Compile Data Set for Download or QSAR
Report error Found 91 Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily V member 6'
LigandPNGBDBM50459973(Sor-c13)
Affinity DataIC50: 14nMAssay Description:Inhibition of TRPV6 (unknown origin) expressed in HEK293 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50502759(CHEMBL4435596)
Affinity DataIC50: 50nMAssay Description:Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction in Cd2+ influx by calcium-5 fluorescence dye-based FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50550080(CHEMBL4796516)
Affinity DataIC50: 64nMAssay Description:Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction in Cd2+ influx by calcium-5 fluorescence dye-based FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50550078(CHEMBL4777551)
Affinity DataIC50: 82nMAssay Description:Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction in Cd2+ influx by calcium-5 fluorescence dye-based FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50550077(CHEMBL4789936)
Affinity DataIC50: 130nMAssay Description:Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction in Cd2+ influx by calcium-5 fluorescence dye-based FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50550081(CHEMBL4740003)
Affinity DataIC50: 150nMAssay Description:Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction in Cd2+ influx by calcium-5 fluorescence dye-based FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50550082(CHEMBL4760109)
Affinity DataIC50: 170nMAssay Description:Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction in Cd2+ influx by calcium-5 fluorescence dye-based FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50502759(CHEMBL4435596)
Affinity DataIC50: 320nMAssay Description:Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction of Cd2+ influx preincubated for 5 mins followed by CdCl2 addition by calciu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50550085(CHEMBL4762249)
Affinity DataIC50: 370nMAssay Description:Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction in Cd2+ influx by calcium-5 fluorescence dye-based FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50550087(CHEMBL4761058)
Affinity DataIC50: 430nMAssay Description:Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction in Cd2+ influx by calcium-5 fluorescence dye-based FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50550083(CHEMBL4746237)
Affinity DataIC50: 550nMAssay Description:Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction in Cd2+ influx by calcium-5 fluorescence dye-based FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50502760(CHEMBL4475503)
Affinity DataIC50: 550nMAssay Description:Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction in Cd2+ influx by calcium-5 fluorescence dye-based FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50550084(CHEMBL4789446)
Affinity DataIC50: 600nMAssay Description:Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction in Cd2+ influx by calcium-5 fluorescence dye-based FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50502757(CHEMBL4470714)
Affinity DataIC50: 600nMAssay Description:Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction in Cd2+ influx preincubated for 5 mins followed by CdCl2 addition using 365...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50502761(CHEMBL4448267)
Affinity DataIC50: 600nMAssay Description:Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction of Cd2+ influx preincubated for 5 mins followed by CdCl2 addition measured ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50550079(CHEMBL4742895)
Affinity DataIC50: 690nMAssay Description:Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction in Cd2+ influx by calcium-5 fluorescence dye-based FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50550089(CHEMBL4789968)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction in Cd2+ influx by calcium-5 fluorescence dye-based FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50502760(CHEMBL4475503)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction of Cd2+ influx preincubated for 5 mins followed by CdCl2 addition by calciu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50502762(CHEMBL4579017)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction in Cd2+ influx preincubated for 5 mins followed by CdCl2 addition using 365...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50550088(CHEMBL4792477)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction in Cd2+ influx by calcium-5 fluorescence dye-based FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50550086(CHEMBL4790237)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction in Cd2+ influx by calcium-5 fluorescence dye-based FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50550090(CHEMBL4749205)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction in Cd2+ influx by calcium-5 fluorescence dye-based FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50434536(CHEMBL2386186)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of human TRPV6 transfected in HEK293 cells assessed as inhibition of Cd2+ influx after 5 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50434536(CHEMBL2386186)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of human TRPV6 transfected in HEK293 cells assessed as inhibition of Ca2+ influx after 5 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50511105(GWP-42004 | Gwp42004 | O-4394 | THCV | Tetrahydroc...)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of TRPV6 channel (unknown origin) by Patch-clamp assayMore data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50434538(CHEMBL2386184)
