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Report error Found 469 Enz. Inhib. hit(s) with Target = 'Vesicular acetylcholine transporter'
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50292902((2R,3R)-3-(4-(aminomethyl)-4-phenylpiperidin-1-yl)...)
Affinity DataKd:  3nMAssay Description:Displacement of [3H]vesamicol from human vesicular acetylcholine transporter expressed in rat PC12 cells by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVesicular acetylcholine transporter(Rat)
Kanazawa University

Curated by ChEMBL
LigandPNGBDBM50389432(CHEMBL2064618)
Affinity DataKd:  1.73nMAssay Description:Binding affinity to VAChT in Sprague-Dawley rat cerebral membrane after 1 hr by gamma counting in presence of haloperidolMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVesicular acetylcholine transporter(Rat)
Kanazawa University

Curated by ChEMBL
LigandPNGBDBM50009602(CHEMBL89298 | 2-(4-Phenyl-piperidin-1-yl)-cyclohex...)
Affinity DataKd:  7.40nMAssay Description:Binding affinity to VAChT in Sprague-Dawley rat cerebral membrane after 1 hr by gamma counting in presence of DTGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVesicular acetylcholine transporter(Rat)
Kanazawa University

Curated by ChEMBL
LigandPNGBDBM50389434(CHEMBL2064619)
Affinity DataKd:  17.4nMAssay Description:Binding affinity to VAChT in rat cerebral membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50018100(CHEMBL20721 | (+/-)-trans-2-hydroxy-3-(4-phenylpip...)
Affinity DataIC50: 10nMAssay Description:Inhibition of active transport of [3H]acetylcholine using purified Torpedo californica synaptic vesiclesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50018100(CHEMBL20721 | (+/-)-trans-2-hydroxy-3-(4-phenylpip...)
Affinity DataIC50: 10nMAssay Description:Inhibition of active transport of [3H]acetylcholine using purified Torpedo californica synaptic vesiclesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50183824(1-(2-bromobenzyl)-4-(4-phenylpiperazin-1-yl)piperi...)
Affinity DataIC50: 11nMAssay Description:Displacement of [3H]vesamicol from human VAChT transfected in PC12 cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVesicular acetylcholine transporter(Pacific electric ray)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50368841(CHEMBL1204343)
Affinity DataIC50: 14nMAssay Description:Inhibition of [3H]- vesamicol binding to synaptic vesicles preparation from the electric organ of Torpedo californicaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50018108(trans-(4S)-4-tert-butyl-2-(4-phenylpiperidin-1-yl)...)
Affinity DataIC50: 20nMAssay Description:Inhibition of active transport of [3H]acetylcholine using purified Torpedo californica synaptic vesiclesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50018094((1R,2R)-2-(4-Phenyl-piperidin-1-yl)-cyclohexanol |...)
Affinity DataIC50: 20nMAssay Description:Inhibition of active transport of [3H]acetylcholine using purified Torpedo californica synaptic vesiclesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVesicular acetylcholine transporter(Pacific electric ray)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50368838(CHEMBL1203910)
Affinity DataIC50: 21nMAssay Description:Inhibition of [3H]- vesamicol binding to synaptic vesicles preparation from the electric organ of Torpedo californicaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVesicular acetylcholine transporter(Pacific electric ray)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50368833(CHEMBL1203897)
Affinity DataIC50: 22nMAssay Description:Inhibition of [3H]- vesamicol binding to synaptic vesicles preparation from the electric organ of Torpedo californicaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVesicular acetylcholine transporter(Pacific electric ray)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50368840(CHEMBL1203906)
Affinity DataIC50: 22nMAssay Description:Inhibition of [3H]- vesamicol binding to synaptic vesicles preparation from the electric organ of Torpedo californicaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVesicular acetylcholine transporter(Pacific electric ray)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50368843(CHEMBL1203913)
Affinity DataIC50: 22nMAssay Description:Inhibition of [3H]- vesamicol binding to synaptic vesicles preparation from the electric organ of Torpedo californicaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVesicular acetylcholine transporter(Pacific electric ray)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50368847(CHEMBL1203903)
Affinity DataIC50: 24nMAssay Description:Inhibition of [3H]- vesamicol binding to synaptic vesicles preparation from the electric organ of Torpedo californicaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVesicular acetylcholine transporter(Pacific electric ray)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50368834(CHEMBL1203907)
Affinity DataIC50: 25nMAssay Description:Inhibition of [3H]- vesamicol binding to synaptic vesicles preparation from the electric organ of Torpedo californicaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVesicular acetylcholine transporter(Pacific electric ray)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50046960(1'-(4-Bromo-benzyl)-4-phenyl-[1,3']bipiperidinyl-4...)
