Compile Data Set for Download or QSAR
Report error Found 96 Enz. Inhib. hit(s) with Target = 'Uracil-DNA glycosylase'
TargetUracil-DNA glycosylase(VACV)
University of Pennsylvania

US Patent
LigandPNGBDBM294522(US10112895, Compound 14 | N-[(2-benzyloxyphenyl)me...)
Affinity DataEC50:  7.90E+3nMpH: 7.5Assay Description:Processive DNA synthesis was assessed by two types of assays: the Rapid Plate Assay and the M13 assay. The Rapid Plate Assay was performed as previou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetUracil-DNA glycosylase(VACV)
University of Pennsylvania

US Patent
LigandPNGBDBM294507(US10112895, Compound 1 | 4-[[5-bromo-2-[(4- fluoro...)
Affinity DataEC50:  1.99E+4nMpH: 7.5Assay Description:Processive DNA synthesis was assessed by two types of assays: the Rapid Plate Assay and the M13 assay. The Rapid Plate Assay was performed as previou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetUracil-DNA glycosylase(VACV)
University of Pennsylvania

US Patent
LigandPNGBDBM294508(US10112895, Compound 2 | 5-[(2- benzyloxyphenyl)me...)
Affinity DataEC50:  1.00E+4nMpH: 7.5Assay Description:Processive DNA synthesis was assessed by two types of assays: the Rapid Plate Assay and the M13 assay. The Rapid Plate Assay was performed as previou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetUracil-DNA glycosylase(VACV)
University of Pennsylvania

US Patent
LigandPNGBDBM50431843(CHEMBL2347241 | US10112895, Compound 3)
Affinity DataEC50:  1.39E+4nMpH: 7.5Assay Description:Processive DNA synthesis was assessed by two types of assays: the Rapid Plate Assay and the M13 assay. The Rapid Plate Assay was performed as previou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetUracil-DNA glycosylase(VACV)
University of Pennsylvania

US Patent
LigandPNGBDBM294512(US10112895, Compound 4 | 5-[[2-[(4- chlorophenyl)m...)
Affinity DataEC50:  1.10E+4nMpH: 7.5Assay Description:Processive DNA synthesis was assessed by two types of assays: the Rapid Plate Assay and the M13 assay. The Rapid Plate Assay was performed as previou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetUracil-DNA glycosylase(VACV)
University of Pennsylvania

US Patent
LigandPNGBDBM294513(US10112895, Compound 5 | 5-[[2-[(2- chlorophenyl)m...)
Affinity DataEC50:  1.49E+4nMpH: 7.5Assay Description:Processive DNA synthesis was assessed by two types of assays: the Rapid Plate Assay and the M13 assay. The Rapid Plate Assay was performed as previou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetUracil-DNA glycosylase(VACV)
University of Pennsylvania

US Patent
LigandPNGBDBM294514(US10112895, Compound 6 | 5-[[2-[(4- fluorophenyl)m...)
Affinity DataEC50:  1.39E+4nMpH: 7.5Assay Description:Processive DNA synthesis was assessed by two types of assays: the Rapid Plate Assay and the M13 assay. The Rapid Plate Assay was performed as previou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetUracil-DNA glycosylase(VACV)
University of Pennsylvania

US Patent
LigandPNGBDBM294515(US10112895, Compound 7 | 5-[(2-benzyloxy-5-bromo- ...)
Affinity DataEC50:  1.10E+4nMpH: 7.5Assay Description:Processive DNA synthesis was assessed by two types of assays: the Rapid Plate Assay and the M13 assay. The Rapid Plate Assay was performed as previou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetUracil-DNA glycosylase(VACV)
University of Pennsylvania

US Patent
LigandPNGBDBM294516(US10112895, Compound 8 | 5-[[5-chloro-2-[(2- fluor...)
Affinity DataEC50:  1.10E+4nMpH: 7.5Assay Description:Processive DNA synthesis was assessed by two types of assays: the Rapid Plate Assay and the M13 assay. The Rapid Plate Assay was performed as previou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetUracil-DNA glycosylase(VACV)
University of Pennsylvania

