Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase ITK/TSK [357-620,Y512E]'
LigandPNGBDBM213220(N-[(3S)-1-Acryloyl-3-pyrrolidinyl]-4-{[cis-2,6-dim...)
Affinity DataIC50: 5nMAssay Description:This assay is based on the binding and displacement of Alexa-fluor 647-labeled ATP-competitive kinase inhibitor tracer 236. Binding of the tracer is ...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50062938(CHEMBL3397909 | N-[(3S)-1-Acryloyl-3-pyrrolidinyl]...)
Affinity DataIC50: 5nMAssay Description:This assay is based on the binding and displacement of Alexa-fluor 647-labeled ATP-competitive kinase inhibitor tracer 236. Binding of the tracer is ...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM213221((S)-1-(3-((4-(Piperidin-1-ylmethyl)-6-(thiazolo[5,...)
Affinity DataIC50: 6.30nMAssay Description:This assay is based on the binding and displacement of Alexa-fluor 647-labeled ATP-competitive kinase inhibitor tracer 236. Binding of the tracer is ...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM213223(1-((S)-3-((4-((((R)-3,3-Dimethylbutan-2-yl)amino)m...)
Affinity DataIC50: 7.90nMAssay Description:This assay is based on the binding and displacement of Alexa-fluor 647-labeled ATP-competitive kinase inhibitor tracer 236. Binding of the tracer is ...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM213219((S)-1-(3-((4-(Morpholinomethyl)-6-(thiazolo[5,4-b]...)
Affinity DataIC50: 13nMAssay Description:This assay is based on the binding and displacement of Alexa-fluor 647-labeled ATP-competitive kinase inhibitor tracer 236. Binding of the tracer is ...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM213222((S)-1-(3-((4-((Dimethylamino)methyl)-6-(thiazolo[5...)
Affinity DataIC50: 32nMAssay Description:This assay is based on the binding and displacement of Alexa-fluor 647-labeled ATP-competitive kinase inhibitor tracer 236. Binding of the tracer is ...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM213226(N-{(3S)-1-[(2E)-2-Butenoyl]-3-pyrrolidinyl}-4-{[ci...)
Affinity DataIC50: 40nMAssay Description:This assay is based on the binding and displacement of Alexa-fluor 647-labeled ATP-competitive kinase inhibitor tracer 236. Binding of the tracer is ...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM213212((trans)-4-((4-(Morpholinomethyl)-6-(thiazolo[5,4-b...)
Affinity DataIC50: 100nMAssay Description:This assay is based on the binding and displacement of Alexa-fluor 647-labeled ATP-competitive kinase inhibitor tracer 236. Binding of the tracer is ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM213219((S)-1-(3-((4-(Morpholinomethyl)-6-(thiazolo[5,4-b]...)
Affinity DataIC50: 200nMAssay Description:This assay is based on the binding and displacement of Alexa-fluor 647-labeled ATP-competitive kinase inhibitor tracer 236. Binding of the tracer is ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM213217(N-(cis-3-{[4-(4-Morpholinylmethyl)-6-([1,3]thiazol...)
Affinity DataIC50: 250nMAssay Description:This assay is based on the binding and displacement of Alexa-fluor 647-labeled ATP-competitive kinase inhibitor tracer 236. Binding of the tracer is ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM213214(N2-(1-Acryloyl-4-piperidinyl)-6-(4-morpholinylmeth...)
Affinity DataIC50: 320nMAssay Description:This assay is based on the binding and displacement of Alexa-fluor 647-labeled ATP-competitive kinase inhibitor tracer 236. Binding of the tracer is ...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM213215(N-(cis-2-{[4-(4-Morpholinylmethyl)-6-([1,3]thiazol...)
Affinity DataIC50: 320nMAssay Description:This assay is based on the binding and displacement of Alexa-fluor 647-labeled ATP-competitive kinase inhibitor tracer 236. Binding of the tracer is ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM213218(N2-[(3S)-1-Acryloyl-3-pyrrolidinyl]-6-(4-morpholin...)
Affinity DataIC50: 500nMAssay Description:This assay is based on the binding and displacement of Alexa-fluor 647-labeled ATP-competitive kinase inhibitor tracer 236. Binding of the tracer is ...More data for this Ligand-Target Pair
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PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM213213(N-(2-{[4-(4-Morpholinylmethyl)-6-([1,3]thiazolo[5,...)
Affinity DataIC50: 1.30E+3nMAssay Description:This assay is based on the binding and displacement of Alexa-fluor 647-labeled ATP-competitive kinase inhibitor tracer 236. Binding of the tracer is ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM213216(N-(trans-4-{[4-(4-Morpholinylmethyl)-6-([1,3]thiaz...)
Affinity DataIC50: 2.00E+3nMAssay Description:This assay is based on the binding and displacement of Alexa-fluor 647-labeled ATP-competitive kinase inhibitor tracer 236. Binding of the tracer is ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM213224(N2-[(3R)-1-Acryloyl-3-pyrrolidinyl]-6-(4-morpholin...)
Affinity DataIC50: 2.00E+4nMAssay Description:This assay is based on the binding and displacement of Alexa-fluor 647-labeled ATP-competitive kinase inhibitor tracer 236. Binding of the tracer is ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed