Compile Data Set for Download or QSAR
Report error Found 94 Enz. Inhib. hit(s) with Target = 'Urease subunit alpha'
TargetUrease subunit alpha(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Jishou University

Curated by ChEMBL
LigandPNGBDBM50449754(CHEMBL4167553)
Affinity DataIC50: 43nMAssay Description:Inhibition of Helicobacter pylori ATCC 43504 urease assessed as reduction in ammonia production preincubated for 1.5 hrs under cell free condition by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Minia University

LigandPNGBDBM221061(7-(4-Acetylpiperazin-1-yl)-1-cyclopropyl-6-fluoro-...)
Affinity DataIC50: 1.22E+3nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Minia University

LigandPNGBDBM221056(7-(4-Acetylpiperazin-1-yl)-1-cyclopropyl-6-fluoro-...)
Affinity DataIC50: 1.29E+3nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Bacillus pasteurii)
Hazara University

LigandPNGBDBM173607((Z)-2-((Z)-(Napthalen-1-ylmethylene)hydrazono)thia...)
Affinity DataIC50: 1.73E+3nMpH: 7.0Assay Description:This assay was modified from Berthelot assay and was employed for the determination of urease activity. The assay is based on the hydrolysis of urea ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Minia University

LigandPNGBDBM221063(7-(4-(3,4,5-Trimethoxy piperazin-1-yl))-1-cyclopro...)
Affinity DataIC50: 2.08E+3nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Minia University

LigandPNGBDBM221066((S)-9-Fluoro-3,7-dihydro-N-hydroxy-3-methyl-10-(4-...)
Affinity DataIC50: 2.20E+3nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Minia University

LigandPNGBDBM221051(7-(4-Acetylpiperazin-1-yl)-1-cyclopropyl-6-fluoro-...)
Affinity DataIC50: 2.22E+3nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Minia University

LigandPNGBDBM221050(N-acetyl ciprofloxacin)
Affinity DataIC50: 2.26E+3nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Bacillus pasteurii)
Hazara University

LigandPNGBDBM173602((Z)-2-((Z)-(1-(2-Bromo-4-nitrophenyl)ethylidene)hy...)
Affinity DataIC50: 2.31E+3nMpH: 7.0Assay Description:This assay was modified from Berthelot assay and was employed for the determination of urease activity. The assay is based on the hydrolysis of urea ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Minia University

LigandPNGBDBM221067((S)-9-Fluoro-3,7-dihydro-N,3-dimethyl-10-(4-methyl...)
Affinity DataIC50: 2.89E+3nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Minia University

LigandPNGBDBM221058(7-(4-(3,4,5-Trimetoxybenzoylpiperazin-1-yl))-1-cyc...)
Affinity DataIC50: 2.92E+3nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Escherichia coli)
University of Karachi

Curated by ChEMBL
LigandPNGBDBM50532158(CHEMBL4437765)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of bacterial urease using urea as substrate preincubated for 15 mins followed by substrate addition by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Escherichia coli)
University of Karachi

Curated by ChEMBL
LigandPNGBDBM50532155(CHEMBL4473387)
Affinity DataIC50: 4.97E+3nMAssay Description:Inhibition of bacterial urease using urea as substrate preincubated for 15 mins followed by substrate addition by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Escherichia coli)
University of Karachi

Curated by ChEMBL
LigandPNGBDBM50532153(CHEMBL4441391)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of bacterial urease using urea as substrate preincubated for 15 mins followed by substrate addition by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Bacillus pasteurii)
Hazara University

LigandPNGBDBM173604((Z)-2-((Z)-(4-Ethoxy-3-methoxybenzoylidine)hydrazo...)
Affinity DataIC50: 5.75E+3nMpH: 7.0Assay Description:This assay was modified from Berthelot assay and was employed for the determination of urease activity. The assay is based on the hydrolysis of urea ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Minia University