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of human TRPV6 transfected in HEK293 cells assessed as inhibition of Ca2+ influx after 5 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50434537(CHEMBL2386185)
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of human TRPV6 transfected in HEK293 cells assessed as inhibition of Cd2+ influx after 5 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50434539(CHEMBL2386183)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human TRPV6 transfected in HEK293 cells assessed as inhibition of Cd2+ influx after 5 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50502758(CHEMBL4580679)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction of Cd2+ influx preincubated for 5 mins followed by CdCl2 addition measured ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50434550(CHEMBL2386171)
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibition of human TRPV6 transfected in HEK293 cells assessed as inhibition of Ca2+ influx after 5 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50434550(CHEMBL2386171)
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of human TRPV6 transfected in HEK293 cells assessed as inhibition of Cd2+ influx after 5 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50434535(CHEMBL2386187)
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of human TRPV6 transfected in HEK293 cells assessed as inhibition of Ca2+ influx after 5 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50434538(CHEMBL2386184)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human TRPV6 transfected in HEK293 cells assessed as inhibition of Cd2+ influx after 5 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50434541(CHEMBL2386180)
Affinity DataIC50: 1.21E+4nMAssay Description:Inhibition of human TRPV6 transfected in HEK293 cells assessed as inhibition of Cd2+ influx after 5 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50434539(CHEMBL2386183)
Affinity DataIC50: 1.23E+4nMAssay Description:Inhibition of human TRPV6 transfected in HEK293 cells assessed as inhibition of Ca2+ influx after 5 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50434535(CHEMBL2386187)
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of human TRPV6 transfected in HEK293 cells assessed as inhibition of Cd2+ influx after 5 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50434542(CHEMBL2386179)
Affinity DataIC50: 1.29E+4nMAssay Description:Inhibition of human TRPV6 transfected in HEK293 cells assessed as inhibition of Cd2+ influx after 5 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50434558(CHEMBL2386003)
Affinity DataIC50: 1.29E+4nMAssay Description:Inhibition of human TRPV6 transfected in HEK293 cells assessed as inhibition of Ca2+ influx after 5 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50434537(CHEMBL2386185)
Affinity DataIC50: 1.32E+4nMAssay Description:Inhibition of human TRPV6 transfected in HEK293 cells assessed as inhibition of Ca2+ influx after 5 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50434549(CHEMBL2386172)
Affinity DataIC50: 1.37E+4nMAssay Description:Inhibition of human TRPV6 transfected in HEK293 cells assessed as inhibition of Cd2+ influx after 5 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50434547(CHEMBL2386174)
Affinity DataIC50: 1.42E+4nMAssay Description:Inhibition of human TRPV6 transfected in HEK293 cells assessed as inhibition of Cd2+ influx after 5 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50434541(CHEMBL2386180)
Affinity DataIC50: 1.43E+4nMAssay Description:Inhibition of human TRPV6 transfected in HEK293 cells assessed as inhibition of Ca2+ influx after 5 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50434553(CHEMBL2386009)
Affinity DataIC50: 1.44E+4nMAssay Description:Inhibition of human TRPV6 transfected in HEK293 cells assessed as inhibition of Ca2+ influx after 5 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50434560(CHEMBL2386000)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human TRPV6 transfected in HEK293 cells assessed as inhibition of Ca2+ influx after 5 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50434561(CHEMBL2385999)
Affinity DataIC50: 1.62E+4nMAssay Description:Inhibition of human TRPV6 transfected in HEK293 cells assessed as inhibition of Ca2+ influx after 5 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50434549(CHEMBL2386172)
Affinity DataIC50: 1.63E+4nMAssay Description:Inhibition of human TRPV6 transfected in HEK293 cells assessed as inhibition of Ca2+ influx after 5 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50434547(CHEMBL2386174)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human TRPV6 transfected in HEK293 cells assessed as inhibition of Ca2+ influx after 5 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50434553(CHEMBL2386009)
Affinity DataIC50: 1.71E+4nMAssay Description:Inhibition of human TRPV6 transfected in HEK293 cells assessed as inhibition of Cd2+ influx after 5 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50434534(CHEMBL2386188)
Affinity DataIC50: 1.77E+4nMAssay Description:Inhibition of human TRPV6 transfected in HEK293 cells assessed as inhibition of Cd2+ influx after 5 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50434562(CHEMBL2385998)
Affinity DataIC50: 1.85E+4nMAssay Description:Inhibition of human TRPV6 transfected in HEK293 cells assessed as inhibition of Ca2+ influx after 5 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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