Report error Found 197 Enz. Inhib. hit(s) with Target = 'Transcription intermediary factor 1-alpha'
Displayed 1 to 50 (of 197 total ) | Next | Last >>
TargetTranscription intermediary factor 1-alpha(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataKd: <1nMAssay Description:Binding affinity to human partial length TRIM24 phd bromodomain (P790 to P977 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataKd: <1nMAssay Description:Binding affinity to human partial length TRIM24 (G862 to E980 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataKd: 1.30nMAssay Description:Binding affinity to recombinant human TRIM24-PHD/bromodomain expressed in bacterial system by bromoscan assayMore data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 7.60nMAssay Description:Inhibition of recombinant human His-tagged TRIM24-PHD/bromodomain expressed in Escherichia coli strains BL21 (DE3) cells using biotinylated H3K23ac (...More data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 7.90nMAssay Description:Inhibition of recombinant human His-tagged TRIM24-PHD/bromodomain expressed in Escherichia coli strains BL21 (DE3) cells using biotinylated H3K23ac (...More data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 8.30nMAssay Description:Inhibition of recombinant human His-tagged TRIM24-PHD/bromodomain expressed in Escherichia coli strains BL21 (DE3) cells using biotinylated H3K23ac (...More data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:The alpha assay was used to assess the binding of the compounds of the application to TRIM24 at various concentrations. All compounds were added at c...More data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:The alpha assay was used to assess the binding of the compounds of the application to TRIM24 at various concentrations. All compounds were added at c...More data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:The alpha assay was used to assess the binding of the compounds of the application to TRIM24 at various concentrations. All compounds were added at c...More data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:The alpha assay was used to assess the binding of the compounds of the application to TRIM24 at various concentrations. All compounds were added at c...More data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:The alpha assay was used to assess the binding of the compounds of the application to TRIM24 at various concentrations. All compounds were added at c...More data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:The alpha assay was used to assess the binding of the compounds of the application to TRIM24 at various concentrations. All compounds were added at c...More data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human His-tagged TRIM24-PHD/bromodomain expressed in Escherichia coli strains BL21 (DE3) cells using biotinylated H3K23ac (...More data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:The alpha assay was used to assess the binding of the compounds of the application to TRIM24 at various concentrations. All compounds were added at c...More data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:The alpha assay was used to assess the binding of the compounds of the application to TRIM24 at various concentrations. All compounds were added at c...More data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human His-tagged TRIM24-PHD/bromodomain expressed in Escherichia coli strains BL21 (DE3) cells using biotinylated H3K23ac (...More data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human His-tagged TRIM24-PHD/bromodomain expressed in Escherichia coli strains BL21 (DE3) cells using biotinylated H3K23ac (...More data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human His-tagged TRIM24-PHD/bromodomain expressed in Escherichia coli strains BL21 (DE3) cells using biotinylated H3K23ac (...More data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataKd: 31nMAssay Description:Binding affinity to recombinant human His-tagged TRIM24-PHD/bromodomain expressed in Escherichia coli strains BL21 (DE3) cells by isothermal titratio...More data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibition of recombinant human His-tagged TRIM24-PHD/bromodomain expressed in Escherichia coli strains BL21 (DE3) cells using biotinylated H3K23ac (...More data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataEC50: 50nMAssay Description:Inhibition of Flag-tagged TRIM24-PHD/bromodomain (unknown origin) expressed in human HeLa cells for 2 hrs by AlphaLisa assayMore data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 53nMAssay Description:Inhibition of recombinant human His-tagged TRIM24-PHD/bromodomain expressed in Escherichia coli strains BL21 (DE3) cells using biotinylated H3K23ac (...More data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:The alpha assay was used to assess the binding of the compounds of the application to TRIM24 at various concentrations. All compounds were added at c...More data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:The alpha assay was used to assess the binding of the compounds of the application to TRIM24 at various concentrations. All compounds were added at c...More data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:The alpha assay was used to assess the binding of the compounds of the application to TRIM24 at various concentrations. All compounds