Report error Found 1235 Enz. Inhib. hit(s) with Target = 'Ubiquitin carboxyl-terminal hydrolase 7'
Affinity DataEC50: 4.20E+3nMAssay Description:Inhibition of recombinant USP7 expressed in Sf9 cells by Ub-CHOP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: >3.16E+4nMAssay Description:Inhibition of recombinant USP7 expressed in Sf9 cells by Ub-CHOP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 6.90E+3nMAssay Description:Inhibition of recombinant USP7 expressed in Sf9 cells by Ub-CHOP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 8.00E+3nMAssay Description:Inhibition of recombinant USP7 expressed in Sf9 cells by Ub-CHOP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.20E+3nMAssay Description:Inhibition of recombinant USP7 expressed in Sf9 cells by Ub-CHOP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.70E+3nMAssay Description:Inhibition of recombinant USP7 expressed in Sf9 cells by Ub-CHOP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 7.80E+3nMAssay Description:Inhibition of recombinant USP7 expressed in Sf9 cells by Ub-CHOP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 380nMAssay Description:Inhibition of recombinant USP7 expressed in Sf9 cells by Ub-CHOP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 430nMAssay Description:Inhibition of recombinant USP7 expressed in Sf9 cells by Ub-CHOP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 400nMAssay Description:Inhibition of recombinant USP7 expressed in Sf9 cells by Ub-CHOP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.90E+4nMAssay Description:Inhibition of recombinant USP7 expressed in Sf9 cells by Ub-CHOP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 380nMAssay Description:Inhibition of recombinant USP7 expressed in Sf9 cells by Ub-CHOP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 420nMAssay Description:Inhibition of recombinant USP7 expressed in Sf9 cells by Ub-CHOP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.01E+4nMAssay Description:Inhibition of USP7 in multiple myeloma cells (unknown origin) by immunohistochemistryMore data for this Ligand-Target Pair
Affinity DataEC50: 4.20E+3nMAssay Description:Inhibition of USP7 in multiple myeloma cells (unknown origin) by immunohistochemistryMore data for this Ligand-Target Pair
Affinity DataEC50: 4.20E+3nMAssay Description:Inhibition of USP7 (unknown origin) by Ub-CHOP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 8.00E+3nMAssay Description:Inhibition of USP7 (unknown origin) by Ub-CHOP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.65E+4nMAssay Description:Inhibition of USP7 in human SJSA cells assessed as increase in ubiquitinated MDM2 level after 16 hrs in presence of MG132 by MSD assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.58E+3nMAssay Description:Inhibition of USP7 in human SJSA cells assessed as increase in ubiquitinated MDM2 level after 16 hrs in presence of MG132 by MSD assayMore data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of USP7 in human SJSA cells assessed as increase in ubiquitinated MDM2 level after 16 hrs in presence of MG132 by MSD assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.20E+4nMAssay Description:Binding affinity to human His-tagged and [15N-13C-2H], delta1[13CH3]-Ile, [13CH3]-Leu/Val and [13CH3]-Met-labeled USP7-catalytic domain (208 to 554 r...More data for this Ligand-Target Pair
Affinity DataKd: 1.20E+4nMAssay Description:Binding affinity to human His-tagged and [15N-13C-2H], delta1[13CH3]-Ile, [13CH3]-Leu/Val and [13CH3]-Met-labeled USP7-catalytic domain (208 to 554 r...More data for this Ligand-Target Pair
Affinity DataKd: 4.71E+5nMAssay Description:Binding affinity to recombinant human N-terminal His6-tagged USP7 catalytic domain (213 to 548 residues) expressed in baculovirus infected Sf21 insec...More data for this Ligand-Target Pair
Affinity DataEC50: 320nMAssay Description:Inhibition of USP7 in human HCT116 cells using ubiquitin-propargylamine probe as substrate incubated for 2 hrs followed by substrate addition measure...More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataEC50: 3.75E+4nMAssay Description:Inhibition of USP7 in human SJSA cells assessed as increase in ubiquitinated MDM2 level after 16 hrs in presence of MG132 by MSD assayMore data for this Ligand-Target Pair
Affinity DataEC50: 300nMAssay Description:Inhibition of USP7 in human SJSA cells assessed as increase in ubiquitinated MDM2 level after 16 hrs in presence of MG132 by MSD assayMore data for this Ligand-Target Pair
Affinity DataEC50: 250nMAssay Description:Inhibition of USP7 in human RKO cells transfected with p53 luciferase reporter vector assessed as increase in p53-dependent luciferase activity measu...More data for this Ligand-Target Pair
