Compile Data Set for Download or QSAR
Report error Found 306 Enz. Inhib. hit(s) with Target = 'Thyrotropin-releasing hormone receptor'
TargetThyrotropin-releasing hormone receptor(Mouse)
Washington University

Curated by ChEMBL
LigandPNGBDBM50050532(1-[2-[2-oxo-(5S)-dihydro-2H-5-pyrrolylcarboxamido]...)
Affinity DataEC50:  110nMAssay Description:Effective concentration required to activate TRH-R receptor in AtT-20 mouse pituitary tumor cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
Washington University

Curated by ChEMBL
LigandPNGBDBM50050529((S)-1-[2-((5R,7R)-2,6-Dioxo-1,7-diaza-spiro[4.4]no...)
Affinity DataEC50:  290nMAssay Description:Effective concentration required to activate TRH-R receptor in AtT-20 mouse pituitary tumor cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
Washington University

Curated by ChEMBL
LigandPNGBDBM50072396(7-cyclohexyl-6-(2,6-dioxo-1,7-diazaspiro[4.4]non-7...)
Affinity DataEC50:  1.80E+3nMAssay Description:Ability to activate thyroliberin endocrine receptor (TRH-R) using AtT-20 mouse pituitary tumor cells prelabelled with myo-[3H] inositolMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyrotropin-releasing hormone receptor(Rat)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50173824(1-[3-{2-[1-(1-adamantyl)ethyl]-1H-4-imidazolyl}-2-...)
Affinity DataEC50: >1.00E+5nMpH: 7.8Assay Description:Signaling (activation) potency for thyrotropin releasing hormone receptor 2 expressed in HEK 293EM cells with CREB-luciferase reporter upon incubatio...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyrotropin-releasing hormone receptor(Rat)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50072394(PROTIRELIN | ABBOTT-38579 | A-38579 | 1-[3-(1H-4-i...)
Affinity DataEC50:  3nMpH: 7.8Assay Description:Signaling (activation) potency for thyrotropin releasing hormone receptor 1 expressed in HEK 293EM cells with CREB-luciferase reporter upon incubatio...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyrotropin-releasing hormone receptor(Rat)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50173821(1-[3-[2-(tert-butyl)-1H-4-imidazolyl]-2-[5-oxo-(2S...)
Affinity DataEC50:  1.30E+3nMpH: 7.8Assay Description:Signaling (activation) potency for thyrotropin releasing hormone receptor 2 expressed in HEK 293EM cells with CREB-luciferase reporter upon incubatio...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyrotropin-releasing hormone receptor(Rat)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50173827(1-[3-(2-cyclopropyl-1H-4-imidazolyl)-2-[5-oxo-(2S)...)
Affinity DataEC50: >1.00E+5nMpH: 7.8Assay Description:Signaling (activation) potency for thyrotropin releasing hormone receptor 1 expressed in HEK 293EM cells with CREB-luciferase reporter upon incubatio...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyrotropin-releasing hormone receptor(Rat)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50173821(1-[3-[2-(tert-butyl)-1H-4-imidazolyl]-2-[5-oxo-(2S...)
Affinity DataEC50: >1.00E+5nMpH: 7.8Assay Description:Signaling (activation) potency for thyrotropin releasing hormone receptor 1 expressed in HEK 293EM cells with CREB-luciferase reporter upon incubatio...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyrotropin-releasing hormone receptor(Rat)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50173828(1-[2-[5-oxo-(2S)-tetrahydro-1H-2-pyrrolylcarboxami...)
Affinity DataEC50:  290nMpH: 7.8Assay Description:Signaling (activation) potency for thyrotropin releasing hormone receptor 1 expressed in HEK 293EM cells with CREB-luciferase reporter upon incubatio...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyrotropin-releasing hormone receptor(Rat)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50173825(1-[3-(2-isopropyl-1H-4-imidazolyl)-2-[5-oxo-(2S)-t...)
Affinity DataEC50:  1.50E+3nMpH: 7.8Assay Description:Signaling (activation) potency for thyrotropin releasing hormone receptor 2 expressed in HEK 293EM cells with CREB-luciferase reporter upon incubatio...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyrotropin-releasing hormone receptor(Rat)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50173822(1-[3-(2-cyclohexyl-1H-4-imidazolyl)-2-[5-oxo-(2S)-...)