US Patent
LigandPNGBDBM294517(US10112895, Compound 9 | 4-[[2-[(3- nitrophenyl)me...)
Affinity DataEC50:  1.33E+4nMpH: 7.5Assay Description:Processive DNA synthesis was assessed by two types of assays: the Rapid Plate Assay and the M13 assay. The Rapid Plate Assay was performed as previou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetUracil-DNA glycosylase(VACV)
University of Pennsylvania

US Patent
LigandPNGBDBM33154(SMR000231540 | cid_833990 | MLS000704391 | 4-[(2-p...)
Affinity DataEC50:  3.56E+4nMpH: 7.5Assay Description:Processive DNA synthesis was assessed by two types of assays: the Rapid Plate Assay and the M13 assay. The Rapid Plate Assay was performed as previou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetUracil-DNA glycosylase(VACV)
University of Pennsylvania

US Patent
LigandPNGBDBM294519(US10112895, Compound 11 | 2-[[2-[(3- nitrophenyl)m...)
Affinity DataEC50:  1.77E+4nMpH: 7.5Assay Description:Processive DNA synthesis was assessed by two types of assays: the Rapid Plate Assay and the M13 assay. The Rapid Plate Assay was performed as previou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetUracil-DNA glycosylase(VACV)
University of Pennsylvania

US Patent
LigandPNGBDBM294520(US10112895, Compound 12 | 4-[(2- benzyloxyphenyl)m...)
Affinity DataEC50:  1.94E+4nMpH: 7.5Assay Description:Processive DNA synthesis was assessed by two types of assays: the Rapid Plate Assay and the M13 assay. The Rapid Plate Assay was performed as previou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetUracil-DNA glycosylase(VACV)
University of Pennsylvania

US Patent
LigandPNGBDBM294521(US10112895, Compound 13 | N-[(2-benzyloxyphenyl)me...)
Affinity DataEC50:  1.44E+4nMpH: 7.5Assay Description:Processive DNA synthesis was assessed by two types of assays: the Rapid Plate Assay and the M13 assay. The Rapid Plate Assay was performed as previou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetUracil-DNA glycosylase(VACV)
University of Pennsylvania

US Patent
LigandPNGBDBM208055(3-(3-((3,5-Dichlorophenyl)thio)-6-methyl-1H-indol-...)
Affinity DataIC50: 42nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetUracil-DNA glycosylase(VACV)
University of Pennsylvania

US Patent
LigandPNGBDBM208056(US9233921, 24b | 2-(3-((3,5-Dichlorophenyl)thio)-6...)
Affinity DataIC50: 46nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetUracil-DNA glycosylase(VACV)
University of Pennsylvania

US Patent
LigandPNGBDBM208057(US9233921, 24c | 4-(3-((3,5-Dichlorophenyl)thio)-...)
Affinity DataIC50: 208nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetUracil-DNA glycosylase(VACV)
University of Pennsylvania

US Patent
LigandPNGBDBM208058(US9233921, 24d | 3-(3-((3,5-Dichlorophenyl)thio)-6...)
Affinity DataIC50: 244nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetUracil-DNA glycosylase(Human)
Johns Hopkins University

LigandPNGBDBM36453(CID25210526 | 6-[3-[(3-Carboxy-benzylidene)aminoox...)
Affinity DataIC50: 1.30E+3nMpH: 8.0Assay Description:Inhibition of human uracil DNA glycosylase using high-throughput fluorescent molecular beacon DNA substrate.More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetUracil-DNA glycosylase(VACV)
University of Pennsylvania

US Patent
LigandPNGBDBM33154(SMR000231540 | cid_833990 | MLS000704391 | 4-[(2-p...)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUracil-DNA glycosylase(VACV)
University of Pennsylvania

US Patent
LigandPNGBDBM208048( 3-((3,5-Dichlorophenyl)thio)-6-methyl-1H-indole-2...)
Affinity DataIC50: 7.00E+3nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetUracil-DNA glycosylase(Human)
Johns Hopkins University