Affinity DataIC50: 25nMAssay Description:Inhibition of [3H]- vesamicol binding to synaptic vesicles preparation from the electric organ of Torpedo californicaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVesicular acetylcholine transporter(Pacific electric ray)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50039604((-)-1''-(3-Iodo-benzyl)-4-phenyl-[1,3'']bipiperidi...)
Affinity DataIC50: 26nMAssay Description:Inhibition of [3H]- vesamicol binding to synaptic vesicles preparation from the electric organ of Torpedo californicaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVesicular acetylcholine transporter(Pacific electric ray)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50368839(CHEMBL1203889)
Affinity DataIC50: 30nMAssay Description:Inhibition of [3H]- vesamicol binding to synaptic vesicles preparation from the electric organ of Torpedo californicaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVesicular acetylcholine transporter(Pacific electric ray)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50368832(CHEMBL1203917)
Affinity DataIC50: 31nMAssay Description:Inhibition of [3H]- vesamicol binding to synaptic vesicles preparation from the electric organ of Torpedo californicaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVesicular acetylcholine transporter(Pacific electric ray)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50018078(CHEMBL20943 | V-100 | 2-(4-Phenyl-piperidin-1-yl)-...)
Affinity DataIC50: 34nMAssay Description:Displacement of [3H]vesamicol from Vesamicol receptor of Torpedo californicaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVesicular acetylcholine transporter(Pacific electric ray)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50368836(CHEMBL1203885)
Affinity DataIC50: 34nMAssay Description:Inhibition of [3H]- vesamicol binding to synaptic vesicles preparation from the electric organ of Torpedo californicaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVesicular acetylcholine transporter(Pacific electric ray)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50368836(CHEMBL1203885)
Affinity DataIC50: 34nMAssay Description:Inhibition of [3H]- vesamicol binding to synaptic vesicles preparation from the electric organ of Torpedo californicaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVesicular acetylcholine transporter(Pacific electric ray)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50018094((1R,2R)-2-(4-Phenyl-piperidin-1-yl)-cyclohexanol |...)
Affinity DataIC50: 34nMAssay Description:Inhibition of [3H]- vesamicol binding to synaptic vesicles preparation from the electric organ of Torpedo californicaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50046947(CHEMBL172975)
Affinity DataIC50: 34nMAssay Description:Binding affinity to VAChTMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVesicular acetylcholine transporter(Pacific electric ray)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50009595(CHEMBL89812 | 1-(4-Bromo-phenyl)-3-(4-phenyl-piper...)
Affinity DataIC50: 36nMAssay Description:Inhibition of [3H]- vesamicol binding to synaptic vesicles preparation from the electric organ of Torpedo californicaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVesicular acetylcholine transporter(Pacific electric ray)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50009595(CHEMBL89812 | 1-(4-Bromo-phenyl)-3-(4-phenyl-piper...)
Affinity DataIC50: 36nMAssay Description:Inhibition of [3H]- vesamicol binding to synaptic vesicles preparation from the electric organ of Torpedo californicaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVesicular acetylcholine transporter(Pacific electric ray)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50009595(CHEMBL89812 | 1-(4-Bromo-phenyl)-3-(4-phenyl-piper...)
Affinity DataIC50: 36nMAssay Description:Displacement of [3H]vesamicol from Vesamicol receptor of Torpedo californicaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVesicular acetylcholine transporter(Pacific electric ray)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50368846(CHEMBL1203905)
Affinity DataIC50: 39nMAssay Description:Inhibition of [3H]- vesamicol binding to synaptic vesicles preparation from the electric organ of Torpedo californicaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50018078(CHEMBL20943 | V-100 | 2-(4-Phenyl-piperidin-1-yl)-...)
Affinity DataIC50: 40nMAssay Description:Inhibition of active transport of [3H]acetylcholine using purified Torpedo californica synaptic vesiclesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50018078(CHEMBL20943 | V-100 | 2-(4-Phenyl-piperidin-1-yl)-...)
Affinity DataIC50: 40nMAssay Description:Inhibition of active transport of [3H]acetylcholine using purified Torpedo californica synaptic vesiclesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50018117(CHEMBL21309 | 2-(4-Cyclohexyl-piperidin-1-yl)-cycl...)
Affinity DataIC50: 40nMAssay Description:Inhibition of active transport of [3H]acetylcholine using purified Torpedo californica synaptic vesiclesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVesicular acetylcholine transporter(Pacific electric ray)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50368844(CHEMBL1203881)
Affinity DataIC50: 42nMAssay Description:Inhibition of [3H]- vesamicol binding to synaptic vesicles preparation from the electric organ of Torpedo californicaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50183823(1-(3-bromobenzyl)-3-(4-phenylpiperazin-1-yl)piperi...)
