Compile Data Set for Download or QSAR
Report error Found 1911 Enz. Inhib. hit(s) with Target = 'Translocator protein' Sort by
TargetTranslocator protein(Rat)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM22040(Ro5-4864 | 4' Cl-diazepam | 4 -chlorodiazepam ...)
Affinity DataKd:  3.5nMAssay Description:Binding affinity constant for Benzodiazepine receptor in rat RG-2 glioma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM22040(Ro5-4864 | 4' Cl-diazepam | 4 -chlorodiazepam ...)
Affinity DataKd:  4.00E+3nMAssay Description:Binding affinity constant for Benzodiazepine receptor in rat C6 glioma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM22040(Ro5-4864 | 4' Cl-diazepam | 4 -chlorodiazepam ...)
Affinity DataKd:  1.30E+3nMAssay Description:Binding affinity constant for Benzodiazepine receptor in normal rat brain homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50316600(N,N-Dipropyl-[5-isothiocyanato-2-phenylindol-3-yl)...)
Affinity DataKd:  3.17nMAssay Description:Irreversible binding affinity to TSPO in rat kidney mitochondrial membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50316601(N,N-Dihexyl-[5-isothiocyanato-2-phenylindol-3-yl)g...)
Affinity DataKd:  5.07nMAssay Description:Irreversible binding affinity to TSPO in rat kidney mitochondrial membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50316602(N-(5-Isothiocyanato-2-phenylindol-3-ylglyoxyl)-N'-...)
Affinity DataKd:  8.31nMAssay Description:Irreversible binding affinity to TSPO in rat kidney mitochondrial membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50000766(CHEMBL12 | DIAZEPAM | US9271961, Diazepam)
Affinity DataKd:  213nMAssay Description:Binding affinity constant for peripheral (mitochondrial) Benzodiazepine receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM22032(PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...)
Affinity DataKd:  2nMAssay Description:Binding affinity constant for peripheral (mitochondrial) Benzodiazepine receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTranslocator protein(Rat)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50021058(7-Chloro-1-methyl-5-phenyl-2,3-dihydro-1H-benzo[e]...)
Affinity DataKd: >10nMAssay Description:Binding affinity constant for peripheral (mitochondrial) Benzodiazepine receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM22040(Ro5-4864 | 4' Cl-diazepam | 4 -chlorodiazepam ...)
Affinity DataKd:  58nMAssay Description:Binding affinity constant for peripheral (mitochondrial) Benzodiazepine receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM22040(Ro5-4864 | 4' Cl-diazepam | 4 -chlorodiazepam ...)
Affinity DataKd:  6nMAssay Description:Binding affinity to human PBRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50255226(SR-180575 | (7-chloro-N,N,5-trimethyl-4-oxo-3-phen...)
Affinity DataKd:  3.5nMAssay Description:Binding affinity to human PBRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50045877(2-(2-(4-fluorophenyl)-1H-indol-3-yl)-N,N-dihexylac...)
Affinity DataKd:  4nMAssay Description:Binding affinity to human PBRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM22032(PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...)
Affinity DataKd:  2nMAssay Description:Binding affinity to human PBRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM22040(Ro5-4864 | 4' Cl-diazepam | 4 -chlorodiazepam ...)
Affinity DataKd:  1.10nMAssay Description:Displacement of [3H]Ro5-4864 from TSPO in rat kainate lesioned striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM22032(PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...)
Affinity DataKd:  0.600nMAssay Description:Displacement of [3H]PK11195 from TSPO in rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTranslocator protein(Rat)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50255226(SR-180575 | (7-chloro-N,N,5-trimethyl-4-oxo-3-phen...)
Affinity DataKd:  3nMAssay Description:Displacement of [3H]SSR180575 from TSPO in rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50336914(3-[(21S,22S)-16-ethenyl-11-ethyl-12,17,21,26-tetra...)
Affinity DataKd:  40nMAssay Description:Binding affinity to PBRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM22032(PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...)
Affinity DataKd:  11nMAssay Description:Binding affinity to recombinant human TSPO by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2018
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50210940(CHEMBL3948914)
Affinity DataKd:  108nMAssay Description:Binding affinity to recombinant human TSPO by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2018
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50279019(CHEMBL1315992)
Affinity DataKd:  40nMAssay Description:Binding affinity to C-terminal DDK-tagged human recombinant full-length TSPO expressed in HEK293 cells by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM22032(PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...)
Affinity DataKd:  11nMAssay Description:Binding affinity to C-terminal DDK-tagged human recombinant full-length TSPO expressed in HEK293 cells by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50279015(CHEMBL4174207)
Affinity DataKd:  61nMAssay Description:Binding affinity to C-terminal DDK-tagged human recombinant full-length TSPO expressed in HEK293 cells by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50588818(CHEMBL5174807)
Affinity DataEC50:  3.90E+4nMAssay Description:Inhibition of TSPO (unknown origin) in mouse MA-10 cells assessed as increase in steroid steroidogenesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50274258(2-(6,8-Dichloro-2-(4-methoxyphenyl)imidazo[1,2-a]p...)
Affinity DataEC50:  571nMAssay Description:Inhibition of TSPO (unknown origin) in mouse MA-10 cells assessed as increase in steroid steroidogenesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50588816(CHEMBL5191240)
Affinity DataEC50:  6.99E+3nMAssay Description:Inhibition of TSPO (unknown origin) in mouse MA-10 cells assessed as increase in steroid steroidogenesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50060095(2-[6,8-Dichloro-2-(4-chloro-phenyl)-imidazo[1,2-a]...)