LigandPNGBDBM50078333(6-(4-Octyl-phenylamino)-1H-pyrimidine-2,4-dione | ...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibitory potency against HSV-1 Uracil-DNA glycosylaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUracil-DNA glycosylase(VACV)
University of Pennsylvania

US Patent
LigandPNGBDBM208049(3-((3,5-Dichlorophenyl)thio)-6-ethyl-1H-indole-2-c...)
Affinity DataIC50: 9.00E+3nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetUracil-DNA glycosylase(Human)
Johns Hopkins University

LigandPNGBDBM50078341(1-(2-Hydroxy-ethyl)-6-(4-octyl-phenylamino)-1H-pyr...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory potency against HSV-1 Uracil-DNA glycosylaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUracil-DNA glycosylase(VACV)
University of Pennsylvania

US Patent
LigandPNGBDBM208051(6-Methyl-3-(phenylthio)-1H-indole-2-carboxylate |...)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetUracil-DNA glycosylase(Human)
Johns Hopkins University

LigandPNGBDBM50078334(1-(2-Methoxy-ethyl)-6-(4-octyl-phenylamino)-1H-pyr...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibitory potency against HSV-1 Uracil-DNA glycosylaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUracil-DNA glycosylase(VACV)
University of Pennsylvania

US Patent
LigandPNGBDBM208054(4-Methyl-3-((2,4,5-trichlorophenyl)thio)-1H-indole...)
Affinity DataIC50: 1.80E+4nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetUracil-DNA glycosylase(VACV)
University of Pennsylvania

US Patent
LigandPNGBDBM208038(Methyl 3-((4-chlorophenyl)thio)-6-methyl-1H-indole...)
Affinity DataIC50: 1.90E+4nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetUracil-DNA glycosylase(Human)
Johns Hopkins University

LigandPNGBDBM50078336(6-(4-Hexyl-phenylamino)-1-(2-hydroxy-ethyl)-1H-pyr...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory potency against HSV-1 UDG (Herpes Simplex virus type-I Uracil DNA glycosylase)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUracil-DNA glycosylase(VACV)
University of Pennsylvania

US Patent
LigandPNGBDBM208040(Methyl 3-((4-chlorophenyl)thio)-4-methyl-1H-indole...)
Affinity DataIC50: 2.10E+4nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetUracil-DNA glycosylase(VACV)
University of Pennsylvania

US Patent
LigandPNGBDBM208053(7-Methyl-3-((2,4,5-trichlorophenyl)thio)-1H-indole...)
Affinity DataIC50: 2.10E+4nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetUracil-DNA glycosylase(VACV)
University of Pennsylvania

US Patent
LigandPNGBDBM208039(Methyl 3-((4-chlorophenyl)thio)-7-methyl-1H-indole...)
Affinity DataIC50: 2.30E+4nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetUracil-DNA glycosylase(Human)
Johns Hopkins University

LigandPNGBDBM50078338(6-(4-Octyloxy-phenylamino)-1H-pyrimidine-2,4-dione...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibitory potency against HSV-1 Uracil-DNA glycosylaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUracil-DNA glycosylase(VACV)
University of Pennsylvania

US Patent
LigandPNGBDBM208052(6-Methyl-3-((2,4,5-trichlorophenyl)thio)-1H-indole...)
Affinity DataIC50: 2.50E+4nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetUracil-DNA glycosylase(Human)
Johns Hopkins University

LigandPNGBDBM50078340(6-(4-Hexyl-phenylamino)-1H-pyrimidine-2,4-dione | ...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory potency against HSV-1 UDG (Herpes Simplex virus type-I Uracil DNA glycosylase)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUracil-DNA glycosylase(Human)
Johns Hopkins University