were added at c...More data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 57nMAssay Description:Inhibition of recombinant human His-tagged TRIM24-PHD/bromodomain expressed in Escherichia coli strains BL21 (DE3) cells using biotinylated H3K23ac (...More data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataEC50: 59nMAssay Description:Inhibition of Flag-tagged TRIM24-PHD/bromodomain (unknown origin) expressed in human HeLa cells for 2 hrs by AlphaLisa assayMore data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant human His-tagged TRIM24-PHD/bromodomain expressed in Escherichia coli strains BL21 (DE3) cells using biotinylated H3K23ac (...More data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human His-tagged TRIM24-PHD/bromodomain expressed in Escherichia coli strains BL21 (DE3) cells using biotinylated H3K23ac (...More data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant human His-tagged TRIM24-PHD/bromodomain expressed in Escherichia coli strains BL21 (DE3) cells using biotinylated H3K23ac (...More data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataEC50: 110nMAssay Description:Inhibition of Flag-tagged TRIM24-PHD/bromodomain (unknown origin) expressed in human HeLa cells for 2 hrs by AlphaLisa assayMore data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataEC50: 120nMAssay Description:Inhibition of Flag-tagged TRIM24-PHD/bromodomain (unknown origin) expressed in human HeLa cells for 2 hrs by AlphaLisa assayMore data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataEC50: 120nMAssay Description:Inhibition of Flag-tagged TRIM24-PHD/bromodomain (unknown origin) expressed in human HeLa cells for 2 hrs by AlphaLisa assayMore data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of recombinant human His-tagged TRIM24-PHD/bromodomain expressed in Escherichia coli strains BL21 (DE3) cells using biotinylated H3K23ac (...More data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of recombinant human His-tagged TRIM24-PHD/bromodomain expressed in Escherichia coli strains BL21 (DE3) cells using biotinylated H3K23ac (...More data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of TRIM24 (unknown origin) measured alphascreen assayMore data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of recombinant human His-tagged TRIM24-PHD/bromodomain expressed in Escherichia coli strains BL21 (DE3) cells using biotinylated H3K23ac (...More data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of recombinant human His-tagged TRIM24-PHD/bromodomain expressed in Escherichia coli strains BL21 (DE3) cells using biotinylated H3K23ac (...More data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataEC50: 170nMAssay Description:Inhibition of Flag-tagged TRIM24-PHD/bromodomain (unknown origin) expressed in human HeLa cells for 2 hrs by AlphaLisa assayMore data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataEC50: 170nMAssay Description:Inhibition of Flag-tagged TRIM24-PHD/bromodomain (unknown origin) expressed in human HeLa cells for 2 hrs by AlphaLisa assayMore data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of recombinant human His-tagged TRIM24-PHD/bromodomain expressed in Escherichia coli strains BL21 (DE3) cells using biotinylated H3K23ac (...More data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 218nMAssay Description:Inhibition of His-tagged TRIM24 (unknown origin) expressed in Escherichia coli BL21(DE3)pLysS competent cells using biotinylated-H3K23ac peptide as s...More data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Inhibition of recombinant human His-tagged TRIM24-PHD/bromodomain expressed in Escherichia coli strains BL21 (DE3) cells using biotinylated H3K23ac (...More data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataKd: 222nMAssay Description:Binding affinity to N-terminal His6-SUMO-1-tagged recombinant human TRIM24 bromodomain expressed in Escherichia coli BL21(DE3)-R3-pRARE2 cells by iso...More data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 270nMAssay Description:Inhibition of recombinant human His-tagged TRIM24-PHD/bromodomain expressed in Escherichia coli strains BL21 (DE3) cells using biotinylated H3K23ac (...More data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 270nMAssay Description:Inhibition of recombinant human His-tagged TRIM24-PHD/bromodomain expressed in Escherichia coli strains BL21 (DE3) cells using biotinylated H3K23ac (...More data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:The alpha assay was used to assess the binding of the compounds of the application to TRIM24 at various concentrations. All compounds were added at c...More data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:The alpha assay was used to assess the binding of the compounds of the application to TRIM24 at various concentrations. All compounds were added at c...More data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:The alpha assay was used to assess the binding of the compounds of the application to TRIM24 at various concentrations. All compounds were added at c...More data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 338nMAssay Description:Inhibition of His-tagged TRIM24 (unknown origin) expressed in Escherichia coli BL21(DE3)pLysS competent cells using biotinylated-H3K23ac peptide as s...More data for this Ligand-Target Pair


3D Structure (crystal)
































