 2(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50240828(CHEMBL4067978)
Affinity DataKd:  4.70nMAssay Description:Binding affinity to recombinant human N-terminal His6-tagged Wee2 kinase domain (202 to 492 residues) expressed in Escherichia coli BL21 (DE3) by iso...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetWee1-like protein kinase 2(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50240826(AZD-1775 | MK-1775 | US11124518, Example AZD1775 |...)
Affinity DataKd:  27nMAssay Description:Binding affinity to recombinant human N-terminal His6-tagged Wee2 kinase domain (202 to 492 residues) expressed in Escherichia coli BL21 (DE3) by iso...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetWee1-like protein kinase 2(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM3096(6-(2,6-dichlorophenyl)-2-({4-[2-(diethylamino)etho...)
Affinity DataKd:  5nMAssay Description:Binding affinity to recombinant human N-terminal His6-tagged Wee2 kinase domain (202 to 492 residues) expressed in Escherichia coli BL21 (DE3) by iso...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetWee1-like protein kinase 2(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM21079(1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for WEE2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetWee1-like protein kinase 2(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50308060(CEP-701 | 16-hydroxy-16-(hydroxymethyl)-15-methyl-...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to WEE2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetWee1-like protein kinase 2(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM5446(Erlotinib | OSI-774 | N-(3-ethynylphenyl)-6,7-bis(...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for WEE2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetWee1-like protein kinase 2(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM24654(pyrazole diamide, 33 | 4-N-(2,6-dichlorobenzene)-3...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for WEE2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetWee1-like protein kinase 2(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM25028(4-[2-(1H-indazol-4-yl)-6-[(4-methanesulfonylpipera...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for WEE2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetWee1-like protein kinase 2(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM31093(cid_11712649 | 4-[[7-[2,6-bis(fluoranyl)phenyl]-9-...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for WEE2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetWee1-like protein kinase 2(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM24773(N-(3,3-dimethyl-2,3-dihydro-1H-indol-6-yl)-2-[(pyr...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for WEE2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetWee1-like protein kinase 2(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50300690(CHEMBL576982 | N-(5-tert-Butyl-isoxazol-3-yl)-N'-{...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for WEE2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetWee1-like protein kinase 2(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM13534(VX680 | N-[4-[[4-(4-methylpiperazino)-6-[(5-methyl...)
Affinity DataKd:  4.20E+3nMAssay Description:Binding constant for WEE2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetWee1-like protein kinase 2(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM5447(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for WEE2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetWee1-like protein kinase 2(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM4779(cid_156414 | PD0183805 | CHEMBL545315 | CHEMBL3196...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for WEE2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetWee1-like protein kinase 2(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50242737((R,Z)-5-(2,6-dichlorobenzylsulfonyl)-3-((3,5-dimet...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for WEE2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetWee1-like protein kinase 2(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM27817(2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for WEE2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetWee1-like protein kinase 2(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50322823((S)-N-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahy...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for WEE2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetWee1-like protein kinase 2(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for WEE2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetWee1-like protein kinase 2(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM17055((9S)-9-[(dimethylamino)methyl]-6,7,10,11-tetrahydr...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for WEE2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetWee1-like protein kinase 2(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM31085(cid_11409972 | 1-[4-[(4-ethylpiperazin-1-yl)methyl...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for WEE2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetWee1-like protein kinase 2(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for WEE2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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