Compile Data Set for Download or QSAR
Report error Found 348 Enz. Inhib. hit(s) with Target = 'Tissue alpha-L-fucosidase'
TargetTissue alpha-L-fucosidase(Bovine)
Université

Curated by ChEMBL
LigandPNGBDBM50179482((2R,3S,4R,5R,6S)-3,4,5-trihydroxy-6-methylpiperidi...)
Affinity DataKi:  1nMAssay Description:Inhibition of bovine alpha-L-fucosidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Bovine)
Université

Curated by ChEMBL
LigandPNGBDBM50179481(L-fuco-nojirimycin | CHEMBL203969)
Affinity DataKi:  1nMAssay Description:Inhibition of bovine alpha-L-fucosidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Bovine)
Université

Curated by ChEMBL
LigandPNGBDBM50304627((2S,3S,4R,5R,6S)-6-methylpiperidine-2,3,4,5-tetrao...)
Affinity DataKi:  1nMAssay Description:Inhibition of bovine kidney alpha-L-fucosidase by para-nitrophenolate release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50072685((3,4,5-Trihydroxy-2-hydroxymethyl-6-methyl-piperid...)
Affinity DataKi:  1.5nMAssay Description:Compound was tested for inhibitory activity against alpha-1,2-Fucosidase obtained from Arthrobacter oxidans F1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Bovine)
Université

Curated by ChEMBL
LigandPNGBDBM50065258(CHEMBL314772 | (2S,3R,4S,5R)-2-methylpiperidine-3,...)
Affinity DataKi:  1.70nMAssay Description:Inhibitory concentration against alpha-L-fucosidase of bovine epididymisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Bovine)
Université

Curated by ChEMBL
LigandPNGBDBM50065258(CHEMBL314772 | (2S,3R,4S,5R)-2-methylpiperidine-3,...)
Affinity DataKi:  3nMAssay Description:Inhibition of bovine kidney alpha-L-fucosidase by para-nitrophenolate release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50072685((3,4,5-Trihydroxy-2-hydroxymethyl-6-methyl-piperid...)
Affinity DataIC50: 4nMAssay Description:Compound was tested for inhibitory activity against alpha-1,2-Fucosidase obtained from Arthrobacter oxidansMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Bovine)
Université

Curated by ChEMBL
LigandPNGBDBM50065258(CHEMBL314772 | (2S,3R,4S,5R)-2-methylpiperidine-3,...)
Affinity DataIC50: 5nMAssay Description:Inhibition of bovine alpha-L-fucosidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50104394((4S,5R)-2-Methyl-piperidine-3,4,5-triol | CHEMBL87...)
Affinity DataKi:  5nMAssay Description:In vitro inhibition of alpha-L-fucosidase isolated from bovine kidney.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Bovine)
Université

Curated by ChEMBL
LigandPNGBDBM50065257(beta-homofuconojirimycin | (2R,3R,4R,5R,6S)-2-Hydr...)
Affinity DataKi:  5.30nMAssay Description:Inhibition of bovine epididymis alpha-L-fucosidase assessed as p-nitrophenol release by spectrophotometricallyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Bovine)
Université