LigandPNGBDBM221053(7-(4-(3,4,5-Trimethoxybenzoylpiperazin-1-yl)-1-cyc...)
Affinity DataIC50: 7.17E+3nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Bacillus pasteurii)
Hazara University

LigandPNGBDBM173597((E)-2-((E)-(4-(Benzyloxy)-2-methoxybenzylidene)hyd...)
Affinity DataIC50: 7.30E+3nMpH: 7.0Assay Description:This assay was modified from Berthelot assay and was employed for the determination of urease activity. The assay is based on the hydrolysis of urea ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Bacillus pasteurii)
Hazara University

LigandPNGBDBM173595((E)-2((E)-(3-nitrobenzylidene)hydrazono)thiazolidi...)
Affinity DataIC50: 8.43E+3nMpH: 7.0Assay Description:This assay was modified from Berthelot assay and was employed for the determination of urease activity. The assay is based on the hydrolysis of urea ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Bacillus pasteurii)
Hazara University

LigandPNGBDBM60584((Z)-2-((Z)-(Napthalen-1-ylmethylene)hydrazono)thia...)
Affinity DataIC50: 8.81E+3nMpH: 7.0Assay Description:This assay was modified from Berthelot assay and was employed for the determination of urease activity. The assay is based on the hydrolysis of urea ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Bacillus pasteurii)
Hazara University

LigandPNGBDBM173590((E)-2-((E)-(3-Chloro-4-hydroxybenzylideno)thiazoli...)
Affinity DataIC50: 9.34E+3nMpH: 7.0Assay Description:This assay was modified from Berthelot assay and was employed for the determination of urease activity. The assay is based on the hydrolysis of urea ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Bacillus pasteurii)
Hazara University

LigandPNGBDBM181105(3-(3,4,5-Trimethoxybenzoyl)-(4-hydroxycoumarin) (9...)
Affinity DataIC50: 1.13E+4nMT: 2°CAssay Description:Reaction mixtures comprising one unit of urease enzyme (B. pasteurii) solution and 55 uL of buffers containing 100 mMol urea were incubated with 5 uL...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Bacillus pasteurii)
Hazara University

LigandPNGBDBM181103(3-Decanoyl-(4-hydroxycoumarin) (5))
Affinity DataIC50: 1.30E+4nMT: 2°CAssay Description:Reaction mixtures comprising one unit of urease enzyme (B. pasteurii) solution and 55 uL of buffers containing 100 mMol urea were incubated with 5 uL...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Escherichia coli)
University of Karachi

Curated by ChEMBL
LigandPNGBDBM50532164(CHEMBL4436232)
Affinity DataIC50: 1.37E+4nMAssay Description:Inhibition of bacterial urease using urea as substrate preincubated for 15 mins followed by substrate addition by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Escherichia coli)
University of Karachi

Curated by ChEMBL
LigandPNGBDBM50532156(CHEMBL4587997)
Affinity DataIC50: 1.45E+4nMAssay Description:Inhibition of bacterial urease using urea as substrate preincubated for 15 mins followed by substrate addition by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Bacillus pasteurii)
Hazara University

LigandPNGBDBM173593((E)-2((E)-(4-Hydroxybenzylidin)hydrazono)thiazolid...)
Affinity DataIC50: 1.46E+4nMpH: 7.0Assay Description:This assay was modified from Berthelot assay and was employed for the determination of urease activity. The assay is based on the hydrolysis of urea ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Escherichia coli)
University of Karachi

Curated by ChEMBL
LigandPNGBDBM50532150(CHEMBL4521852)
Affinity DataIC50: 1.63E+4nMAssay Description:Inhibition of bacterial urease using urea as substrate preincubated for 15 mins followed by substrate addition by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Escherichia coli)
University of Karachi

Curated by ChEMBL
LigandPNGBDBM50532162(CHEMBL4446149)
Affinity DataIC50: 1.69E+4nMAssay Description:Inhibition of bacterial urease using urea as substrate preincubated for 15 mins followed by substrate addition by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Bacillus pasteurii)
Hazara University

