Compile Data Set for Download or QSAR
Report error Found 262 Enz. Inhib. hit(s) with Target = 'Tubulin beta-2B chain'
TargetTubulin beta-2B chain(Bovine)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50107672((3-Fluoro-phenyl)-(5-methoxy-1H-indol-2-yl)-methan...)
Affinity DataIC50: 390nMAssay Description:Inhibition of tubulin polymerization.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTubulin beta-2B chain(Bovine)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50035218(podophyllotoxin | CHEMBL61 | Podophyllinic acid la...)
Affinity DataIC50: 460nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTubulin beta-2B chain(Bovine)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50035218(podophyllotoxin | CHEMBL61 | Podophyllinic acid la...)
Affinity DataIC50: 460nMAssay Description:Inhibition of bovine tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTubulin beta-2B chain(Bovine)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50005480(combretastin A4 | CHEMBL67 | 2-Methoxy-5-[2-(3,4,5...)
Affinity DataIC50: 530nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTubulin beta-2B chain(Bovine)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50005480(combretastin A4 | CHEMBL67 | 2-Methoxy-5-[2-(3,4,5...)
Affinity DataIC50: 530nMAssay Description:Inhibition of bovine tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTubulin beta-2B chain(Bovine)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50107678((5-Methoxy-1H-indol-2-yl)-(3-methoxy-phenyl)-metha...)
Affinity DataIC50: 530nMAssay Description:Inhibition of tubulin polymerization.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTubulin beta-2B chain(Bovine)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50107658((5-methoxy-1H-indol-2-yl)(phenyl)methanone | (5-Me...)
Affinity DataIC50: 530nMAssay Description:Inhibition of tubulin polymerization.More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetTubulin beta-2B chain(Bovine)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50037444(6-(3-Methoxy-phenyl)-5H-[1,3]dioxolo[4,5-g]quinoli...)
Affinity DataIC50: 570nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTubulin beta-2B chain(Bovine)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50041130(6-Methoxy-2-phenyl-1H-quinolin-4-one | GNF-PF-117 ...)
Affinity DataIC50: 610nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTubulin beta-2B chain(Bovine)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50041123(6-(3,5-Dimethoxy-phenyl)-5H-[1,3]dioxolo[4,5-g]qui...)
Affinity DataIC50: 620nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTubulin beta-2B chain(Bovine)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50059123(2-(3-Methoxy-phenyl)-5-methyl-1H-[1,8]naphthyridin...)
Affinity DataIC50: 620nMAssay Description:Inhibition of bovine tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTubulin beta-2B chain(Bovine)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50037464(6-Phenyl-5H-[1,3]dioxolo[4,5-g]quinolin-8-one | CH...)
Affinity DataIC50: 630nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTubulin beta-2B chain(Bovine)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50005478(CHEMBL10557 | 2-methoxy-5-(3,4,5-trimethoxypheneth...)
Affinity DataIC50: 630nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetTubulin beta-2B chain(Bovine)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50107677((3-Hydroxy-phenyl)-(5-methoxy-1H-indol-2-yl)-metha...)
Affinity DataIC50: 660nMAssay Description:Inhibition of tubulin polymerization.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTubulin beta-2B chain(Bovine)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50111568(2-Methoxy-5-[5-(3,4,5-trimethoxy-phenyl)-3H-imidaz...)
Affinity DataIC50: 680nMAssay Description:Concentration needed to inhibit tubulin polymerization by 50%More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTubulin beta-2B chain(Bovine)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50037452(6-(3-Dimethylamino-phenyl)-5H-[1,3]dioxolo[4,5-g]q...)
Affinity DataIC50: 700nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTubulin beta-2B chain(Bovine)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50059100(6-Chloro-2-(3-methoxy-phenyl)-1H-[1,8]naphthyridin...)
Affinity DataIC50: 730nMAssay Description:Inhibition of bovine tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTubulin beta-2B chain(Bovine)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50111579(2-Methoxy-5-[5-(3,4,5-trimethoxy-phenyl)-3H-imidaz...)
Affinity DataIC50: 730nMAssay Description:Concentration needed to inhibit tubulin polymerization by 50%More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTubulin beta-2B chain(Bovine)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50041100(6-Methoxy-2-(3-methoxy-phenyl)-1H-quinolin-4-one |...)
Affinity DataIC50: 740nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTubulin beta-2B chain(Bovine)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50059117(2-(3-Methoxy-phenyl)-7-methyl-1H-[1,8]naphthyridin...)
Affinity DataIC50: 750nMAssay Description:Inhibition of bovine tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTubulin beta-2B chain(Bovine)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50111574(1-Methyl-5-[4-(3,4,5-trimethoxy-phenyl)-oxazol-5-y...)
Affinity DataIC50: 790nMAssay Description:Concentration needed to inhibit tubulin polymerization by 50%More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTubulin beta-2B chain(Bovine)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50014846(7alphaH-colchicine | (S)-N-(5,6,7,9-tetrahydro-1,2...)
Affinity DataIC50: 800nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTubulin beta-2B chain(Bovine)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50014846(7alphaH-colchicine | (S)-N-(5,6,7,9-tetrahydro-1,2...)
Affinity DataIC50: 800nMAssay Description:Inhibition of bovine tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTubulin beta-2B chain(Bovine)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50059111(2-(3-Methoxy-phenyl)-6-methyl-1H-[1,8]naphthyridin...)
Affinity DataIC50: 800nMAssay Description:Inhibition of bovine tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTubulin beta-2B chain(Bovine)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50107656((3,5-Dimethoxy-phenyl)-(5-methoxy-1H-indol-2-yl)-m...)
Affinity DataIC50: 810nMAssay Description:Inhibition of tubulin polymerization.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTubulin beta-2B chain(Bovine)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50107676((3,4-Dimethoxy-phenyl)-(5-methoxy-1H-indol-2-yl)-m...)
Affinity DataIC50: 810nMAssay Description:Inhibition of tubulin polymerization.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTubulin beta-2B chain(Bovine)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50041121(2-(3-Dimethylamino-phenyl)-6-methoxy-1H-quinolin-4...)
Affinity DataIC50: 840nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTubulin beta-2B chain(Bovine)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50041119(2-(2-fluorophenyl)-6,7-methylenedioxyquinolin-4-on...)
Affinity DataIC50: 850nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTubulin beta-2B chain(Bovine)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50107674(Butyric acid 3-(5-methoxy-1H-indole-2-carbonyl)-ph...)
Affinity DataIC50: 850nMAssay Description:Inhibition of tubulin polymerization.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTubulin beta-2B chain(Bovine)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50107664((5-Methoxy-1H-indol-2-yl)-(3-nitro-phenyl)-methano...)
Affinity DataIC50: 850nMAssay Description:Inhibition of tubulin polymerization.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTubulin beta-2B chain(Bovine)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50107693((5-Methyl-1H-indol-2-yl)-(3,4,5-trimethoxy-phenyl)...)
Affinity DataIC50: 860nMAssay Description:Inhibition of tubulin polymerization.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTubulin beta-2B chain(Bovine)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50111554(Dimethyl-{4-[4-(3,4,5-trimethoxy-phenyl)-oxazol-5-...)
Affinity DataIC50: 870nMAssay Description:Concentration needed to inhibit tubulin polymerization by 50%More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTubulin beta-2B chain(Bovine)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50059103(2-(3-Methoxy-phenyl)-5,7-dimethyl-1H-[1,8]naphthyr...)
Affinity DataIC50: 880nMAssay Description:Inhibition of bovine tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTubulin beta-2B chain(Bovine)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50041106(6-(2-Chloro-phenyl)-5H-[1,3]dioxolo[4,5-g]quinolin...)
Affinity DataIC50: 890nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTubulin beta-2B chain(Bovine)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50369013(CHEMBL1627442)
Affinity DataIC50: 910nMAssay Description:In vitro inhibition of tubulin polymerization.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTubulin beta-2B chain(Bovine)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50111558(2-Methoxy-5-[4-(3,4,5-trimethoxy-phenyl)-oxazol-5-...)
Affinity DataIC50: 920nMAssay Description:Concentration needed to inhibit tubulin polymerization by 50%More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTubulin beta-2B chain(Bovine)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50059122(2-(3-Methoxy-phenyl)-1H-[1,8]naphthyridin-4-one | ...)
Affinity DataIC50: 960nMAssay Description:Inhibition of bovine tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTubulin beta-2B chain(Bovine)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50111567(2-Methoxy-5-[4-(3,4,5-trimethoxy-phenyl)-oxazol-5-...)
Affinity DataIC50: 980nMAssay Description:Concentration needed to inhibit tubulin polymerization by 50%More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTubulin beta-2B chain(Bovine)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50107662((3-Amino-phenyl)-(5-methoxy-1H-indol-2-yl)-methano...)
Affinity DataIC50: 990nMAssay Description:Inhibition of tubulin polymerization.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTubulin beta-2B chain(Bovine)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50107651((5-Methoxy-1H-indol-2-yl)-(3,4,5-trimethoxy-phenyl...)
Affinity DataIC50: 990nMAssay Description:Inhibition of tubulin polymerization.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTubulin beta-2B chain(Bovine)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50041115(6-p-Tolyl-5H-[1,3]dioxolo[4,5-g]quinolin-8-one | C...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTubulin beta-2B chain(Bovine)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50107663((2-Fluoro-phenyl)-(5-methoxy-1H-indol-2-yl)-methan...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of tubulin polymerization.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTubulin beta-2B chain(Bovine)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50041103(6-Benzo[1,3]dioxol-5-yl-5H-[1,3]dioxolo[4,5-g]quin...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTubulin beta-2B chain(Bovine)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50111566(1-Methyl-6-[5-(3,4,5-trimethoxy-phenyl)-3H-imidazo...)
Affinity DataIC50: 1.10E+3nMAssay Description:Concentration needed to inhibit tubulin polymerization by 50%More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTubulin beta-2B chain(Bovine)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50005480(combretastin A4 | CHEMBL67 | 2-Methoxy-5-[2-(3,4,5...)
Affinity DataIC50: 1.20E+3nMAssay Description:Concentration needed to inhibit tubulin polymerization by 50%More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTubulin beta-2B chain(Bovine)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50107670((5-Methoxy-1H-indol-2-yl)-(2-methoxy-phenyl)-metha...)
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of tubulin polymerization.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTubulin beta-2B chain(Bovine)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50041109(6-(1H-Indol-3-yl)-5H-[1,3]dioxolo[4,5-g]quinolin-8...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTubulin beta-2B chain(Bovine)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50035218(podophyllotoxin | CHEMBL61 | Podophyllinic acid la...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTubulin beta-2B chain(Bovine)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50014845(CHEMBL351349 | Carbonic acid 7-acetylamino-1,2-dim...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibitory effect on the polymerization of purified bovine brain tubulin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTubulin beta-2B chain(Bovine)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50014855(CHEMBL19531 | 1,2,3-Trimethoxy-7-methylamino-10-me...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibitory effect on the polymerization of purified bovine brain tubulin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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