Compile Data Set for Download or QSAR
Report error Found 134 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase ABL1/ABL2'
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6096(4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50: 0.780nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6094(3-quinolinecarbonitrile 18 | 4-[(2,4-dichloro-5-me...)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6095(4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6102(4-[(2-Chloro-5-methoxyphenyl)amino]-6-methoxy-7-[(...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6099(4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50097942(3-(4-amino-7-cyclobutyl-7H-pyrrolo[2,3-d]pyrimidin...)
Affinity DataIC50: 5nMAssay Description:Inhibition of v-Abl tyrosine kinase activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6105(6-Methoxy-4-[(5-methoxy-2,4-dimethylphenyl)amino]-...)
Affinity DataIC50: 8.30nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6103(6-Methoxy-4-[(5-methoxy-2-methylphenyl)amino]-7-[(...)
Affinity DataIC50: 8.30nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50097956(3-(4-Amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidi...)
Affinity DataIC50: 10nMAssay Description:Inhibition of v-Abl tyrosine kinase activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6101(3-quinolinecarbonitrile 20 | 6-Methoxy-7-[(1-methy...)
Affinity DataIC50: 12nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6100(3-quinolinecarbonitrile 19 | 4-[(2,4-Dichloropheny...)
Affinity DataIC50: 16nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50088900(5,7-diphenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine | ...)
Affinity DataIC50: 20nMAssay Description:Tested in vitro for inhibition of non-receptor tyrosine kinase v-AblMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6104(4-[(2,4-Dimethylphenyl)amino]-6-methoxy-7-[(1-meth...)
Affinity DataIC50: 38nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM13530(cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...)
Affinity DataIC50: 40nMAssay Description:Inhibition of Abl tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50097947({3-[4-Amino-5-(3-methoxy-phenyl)-pyrrolo[2,3-d]pyr...)
Affinity DataIC50: 40nMAssay Description:Inhibition of v-Abl tyrosine kinase activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50097937(3-(4-Amino-5-phenyl-pyrrolo[2,3-d]pyrimidin-7-yl)-...)
Affinity DataIC50: 40nMAssay Description:Inhibition of v-Abl tyrosine kinase activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50088904((3-(4-amino-5-(3-methoxyphenyl)-7H-pyrrolo[2,3-d]p...)
Affinity DataIC50: 50nMAssay Description:Tested in vitro for inhibition of non-receptor tyrosine kinase v-AblMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50097945(7-cyclobutyl-5-(3-methoxyphenyl)-7H-pyrrolo[2,3-d]...)
Affinity DataIC50: 50nMAssay Description:Inhibition of v-Abl tyrosine kinase activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50097991({3-[4-Amino-5-(3-hydroxy-phenyl)-pyrrolo[2,3-d]pyr...)
Affinity DataIC50: 54nMAssay Description:Concentration required for inhibition of v-Abl receptor by tyrosine kinase enzyme assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50097971({4-[4-Amino-5-(3-hydroxy-phenyl)-pyrrolo[2,3-d]pyr...)
Affinity DataIC50: 56nMAssay Description:Concentration required for inhibition of v-Abl receptor by tyrosine kinase enzyme assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6098(4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50: 56nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50097968(3-[4-Amino-5-(3-hydroxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50: 58nMAssay Description:Concentration required for inhibition of v-Abl receptor by tyrosine kinase enzyme assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50088908(5-(3-methoxyphenyl)-7-phenyl-7H-pyrrolo[2,3-d]pyri...)
Affinity DataIC50: 60nMAssay Description:Tested in vitro for inhibition of non-receptor tyrosine kinase v-AblMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50088909([4-(4-Amino-5-phenyl-pyrrolo[2,3-d]pyrimidin-7-yl)...)
Affinity DataIC50: 70nMAssay Description:Tested in vitro for inhibition of non-receptor tyrosine kinase v-AblMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50097951(4-(4-amino-7-cyclobutyl-7H-pyrrolo[2,3-d]pyrimidin...)
Affinity DataIC50: 85nMAssay Description:Inhibition of v-Abl tyrosine kinase activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6097(4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50: 89nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50097936(7-cyclobutyl-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4...)
Affinity DataIC50: 90nMAssay Description:Inhibition of v-Abl tyrosine kinase activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50097967(3-(4-amino-7-(1-(2-hydroxyethyl)piperidin-4-yl)-7H...)
Affinity DataIC50: 98nMAssay Description:Concentration required for inhibition of v-Abl receptor by tyrosine kinase enzyme assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 100nMAssay Description:Inhibition of Abl tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50097941(4-(4-amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidi...)