Affinity DataEC50: >1.00E+5nMpH: 7.8Assay Description:Signaling (activation) potency for thyrotropin releasing hormone receptor 1 expressed in HEK 293EM cells with CREB-luciferase reporter upon incubatio...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyrotropin-releasing hormone receptor(Rat)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50072394(PROTIRELIN | ABBOTT-38579 | A-38579 | 1-[3-(1H-4-i...)
Affinity DataEC50:  3nMpH: 7.8Assay Description:Signaling (activation) potency for thyrotropin releasing hormone receptor 2 expressed in HEK 293EM cells with CREB-luciferase reporter upon incubatio...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyrotropin-releasing hormone receptor(Rat)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50173824(1-[3-{2-[1-(1-adamantyl)ethyl]-1H-4-imidazolyl}-2-...)
Affinity DataEC50: >1.00E+5nMpH: 7.8Assay Description:Signaling (activation) potency for thyrotropin releasing hormone receptor 1 expressed in HEK 293EM cells with CREB-luciferase reporter upon incubatio...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyrotropin-releasing hormone receptor(Rat)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50173822(1-[3-(2-cyclohexyl-1H-4-imidazolyl)-2-[5-oxo-(2S)-...)
Affinity DataEC50:  1.10E+3nMpH: 7.8Assay Description:Signaling (activation) potency for thyrotropin releasing hormone receptor 2 expressed in HEK 293EM cells with CREB-luciferase reporter upon incubatio...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyrotropin-releasing hormone receptor(Rat)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50173825(1-[3-(2-isopropyl-1H-4-imidazolyl)-2-[5-oxo-(2S)-t...)
Affinity DataEC50: >1.00E+5nMpH: 7.8Assay Description:Signaling (activation) potency for thyrotropin releasing hormone receptor 1 expressed in HEK 293EM cells with CREB-luciferase reporter upon incubatio...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyrotropin-releasing hormone receptor(Rat)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50173828(1-[2-[5-oxo-(2S)-tetrahydro-1H-2-pyrrolylcarboxami...)
Affinity DataEC50:  24nMpH: 7.8Assay Description:Signaling (activation) potency for thyrotropin releasing hormone receptor 2 expressed in HEK 293EM cells with CREB-luciferase reporter upon incubatio...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyrotropin-releasing hormone receptor(Rat)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50173827(1-[3-(2-cyclopropyl-1H-4-imidazolyl)-2-[5-oxo-(2S)...)
Affinity DataEC50:  410nMpH: 7.8Assay Description:Signaling (activation) potency for thyrotropin releasing hormone receptor 2 expressed in HEK 293EM cells with CREB-luciferase reporter upon incubatio...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyrotropin-releasing hormone receptor(Rat)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50173826(1-[(S)-2-Amino-3-(3-methyl-3H-imidazol-4-yl)-propi...)
Affinity DataEC50:  0.5nMpH: 7.8Assay Description:Signaling (activation) potency for thyrotropin releasing hormone receptor 1 expressed in HEK 293EM cells with CREB-luciferase reporter upon incubatio...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyrotropin-releasing hormone receptor(Human)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50196446([N tau(1)-Me-His]-TRH | CHEMBL224730)
Affinity DataEC50:  5nMAssay Description:Agonist activity at TRHR1 expressed in HEK293EM cells assessed as activation potency by measuring CREB-luciferase reporter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyrotropin-releasing hormone receptor(Human)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50196445((2S)-1-[(2S)-2-(2S)-6-oxohexahydro-2-pyridinylcarb...)
Affinity DataEC50:  380nMAssay Description:Agonist activity at TRHR1 expressed in HEK293EM cells assessed as activation potency by measuring CREB-luciferase reporter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyrotropin-releasing hormone receptor(Human)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50196447((2S)-1-[(2S)-2-(2S)-6-oxohexahydro-2-pyridinylcarb...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at TRHR1 expressed in HEK293EM cells assessed as activation potency by measuring CREB-luciferase reporter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyrotropin-releasing hormone receptor(Human)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50072394(PROTIRELIN | ABBOTT-38579 | A-38579 | 1-[3-(1H-4-i...)
Affinity DataEC50:  3nMAssay Description:Agonist activity at TRHR1 expressed in HEK293EM cells assessed as activation potency by measuring CREB-luciferase reporter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyrotropin-releasing hormone receptor(Rat)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50196448((2S)-1-[(2S)-2-(1R)-3-oxocyclopentylcarboxamido]-3...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at TRHR2 expressed in HEK293EM cells assessed as activation potency by measuring CREB-luciferase reporter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyrotropin-releasing hormone receptor(Rat)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50196449((2S)-1-{(2S)-3-(1-allyl-1H-4-imidazolyl)-2-[(2S)-6...)
Affinity DataEC50:  340nMAssay Description:Agonist activity at TRHR2 expressed in HEK293EM cells assessed as activation potency by measuring CREB-luciferase reporter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyrotropin-releasing hormone receptor(Rat)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50072394(PROTIRELIN | ABBOTT-38579 | A-38579 | 1-[3-(1H-4-i...)
Affinity DataEC50:  3nMAssay Description:Agonist activity at TRHR2 expressed in HEK293EM cells assessed as activation potency by measuring CREB-luciferase reporter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyrotropin-releasing hormone receptor(Human)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50196451((2S)-1-{(2S)-3-(1-methyl-1H-4-imidazolyl)-2-[(2S)-...)
Affinity DataEC50:  4.90nMAssay Description:Agonist activity at TRHR1 expressed in HEK293EM cells assessed as activation potency by measuring CREB-luciferase reporter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyrotropin-releasing hormone receptor(Rat)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50196454((2S)-1-[(2S)-2-(1R)-3-oxocyclopentylcarboxamido]-3...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at TRHR2 expressed in HEK293EM cells assessed as activation potency by measuring CREB-luciferase reporter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyrotropin-releasing hormone receptor(Rat)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50196456((2S)-1-[(2S)-2-(2S)-6-oxohexahydro-2-pyridinylcarb...)
Affinity DataEC50:  1.90E+3nMAssay Description:Agonist activity at TRHR2 expressed in HEK293EM cells assessed as activation potency by measuring CREB-luciferase reporter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyrotropin-releasing hormone receptor(Human)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50196454((2S)-1-[(2S)-2-(1R)-3-oxocyclopentylcarboxamido]-3...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at TRHR1 expressed in HEK293EM cells assessed as activation potency by measuring CREB-luciferase reporter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyrotropin-releasing hormone receptor(Human)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50196458((2S)-1-{(2S)-3-(1-benzyl-1H-4-imidazolyl)-2-[(2S)-...)
Affinity DataEC50:  1.70E+4nMAssay Description:Agonist activity at TRHR1 expressed in HEK293EM cells assessed as activation potency by measuring CREB-luciferase reporter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyrotropin-releasing hormone receptor(Rat)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50196447((2S)-1-[(2S)-2-(2S)-6-oxohexahydro-2-pyridinylcarb...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at TRHR2 expressed in HEK293EM cells assessed as activation potency by measuring CREB-luciferase reporter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyrotropin-releasing hormone receptor(Human)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50196453((2S)-1-[(2S)-2-(1S)-3-oxocyclopentylcarboxamido]-3...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at TRHR1 expressed in HEK293EM cells assessed as activation potency by measuring CREB-luciferase reporter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyrotropin-releasing hormone receptor(Rat)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50196458((2S)-1-{(2S)-3-(1-benzyl-1H-4-imidazolyl)-2-[(2S)-...)
Affinity DataEC50:  2.00E+3nMAssay Description:Agonist activity at TRHR2 expressed in HEK293EM cells assessed as activation potency by measuring CREB-luciferase reporter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyrotropin-releasing hormone receptor(Human)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50196457((2S)-1-{(2S)-3-(1-ethyl-1H-4-imidazolyl)-2-[(2S)-6...)