LigandPNGBDBM181104(3-Lauroyl-(4-hydroxycoumarin) (6))
Affinity DataIC50: 1.71E+4nMT: 2°CAssay Description:Reaction mixtures comprising one unit of urease enzyme (B. pasteurii) solution and 55 uL of buffers containing 100 mMol urea were incubated with 5 uL...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Escherichia coli)
University of Karachi

Curated by ChEMBL
LigandPNGBDBM50532144(CHEMBL4474805)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of bacterial urease using urea as substrate preincubated for 15 mins followed by substrate addition by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Minia University

LigandPNGBDBM221052(7-(4-Benzoylpiperazin-1-yl)-1-cyclopropyl-6-fluoro...)
Affinity DataIC50: 1.89E+4nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Minia University

LigandPNGBDBM221054(7-(4-((4-((E)-3-(Phenylacryloyl)phenylcarbamoyl)me...)
Affinity DataIC50: 1.93E+4nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Bacillus pasteurii)
Hazara University

LigandPNGBDBM50229993(thiocarbamide | thiocarbonic acid diamide | Thioha...)
Affinity DataIC50: 2.10E+4nMT: 2°CAssay Description:Reaction mixtures comprising one unit of urease enzyme (B. pasteurii) solution and 55 uL of buffers containing 100 mMol urea were incubated with 5 uL...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Bacillus pasteurii)
Hazara University

LigandPNGBDBM50229993(thiocarbamide | thiocarbonic acid diamide | Thioha...)
Affinity DataIC50: 2.13E+4nMpH: 7.0Assay Description:This assay was modified from Berthelot assay and was employed for the determination of urease activity. The assay is based on the hydrolysis of urea ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Bacillus pasteurii)
Hazara University

LigandPNGBDBM173592((E)-2-((E)-(3,5-Dichloro-2-hydroxybenzylidene)hydr...)
Affinity DataIC50: 2.67E+4nMpH: 7.0Assay Description:This assay was modified from Berthelot assay and was employed for the determination of urease activity. The assay is based on the hydrolysis of urea ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Bacillus pasteurii)
Hazara University

LigandPNGBDBM173589((E)-2((E)-(4-Nitrobenzylidene)hydrazono)thiazolidi...)
Affinity DataIC50: 2.69E+4nMpH: 7.0Assay Description:This assay was modified from Berthelot assay and was employed for the determination of urease activity. The assay is based on the hydrolysis of urea ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Escherichia coli)
University of Karachi

Curated by ChEMBL
LigandPNGBDBM50099857(acetohydroxamic acid | AHA | Acethydroxamsaeure | ...)
Affinity DataIC50: 2.92E+4nMAssay Description:Inhibition of bacterial urease using urea as substrate preincubated for 15 mins followed by substrate addition by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Bacillus pasteurii)
Hazara University

LigandPNGBDBM181106(3-(Methanesulfonoyl)-(4-hydroxycoumarin) (11))
Affinity DataIC50: 2.95E+4nMT: 2°CAssay Description:Reaction mixtures comprising one unit of urease enzyme (B. pasteurii) solution and 55 uL of buffers containing 100 mMol urea were incubated with 5 uL...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Bacillus pasteurii)
Hazara University

LigandPNGBDBM181102(3-Nonanoyl-(4-hydroxycoumarin) (4))
Affinity DataIC50: 3.09E+4nMT: 2°CAssay Description:Reaction mixtures comprising one unit of urease enzyme (B. pasteurii) solution and 55 uL of buffers containing 100 mMol urea were incubated with 5 uL...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Escherichia coli)
University of Karachi

Curated by ChEMBL
LigandPNGBDBM50532163(CHEMBL4557719)
Affinity DataIC50: 3.12E+4nMAssay Description:Inhibition of bacterial urease using urea as substrate preincubated for 15 mins followed by substrate addition by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Bacillus pasteurii)
Hazara University

LigandPNGBDBM173594((E)-2((E)-(3-Bromo-4,5-dimethoxybenzylidene)hydraz...)
Affinity DataIC50: 3.66E+4nMpH: 7.0Assay Description:This assay was modified from Berthelot assay and was employed for the determination of urease activity. The assay is based on the hydrolysis of urea ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Bacillus pasteurii)
Hazara University

LigandPNGBDBM173596((E)-2-((E)-(4-Hyrazoxy-3,5-dimethoxybenzylidene)hy...)
Affinity DataIC50: 3.79E+4nMpH: 7.0Assay Description:This assay was modified from Berthelot assay and was employed for the determination of urease activity. The assay is based on the hydrolysis of urea ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Bacillus pasteurii)
Hazara University

LigandPNGBDBM173600((E)-2-((E)-(4-(Benzyloxy)benzylidene)hydrazono)thi...)
Affinity DataIC50: 3.92E+4nMpH: 7.0Assay Description:This assay was modified from Berthelot assay and was employed for the determination of urease activity. The assay is based on the hydrolysis of urea ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Jishou University

Curated by ChEMBL
LigandPNGBDBM50099857(acetohydroxamic acid | AHA | Acethydroxamsaeure | ...)
Affinity DataIC50: 4.25E+4nMpH: 7.4 T: 2°CAssay Description:Briefly, 50 mL broth cultures (2.0 × 10^8 CFU/mL) were centrifuged (5000g, 4°C)to collect the bacteria, and after washing twice with phosph...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetUrease subunit alpha(Escherichia coli)
University of Karachi

Curated by ChEMBL
LigandPNGBDBM50532151(CHEMBL4568517)
Affinity DataIC50: 4.34E+4nMAssay Description:Inhibition of bacterial urease using urea as substrate preincubated for 15 mins followed by substrate addition by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Bacillus pasteurii)
Hazara University

LigandPNGBDBM173601((2Z)-2,20(Z)-(1,4-Phenylenebis(methane-1-yl-yliden...)
Affinity DataIC50: 4.39E+4nMpH: 7.0Assay Description:This assay was modified from Berthelot assay and was employed for the determination of urease activity. The assay is based on the hydrolysis of urea ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Bacillus pasteurii)
Hazara University

LigandPNGBDBM173588((E)-2-((E)-(2-Nitrobenzylidene)hydrazono)thiazolid...)
Affinity DataIC50: 4.75E+4nMpH: 7.0Assay Description:This assay was modified from Berthelot assay and was employed for the determination of urease activity. The assay is based on the hydrolysis of urea ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Bacillus pasteurii)
Hazara University

LigandPNGBDBM173598(4-((E)-((E)-(4-Oxothiazolidin-2-ylidene)hydrazono)...)
Affinity DataIC50: 4.85E+4nMpH: 7.0Assay Description:This assay was modified from Berthelot assay and was employed for the determination of urease activity. The assay is based on the hydrolysis of urea ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Bacillus pasteurii)
Hazara University

LigandPNGBDBM173603((E)-2-(E)-((1H-Indole-3-yl)methylene)hydrazono)thi...)
Affinity DataIC50: 5.14E+4nMpH: 7.0Assay Description:This assay was modified from Berthelot assay and was employed for the determination of urease activity. The assay is based on the hydrolysis of urea ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Bacillus pasteurii)
Hazara University

LigandPNGBDBM173591((E)-2-((E)-(2,3-Dimethoxybenzylidene)hydrazono)thi...)
Affinity DataIC50: 5.25E+4nMpH: 7.0Assay Description:This assay was modified from Berthelot assay and was employed for the determination of urease activity. The assay is based on the hydrolysis of urea ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Escherichia coli)
University of Karachi

Curated by ChEMBL
LigandPNGBDBM50532154(CHEMBL4592281)
Affinity DataIC50: 5.50E+4nMAssay Description:Inhibition of bacterial urease using urea as substrate preincubated for 15 mins followed by substrate addition by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Displayed 1 to 50 (of 94 total ) | Next | Last >>
Jump to: