Report error Found 8 Enz. Inhib. hit(s) with Target = 'Trypanothione synthetase'
Affinity DataIC50: 30nMAssay Description:Inhibition of Crithidia fasciculata His tagged TryS in presence of ATP by LDH/PK assayMore data for this Ligand-Target Pair
TargetTrypanothione synthetase(Trypanosoma cruzi (strain CL Brener))
National Institute of Advanced Industrial Science and Technology (Aist)
Curated by ChEMBL
National Institute of Advanced Industrial Science and Technology (Aist)
Curated by ChEMBL
Affinity DataIC50: 93nMAssay Description:Inhibition of Trypanosoma cruzi strain CL Brener N-terminal poly-His tagged spermidine synthase expressed in Escherichia coli BL21(DE3) using 50 uM p...More data for this Ligand-Target Pair
TargetTrypanothione synthetase(Trypanosoma cruzi (strain CL Brener))
National Institute of Advanced Industrial Science and Technology (Aist)
Curated by ChEMBL
National Institute of Advanced Industrial Science and Technology (Aist)
Curated by ChEMBL
Affinity DataIC50: 95nMpH: 8.0 T: 2°CAssay Description:Hit compounds identified from the high throughput screen were also tested using orthogonal assay platform, namely the coupled assay described previou...More data for this Ligand-Target Pair
TargetTrypanothione synthetase(Trypanosoma cruzi (strain CL Brener))
National Institute of Advanced Industrial Science and Technology (Aist)
Curated by ChEMBL
National Institute of Advanced Industrial Science and Technology (Aist)
Curated by ChEMBL
Affinity DataIC50: 140nMpH: 8.0 T: 2°CAssay Description:Hit compounds identified from the high throughput screen were also tested using orthogonal assay platform, namely the coupled assay described previou...More data for this Ligand-Target Pair
TargetTrypanothione synthetase(Trypanosoma cruzi (strain CL Brener))
National Institute of Advanced Industrial Science and Technology (Aist)
Curated by ChEMBL
National Institute of Advanced Industrial Science and Technology (Aist)
Curated by ChEMBL
Affinity DataIC50: 273nMpH: 8.0 T: 2°CAssay Description:Hit compounds identified from the high throughput screen were also tested using orthogonal assay platform, namely the coupled assay described previou...More data for this Ligand-Target Pair
TargetTrypanothione synthetase(Trypanosoma cruzi (strain CL Brener))
National Institute of Advanced Industrial Science and Technology (Aist)
Curated by ChEMBL
National Institute of Advanced Industrial Science and Technology (Aist)
Curated by ChEMBL
Affinity DataIC50: 317nMpH: 8.0 T: 2°CAssay Description:Hit compounds identified from the high throughput screen were also tested using orthogonal assay platform, namely the coupled assay described previou...More data for this Ligand-Target Pair
TargetTrypanothione synthetase(Trypanosoma cruzi (strain CL Brener))
National Institute of Advanced Industrial Science and Technology (Aist)
Curated by ChEMBL
National Institute of Advanced Industrial Science and Technology (Aist)
Curated by ChEMBL
Affinity DataIC50: 620nMAssay Description:Inhibition of Trypanosoma cruzi strain CL Brener N-terminal poly-His tagged spermidine synthase expressed in Escherichia coli BL21(DE3) using 0.5 mM ...More data for this Ligand-Target Pair
TargetTrypanothione synthetase(Trypanosoma cruzi (strain CL Brener))
National Institute of Advanced Industrial Science and Technology (Aist)
Curated by ChEMBL
National Institute of Advanced Industrial Science and Technology (Aist)
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Trypanosoma cruzi strain CL Brener N-terminal poly-His tagged spermidine synthase expressed in Escherichia coli BL21(DE3) using 50 uM p...More data for this Ligand-Target Pair
