Compile Data Set for Download or QSAR
Report error Found 56 Enz. Inhib. hit(s) with Target = 'Ubiquitin carboxyl-terminal hydrolase 21'
LigandPNGBDBM50612991(CHEMBL5279102)
Affinity DataEC50:  0.0166nMAssay Description:Inhibition of full-length human USP21 transfected in human HEK293T cells co-transfected with NF-kappaB reporter firefly luciferase plasmid assessed a...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50612992(CHEMBL5285026)
Affinity DataEC50: >1.00E+5nMAssay Description:Binding affinity to C-terminally NanoLuc HiBiT-tagged USP21 transfected in human HEK293T cells ssessed as thermal stability at 49 degreeC incubated f...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50612991(CHEMBL5279102)
Affinity DataEC50:  0.0950nMAssay Description:Binding affinity to C-terminally NanoLuc HiBiT-tagged USP21 transfected in human HEK293T cells ssessed as thermal stability at 49 degreeC incubated f...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50612991(CHEMBL5279102)
Affinity DataKd:  2.20nMAssay Description:Binding affinity to recombinant human N-terminal His6-tagged USP21 (209 to 563 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissoci...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50612988(CHEMBL5286335)
Affinity DataKd:  5.80nMAssay Description:Binding affinity to recombinant human N-terminal His6-tagged USP21 (209 to 563 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissoci...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50612971(CHEMBL5273043)
Affinity DataKd:  7.90nMAssay Description:Binding affinity to recombinant human N-terminal His6-tagged USP21 (209 to 563 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissoci...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50612991(CHEMBL5279102)
Affinity DataIC50: 2nMAssay Description:Inhibition of human USP21 using ubiquitin rhodamine 110 110 as substrate preincubated for 15 to 20 mins followed by enzyme addition and measured afte...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50612991(CHEMBL5279102)
Affinity DataIC50: 6nMAssay Description:Inhibition of human full length USP21 using Btn-Ahx-PNIRFLD-K(Ubi)-LPQQT-GD-amide as substrate preincubated for 15 to 20 mins followed by substrate a...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50612990(CHEMBL5268828)
Affinity DataIC50: 8nMAssay Description:Inhibition of human USP21 using ubiquitin rhodamine 110 110 as substrate preincubated for 15 to 20 mins followed by enzyme addition and measured afte...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50612988(CHEMBL5286335)
Affinity DataIC50: 11nMAssay Description:Inhibition of human USP21 using ubiquitin rhodamine 110 110 as substrate preincubated for 15 to 20 mins followed by enzyme addition and measured afte...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50612990(CHEMBL5268828)
Affinity DataIC50: 12nMAssay Description:Inhibition of human full length USP21 using Btn-Ahx-PNIRFLD-K(Ubi)-LPQQT-GD-amide as substrate preincubated for 15 to 20 mins followed by substrate a...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50612988(CHEMBL5286335)
Affinity DataIC50: 18nMAssay Description:Inhibition of human full length USP21 using Btn-Ahx-PNIRFLD-K(Ubi)-LPQQT-GD-amide as substrate preincubated for 15 to 20 mins followed by substrate a...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50612984(CHEMBL5277351)
Affinity DataIC50: 28nMAssay Description:Inhibition of human USP21 using ubiquitin rhodamine 110 110 as substrate preincubated for 15 to 20 mins followed by enzyme addition and measured afte...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50612984(CHEMBL5277351)
Affinity DataIC50: 32nMAssay Description:Inhibition of human full length USP21 using Btn-Ahx-PNIRFLD-K(Ubi)-LPQQT-GD-amide as substrate preincubated for 15 to 20 mins followed by substrate a...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50612986(CHEMBL5267932)
Affinity DataIC50: 32nMAssay Description:Inhibition of human USP21 using ubiquitin rhodamine 110 110 as substrate preincubated for 15 to 20 mins followed by enzyme addition and measured afte...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50612981(CHEMBL5275560)
Affinity DataIC50: 32nMAssay Description:Inhibition of human USP21 using ubiquitin rhodamine 110 110 as substrate preincubated for 15 to 20 mins followed by enzyme addition and measured afte...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50612987(CHEMBL5271965)
Affinity DataIC50: 36nMAssay Description:Inhibition of human USP21 using ubiquitin rhodamine 110 110 as substrate preincubated for 15 to 20 mins followed by enzyme addition and measured afte...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50612989(CHEMBL5266176)
Affinity DataIC50: 45nMAssay Description:Inhibition of human USP21 using ubiquitin rhodamine 110 110 as substrate preincubated for 15 to 20 mins followed by enzyme addition and measured afte...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50612987(CHEMBL5271965)
Affinity DataIC50: 45nMAssay Description:Inhibition of human full length USP21 using Btn-Ahx-PNIRFLD-K(Ubi)-LPQQT-GD-amide as substrate preincubated for 15 to 20 mins followed by substrate a...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50612983(CHEMBL5279700)
Affinity DataIC50: 65nMAssay Description:Inhibition of human full length USP21 using Btn-Ahx-PNIRFLD-K(Ubi)-LPQQT-GD-amide as substrate preincubated for 15 to 20 mins followed by substrate a...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50612982(CHEMBL5280287)
Affinity DataIC50: 72nMAssay Description:Inhibition of human full length USP21 using Btn-Ahx-PNIRFLD-K(Ubi)-LPQQT-GD-amide as substrate preincubated for 15 to 20 mins followed by substrate a...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50612979(CHEMBL5274527)
Affinity DataIC50: 72nMAssay Description:Inhibition of human USP21 using ubiquitin rhodamine 110 110 as substrate preincubated for 15 to 20 mins followed by enzyme addition and measured afte...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50612981(CHEMBL5275560)
Affinity DataIC50: 73nMAssay Description:Inhibition of human full length USP21 using Btn-Ahx-PNIRFLD-K(Ubi)-LPQQT-GD-amide as substrate preincubated for 15 to 20 mins followed by substrate a...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50612980(CHEMBL5275910)
Affinity DataIC50: 74nMAssay Description:Inhibition of human full length USP21 using Btn-Ahx-PNIRFLD-K(Ubi)-LPQQT-GD-amide as substrate preincubated for 15 to 20 mins followed by substrate a...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50612986(CHEMBL5267932)
Affinity DataIC50: 84nMAssay Description:Inhibition of human full length USP21 using Btn-Ahx-PNIRFLD-K(Ubi)-LPQQT-GD-amide as substrate preincubated for 15 to 20 mins followed by substrate a...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50612989(CHEMBL5266176)
Affinity DataIC50: 100nMAssay Description:Inhibition of human full length USP21 using Btn-Ahx-PNIRFLD-K(Ubi)-LPQQT-GD-amide as substrate preincubated for 15 to 20 mins followed by substrate a...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50612979(CHEMBL5274527)
Affinity DataIC50: 119nMAssay Description:Inhibition of human full length USP21 using Btn-Ahx-PNIRFLD-K(Ubi)-LPQQT-GD-amide as substrate preincubated for 15 to 20 mins followed by substrate a...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50612977(CHEMBL5278034)
Affinity DataIC50: 221nMAssay Description:Inhibition of human USP21 using ubiquitin rhodamine 110 110 as substrate preincubated for 15 to 20 mins followed by enzyme addition and measured afte...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50612977(CHEMBL5278034)
Affinity DataIC50: 754nMAssay Description:Inhibition of human full length USP21 using Btn-Ahx-PNIRFLD-K(Ubi)-LPQQT-GD-amide as substrate preincubated for 15 to 20 mins followed by substrate a...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50612974(CHEMBL5269090)
Affinity DataIC50: 5.87E+3nMAssay Description:Inhibition of human full length USP21 using Btn-Ahx-PNIRFLD-K(Ubi)-LPQQT-GD-amide as substrate preincubated for 15 to 20 mins followed by substrate a...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50612974(CHEMBL5269090)
Affinity DataIC50: 7.14E+3nMAssay Description:Inhibition of human USP21 using ubiquitin rhodamine 110 110 as substrate preincubated for 15 to 20 mins followed by enzyme addition and measured afte...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50538571(CHEMBL4635160)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human GST-tagged USP21 CD (196 to 565 residues) expressed in Escherichia coli assessed as cleavage of Ubiquitin-Rhodamine110-glycine to...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50612971(CHEMBL5273043)
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of human full length USP21 using Btn-Ahx-PNIRFLD-K(Ubi)-LPQQT-GD-amide as substrate preincubated for 15 to 20 mins followed by substrate a...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50612975(CHEMBL5269490)