Affinity DataEC50:  337nMAssay Description:Inhibition of TSPO (unknown origin) in mouse MA-10 cells assessed as increase in steroid steroidogenesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50588817(CHEMBL5193551)
Affinity DataEC50:  1.59E+4nMAssay Description:Inhibition of TSPO (unknown origin) in mouse MA-10 cells assessed as increase in steroid steroidogenesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50588819(CHEMBL5194870)
Affinity DataEC50:  2.12E+4nMAssay Description:Inhibition of TSPO (unknown origin) in mouse MA-10 cells assessed as increase in steroid steroidogenesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM22040(Ro5-4864 | 4' Cl-diazepam | 4 -chlorodiazepam ...)
Affinity DataKd:  1.10nMAssay Description:Binding affinity to TSPO receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50378901(CHEMBL1672418)
Affinity DataKd:  10nMAssay Description:Binding affinity to human TSPOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50054139((R)1-(2-Chloro-phenyl)-isoquinoline-3-carboxylic a...)
Affinity DataKd:  2nMAssay Description:Binding affinity to human TSPOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTranslocator protein(Rat)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50409615(CHEMBL5282701)
Affinity DataKd:  3.80nMAssay Description:Displacement of [3H]PK11195 from TSPO receptor in rat brain cortex mitochondrial membrane incubated for 60 mins by liquid scintillation spectrometer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTranslocator protein(Rat)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50355784(CHEMBL1911623)
Affinity DataIC50: 0.130nMAssay Description:Displacement of [3H]PK11195 from TSPO in Sprague-Dawley rat brain homogenates after 90 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50355785(CHEMBL1911624)
Affinity DataIC50: 0.130nMAssay Description:Displacement of [3H]PK11195 from TSPO in Sprague-Dawley rat brain homogenates after 90 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50355781(CHEMBL1911620)
Affinity DataIC50: 0.140nMAssay Description:Displacement of [3H]PK11195 from TSPO in Sprague-Dawley rat brain homogenates after 90 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50355786(CHEMBL1911625)
Affinity DataIC50: 0.280nMAssay Description:Displacement of [3H]PK11195 from TSPO in Sprague-Dawley rat brain homogenates after 90 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50271820(1-(2-iodophenyl)-N-methyl-N-(3-fluoropropyl)-3-iso...)
Affinity DataIC50: 0.280nMAssay Description:Displacement of [3H]PK11195 from PBR in rat kidney mitochondrial membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50122293(CHEMBL63064 | N-(2,5-Dimethoxy-benzyl)-N-(5-fluoro...)
Affinity DataIC50: 0.280nMAssay Description:Inhibition of TSPO receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTranslocator protein(Rat)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50355783(CHEMBL1911622)
Affinity DataIC50: 0.340nMAssay Description:Displacement of [3H]PK11195 from TSPO in Sprague-Dawley rat brain homogenates after 90 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50131724(3-Chloromethyl-4-phenyl-quinoline-2-carboxylic aci...)
Affinity DataIC50: 0.450nMAssay Description:Inhibitory activity against specific binding of [3H]-CB 34 to peripheral benzodiazepine receptor in rat cortical membranes was evaluatedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM22041(2-[6-chloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridi...)
Affinity DataIC50: 0.5nMAssay Description:Displacement of [3H]PK11195 from TSPO receptor in rat brain cortex membrane incubated for 120 mins by liquid scintillation spectrometer methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTranslocator protein(Rat)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50054126((E)-N-(4-chlorophenyl)-2-(2-(4-chlorophenyl)-1-oxo...)
Affinity DataIC50: 0.620nMAssay Description:Displacement of [3H]PK115 from peripheral benzodiazepine receptor in Sprague-Dawley rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50052754(Diethyl-carbamic acid 5-phenyl-6-oxa-10b-aza-benzo...)
Affinity DataIC50: 0.680nMAssay Description:Inhibition of binding of [3H]-PK 11195 to peripheral-type benzodiazepine receptor (PBR) from rat cortex homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50054125(2-[2-(4-Chloro-phenyl)-1-oxo-1,2-dihydro-pyrrolo[3...)
Affinity DataIC50: 0.700nMAssay Description:Displacement of [3H]PK11195 from rat kidney peripheral benzodiazepine receptor (type 1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50122294(N-(5-fluoro-2-phenoxyphenyl)-N-(2-(2-fluoroethoxy)...)
Affinity DataIC50: 0.770nMAssay Description:In vitro binding affinity for PBR (peripheral benzodiazepine receptor) in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50060126(2-[6,8-Dibromo-2-(4-chloro-phenyl)-imidazo[1,2-a]p...)
Affinity DataIC50: 0.794nMAssay Description:Displacement of [3H]-PK 11195 from peripheral-type benzodiazepine receptor of rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50355782(CHEMBL1911621)
Affinity DataIC50: 0.830nMAssay Description:Displacement of [3H]PK11195 from TSPO in Sprague-Dawley rat brain homogenates after 90 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50054125(2-[2-(4-Chloro-phenyl)-1-oxo-1,2-dihydro-pyrrolo[3...)
Affinity DataIC50: 0.900nMAssay Description:Displacement of [3H]PK115 from peripheral benzodiazepine receptor in Sprague-Dawley rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50185957(N-(4-chloro-2-phenoxyphenyl)-N-(2-isopropoxybenzyl...)
Affinity DataIC50: 0.920nMAssay Description:Inhibition of TSPO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2018
Entry Details Article
PubMed
Displayed 1 to 50 (of 1911 total ) | Next | Last >>
Jump to: