Compile Data Set for Download or QSAR
Report error Found 428 Enz. Inhib. hit(s) with Target = 'Thioredoxin reductase'
TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM50633100(CHEMBL5412818)
Affinity DataEC50:  1.31E+4nMAssay Description:Inhibition of TrxR1 in human HeLa cells incubated for 24 hrsMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM50633100(CHEMBL5412818)
Affinity DataEC50:  3.14E+3nMAssay Description:Inhibition of TrxR1 in human HCT-116 cells incubated for 24 hrsMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Mus musculus)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM50633100(CHEMBL5412818)
Affinity DataEC50:  2.57E+4nMAssay Description:Inhibition of TrxR1 in mouse CT26 cells incubated for 24 hrsMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM501863(US11028067, Example 4)
Affinity DataIC50: 0.854nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM522169(US11161815, Example 25)
Affinity DataIC50: 1.03nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM522162(US11161815, Example 18)
Affinity DataIC50: 1.52nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM531217(US11208384, Example 1)
Affinity DataIC50: 3.16nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM501865(US11028067, Example 6)
Affinity DataIC50: 3.99nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM522165(US11161815, Example 21)
Affinity DataIC50: 4.35nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM522166(US11161815, Example 22)
Affinity DataIC50: 5.05nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM501860(US11028067, Example 8 | US11028067, Example 1)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM522173(US11161815, Example 29)
Affinity DataIC50: 6.78nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM501866(US11028067, Example 7)
Affinity DataIC50: 6.90nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM522164(US11161815, Example 20)
Affinity DataIC50: 7.16nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM522171(US11161815, Example 27)
Affinity DataIC50: 7.33nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM522163(US11161815, Example 19)
Affinity DataIC50: 7.60nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM50576853(CHEMBL4859206)
Affinity DataIC50: 9.20nMAssay Description:Inhibition of TrxR1 (unknown origin) assessed as reduction in DTNB to TNB by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM50576853(CHEMBL4859206)
Affinity DataIC50: 9.20nMAssay Description:Inhibition of TrxR1 (unknown origin) assessed as reduction in DTNB to TNB by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM501864(US11028067, Example 5)
Affinity DataIC50: 10.8nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM522156(US11161815, Example 12)
Affinity DataIC50: 12.3nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM50576851(CHEMBL1876217)
Affinity DataIC50: 13nMAssay Description:Inhibition of TrxR1 (unknown origin) assessed as reduction in DTNB to TNB by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM50576851(CHEMBL1876217)
Affinity DataIC50: 13nMAssay Description:Inhibition of TrxR1 (unknown origin) assessed as reduction in DTNB to TNB by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM522167(US11161815, Example 23)
Affinity DataIC50: 14.5nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM50576852(CHEMBL4849098)
Affinity DataIC50: 18nMAssay Description:Inhibition of TrxR1 (unknown origin) assessed as reduction in DTNB to TNB by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM50576852(CHEMBL4849098)
Affinity DataIC50: 18nMAssay Description:Inhibition of TrxR1 (unknown origin) assessed as reduction in DTNB to TNB by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM522145(US11161815, Example 1)
Affinity DataIC50: 18.2nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM522170(US11161815, Example 26)
Affinity DataIC50: 18.8nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM522172(US11161815, Example 28)
Affinity DataIC50: 20.3nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM522168(US11161815, Example 24)
Affinity DataIC50: 25.3nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM501860(US11028067, Example 8 | US11028067, Example 1)
Affinity DataIC50: 26.8nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM524190(US11168069, Example 3)
Affinity DataIC50: 39.1nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM522148(US11161815, Example 4)
Affinity DataIC50: 39.2nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 43nMAssay Description:Inhibition of TrxR1 (unknown origin) assessed as reduction in DTNB to TNB by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM522150(US11161815, Example 6)
Affinity DataIC50: 56nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM501861(US11028067, Example 2)
Affinity DataIC50: 56.9nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM522160(US11161815, Example 16)
Affinity DataIC50: 60.6nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM522174(US11161815, Example 30)
Affinity DataIC50: 66.9nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM522176(US11161815, Example 32)
Affinity DataIC50: 76.5nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM524188(US11168069, Example 1)
Affinity DataIC50: 93nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM522158(US11161815, Example 14)
Affinity DataIC50: 96.9nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM522161(US11161815, Example 17)
Affinity DataIC50: 103nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM522159(US11161815, Example 15)
Affinity DataIC50: 122nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM522154(US11161815, Example 10)
Affinity DataIC50: 124nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50385274(CHEMBL2035489)
Affinity DataIC50: 130nMAssay Description:Inhibition of TrxR1 in rat liver homogenate preincubated for 5 mins measured by DNTB assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM522175(US11161815, Example 31)
Affinity DataIC50: 131nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM522157(US11161815, Example 13)
Affinity DataIC50: 160nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM522149(US11161815, Example 5)
Affinity DataIC50: 181nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM522152(US11161815, Example 8)
Affinity DataIC50: 188nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50551265(CHEMBL4792536)
Affinity DataIC50: 190nMAssay Description:Inhibition of recombinant rat TrxR1 using DTNB as substrate preincubated for 15 mins followed by substrate addition and measured for 20 mins by color...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM50547497(CHEMBL4757091)
Affinity DataIC50: 200nMAssay Description:Inhibition of TrxR in human BEL-7402/5-FU cells by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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