Affinity DataIC50: 110nMAssay Description:Inhibition of v-Abl tyrosine kinase activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50097958(2-{4-[4-Amino-5-(3-hydroxy-phenyl)-pyrrolo[2,3-d]p...)
Affinity DataIC50: 120nMAssay Description:Concentration required for inhibition of v-Abl receptor by tyrosine kinase enzyme assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM3532(CHEMBL7917 | CHEMBL540068 | N-(3-chlorophenyl)-6,7...)
Affinity DataIC50: 125nMAssay Description:Inhibition of v-Abl tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50097955(7-cyclopentyl-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-...)
Affinity DataIC50: 140nMAssay Description:Inhibition of v-Abl tyrosine kinase activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50097962(2-{3-[4-Amino-5-(3-hydroxy-phenyl)-pyrrolo[2,3-d]p...)
Affinity DataIC50: 150nMAssay Description:Concentration required for inhibition of v-Abl receptor by tyrosine kinase enzyme assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50097939(7-Cyclopentyl-5-(3-methoxy-phenyl)-7H-pyrrolo[2,3-...)
Affinity DataIC50: 170nMAssay Description:Inhibition of v-Abl tyrosine kinase activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50132707(4-3,3-dimethyltriaz-1-ene-N-[4-methyl-3-(4-pyridin...)
Affinity DataIC50: 195nMAssay Description:Inhibition of Abl tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50088902((3-(4-amino-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-7-...)
Affinity DataIC50: 200nMAssay Description:Tested in vitro for inhibition of non-receptor tyrosine kinase v-AblMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50097979(2-{4-[4-Amino-5-(3-hydroxy-phenyl)-pyrrolo[2,3-d]p...)
Affinity DataIC50: 210nMAssay Description:Concentration required for inhibition of v-Abl receptor by tyrosine kinase enzyme assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50088898(2-(4-(4-amino-5-(3-methoxyphenyl)-7H-pyrrolo[2,3-d...)
Affinity DataIC50: 220nMAssay Description:Tested in vitro for inhibition of non-receptor tyrosine kinase v-AblMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50088899(2-(4-(4-amino-5-(3-methoxyphenyl)-7H-pyrrolo[2,3-d...)
Affinity DataIC50: 230nMAssay Description:Tested in vitro for inhibition of non-receptor tyrosine kinase v-AblMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50097944(3-[4-Amino-5-(3-methoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50: 230nMAssay Description:Inhibition of v-Abl tyrosine kinase activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50097954(7-Cyclopentyl-5-(4-methoxy-phenyl)-7H-pyrrolo[2,3-...)
Affinity DataIC50: 260nMAssay Description:Inhibition of v-Abl tyrosine kinase activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50097959(7-{1-[2-(2-Methoxy-ethylamino)-ethyl]-piperidin-4-...)
Affinity DataIC50: 260nMAssay Description:Inhibition of v-Abl receptor tyrosine kinase enzyme activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50097972(3-(4-Amino-7-pyrrolidin-3-yl-7H-pyrrolo[2,3-d]pyri...)
Affinity DataIC50: 290nMAssay Description:Concentration required for inhibition of v-Abl receptor by tyrosine kinase enzyme assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50088903(2-((4-(4-amino-5-(3-methoxyphenyl)-7H-pyrrolo[2,3-...)
Affinity DataIC50: 300nMAssay Description:Tested in vitro for inhibition of non-receptor tyrosine kinase v-AblMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50097946(3-{4-Amino-7-[1-hydroxymethyl-2-(4-methoxy-phenyl)...)
Affinity DataIC50: 340nMAssay Description:Inhibition of v-Abl tyrosine kinase activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50097974(2-((2-(4-(4-amino-5-(3-methoxyphenyl)-7H-pyrrolo[2...)
Affinity DataIC50: 360nMAssay Description:Concentration required for inhibition of v-Abl receptor by tyrosine kinase enzyme assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50097938(3-(4-Amino-5-phenyl-pyrrolo[2,3-d]pyrimidin-7-yl)-...)
Affinity DataIC50: 390nMAssay Description:Inhibition of v-Abl tyrosine kinase activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50088913(5-(4-Methoxy-phenyl)-7-phenyl-7H-pyrrolo[2,3-d]pyr...)
Affinity DataIC50: 400nMAssay Description:Tested in vitro for inhibition of non-receptor tyrosine kinase v-AblMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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