Curated by ChEMBL
LigandPNGBDBM50065257(beta-homofuconojirimycin | (2R,3R,4R,5R,6S)-2-Hydr...)
Affinity DataKi:  5.30nMAssay Description:Inhibitory concentration against alpha-L-fucosidase of bovine epididymisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50072588((2S,3R,4R,5R,6S)-2-Hydroxymethyl-6-methyl-piperidi...)
Affinity DataKi:  5.80nMAssay Description:Compound was tested for inhibitory activity (competitive) against alpha-L-fucosidase from bovine kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50072588((2S,3R,4R,5R,6S)-2-Hydroxymethyl-6-methyl-piperidi...)
Affinity DataKi:  5.80nMAssay Description:Inhibitory activity against alpha-L-fucosidase in bovine epididymis; Competitive Inhibition typeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50072588((2S,3R,4R,5R,6S)-2-Hydroxymethyl-6-methyl-piperidi...)
Affinity DataKi:  5.80nMAssay Description:Tested for inhibitory activity against alpha-L-fucosidase from bovine epididymus (sigma)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50104394((4S,5R)-2-Methyl-piperidine-3,4,5-triol | CHEMBL87...)
Affinity DataKi:  6nMAssay Description:Inhibitory activity against alpha-L-fucosidase of bovine epididymis expressed as KiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50065258(CHEMBL314772 | (2S,3R,4S,5R)-2-methylpiperidine-3,...)
Affinity DataKi:  6.20nMAssay Description:Inhibitory activity against alpha-L-fucosidase in bovine epididymis; Competitive Inhibition typeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50065258(CHEMBL314772 | (2S,3R,4S,5R)-2-methylpiperidine-3,...)
Affinity DataKi:  6.20nMAssay Description:Tested for inhibitory activity against alpha-L-fucosidase from bovine epididymus (sigma)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50065258(CHEMBL314772 | (2S,3R,4S,5R)-2-methylpiperidine-3,...)
Affinity DataKi:  6.20nMAssay Description:Compound was tested for inhibitory activity (competitive) against alpha-L-fucosidase from bovine kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50104387((4R,5R)-6-Hydroxymethyl-2-methyl-2,3,4,5-tetrahydr...)
Affinity DataKi:  7nMAssay Description:Inhibitory activity against alpha-L-fucosidase of bovine epididymis expressed as KiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50442341(CHEMBL2442786)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of human lysosome alpha-L-fucosidase using 4-methylumbelliferyl-alpha-L-fucopyranoside by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50072685((3,4,5-Trihydroxy-2-hydroxymethyl-6-methyl-piperid...)
Affinity DataKi:  8nMAssay Description:Compound was tested for inhibitory activity against alpha-Fucosidase obtained from Bovine epididymisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50104405(3,4-Dihydroxy-5-methyl-pyrrolidine-2-sulfonic acid...)
Affinity DataKi:  10nMAssay Description:Inhibitory concentration against alpha-L-Fucosidase of human placentaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50065258(CHEMBL314772 | (2S,3R,4S,5R)-2-methylpiperidine-3,...)
Affinity DataKi:  10nMAssay Description:Inhibition of human liver alpha-L-fucosidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Bovine)
Université

Curated by ChEMBL
LigandPNGBDBM50304628((2S,3R,4S)-2-methyl-3,4-dihydro-2H-pyrrole-3,4-dio...)
Affinity DataKi:  10nMAssay Description:Inhibition of bovine kidney alpha-L-fucosidase by para-nitrophenolate release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50072685((3,4,5-Trihydroxy-2-hydroxymethyl-6-methyl-piperid...)
Affinity DataIC50: 11nMAssay Description:Compound was tested for inhibitory activity against alpha-Fucosidase obtained from Bovine epididymisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50072685((3,4,5-Trihydroxy-2-hydroxymethyl-6-methyl-piperid...)
Affinity DataIC50: 11nMAssay Description:Compound was tested for inhibitory activity against alpha-Fucosidase obtained from Bovine kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50072685((3,4,5-Trihydroxy-2-hydroxymethyl-6-methyl-piperid...)
Affinity DataKi:  11nMAssay Description:Compound was tested for inhibitory activity against alpha-Fucosidase obtained from Bovine kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Bovine)
Université

Curated by ChEMBL
LigandPNGBDBM50442341(CHEMBL2442786)
Affinity DataIC50: 12nMAssay Description:Inhibition of bovine kidney alpha-L-fucosidase assessed as inhibition of release of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50403994(CHEMBL2114287)
Affinity DataKi:  12nMAssay Description:The compound was tested for the inhibitory activity against alpha-L-Fucosidase in bovine kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50442339(CHEMBL2442788)
Affinity DataIC50: 14nMAssay Description:Inhibition of human lysosome alpha-L-fucosidase using 4-methylumbelliferyl-alpha-L-fucopyranoside by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50442344(CHEMBL2442783)
Affinity DataIC50: 15nMAssay Description:Inhibition of human lysosome alpha-L-fucosidase using 4-methylumbelliferyl-alpha-L-fucopyranoside by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50104403((2R,3S)-2-Amino-5-methyl-piperidine-3,4-diol | CHE...)
Affinity DataKi:  16nMAssay Description:Inhibitory concentration against alpha-L-Fucosidase of human placentaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50118923(4-Methyl-6-octylamino-cyclohexane-1,2,3-triol | (1...)
Affinity DataKi:  16nMAssay Description:Binding affinity against alpha-L-fucosidase in bovine kidney was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM394396(US10308607, Compound II)
Affinity DataIC50: 16nMAssay Description:Fucosidase inhibition was assessed by preparing a reaction mixture of 50 mM phosphate-citrate pH 4.5, 5 mM MgCl2, 640 nM 4-methylumbelliferyl-alpha-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
Go to US Patent

TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50072687((S)-2-Amino-3-hydroxy-N-(3,4,5-trihydroxy-2-hydrox...)
Affinity DataKi:  19nMAssay Description:Compound was tested for inhibitory activity against alpha-Fucosidase obtained from Bovine epididymisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50442343(CHEMBL2442784)
Affinity DataIC50: 19nMAssay Description:Inhibition of human lysosome alpha-L-fucosidase using 4-methylumbelliferyl-alpha-L-fucopyranoside by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50072687((S)-2-Amino-3-hydroxy-N-(3,4,5-trihydroxy-2-hydrox...)
Affinity DataIC50: 20nMAssay Description:Compound was tested for inhibitory activity against alpha-Fucosidase obtained from Bovine epididymisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Bovine)
Université

Curated by ChEMBL
LigandPNGBDBM50442343(CHEMBL2442784)
Affinity DataIC50: 21nMAssay Description:Inhibition of bovine kidney alpha-L-fucosidase assessed as inhibition of release of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50442348(CHEMBL2442779)
Affinity DataIC50: 26nMAssay Description:Inhibition of human lysosome alpha-L-fucosidase using 4-methylumbelliferyl-alpha-L-fucopyranoside by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Bovine)
Université

Curated by ChEMBL
LigandPNGBDBM50442344(CHEMBL2442783)
Affinity DataIC50: 26nMAssay Description:Inhibition of bovine kidney alpha-L-fucosidase assessed as inhibition of release of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Bovine)
Université

Curated by ChEMBL
LigandPNGBDBM50442340(CHEMBL2442787)
Affinity DataIC50: 28nMAssay Description:Inhibition of bovine kidney alpha-L-fucosidase assessed as inhibition of release of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50065258(CHEMBL314772 | (2S,3R,4S,5R)-2-methylpiperidine-3,...)
Affinity DataKi:  29nMAssay Description:Inhibition constant against Alpha-Fucosidase; Uncompetitive inhibitionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2012
Entry Details Article

TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50442350(CHEMBL2442777)
Affinity DataIC50: 30nMAssay Description:Inhibition of human lysosome alpha-L-fucosidase using 4-methylumbelliferyl-alpha-L-fucopyranoside by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50072687((S)-2-Amino-3-hydroxy-N-(3,4,5-trihydroxy-2-hydrox...)
Affinity DataKi:  30nMAssay Description:Compound was tested for inhibitory activity against alpha-Fucosidase obtained from Bovine kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Bovine)
Université

Curated by ChEMBL
LigandPNGBDBM50442339(CHEMBL2442788)
Affinity DataIC50: 30nMAssay Description:Inhibition of bovine kidney alpha-L-fucosidase assessed as inhibition of release of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50442345(CHEMBL2442782)
Affinity DataIC50: 30nMAssay Description:Inhibition of human lysosome alpha-L-fucosidase using 4-methylumbelliferyl-alpha-L-fucopyranoside by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50065258(CHEMBL314772 | (2S,3R,4S,5R)-2-methylpiperidine-3,...)
Affinity DataKi:  31nMAssay Description:Binding affinity against alpha-L-fucosidase in bovine kidney was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50442340(CHEMBL2442787)
Affinity DataIC50: 31nMAssay Description:Inhibition of human lysosome alpha-L-fucosidase using 4-methylumbelliferyl-alpha-L-fucopyranoside by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50118928((1S,2S,3R)-4-Methyl-6-phenethylamino-cyclohexane-1...)
Affinity DataKi:  32nMAssay Description:Binding affinity against alpha-L-fucosidase in bovine kidney was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50442338(CHEMBL2442773)
Affinity DataIC50: 35nMAssay Description:Inhibition of human lysosome alpha-L-fucosidase using 4-methylumbelliferyl-alpha-L-fucopyranoside by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
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