Affinity DataEC50: 33nMAssay Description:Inhibition of USP7 in human RKO cells transfected with p53 luciferase reporter vector assessed as increase in p53-dependent luciferase activity measu...More data for this Ligand-Target Pair
Affinity DataEC50: 130nMAssay Description:Inhibition of USP7 in human RKO cells transfected with p53 luciferase reporter vector assessed as increase in p53-dependent luciferase activity measu...More data for this Ligand-Target Pair
Affinity DataEC50: 560nMAssay Description:Inhibition of USP7 in human RKO cells transfected with p53 luciferase reporter vector assessed as increase in p53-dependent luciferase activity measu...More data for this Ligand-Target Pair
Affinity DataEC50: 180nMAssay Description:Inhibition of USP7 in human RKO cells transfected with p53 luciferase reporter vector assessed as increase in p53-dependent luciferase activity measu...More data for this Ligand-Target Pair
Affinity DataEC50: 400nMAssay Description:Inhibition of USP7 in human RKO cells transfected with p53 luciferase reporter vector assessed as increase in p53-dependent luciferase activity measu...More data for this Ligand-Target Pair
Affinity DataEC50: 320nMAssay Description:Inhibition of USP7 in human RKO cells transfected with p53 luciferase reporter vector assessed as increase in p53-dependent luciferase activity measu...More data for this Ligand-Target Pair
Affinity DataEC50: 150nMAssay Description:Inhibition of USP7 in human RKO cells transfected with p53 luciferase reporter vector assessed as increase in p53-dependent luciferase activity measu...More data for this Ligand-Target Pair
Affinity DataEC50: 150nMAssay Description:Inhibition of USP7 in human RKO cells transfected with p53 luciferase reporter vector assessed as increase in p53-dependent luciferase activity measu...More data for this Ligand-Target Pair
Affinity DataEC50: 170nMAssay Description:Inhibition of USP7 in human RKO cells transfected with p53 luciferase reporter vector assessed as increase in p53-dependent luciferase activity measu...More data for this Ligand-Target Pair
Affinity DataEC50: 65nMAssay Description:Inhibition of USP7 in human RKO cells transfected with p53 luciferase reporter vector assessed as increase in p53-dependent luciferase activity measu...More data for this Ligand-Target Pair
Affinity DataEC50: 42nMAssay Description:Inhibition of USP7 in human RKO cells transfected with p53 luciferase reporter vector assessed as increase in p53-dependent luciferase activity measu...More data for this Ligand-Target Pair
Affinity DataEC50: 1.20E+3nMAssay Description:Inhibition of USP7 in human RKO cells transfected with p53 luciferase reporter vector assessed as increase in p53-dependent luciferase activity measu...More data for this Ligand-Target Pair
Affinity DataEC50: 280nMAssay Description:Inhibition of USP7 in human RKO cells transfected with p53 luciferase reporter vector assessed as increase in p53-dependent luciferase activity measu...More data for this Ligand-Target Pair
Affinity DataEC50: 60nMAssay Description:Inhibition of USP7 in human RKO cells transfected with p53 luciferase reporter vector assessed as increase in p53-dependent luciferase activity measu...More data for this Ligand-Target Pair
Affinity DataEC50: 35nMAssay Description:Inhibition of USP7 in human RKO cells transfected with p53 luciferase reporter vector assessed as increase in p53-dependent luciferase activity measu...More data for this Ligand-Target Pair
Affinity DataEC50: 210nMAssay Description:Inhibition of USP7 in human RKO cells transfected with p53 luciferase reporter vector assessed as increase in p53-dependent luciferase activity measu...More data for this Ligand-Target Pair
Affinity DataEC50: 60nMAssay Description:Inhibition of USP7 in human RKO cells transfected with p53 luciferase reporter vector assessed as increase in p53-dependent luciferase activity measu...More data for this Ligand-Target Pair
Affinity DataEC50: 25nMAssay Description:Inhibition of USP7 in human RKO cells transfected with p53 luciferase reporter vector assessed as increase in p53-dependent luciferase activity measu...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of human USP7 using Ub-EKL as substrateMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of human USP7 using Ub-EKL as substrateMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of human USP7 using Ub-EKL as substrateMore data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+3nMAssay Description:Inhibition of human USP7 using Ub-EKL as substrateMore data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+3nMAssay Description:Inhibition of human USP7 using Ub-EKL as substrateMore data for this Ligand-Target Pair