Affinity DataIC50: 46nMAssay Description:Displacement of [3H]vesamicol from human VAChT transfected in PC12 cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50183817(1-(2-bromobenzyl)-3-(4-phenylpiperazin-1-yl)piperi...)
Affinity DataIC50: 47nMAssay Description:Displacement of [3H]vesamicol from human VAChT transfected in PC12 cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50018134(CHEMBL20499 | N-[6-Hydroxy-7-(4-phenyl-piperidin-1...)
Affinity DataIC50: 50nMAssay Description:Inhibition of active transport of [3H]acetylcholine using purified Torpedo californica synaptic vesiclesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50018090(CHEMBL20382 | N-[6-Hydroxy-7-(4-phenyl-piperidin-1...)
Affinity DataIC50: 50nMAssay Description:Inhibition of active transport of [3H]acetylcholine using purified Torpedo californica synaptic vesiclesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50018127(CHEMBL21271 | 1-[1-(2-Hydroxy-cyclohexyl)-4-phenyl...)
Affinity DataIC50: 50nMAssay Description:Inhibition of active transport of [3H]acetylcholine using purified Torpedo californica synaptic vesiclesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50018148(CHEMBL21151 | 3-(4-Phenyl-piperidin-1-yl)-1,2,3,4-...)
Affinity DataIC50: 50nMAssay Description:Inhibition of active transport of [3H]acetylcholine using purified Torpedo californica synaptic vesiclesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVesicular acetylcholine transporter(Pacific electric ray)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50368842(CHEMBL1203896)
Affinity DataIC50: 55nMAssay Description:Inhibition of [3H]- vesamicol binding to synaptic vesicles preparation from the electric organ of Torpedo californicaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50183813(1-benzyl-4-(4-phenylpiperazin-1-yl)piperidin-3-ol ...)
Affinity DataIC50: 57nMAssay Description:Displacement of [3H]vesamicol from human VAChT transfected in PC12 cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50183818(1-(3-bromobenzyl)-4-(4-phenylpiperazin-1-yl)piperi...)
Affinity DataIC50: 66nMAssay Description:Displacement of [3H]vesamicol from human VAChT transfected in PC12 cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50018125(CHEMBL21243 | 2-[4-(3-Phenyl-propyl)-piperidin-1-y...)
Affinity DataIC50: 70nMAssay Description:Inhibition of active transport of [3H]acetylcholine using purified Torpedo californica synaptic vesiclesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVesicular acetylcholine transporter(Pacific electric ray)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50009597(CHEMBL314574 | 1-(3-Iodo-phenyl)-3-(4-phenyl-piper...)
Affinity DataIC50: 73nMAssay Description:Displacement of [3H]vesamicol from Vesamicol receptor of Torpedo californicaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVesicular acetylcholine transporter(Pacific electric ray)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50009603(CHEMBL84797 | 1-(3-Bromo-phenyl)-3-(4-phenyl-piper...)
Affinity DataIC50: 73nMAssay Description:Displacement of [3H]vesamicol from Vesamicol receptor of Torpedo californicaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVesicular acetylcholine transporter(Pacific electric ray)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50368845(CHEMBL1203911)
Affinity DataIC50: 83nMAssay Description:Inhibition of [3H]- vesamicol binding to synaptic vesicles preparation from the electric organ of Torpedo californicaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50018098(CHEMBL21722 | 5-tert-Butyl-2-(4-phenyl-piperidin-1...)
Affinity DataIC50: 90nMAssay Description:Inhibition of active transport of [3H]acetylcholine using purified Torpedo californica synaptic vesiclesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50018080(CHEMBL20881 | 5-(2-Oxo-hexahydro-thieno[3,4-d]imid...)
Affinity DataIC50: 100nMAssay Description:Inhibition of active transport of [3H]acetylcholine using purified Torpedo californica synaptic vesiclesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50018110(CHEMBL21165 | 2-[4-(4-Chloro-phenyl)-piperidin-1-y...)
Affinity DataIC50: 100nMAssay Description:Inhibition of active transport of [3H]acetylcholine using purified Torpedo californica synaptic vesiclesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50018079(CHEMBL277630 | 5-Amino-3-(4-phenyl-piperidin-1-yl)...)
Affinity DataIC50: 100nMAssay Description:Inhibition of active transport of [3H]acetylcholine using purified Torpedo californica synaptic vesiclesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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