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of human full length USP21 using Btn-Ahx-PNIRFLD-K(Ubi)-LPQQT-GD-amide as substrate preincubated for 15 to 20 mins followed by substrate a...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50612992(CHEMBL5285026)
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of human full length USP21 using Btn-Ahx-PNIRFLD-K(Ubi)-LPQQT-GD-amide as substrate preincubated for 15 to 20 mins followed by substrate a...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50612992(CHEMBL5285026)
Affinity DataIC50: 1.62E+4nMAssay Description:Inhibition of human USP21 using ubiquitin rhodamine 110 110 as substrate preincubated for 15 to 20 mins followed by enzyme addition and measured afte...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50436152(SPONGIACIDIN C)
Affinity DataIC50: 1.66E+4nMAssay Description:Inhibition of core catalytic domain of USP21 (unknown origin) using ubiquitin-Rh110 as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50612975(CHEMBL5269490)
Affinity DataIC50: 2.02E+4nMAssay Description:Inhibition of human USP21 using ubiquitin rhodamine 110 110 as substrate preincubated for 15 to 20 mins followed by enzyme addition and measured afte...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50612985(CHEMBL5284472)
Affinity DataIC50: 2.15E+4nMAssay Description:Inhibition of human full length USP21 using Btn-Ahx-PNIRFLD-K(Ubi)-LPQQT-GD-amide as substrate preincubated for 15 to 20 mins followed by substrate a...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50612971(CHEMBL5273043)
Affinity DataIC50: 2.25E+4nMAssay Description:Inhibition of human USP21 using ubiquitin aminoluciferin as substrate incubated for 25 mins by luminescence based assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50612971(CHEMBL5273043)
Affinity DataIC50: 2.25E+4nMAssay Description:Inhibition of human USP21 using ubiquitin rhodamine 110 110 as substrate preincubated for 15 to 20 mins followed by enzyme addition and measured afte...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50612985(CHEMBL5284472)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human USP21 using ubiquitin rhodamine 110 110 as substrate preincubated for 15 to 20 mins followed by enzyme addition and measured afte...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50612983(CHEMBL5279700)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human USP21 using ubiquitin rhodamine 110 110 as substrate preincubated for 15 to 20 mins followed by enzyme addition and measured afte...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50612982(CHEMBL5280287)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human USP21 using ubiquitin rhodamine 110 110 as substrate preincubated for 15 to 20 mins followed by enzyme addition and measured afte...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50612978(CHEMBL5269199)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human USP21 using ubiquitin rhodamine 110 110 as substrate preincubated for 15 to 20 mins followed by enzyme addition and measured afte...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50612976(CHEMBL5266959)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human USP21 using ubiquitin rhodamine 110 110 as substrate preincubated for 15 to 20 mins followed by enzyme addition and measured afte...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50612973(CHEMBL5266408)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human USP21 using ubiquitin rhodamine 110 110 as substrate preincubated for 15 to 20 mins followed by enzyme addition and measured afte...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50612972(CHEMBL5271797)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human USP21 using ubiquitin rhodamine 110 110 as substrate preincubated for 15 to 20 mins followed by enzyme addition and measured afte...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50612978(CHEMBL5269199)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human full length USP21 using Btn-Ahx-PNIRFLD-K(Ubi)-LPQQT-GD-amide as substrate preincubated for 15 to 20 mins followed by substrate a...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50612976(CHEMBL5266959)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human full length USP21 using Btn-Ahx-PNIRFLD-K(Ubi)-LPQQT-GD-amide as substrate preincubated for 15 to 20 mins followed by substrate a...More data for this Ligand-Target Pair
In DepthDetails
PubMed
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