Compile Data Set for Download or QSAR
Report error Found 382 Enz. Inhib. hit(s) with Target = 'Ubiquitin carboxyl-terminal hydrolase 28'
LigandPNGBDBM708839(US20240425513, Example 20)
Ligand Info
In DepthDetails

LigandPNGBDBM50618514(CHEMBL5401467)
Affinity DataIC50: 40nMAssay Description:Inhibition of USP28 (149 to 703 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) using Ub-AMC as substrate by fluorescence based a...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM708840(US20240425513, Example 21)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM708841(US20240425513, Example 22)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM708843(US20240425513, Example 24)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM708844(US20240425513, Example 25)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM708845(US20240425513, Example 26)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM708846(US20240425513, Example 27)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM708847(US20240425513, Example 28)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM708848(US20240425513, Example 29)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM708851(US20240425513, Example 32)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM708852(US20240425513, Example 33)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM708853(US20240425513, Example 34)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM708854(US20240425513, Example 35)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM708855(US20240425513, Example 36)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM708856(US20240425513, Example 37)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM708857(US20240425513, Example 38)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM708858(US20240425513, Example 39)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM708859(US20240425513, Example 40)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM708860(US20240425513, Example 41)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM708862(US20240425513, Example 43)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM708863(US20240425513, Example 44)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM50618513(CHEMBL5431014)
Affinity DataIC50: 100nMAssay Description:Inhibition of USP28 (149 to 703 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) using Ub-AMC as substrate by fluorescence based a...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50618502(CHEMBL5398929)
Affinity DataIC50: 110nMAssay Description:Inhibition of USP28 (149 to 703 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) using Ub-AMC as substrate by fluorescence based a...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50618512(CHEMBL5402874)
Affinity DataIC50: 150nMAssay Description:Inhibition of USP28 (149 to 703 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) using Ub-AMC as substrate by fluorescence based a...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM478023(US10889592, Compound I-3 | US11325917, Compound I-...)
Affinity DataIC50: 200nMAssay Description:USP28: Each assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Cor...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM478025(US10889592, Compound I-5 | US10889592, Compound I-...)
Affinity DataIC50: 200nMAssay Description:USP28: Each assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Cor...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM478026(US10889592, Compound I-6)
Affinity DataIC50: 200nMAssay Description:USP28: Each assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Cor...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM478027(US10889592, Compound I-7 | US11325917, Compound I-...)
Affinity DataIC50: 200nMAssay Description:USP28: Each assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Cor...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM478029(US10889592, Compound I-10)
Affinity DataIC50: 200nMAssay Description:USP28: Each assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Cor...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM478038(US10889592, Compound I-15)
Affinity DataIC50: 200nMAssay Description:USP28: Each assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Cor...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM478041(US10889592, Compound I-20)
Affinity DataIC50: 200nMAssay Description:USP28: Each assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Cor...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM481935(US10913753, Compound I-2)
Affinity DataIC50: 200nMAssay Description:USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM481937(US10913753, Compound I-4)
Affinity DataIC50: 200nMAssay Description:USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM481939(US10913753, Compound I-6)
Affinity DataIC50: 200nMAssay Description:USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM481941(US10913753, Compound I-8)
Affinity DataIC50: 200nMAssay Description:USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM481945(US10913753, Compound I-12)
Affinity DataIC50: 200nMAssay Description:USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM481946(US10913753, Compound I-13 | US20230365583, Compoun...)
Affinity DataIC50: 200nMAssay Description:USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM481947(US10913753, Compound I-14)
Affinity DataIC50: 200nMAssay Description:USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM481948(US10913753, Compound I-15 | US10913753, Compound I...)
Affinity DataIC50: 200nMAssay Description:USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM481949(US10913753, Compound I-16)
Affinity DataIC50: 200nMAssay Description:USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM481951(US10913753, Compound I-18)
Affinity DataIC50: 200nMAssay Description:USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM481952(US10913753, Compound I-19)
Affinity DataIC50: 200nMAssay Description:USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM481954(US10913753, Compound I-21)
Affinity DataIC50: 200nMAssay Description:USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM481955(US10913753, Compound I-22)
Affinity DataIC50: 200nMAssay Description:USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM481967(US10913753, Compound I-34)
Affinity DataIC50: 200nMAssay Description:USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM481968(US10913753, Compound I-35)
Affinity DataIC50: 200nMAssay Description:USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM481969(US10913753, Compound I-36)
Affinity DataIC50: 200nMAssay Description:USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM481970(US10913753, Compound I-37)
Affinity DataIC50: 200nMAssay Description:USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM481974(US10913753, Compound I-41)
Affinity DataIC50: 200nMAssay Description:USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...More data for this Ligand-Target Pair
In DepthDetails
US Patent

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