LigandPNGBDBM50078339(6-(4-Hexyloxy-phenylamino)-1H-pyrimidine-2,4-dione...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory potency against HSV-1 UDG (Herpes Simplex virus type-I Uracil DNA glycosylase)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUracil-DNA glycosylase(VACV)
University of Pennsylvania

US Patent
LigandPNGBDBM208043(6-Methyl-3-((4-(trifluoromethyl)phenyl)thio)-1H-in...)
Affinity DataIC50: 3.30E+4nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetUracil-DNA glycosylase(VACV)
University of Pennsylvania

US Patent
LigandPNGBDBM208045(3-((3,4-Dichlorophenyl)thio)-6-methyl-1H-indole-2-...)
Affinity DataIC50: 3.40E+4nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetUracil-DNA glycosylase(VACV)
University of Pennsylvania

US Patent
LigandPNGBDBM50343395(10-(cyclohexylamino)-12-[(2-hydroxyethyl)amino]-15...)
Affinity DataIC50: 3.41E+4nMAssay Description:Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUracil-DNA glycosylase(VACV)
University of Pennsylvania

US Patent
LigandPNGBDBM208046(3-((3,4-Dichlorophenyl)thio)-7-methyl-1H-indole-2-...)
Affinity DataIC50: 3.50E+4nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetUracil-DNA glycosylase(Human)
Johns Hopkins University

LigandPNGBDBM50078335(6-(4-Decyl-phenylamino)-1H-pyrimidine-2,4-dione | ...)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibitory potency against HSV-1 Uracil-DNA glycosylaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUracil-DNA glycosylase(VACV)
University of Pennsylvania

US Patent
LigandPNGBDBM208032(3-((4-Chlorophenyl)thio)-6-ethyl-1H-indole-2-carbo...)
Affinity DataIC50: 3.60E+4nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetUracil-DNA glycosylase(VACV)
University of Pennsylvania

US Patent
LigandPNGBDBM208044(3-((2,4-Dichlorophenyl)thio)-6-methyl-1H-indole-2-...)
Affinity DataIC50: 3.70E+4nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetUracil-DNA glycosylase(VACV)
University of Pennsylvania

US Patent
LigandPNGBDBM80984(4-chloro-2-[(5-chloro-2-hydroxyphenyl)thio]phenol ...)
Affinity DataIC50: 3.85E+4nMAssay Description:Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUracil-DNA glycosylase(VACV)
University of Pennsylvania

US Patent
LigandPNGBDBM208037(Methyl 3-((4-chlorophenyl)thio)-1-ethyl-5-methyl-1...)
Affinity DataIC50: 3.90E+4nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetUracil-DNA glycosylase(VACV)
University of Pennsylvania

US Patent
LigandPNGBDBM208031(6-Fluoro-3-((4-chlorophenyl)thio)-1H-indole-2-carb...)
Affinity DataIC50: 4.00E+4nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetUracil-DNA glycosylase(Human)
Johns Hopkins University

LigandPNGBDBM36452(CID25210531 | 6-[[(3-Carboxy-benzylidene)-aminooxy...)
Affinity DataIC50: 4.00E+4nMpH: 8.0Assay Description:Inhibition of human uracil DNA glycosylase using high-throughput fluorescent molecular beacon DNA substrate.More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetUracil-DNA glycosylase(VACV)
University of Pennsylvania

US Patent
LigandPNGBDBM208047(3-((3,4-Dichlorophenyl)thio)-6-ethyl-1H-indole-2-c...)
Affinity DataIC50: 4.20E+4nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetUracil-DNA glycosylase(VACV)
University of Pennsylvania

US Patent
LigandPNGBDBM208050(3-((3,5-Dichlorophenyl)thio)-1H-indole-2-carboxyli...)
Affinity DataIC50: 4.30E+4nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetUracil-DNA glycosylase(VACV)
University of Pennsylvania

US Patent
LigandPNGBDBM208027(3-((4-Chlorophenyl)thio)-5-methyl-1H-indole-2-carb...)
Affinity DataIC50: 4.60E+4nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
In DepthDetails
US Patent

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