Affinity DataEC50:  14nMAssay Description:Agonist activity at TRHR1 expressed in HEK293EM cells assessed as activation potency by measuring CREB-luciferase reporter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyrotropin-releasing hormone receptor(Rat)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50196460((2S)-1-[(2S)-2-(1S)-3-oxocyclopentylcarboxamido]-3...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at TRHR2 expressed in HEK293EM cells assessed as activation potency by measuring CREB-luciferase reporter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyrotropin-releasing hormone receptor(Human)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50196461((2S)-1-[(2S)-2-(1R)-3-oxocyclopentylcarboxamido]-3...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at TRHR1 expressed in HEK293EM cells assessed as activation potency by measuring CREB-luciferase reporter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyrotropin-releasing hormone receptor(Rat)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50196450((2S)-1-[(2S)-2-(1R)-3-oxocyclopentylcarboxamido]-3...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at TRHR2 expressed in HEK293EM cells assessed as activation potency by measuring CREB-luciferase reporter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyrotropin-releasing hormone receptor(Rat)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50196461((2S)-1-[(2S)-2-(1R)-3-oxocyclopentylcarboxamido]-3...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at TRHR2 expressed in HEK293EM cells assessed as activation potency by measuring CREB-luciferase reporter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyrotropin-releasing hormone receptor(Rat)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50196445((2S)-1-[(2S)-2-(2S)-6-oxohexahydro-2-pyridinylcarb...)
Affinity DataEC50:  29nMAssay Description:Agonist activity at TRHR2 expressed in HEK293EM cells assessed as activation potency by measuring CREB-luciferase reporter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyrotropin-releasing hormone receptor(Human)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50196455((2S)-1-[(2S)-2-(1S)-3-oxocyclopentylcarboxamido]-3...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at TRHR1 expressed in HEK293EM cells assessed as activation potency by measuring CREB-luciferase reporter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyrotropin-releasing hormone receptor(Human)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50196460((2S)-1-[(2S)-2-(1S)-3-oxocyclopentylcarboxamido]-3...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at TRHR1 expressed in HEK293EM cells assessed as activation potency by measuring CREB-luciferase reporter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyrotropin-releasing hormone receptor(Human)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50196452((2S)-1-[(2S)-2-(1S)-3-oxocyclopentylcarboxamido]-3...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at TRHR1 expressed in HEK293EM cells assessed as activation potency by measuring CREB-luciferase reporter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyrotropin-releasing hormone receptor(Rat)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50196459((2S)-1-[(2S)-2-(2S)-6-oxohexahydro-2-pyridinylcarb...)
Affinity DataEC50:  3.30E+3nMAssay Description:Agonist activity at TRHR2 expressed in HEK293EM cells assessed as activation potency by measuring CREB-luciferase reporter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyrotropin-releasing hormone receptor(Human)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50196449((2S)-1-{(2S)-3-(1-allyl-1H-4-imidazolyl)-2-[(2S)-6...)
Affinity DataEC50:  5.10E+3nMAssay Description:Agonist activity at TRHR1 expressed in HEK293EM cells assessed as activation potency by measuring CREB-luciferase reporter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyrotropin-releasing hormone receptor(Rat)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50196453((2S)-1-[(2S)-2-(1S)-3-oxocyclopentylcarboxamido]-3...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at TRHR2 expressed in HEK293EM cells assessed as activation potency by measuring CREB-luciferase reporter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyrotropin-releasing hormone receptor(Rat)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50196457((2S)-1-{(2S)-3-(1-ethyl-1H-4-imidazolyl)-2-[(2S)-6...)
Affinity DataEC50:  2.80nMAssay Description:Agonist activity at TRHR2 expressed in HEK293EM cells assessed as activation potency by measuring CREB-luciferase reporter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyrotropin-releasing hormone receptor(Human)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50196459((2S)-1-[(2S)-2-(2S)-6-oxohexahydro-2-pyridinylcarb...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at TRHR1 expressed in HEK293EM cells assessed as activation potency by measuring CREB-luciferase reporter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyrotropin-releasing hormone receptor(Human)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50196450((2S)-1-[(2S)-2-(1R)-3-oxocyclopentylcarboxamido]-3...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at TRHR1 expressed in HEK293EM cells assessed as activation potency by measuring CREB-luciferase reporter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyrotropin-releasing hormone receptor(Rat)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50196452((2S)-1-[(2S)-2-(1S)-3-oxocyclopentylcarboxamido]-3...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at TRHR2 expressed in HEK293EM cells assessed as activation potency by measuring CREB-luciferase reporter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyrotropin-releasing hormone receptor(Human)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50196456((2S)-1-[(2S)-2-(2S)-6-oxohexahydro-2-pyridinylcarb...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at TRHR1 expressed in HEK293EM cells assessed as activation potency by measuring CREB-luciferase reporter activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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